{"id":455602,"date":"2026-07-22T19:24:00","date_gmt":"2026-07-22T11:24:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=455602"},"modified":"2026-07-22T19:24:00","modified_gmt":"2026-07-22T11:24:00","slug":"%e7%91%9e%e5%8d%9a%e7%94%9f%e7%89%a9%e6%8a%ab%e9%9c%b2%e5%85%a8%e7%90%83%e9%a6%96%e5%80%8b%e9%9d%b6%e5%90%91fxi%e7%9a%84sirna%e8%97%a5%e7%89%a9vortosiran%e7%9a%84iia%e6%9c%9f%e8%87%a8%e5%ba%8a","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=455602","title":{"rendered":"\u745e\u535a\u751f\u7269\u62ab\u9732\u5168\u7403\u9996\u500b\u9776\u5411FXI\u7684siRNA\u85e5\u7269vortosiran\u7684IIa\u671f\u81e8\u5e8a\u7a4d\u6975\u6578\u64da"},"content":{"rendered":"<div>\n<table name=\"logo_release\" border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legendSpanClass\">\u4e2d\u570b\u4e0a\u6d77\u548c\u745e\u5178\u9ed8\u6069\u9054\u723e<\/span><span class=\"legendSpanClass\">2026\u5e747\u670822\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u8607\u5dde\u745e\u535a\u751f\u7269\u6280\u8853\u80a1\u4efd\u6709\u9650\u516c\u53f8 (06938.HK) \u53ca\u5176\u5b50\u516c\u53f8Ribocure Pharmaceuticals\uff08\u5408\u7a31\u300c\u745e\u535a\u751f\u7269\u300d\uff09\u4eca\u65e5\u5728\u4e0a\u6d77\u8209\u884c\u7684\u5927\u570b\u65b0\u85e5\u5168\u7403\u6703\u8b70\uff08CPIC\uff09\u4e0a\uff0c\u9996\u6b21\u516c\u4f48\u5176\u9776\u5411\u51dd\u8840\u56e0\u5b50XI (FXI) \u7684siRNA\u5019\u9078\u85e5\u7269vortosiran (RBD4059) \u5728\u6b50\u6d32\u5b8c\u6210\u7684\u4e00\u9805 \u91dd\u5c0d\u6162\u6027\u51a0\u72c0\u52d5\u8108\u75be\u75c5\uff08CAD\uff09\u60a3\u8005\u7684IIa\u671f\u81e8\u5e8a\u7814\u7a76\u7684\u7a4d\u6975\u7d50\u679c\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">  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siRNA\u81e8\u5e8a\u6982\u5ff5\u9a57\u8b49\uff0c\u652f\u6301vortosiran\u4f5c\u70ba\u5dee\u7570\u5316\u3001\u9577\u6548\u6297\u8840\u6813\u7642\u6cd5\u7684\u958b\u767c\u6f5b\u529b\u3002\u901a\u904e\u9776\u5411FXI\uff0cvortosiran\u964d\u4f4e\u8840\u6813\u5f62\u6210\u98a8\u96aa\uff0c\u540c\u6642\u4fdd\u7559\u6a5f\u9ad4\u6b62\u8840\u529f\u80fd\uff0c\u6709\u671b\u89e3\u6c7a\u5fc3\u8840\u7ba1\u75be\u75c5\u9818\u57df\u7684\u91cd\u5927\u672a\u6eff\u8db3\u91ab\u7642\u9700\u6c42\u3002<\/p>\n<p>\u745e\u535a\u751f\u7269\u806f\u5e2dCEO\u517c\u5168\u7403\u7814\u767c\u7e3d\u88c1\u7518\u9ece\u660e\u535a\u58eb\u8868\u793a\uff1a\u300c\u5728\u4e0d\u589e\u52a0\u51fa\u8840\u98a8\u96aa\u7684\u524d\u63d0\u4e0b\u9810\u9632\u8840\u6813\u5f62\u6210\uff0c\u4e00\u76f4\u662f\u5fc3\u8840\u7ba1\u91ab\u5b78\u9818\u57df\u9577\u671f\u4ee5\u4f86\u5922\u5bd0\u4ee5\u6c42\u7684\u300e\u91ab\u5b78\u8056\u76c3\u300f\u3002\u672c\u6b21IIa\u671f\u81e8\u5e8a\u6578\u64da\u9032\u4e00\u6b65\u592f\u5be6\u4e86\u6211\u5011\u7684\u5805\u5b9a\u4fe1\u5ff5\uff0c\u5373\u5c0d\u65bc\u8840\u6813\u6813\u585e\u6027\u75be\u75c5\u800c\u8a00\uff0cvortosiran\u662f\u4e00\u7a2e\u5b89\u5168\u4e14\u5177\u6709\u986f\u8457\u5dee\u7570\u5316\u512a\u52e2\u7684FXI\u6291\u5236\u7642\u6cd5\u3002\u57fa\u65bc\u9019\u4e9b\u7814\u7a76\u7d50\u679c\uff0c\u6211\u5011\u5df2\u555f\u52d5\u4e86\u4e00\u500b\u5305\u542b\u591a\u9805IIb\u671f\u8a66\u9a57\u5728\u5167\u7684ORBIT-XI 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(<\/b><b>RBD4059)<\/b><\/p>\n<p>Vortosiran\u662f\u745e\u535a\u751f\u7269\u57fa\u65bcRiboGalSTAR\u2122\u809d\u9776\u5411\u6280\u8853\u5e73\u53f0\u81ea\u4e3b\u7814\u767c\u7684\u5168\u7403\u9996\u5275\u9776\u5411FXI\u7684siRNA\u85e5\u7269\uff0c\u901a\u904e\u7279\u7570\u6027\u6291\u5236FXI\u57fa\u56e0\u8868\u9054\uff0c\u963b\u65b7\u5167\u6e90\u6027\u51dd\u8840\u9014\u5f91\u6fc0\u6d3b\uff0c\u5be6\u73fe\u7cbe\u6e96\u7684\u6297\u51dd\u8207\u6297\u8840\u6813\u4f5c\u7528\u3002\u4eba\u985e\u907a\u50b3\u5b78\u7814\u7a76\u8868\u660e\uff0cFXI\u6c34\u5e73\u5929\u7136\u504f\u4f4e\u7684\u4eba\u7fa4\u7f79\u60a3\u8840\u6813\u6027\u75be\u75c5\u6982\u7387\u8f03\u4f4e\uff0c\u4e14\u4e0d\u6703\u589e\u52a0\u81ea\u767c\u6027\u51fa\u8840\u98a8\u96aa\u3002\u56e0\u6b64\uff0cFXI\u6291\u5236\u5df2\u6210\u70ba\u7576\u524d\u6975\u5177\u524d\u666f\u7684\u6f5b\u5728\u6cbb\u7642\u624b\u6bb5\uff0c\u65e2\u80fd\u6709\u6548\u9810\u9632\u8840\u6813\u5f62\u6210\uff0c\u540c\u6642\u76f8\u8f03\u65bc\u73fe\u6709\u6297\u51dd\u7642\u6cd5\u5177\u6709\u66f4\u9ad8\u7684\u5b89\u5168\u6027\u3002<\/p>\n<p><b>\u95dc\u65bc\u745e\u535a\u751f\u7269\u53ca\u745e\u535a\u570b\u969b\u7814\u767c\u4e2d\u5fc3<\/b><\/p>\n<p>\u8607\u5dde\u745e\u535a\u751f\u7269\u6280\u8853\u80a1\u4efd\u6709\u9650\u516c\u53f8 (\u745e\u535a\u751f\u7269\uff0c06938.HK) \u662f\u4e00\u5bb6\u57fa\u65bc\u5c0f\u6838\u9178 (RNAi) \u6280\u8853\u3001\u81f4\u529b\u65bc\u958b\u767c\u5c0f\u6838\u9178\u985e\u85e5\u7269\u7684\u5275\u65b0\u578b\u81e8\u5e8a\u7814\u767c\u4f01\u696d\u3002\u6191\u501f\u5176\u5275\u65b0\u7814\u767c\u80fd\u529b\u548c\u5168\u6280\u8853\u93c8\u6574\u5408\u7684\u6280\u8853\u5e73\u53f0\uff0c\u745e\u535a\u751f\u7269\u5efa\u7acb\u4e86\u5f37\u5927\u7684\u7522\u54c1\u7ba1\u7dda\uff0c\u65e8\u5728\u70ba\u89e3\u6c7a\u56b4\u91cd\u75be\u75c5\u7684\u672a\u88ab\u6eff\u8db3\u81e8\u5e8a\u91ab\u7642\u9700\u6c42\u505a\u51fa\u8ca2\u737b\u3002\u66f4\u591a\u4fe1\u606f\u8acb\u8a2a\u554f<a href=\"https:\/\/www.ribolia.com\/\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">www.ribolia.com<\/a>\u3002<\/p>\n<p>\u745e\u535a\u570b\u969b\u7814\u767c\u4e2d\u5fc3 (Ribocure Pharmaceuticals AB) \u4f5c\u70ba\u745e\u535a\u751f\u7269\u7684\u5b50\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u633d\u6551\u751f\u547d\u7684\u5be1\u6838\u7518\u9178\u7642\u6cd5\u7684\u5168\u7403\u7814\u767c\uff0c\u805a\u7126\u8cc7\u7522\u548c\u7ba1\u7dda\u4ee5\u53ca\u65b0\u9776\u9ede\u7684\u958b\u767c\uff0c\u69cb\u5efa\u81e8\u5e8a\u8a66\u9a57\u548csiRNA\u85e5\u7269\u958b\u767c\u7684\u5275\u65b0\u80fd\u529b\uff0c\u4ee5\u89e3\u6c7a\u5168\u7403\u7bc4\u570d\u5167\u7684\u672a\u88ab\u6eff\u8db3\u91ab\u7642\u9700\u6c42\u3002\u66f4\u591a\u4fe1\u606f\u8acb\u8a2a\u554f<a href=\"https:\/\/www.ribocure.com\/\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">www.ribocure.com<\/a>\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4e2d\u570b\u4e0a\u6d77\u548c\u745e\u5178\u9ed8\u6069\u9054\u723e2026&#8230;<\/p>\n","protected":false},"author":16,"featured_media":455603,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-455602","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u745e\u535a\u751f\u7269\u62ab\u9732\u5168\u7403\u9996\u500b\u9776\u5411FXI\u7684siRNA\u85e5\u7269vortosiran\u7684IIa\u671f\u81e8\u5e8a\u7a4d\u6975\u6578\u64da - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831<\/title>\n<meta name=\"description\" content=\"\u4e2d\u570b\u4e0a\u6d77\u548c\u745e\u5178\u9ed8\u6069\u9054\u723e2026\u5e747\u670822\u65e5 \/\u7f8e\u901a\u793e\/ -- \u8607\u5dde\u745e\u535a\u751f\u7269\u6280\u8853\u80a1\u4efd\u6709\u9650\u516c\u53f8 (06938.HK) \u53ca\u5176\u5b50\u516c\u53f8Ribocure Pharmaceuticals\uff08\u5408\u7a31\u300c\u745e\u535a\u751f\u7269\u300d\uff09\u4eca\u65e5\u5728\u4e0a\u6d77\u8209\u884c\u7684\u5927\u570b\u65b0\u85e5\u5168\u7403\u6703\u8b70\uff08CPIC\uff09\u4e0a\uff0c\u9996\u6b21\u516c\u4f48\u5176\u9776\u5411\u51dd\u8840\u56e0\u5b50XI (FXI) \u7684siRNA\u5019\u9078\u85e5\u7269vortosiran (RBD4059) \u5728\u6b50\u6d32\u5b8c\u6210\u7684\u4e00\u9805 \u91dd\u5c0d\u6162\u6027\u51a0\u72c0\u52d5\u8108\u75be\u75c5\uff08CAD\uff09\u60a3\u8005\u7684IIa\u671f\u81e8\u5e8a\u7814\u7a76\u7684\u7a4d\u6975\u7d50\u679c\u3002   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content=\"\u745e\u535a\u751f\u7269\u62ab\u9732\u5168\u7403\u9996\u500b\u9776\u5411FXI\u7684siRNA\u85e5\u7269vortosiran\u7684IIa\u671f\u81e8\u5e8a\u7a4d\u6975\u6578\u64da - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u4e2d\u570b\u4e0a\u6d77\u548c\u745e\u5178\u9ed8\u6069\u9054\u723e2026\u5e747\u670822\u65e5 \/\u7f8e\u901a\u793e\/ -- \u8607\u5dde\u745e\u535a\u751f\u7269\u6280\u8853\u80a1\u4efd\u6709\u9650\u516c\u53f8 (06938.HK) \u53ca\u5176\u5b50\u516c\u53f8Ribocure Pharmaceuticals\uff08\u5408\u7a31\u300c\u745e\u535a\u751f\u7269\u300d\uff09\u4eca\u65e5\u5728\u4e0a\u6d77\u8209\u884c\u7684\u5927\u570b\u65b0\u85e5\u5168\u7403\u6703\u8b70\uff08CPIC\uff09\u4e0a\uff0c\u9996\u6b21\u516c\u4f48\u5176\u9776\u5411\u51dd\u8840\u56e0\u5b50XI (FXI) \u7684siRNA\u5019\u9078\u85e5\u7269vortosiran (RBD4059) \u5728\u6b50\u6d32\u5b8c\u6210\u7684\u4e00\u9805 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