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\u4e0a\u6d77<\/span>2026\u5e746\u670822\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u79d1\u6fdf\u85e5\u696d\uff08\u80a1\u7968\u4ee3\u78bc\uff1a2171.HK\uff09\uff0c\u4e00\u5bb6\u5c08\u6ce8\u65bc\u958b\u767c\u5275\u65b0CAR-T\u7d30\u80de\u7642\u6cd5\u7684\u751f\u7269\u5236\u85e5\u516c\u53f8\u5ba3\u5e03\uff0c\u4eca\u65e5\u5df2\u6536\u5230\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u901a\u77e5\uff0c\u6279\u51c6\u5176\u81ea\u4e3b\u7814\u767c\u7684Claudin18.2\u81ea\u9ad4\u4eba\u6e90\u5316CAR-T\u7d30\u80de\u6cbb\u7642\u7522\u54c1\u2014\u2014\u6137\u529b\u7f8e\u00ae<\/sup>\uff08\u8212\u745e\u57fa\u5967\u4f96\u8cfd\u6ce8\u5c04\u6db2\uff09\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff0c\u7528\u65bc\u6cbb\u7642Claudin18.2\u967d\u6027\u3001\u4eba\u8868\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u9ad42\uff08HER2\uff09\u9670\u6027\uff0c\u81f3\u5c11\u4e8c\u7dda\u6cbb\u7642\u5931\u6557\u7684\u665a\u671f\u80c3\/\u98df\u7ba1\u80c3\u7d50\u5408\u90e8\u817a\u764c\u3002\u6137\u529b\u7f8e\u00ae<\/sup>\u662f\u5168\u7403\u9996\u6b3e\u7372\u6279\u7528\u65bc\u5be6\u9ad4\u7624\u6cbb\u7642\u7684CAR-T\u7d30\u80de\u6cbb\u7642\u7522\u54c1\u3002<\/p>\n

\n<\/p><\/div>\n

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\u95dc\u65bc\u6137\u529b\u7f8e<\/b>\u00ae<\/sup><\/b><\/p>\n

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\u53c3\u8003\u6587\u737b<\/b><\/span><\/p>\n<\/td>\n<\/tr>\n

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[1]<\/sup>\u00a0World Health Organization (WHO). International Agency for Research on Cancer. Cancers Fact Sheet (Globocan 2022). Cancer Today (who.int). Last accessed 22-May-2024.<\/span><\/p>\n<\/td>\n<\/tr>\n

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[2]<\/sup> International Agency for Research on Cancer. (2021). Stomach fact sheet. IARC Global Cancer Observatory.<\/span><\/p>\n<\/td>\n<\/tr>\n

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[3]<\/sup>\u00a0Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115-32.<\/span><\/p>\n<\/td>\n<\/tr>\n

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[4]\u00a0<\/sup>B. Han, R. Zheng, H. Zeng, S. Wang, K. Sun, R. Chen, et al. Cancer incidence and mortality in China, 2022. J Natl Cancer Center, 4 (1) (2024), pp. 47-53.<\/span><\/p>\n<\/td>\n<\/tr>\n

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[5]<\/sup>\u00a0Zhao, Lulu, et al. “Changing Landscape in Stage, Treatment and Survival of Gastric Cancer in China 1998\u20132022: Insights of 40,158 Patients from the National Gastric Cancer Cohort.” Cancer Letters, vol. 642, 2026, p. 218261. DOI: 10.1016\/j.canlet.2026.218261.<\/span><\/p>\n<\/td>\n<\/tr>\n

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[6]<\/sup> Qi C, Liu C, Peng Z, Zhang Y, Wei J, Qiu W, Zhang X, Pan H, Niu Z, Qiu M, Qin Y, Fang W, Ye F, Li N, Liu T, Liu A, Zhang X, Hu C, Zhang J, Cui J, Lin X, Wang S, Zhang J, Lin T, Qu X, Yuan X, Gong J, Li J, Gao W, Gai L, Wang Y, Yuan D, Li Z, Shen L. Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician’s choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial. Lancet. 2025 Jun 7;405(10494):2049-2060. doi: 10.1016\/S0140-6736(25)00860-8. Epub 2025 May 31. PMID: 40460847.<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n

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\u4e0a\u767c\u5e03\u7684\u5176\u4ed6\u516c\u544a\u548c\u5831\u544a\u4e2d\u300c\u4e3b\u8981\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u300d\u6a19\u984c\u4e0b\u7684\u8a73\u7d30\u5167\u5bb9\u3002\u5c0d\u65bc\u672c\u65b0\u805e\u7a3f\u4e2d\u7684\u4efb\u4f55\u9810\u6e2c\u3001\u76ee\u6a19\u3001\u4f30\u8a08\u6216\u9810\u6e2c\u7684\u5be6\u73fe\u6216\u5408\u7406\u6027\uff0c\u6211\u5011\u4e0d\u4f5c\u4efb\u4f55\u9673\u8ff0\u6216\u4fdd\u8b49\uff0c\u4e5f\u4e0d\u61c9\u4f9d\u8cf4\u9019\u4e9b\u9810\u6e2c\u3002 \u53c3\u8003\u6587\u737b \u00a0World Health Organization (WHO). International Agency for Research on Cancer. Cancers Fact Sheet (Globocan 2022). Cancer Today (who.int). Last accessed 22-May-2024. International Agency for Research on Cancer. (2021). Stomach fact sheet. IARC Global Cancer Observatory. \u00a0Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115-32. \u00a0B. Han, R. Zheng, H. Zeng, S. Wang, K. Sun, R. Chen, et al. Cancer incidence and mortality in China, 2022. J Natl Cancer Center, 4 (1) (2024), pp. 47-53. \u00a0Zhao, Lulu, et al. "Changing Landscape in Stage, Treatment and Survival of Gastric Cancer in China 1998\u20132022: Insights of 40,158 Patients from the National Gastric Cancer Cohort." Cancer Letters, vol. 642, 2026, p. 218261. DOI: 10.1016\/j.canlet.2026.218261. Qi C, Liu C, Peng Z, Zhang Y, Wei J, Qiu W, Zhang X, Pan H, Niu Z, Qiu M, Qin Y, Fang W, Ye F, Li N, Liu T, Liu A, Zhang X, Hu C, Zhang J, Cui J, Lin X, Wang S, Zhang J, Lin T, Qu X, Yuan X, Gong J, Li J, Gao W, Gai L, Wang Y, Yuan D, Li Z, Shen L. Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial. Lancet. 2025 Jun 7;405(10494):2049-2060. doi: 10.1016\/S0140-6736(25)00860-8. Epub 2025 May 31. PMID: 40460847. \u806f\u7e6b\u79d1\u6fdf\u85e5\u696d\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u516c\u53f8\u7db2\u7ad9\uff1ahttps:\/\/www.carsgen.com\/\u516c\u5171\u95dc\u7cfb\uff1aPR@carsgen.com\u00a0\u6295\u8cc7\u8005\u95dc\u7cfb\uff1aIR@carsgen.com\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=447321\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u79d1\u6fdf\u85e5\u696d\u5168\u7403\u9996\u6b3e\u6cbb\u7642\u5be6\u9ad4\u7624\u7684CAR-T\u7d30\u80de\u6cbb\u7642\u7522\u54c1\u6137\u529b\u7f8e\u00ae\u7372\u6279\u4e0a\u5e02 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u4e0a\u6d772026\u5e746\u670822\u65e5 \/\u7f8e\u901a\u793e\/ -- 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\u4e0a\u767c\u5e03\u7684\u5176\u4ed6\u516c\u544a\u548c\u5831\u544a\u4e2d\u300c\u4e3b\u8981\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u300d\u6a19\u984c\u4e0b\u7684\u8a73\u7d30\u5167\u5bb9\u3002\u5c0d\u65bc\u672c\u65b0\u805e\u7a3f\u4e2d\u7684\u4efb\u4f55\u9810\u6e2c\u3001\u76ee\u6a19\u3001\u4f30\u8a08\u6216\u9810\u6e2c\u7684\u5be6\u73fe\u6216\u5408\u7406\u6027\uff0c\u6211\u5011\u4e0d\u4f5c\u4efb\u4f55\u9673\u8ff0\u6216\u4fdd\u8b49\uff0c\u4e5f\u4e0d\u61c9\u4f9d\u8cf4\u9019\u4e9b\u9810\u6e2c\u3002 \u53c3\u8003\u6587\u737b \u00a0World Health Organization (WHO). International Agency for Research on Cancer. Cancers Fact Sheet (Globocan 2022). Cancer Today (who.int). Last accessed 22-May-2024. International Agency for Research on Cancer. (2021). Stomach fact sheet. IARC Global Cancer Observatory. \u00a0Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115-32. \u00a0B. Han, R. Zheng, H. Zeng, S. Wang, K. Sun, R. Chen, et al. Cancer incidence and mortality in China, 2022. J Natl Cancer Center, 4 (1) (2024), pp. 47-53. \u00a0Zhao, Lulu, et al. "Changing Landscape in Stage, Treatment and Survival of Gastric Cancer in China 1998\u20132022: Insights of 40,158 Patients from the National Gastric Cancer Cohort." Cancer Letters, vol. 642, 2026, p. 218261. DOI: 10.1016\/j.canlet.2026.218261. Qi C, Liu C, Peng Z, Zhang Y, Wei J, Qiu W, Zhang X, Pan H, Niu Z, Qiu M, Qin Y, Fang W, Ye F, Li N, Liu T, Liu A, Zhang X, Hu C, Zhang J, Cui J, Lin X, Wang S, Zhang J, Lin T, Qu X, Yuan X, Gong J, Li J, Gao W, Gai L, Wang Y, Yuan D, Li Z, Shen L. Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial. Lancet. 2025 Jun 7;405(10494):2049-2060. doi: 10.1016\/S0140-6736(25)00860-8. Epub 2025 May 31. 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\u4e0a\u767c\u5e03\u7684\u5176\u4ed6\u516c\u544a\u548c\u5831\u544a\u4e2d\u300c\u4e3b\u8981\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u300d\u6a19\u984c\u4e0b\u7684\u8a73\u7d30\u5167\u5bb9\u3002\u5c0d\u65bc\u672c\u65b0\u805e\u7a3f\u4e2d\u7684\u4efb\u4f55\u9810\u6e2c\u3001\u76ee\u6a19\u3001\u4f30\u8a08\u6216\u9810\u6e2c\u7684\u5be6\u73fe\u6216\u5408\u7406\u6027\uff0c\u6211\u5011\u4e0d\u4f5c\u4efb\u4f55\u9673\u8ff0\u6216\u4fdd\u8b49\uff0c\u4e5f\u4e0d\u61c9\u4f9d\u8cf4\u9019\u4e9b\u9810\u6e2c\u3002 \u53c3\u8003\u6587\u737b \u00a0World Health Organization (WHO). 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Qi C, Liu C, Peng Z, Zhang Y, Wei J, Qiu W, Zhang X, Pan H, Niu Z, Qiu M, Qin Y, Fang W, Ye F, Li N, Liu T, Liu A, Zhang X, Hu C, Zhang J, Cui J, Lin X, Wang S, Zhang J, Lin T, Qu X, Yuan X, Gong J, Li J, Gao W, Gai L, Wang Y, Yuan D, Li Z, Shen L. Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial. Lancet. 2025 Jun 7;405(10494):2049-2060. doi: 10.1016\\\/S0140-6736(25)00860-8. Epub 2025 May 31. 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\u4e0a\u767c\u5e03\u7684\u5176\u4ed6\u516c\u544a\u548c\u5831\u544a\u4e2d\u300c\u4e3b\u8981\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u300d\u6a19\u984c\u4e0b\u7684\u8a73\u7d30\u5167\u5bb9\u3002\u5c0d\u65bc\u672c\u65b0\u805e\u7a3f\u4e2d\u7684\u4efb\u4f55\u9810\u6e2c\u3001\u76ee\u6a19\u3001\u4f30\u8a08\u6216\u9810\u6e2c\u7684\u5be6\u73fe\u6216\u5408\u7406\u6027\uff0c\u6211\u5011\u4e0d\u4f5c\u4efb\u4f55\u9673\u8ff0\u6216\u4fdd\u8b49\uff0c\u4e5f\u4e0d\u61c9\u4f9d\u8cf4\u9019\u4e9b\u9810\u6e2c\u3002 \u53c3\u8003\u6587\u737b \u00a0World Health Organization (WHO). International Agency for Research on Cancer. Cancers Fact Sheet (Globocan 2022). Cancer Today (who.int). Last accessed 22-May-2024. International Agency for Research on Cancer. (2021). Stomach fact sheet. IARC Global Cancer Observatory. \u00a0Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115-32. \u00a0B. Han, R. Zheng, H. Zeng, S. Wang, K. Sun, R. Chen, et al. Cancer incidence and mortality in China, 2022. J Natl Cancer Center, 4 (1) (2024), pp. 47-53. \u00a0Zhao, Lulu, et al. \"Changing Landscape in Stage, Treatment and Survival of Gastric Cancer in China 1998\u20132022: Insights of 40,158 Patients from the National Gastric Cancer Cohort.\" Cancer Letters, vol. 642, 2026, p. 218261. DOI: 10.1016\/j.canlet.2026.218261. Qi C, Liu C, Peng Z, Zhang Y, Wei J, Qiu W, Zhang X, Pan H, Niu Z, Qiu M, Qin Y, Fang W, Ye F, Li N, Liu T, Liu A, Zhang X, Hu C, Zhang J, Cui J, Lin X, Wang S, Zhang J, Lin T, Qu X, Yuan X, Gong J, Li J, Gao W, Gai L, Wang Y, Yuan D, Li Z, Shen L. Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial. Lancet. 2025 Jun 7;405(10494):2049-2060. doi: 10.1016\/S0140-6736(25)00860-8. Epub 2025 May 31. PMID: 40460847. \u806f\u7e6b\u79d1\u6fdf\u85e5\u696d\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u516c\u53f8\u7db2\u7ad9\uff1ahttps:\/\/www.carsgen.com\/\u516c\u5171\u95dc\u7cfb\uff1aPR@carsgen.com\u00a0\u6295\u8cc7\u8005\u95dc\u7cfb\uff1aIR@carsgen.com","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pingtungtimes.com.tw\/?p=447321","og_locale":"zh_TW","og_type":"article","og_title":"\u79d1\u6fdf\u85e5\u696d\u5168\u7403\u9996\u6b3e\u6cbb\u7642\u5be6\u9ad4\u7624\u7684CAR-T\u7d30\u80de\u6cbb\u7642\u7522\u54c1\u6137\u529b\u7f8e\u00ae\u7372\u6279\u4e0a\u5e02 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","og_description":"\u4e0a\u6d772026\u5e746\u670822\u65e5 \/\u7f8e\u901a\u793e\/ -- 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\u4e0a\u767c\u5e03\u7684\u5176\u4ed6\u516c\u544a\u548c\u5831\u544a\u4e2d\u300c\u4e3b\u8981\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u300d\u6a19\u984c\u4e0b\u7684\u8a73\u7d30\u5167\u5bb9\u3002\u5c0d\u65bc\u672c\u65b0\u805e\u7a3f\u4e2d\u7684\u4efb\u4f55\u9810\u6e2c\u3001\u76ee\u6a19\u3001\u4f30\u8a08\u6216\u9810\u6e2c\u7684\u5be6\u73fe\u6216\u5408\u7406\u6027\uff0c\u6211\u5011\u4e0d\u4f5c\u4efb\u4f55\u9673\u8ff0\u6216\u4fdd\u8b49\uff0c\u4e5f\u4e0d\u61c9\u4f9d\u8cf4\u9019\u4e9b\u9810\u6e2c\u3002 \u53c3\u8003\u6587\u737b \u00a0World Health Organization (WHO). 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Qi C, Liu C, Peng Z, Zhang Y, Wei J, Qiu W, Zhang X, Pan H, Niu Z, Qiu M, Qin Y, Fang W, Ye F, Li N, Liu T, Liu A, Zhang X, Hu C, Zhang J, Cui J, Lin X, Wang S, Zhang J, Lin T, Qu X, Yuan X, Gong J, Li J, Gao W, Gai L, Wang Y, Yuan D, Li Z, Shen L. Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial. Lancet. 2025 Jun 7;405(10494):2049-2060. doi: 10.1016\/S0140-6736(25)00860-8. Epub 2025 May 31. 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\u4e0a\u767c\u5e03\u7684\u5176\u4ed6\u516c\u544a\u548c\u5831\u544a\u4e2d\u300c\u4e3b\u8981\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u300d\u6a19\u984c\u4e0b\u7684\u8a73\u7d30\u5167\u5bb9\u3002\u5c0d\u65bc\u672c\u65b0\u805e\u7a3f\u4e2d\u7684\u4efb\u4f55\u9810\u6e2c\u3001\u76ee\u6a19\u3001\u4f30\u8a08\u6216\u9810\u6e2c\u7684\u5be6\u73fe\u6216\u5408\u7406\u6027\uff0c\u6211\u5011\u4e0d\u4f5c\u4efb\u4f55\u9673\u8ff0\u6216\u4fdd\u8b49\uff0c\u4e5f\u4e0d\u61c9\u4f9d\u8cf4\u9019\u4e9b\u9810\u6e2c\u3002 \u53c3\u8003\u6587\u737b \u00a0World Health Organization (WHO). 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Qi C, Liu C, Peng Z, Zhang Y, Wei J, Qiu W, Zhang X, Pan H, Niu Z, Qiu M, Qin Y, Fang W, Ye F, Li N, Liu T, Liu A, Zhang X, Hu C, Zhang J, Cui J, Lin X, Wang S, Zhang J, Lin T, Qu X, Yuan X, Gong J, Li J, Gao W, Gai L, Wang Y, Yuan D, Li Z, Shen L. Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial. Lancet. 2025 Jun 7;405(10494):2049-2060. doi: 10.1016\/S0140-6736(25)00860-8. Epub 2025 May 31. 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