{"id":441481,"date":"2026-06-02T20:59:00","date_gmt":"2026-06-02T12:59:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=441481"},"modified":"2026-06-02T20:59:00","modified_gmt":"2026-06-02T12:59:00","slug":"%e9%9b%b2%e9%a0%82%e6%96%b0%e8%80%80%e5%ae%a3%e4%bd%88%e5%b0%b1%e5%b8%8c%e5%b8%83%e6%9b%bf%e5%b0%bc%ef%bc%88ever001%ef%bc%89%e9%81%94%e6%88%90%e7%8d%a8%e5%ae%b6%e6%8e%88%e6%ac%8a%e8%a8%b1%e5%8f%af","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=441481","title":{"rendered":"\u96f2\u9802\u65b0\u8000\u5ba3\u4f48\u5c31\u5e0c\u5e03\u66ff\u5c3c\uff08EVER001\uff09\u9054\u6210\u7368\u5bb6\u6388\u6b0a\u8a31\u53ef\u8207\u5408\u4f5c\u5354\u8b70"},"content":{"rendered":"<div>\n<ul type=\"disc\">\n<li>\u96f2\u9802\u65b0\u8000\u8207Travere Therapeutics\u9054\u6210\u7368\u5bb6\u6388\u6b0a\u8a31\u53ef\u8207\u5408\u4f5c\u5354\u8b70\uff0c\u6388\u4e88\u5176EVER001\uff08\u5e0c\u5e03\u66ff\u5c3c\uff0ccivorebrutinib\uff09\u9664\u5927\u4e2d\u83ef\u5340\u53ca\u90e8\u5206\u6771\u5357\u4e9e\u570b\u5bb6\u4ee5\u5916\u5340\u57df\u7684\u7368\u5bb6\u958b\u767c\u53ca\u5546\u696d\u5316\u6b0a\u76ca\u3002<\/li>\n<li>\u6839\u64da\u5354\u8b70\uff0c\u96f2\u9802\u65b0\u8000\u5c07\u7372\u5f971.125\u5104\u7f8e\u5143\u7684\u9996\u4ed8\u6b3e\uff0c\u4e26\u6709\u8cc7\u683c\u5728\u6700\u591a\u4e94\u500b\u9069\u61c9\u75c7\u4e0a\u7372\u5f97\u9ad8\u905410.3\u5104\u7f8e\u5143\u7684\u958b\u767c\u3001\u8a3b\u518a\u53ca\u5546\u696d\u5316\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u6b64\u5916\uff0c\u516c\u53f8\u9084\u5c07\u57fa\u65bcEVER001\u7684\u672a\u4f86\u5e74\u5ea6\u6de8\u92b7\u552e\u984d\uff0c\u7372\u5f97\u5f9e\u9ad8\u500b\u4f4d\u6578\u81f3\u96d9\u4f4d\u6578\u767e\u5206\u6bd4\u7684\u5206\u7d1a\u7279\u8a31\u6b0a\u4f7f\u7528\u8cbb\u3002<\/li>\n<li>EVER001\u662f\u96f2\u9802\u65b0\u8000\u7684\u65b0\u4e00\u4ee3\u5171\u50f9\u53ef\u9006\u5e03\u9b6f\u9813\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5291\uff0c\u5177\u5099\u300c\u4e00\u500b\u53ef\u4ee5\u958b\u767c\u591a\u7a2e\u9069\u61c9\u75c7\u7684\u85e5\u7269\uff08pipeline-in-a-product\uff09\u300d\u7684\u958b\u767c\u6f5b\u529b\uff0c\u6709\u671b\u70ba\u5168\u7403\u903e1000\u842c\u60a3\u6709\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\uff08PMN\uff09\u3001IgA\u814e\u75c5\u3001\u5fae\u5c0f\u75c5\u8b8a\u6027\u814e\u75c5\uff08MCD\uff09\u3001\u5c40\u7076\u7bc0\u6bb5\u6027\u814e\u5c0f\u7403\u786c\u5316\uff08FSGS\uff09\u548c\u72fc\u7621\u6027\u814e\u708e\u7b49\u75be\u75c5\u7684\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u6cbb\u7642\u9078\u64c7\uff0c\u4e26\u5c55\u73fe\u51fa\u6f5b\u5728\u7684\u5ee3\u6cdb\u61c9\u7528\u50f9\u503c\u3002<\/li>\n<li>\u6b64\u6b21\u5408\u4f5c\u5c07\u52a0\u901fEVER001\u5728\u591a\u7a2e\u514d\u75ab\u4ecb\u5c0e\u7684\u814e\u81df\u75be\u75c5\u4e2d\u7684\u958b\u767c\u9032\u7a0b\u3002EVER001\u8a08\u5283\u5728PMN\u3001\u514d\u75ab\u4ecb\u5c0e\u7684FSGS\u53caMCD\u7b49\u9069\u61c9\u75c7\u4e2d\u958b\u5c55\u81e8\u5e8a\u7814\u7a76\uff0c\u4e26\u6709\u671b\u9032\u4e00\u6b65\u62d3\u5c55\u81f3\u66f4\u591a\u9069\u61c9\u75c7\u9818\u57df\u3002<\/li>\n<\/ul>\n<p><span class=\"legendSpanClass\">\u4e0a\u6d77<\/span><span class=\"legendSpanClass\">2026\u5e746\u67082\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u96f2\u9802\u65b0\u8000\uff08HKEX 1952.HK\uff0c\u4ee5\u4e0b\u7c21\u7a31\u300c\u516c\u53f8\u300d\uff09\uff0c\u4e00\u5bb6\u5c08\u6ce8\u65bc\u5275\u65b0\u85e5\u7814\u767c\u3001\u81e8\u5e8a\u958b\u767c\u3001\u88fd\u9020\u53ca\u5546\u696d\u5316\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\u516c\u53f8\u8207Travere Therapeutics, Inc.\uff08NASDAQ: TVTX\uff0c\u4ee5\u4e0b\u7c21\u7a31\u300cTravere Therapeutics\u300d\uff09\u9054\u6210\u7368\u5bb6\u6388\u6b0a\u8a31\u53ef\u8207\u5408\u4f5c\u5354\u8b70\u3002\u6839\u64da\u5354\u8b70\uff0cTravere Therapeutics\u5c07\u7372\u5f97EVER001\uff08\u5e0c\u5e03\u66ff\u5c3c\uff0ccivorebrutinib\uff09\u9664\u5927\u4e2d\u83ef\u5340\u53ca\u90e8\u5206\u6771\u5357\u4e9e\u570b\u5bb6\u4ee5\u5916\u5340\u57df\u7684\u7368\u5bb6\u958b\u767c\u53ca\u5546\u696d\u5316\u6b0a\u76ca\u3002\u6b64\u6b21\u5408\u4f5c\u5c07\u52a0\u901fEVER001\u7684\u5168\u7403\u81e8\u5e8a\u958b\u767c\u8207\u5546\u696d\u5316\u9032\u7a0b\uff0c\u70ba\u5168\u7403\u814e\u75c5\u60a3\u8005\u5e36\u4f86\u5275\u65b0\u6cbb\u7642\u9078\u64c7\u3002<\/p>\n<p>\u6839\u64da\u5354\u8b70\uff0c\u96f2\u9802\u65b0\u8000\u5c07\u7372\u5f971.125\u5104\u7f8e\u5143\u7684\u9996\u4ed8\u6b3e\uff0c\u4e26\u6709\u8cc7\u683c\u5728\u6700\u591a\u4e94\u500b\u9069\u61c9\u75c7\u4e0a\u7372\u5f97\u9ad8\u905410.3\u5104\u7f8e\u5143\u7684\u958b\u767c\u3001\u8a3b\u518a\u53ca\u5546\u696d\u5316\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u6b64\u5916\uff0c\u516c\u53f8\u9084\u5c07\u57fa\u65bcEVER001\u7684\u672a\u4f86\u5e74\u5ea6\u6de8\u92b7\u552e\u984d\uff0c\u7372\u5f97\u5f9e\u9ad8\u500b\u4f4d\u6578\u81f3\u96d9\u4f4d\u6578\u767e\u5206\u6bd4\u7684\u5206\u7d1a\u7279\u8a31\u6b0a\u4f7f\u7528\u8cbb\u3002\u8a72\u4ea4\u6613\u5c07\u5728\u6eff\u8db3\u7279\u5b9a\u4ea4\u5272\u689d\u4ef6\u53ca\u5b8c\u6210\u5fc5\u8981\u76e3\u7ba1\u7a0b\u5e8f\u5f8c\u5b8c\u6210\u4ea4\u5272\u3002<\/p>\n<p>EVER001\u662f\u96f2\u9802\u65b0\u8000\u7684\u65b0\u4e00\u4ee3\u5171\u50f9\u53ef\u9006\u5e03\u9b6f\u9813\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5291\uff0c\u5177\u5099\u300c\u4e00\u500b\u53ef\u4ee5\u958b\u767c\u591a\u7a2e\u9069\u61c9\u75c7\u7684\u85e5\u7269\uff08pipeline-in-a-product\uff09\u300d\u7684\u958b\u767c\u6f5b\u529b\u3002\u8207\u5171\u50f9\u4e0d\u53ef\u9006BTK\u6291\u5236\u5291\u76f8\u6bd4\uff0cEVER001\u4f5c\u70ba\u4e00\u6b3e\u6f5b\u5728\u7684\u540c\u985e\u6700\u4f73\u7522\u54c1\uff0c\u5728\u4fdd\u6301\u9ad8\u6d3b\u6027\u7684\u540c\u6642\u5177\u6709\u9ad8\u9078\u64c7\u6027\uff0c\u907f\u514d\u6301\u7e8c\u6291\u5236\u5e36\u4f86\u7684\u6bd2\u526f\u4f5c\u7528\u3002\u76ee\u524d\uff0c\u5168\u7403\u5c1a\u7121\u85e5\u7269\u7372\u6279\u7528\u65bc\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u6cbb\u7642\u3002\u73fe\u6709\u50b3\u7d71\u514d\u75ab\u6291\u5236\u5291\u6cbb\u7642\u6548\u679c\u5b58\u5728\u5c40\u9650\uff0c\u4e14\u90e8\u5206\u60a3\u8005\u5728\u505c\u85e5\u5f8c\u6613\u5fa9\u767c\uff0c\u540c\u6642\u4f34\u96a8\u4e00\u5b9a\u4e0d\u826f\u53cd\u61c9\uff0c\u81e8\u5e8a\u4ecd\u5b58\u5728\u672a\u6eff\u8db3\u7684\u6cbb\u7642\u9700\u6c42\u3002<\/p>\n<p>\u6b64\u524d\u516c\u4f48\u7528\u65bc\u6cbb\u7642\u4e2d\u570bPMN\u60a3\u8005\u76841b\/2a\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\u986f\u793a\uff0cEVER001\u5c55\u73fe\u51fa\u5feb\u901f\u3001\u6df1\u5ea6\u4e14\u6301\u4e45\u7684\u514d\u75ab\u5b78\u548c\u81e8\u5e8a\u7de9\u89e3\uff0c\u505c\u85e5\u5f8c\u4ecd\u6301\u7e8c\u7372\u76ca\uff0c\u5b89\u5168\u6027\u9ad8\uff0c\u8010\u53d7\u6027\u5f37\u3002\u9019\u4e9b\u7d50\u679c\u652f\u6301EVER001\u5177\u6709\u6cbb\u7642\u4ee5\u86cb\u767d\u5c3f\u70ba\u7279\u5fb5\u7684\u81ea\u8eab\u514d\u75ab\u6027\u814e\u5c0f\u7403\u75be\u75c5\u7684\u6f5b\u529b\u3002<\/p>\n<p>EVER001\u5177\u5099\u5728\u591a\u7a2e\u514d\u75ab\u4ecb\u5c0e\u6027\u814e\u5c0f\u7403\u75be\u75c5\u4e2d\u7684\u958b\u767c\u6f5b\u529b\uff0c\u5305\u62ecPMN\u3001IgA\u814e\u75c5\u3001MCD\u3001FSGS\u53ca\u72fc\u7621\u6027\u814e\u708e\u7b49\u3002\u9019\u985e\u75be\u75c5\u5747\u8207\u7570\u5e38\u514d\u75ab\u53cd\u61c9\u5f15\u767c\u7684\u814e\u5c0f\u7403\u640d\u50b7\u76f8\u95dc\uff0c\u53ef\u5c0e\u81f4\u86cb\u767d\u5c3f\u548c\u814e\u529f\u80fd\u4e0b\u964d\uff0c\u56b4\u91cd\u6642\u751a\u81f3\u53ef\u80fd\u767c\u5c55\u81f3\u7d42\u672b\u671f\u814e\u75c5\uff0c\u9700\u8981\u900f\u6790\u6216\u814e\u79fb\u690d\u6cbb\u7642\u3002EVER001\u6709\u671b\u70ba\u5168\u7403\u903e1000\u842c\u540d\u76f8\u95dc\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u76ee\u524d\uff0cEVER001\u8a08\u5283\u5728PMN\u3001\u514d\u75ab\u4ecb\u5c0e\u7684FSGS\u53caMCD\u7b49\u9069\u61c9\u75c7\u4e2d\u958b\u5c55\u81e8\u5e8a\u7814\u7a76\uff0c\u4e26\u6709\u671b\u9032\u4e00\u6b65\u62d3\u5c55\u81f3\u66f4\u591a\u9069\u61c9\u75c7\u9818\u57df\u3002<\/p>\n<p><b>\u96f2\u9802\u65b0\u8000\u8463\u4e8b\u6703\u4e3b\u5e2d\u5433\u4ee5\u82b3\u8868\u793a<\/b>\uff1a\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u8207Travere Therapeutics\u9054\u6210\u6b64\u6b21\u5408\u4f5c\u3002\u9019\u4e00\u5408\u4f5c\u5c07\u52a0\u901fEVER001\u7684\u5168\u7403\u958b\u767c\u8207\u5546\u696d\u5316\u9032\u7a0b\uff0c\u9032\u4e00\u6b65\u91cb\u653e\u5176\u5728\u81ea\u8eab\u514d\u75ab\u6027\u814e\u81df\u75be\u75c5\u9818\u57df\u7684\u81e8\u5e8a\u6f5b\u529b\u8207\u5546\u696d\u50f9\u503c\uff0c\u70ba\u5168\u7403\u60a3\u8005\u5e36\u4f86\u66f4\u591a\u5275\u65b0\u6cbb\u7642\u9078\u64c7\u3002<\/p>\n<p>\u4f5c\u70ba\u6f5b\u5728\u540c\u985e\u6700\u4f73\u5275\u65b0\u85e5\u7269\uff0cEVER001\u5df2\u5728\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u7b49\u81ea\u8eab\u514d\u75ab\u6027\u814e\u81df\u75be\u75c5\u6cbb\u7642\u4e2d\u5c55\u73fe\u51fa\u7a4d\u6975\u6f5b\u529b\u3002\u6191\u501f\u5176\u5dee\u7570\u5316\u4f5c\u7528\u6a5f\u5236\uff0cEVER001\u5177\u5099\u62d3\u5c55\u81f3\u591a\u7a2e\u81ea\u8eab\u514d\u75ab\u6027\u814e\u81df\u75be\u75c5\u7684\u6f5b\u529b\uff0c\u6301\u7e8c\u91cb\u653e\u5176\u81e8\u5e8a\u958b\u767c\u6f5b\u529b\u3002<\/p>\n<p>\u516c\u53f8\u59cb\u7d42\u5805\u6301&#8217;BD\u5408\u4f5c+\u81ea\u4e3b\u7814\u767c&#8217;\u96d9\u8f2a\u9a45\u52d5\u6230\u7565\uff0c\u6301\u7e8c\u63a8\u9032\u6230\u7565\u6027\u696d\u52d9\u62d3\u5c55\u8207\u81ea\u4e3b\u7814\u767c\uff0c\u4e0d\u65b7\u5b8c\u5584\u5168\u7403\u7814\u767c\u9ad4\u7cfb\u5efa\u8a2d\uff0c\u6301\u7e8c\u63d0\u5347\u5728\u5168\u7403\u5275\u65b0\u85e5\u9818\u57df\u7684\u7d9c\u5408\u7af6\u722d\u529b\u3002Travere Therapeutics\u5728\u7f8e\u570b\u5df2\u6709\u7372\u6279\u7684\u814e\u79d1\u7522\u54c1\uff0c\u5728\u814e\u75c5\u85e5\u7269\u958b\u767c\u3001\u8a3b\u518a\u53ca\u5546\u696d\u5316\u65b9\u9762\u7a4d\u7d2f\u4e86\u8c50\u5bcc\u7d93\u9a57\u8207\u6210\u719f\u80fd\u529b\u3002\u96d9\u65b9\u5c07\u5145\u5206\u767c\u63ee\u5404\u81ea\u512a\u52e2\uff0c\u5171\u540c\u63a8\u9032EVER001\u5728\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u3001\u514d\u75ab\u4ecb\u5c0e\u7684\u5c40\u7076\u7bc0\u6bb5\u6027\u814e\u5c0f\u7403\u786c\u5316\u53ca\u5fae\u5c0f\u75c5\u8b8a\u6027\u814e\u75c5\u4e0a\u7684\u5168\u7403\u81e8\u5e8a\u958b\u767c\uff0c\u70ba\u5168\u7403\u60a3\u8005\u5e36\u4f86\u66f4\u591a\u7a81\u7834\u6027\u6cbb\u7642\u9078\u64c7\u3002\u300d<\/p>\n<p><b>Travere Therapeutics\u7e3d\u88c1\u517c\u9996\u5e2d\u57f7\u884c\u5b98Eric Dube\u535a\u58eb\u8868\u793a<\/b>\uff1a\u300cEVER001\u662f\u516c\u53f8\u7f55\u898b\u814e\u75c5\u7ba1\u7dda\u7684\u91cd\u8981\u6230\u7565\u6027\u88dc\u5145\uff0c\u4e26\u5177\u6709\u986f\u8457\u7684\u5354\u540c\u50f9\u503c\uff0c\u6709\u671b\u6210\u70ba\u8986\u84cb\u591a\u7a2e\u514d\u75ab\u4ecb\u5c0e\u7f55\u898b\u814e\u75c5\u7684\u540c\u985e\u6700\u4f73\u7642\u6cd5\u3002\u7f55\u898b\u814e\u75c5\u60a3\u8005\u76ee\u524d\u4ecd\u9762\u81e8\u5de8\u5927\u7684\u672a\u6eff\u8db3\u81e8\u5e8a\u9700\u6c42\u3002\u6211\u5011\u8a8d\u70ba\uff0c\u5728IgA\u814e\u75c5\u548cFSGS\u9818\u57df\u5df2\u53d6\u5f97\u7684\u968e\u6bb5\u6027\u9032\u5c55\u50c5\u662f\u9019\u4e00\u6cbb\u7642\u9818\u57df\u6f5b\u529b\u91cb\u653e\u7684\u958b\u59cb\u3002Travere Therapeutics\u81f4\u529b\u65bc\u6301\u7e8c\u63a8\u52d5\u8a72\u9818\u57df\u7684\u91cd\u8981\u5275\u65b0\u8207\u7a81\u7834\uff0c\u6191\u501f\u5728\u7f55\u898b\u814e\u75c5\u9818\u57df\u7a4d\u7d2f\u7684\u6df1\u539a\u5c08\u696d\u7d93\u9a57\u3001\u6210\u719f\u7684\u7814\u767c\u8207\u5546\u696d\u5316\u80fd\u529b\uff0c\u4ee5\u53ca\u5c0d\u60a3\u8005\u7684\u6301\u7e8c\u627f\u8afe\uff0c\u6211\u5011\u5c07\u4e0d\u65b7\u63a8\u52d5\u5275\u65b0\uff0c\u70ba\u60a3\u8005\u5e36\u4f86\u66f4\u591a\u7a81\u7834\u6027\u6cbb\u7642\u9078\u64c7\u3002<\/p>\n<p>\u4f5c\u70ba\u4e00\u6b3e\u5177\u6709\u5dee\u7570\u5316\u512a\u52e2\u7684\u53e3\u670d\u53ef\u9006BTK\u6291\u5236\u5291\uff0cEVER001\u5728\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u4e2d\u5df2\u5c55\u73fe\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u6982\u5ff5\u9a57\u8b49\u6578\u64da\uff0c\u5176\u4f5c\u7528\u6a5f\u5236\u53ef\u8986\u84cb\u514d\u75ab\u4ecb\u5c0e\u7684\u5c40\u7076\u7bc0\u6bb5\u6027\u814e\u5c0f\u7403\u786c\u5316\u3001\u5fae\u5c0f\u75c5\u8b8a\u814e\u75c5\u7b49\u66f4\u591a\u75be\u75c5\u9818\u57df\u3002\u6211\u5011\u76f8\u4fe1\uff0cEVER001\u5c07\u70ba\u7f55\u898b\u814e\u75c5\u60a3\u8005\u5e36\u4f86\u66f4\u5177\u91cd\u8981\u610f\u7fa9\u7684\u6cbb\u7642\u7a81\u7834\uff0c\u9032\u4e00\u6b65\u63a8\u52d5\u8a72\u9818\u57df\u6cbb\u7642\u683c\u5c40\u7684\u91cd\u5851\u3002\u300d<\/p>\n<p>\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u70ba\u6210\u4eba\u814e\u75c5\u7d9c\u5408\u5f81\u5e38\u898b\u7684\u75c5\u7406\u985e\u578b\uff0c\u5728\u4e2d\u570b\u7684\u60a3\u75c5\u7387\u5448\u9010\u5e74\u5347\u9ad8\u7684\u8da8\u52e2\uff0c\u662f\u767c\u75c5\u7387\u50c5\u6b21\u65bcIgA\u814e\u75c5\u7684\u539f\u767c\u6027\u814e\u5c0f\u7403\u814e\u708e<sup>1<\/sup>\u3002\u76ee\u524d\u6211\u570b\u7d04\u6709200\u842c\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u60a3\u8005\u3002\u8d85\u904e1\/3\u7684\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u60a3\u8005\u6700\u7d42\u5c07\u9032\u5c55\u70ba\u7d42\u672b\u671f\u814e\u75c5\uff0c\u5168\u7403\u4e9f\u9700\u7814\u767c\u80fd\u63d0\u9ad8\u6cbb\u7642\u7de9\u89e3\u7387\u3001\u964d\u4f4e\u9ad8\u5fa9\u767c\u7387\u3001\u6e1b\u5c11\u6162\u6027\u814e\u6bd2\u6027\u98a8\u96aa\u7684\u6cbb\u7642\u85e5\u7269\u3002\u672a\u4f86\uff0c\u96f2\u9802\u65b0\u8000\u5c07\u651c\u624b\u5408\u4f5c\u5925\u4f34\u52a0\u901f\u63a8\u9032EVER001\u7684\u5168\u7403\u958b\u767c\u8207\u50f9\u503c\u8f49\u5316\uff0c\u4e26\u5728\u5176\u4ed6\u9069\u61c9\u75c7\u9818\u57df\u5171\u540c\u63a8\u52d5\u5f8c\u7e8c\u7814\u767c\u3002\u516c\u53f8\u5c07\u6301\u7e8c\u63d0\u5347\u5728\u5168\u7403\u5275\u65b0\u85e5\u9818\u57df\u7684\u7d9c\u5408\u7af6\u722d\u529b\uff0c\u70ba\u4e2d\u570b\u53ca\u5168\u7403\u60a3\u8005\u5e36\u4f86\u66f4\u591a\u7a81\u7834\u6027\u6cbb\u7642\u65b9\u6848\u3002<\/p>\n<p>EVER001\u7531\u8607\u5dde\u4fe1\u8afe\u7dad\u91ab\u85e5\u81ea\u4e3b\u7814\u767c\uff0c\u4e26\u65bc2021\u5e749\u6708\u8207\u4e2d\u570b\u6297\u9ad4\uff083681.HK\uff09\u5171\u540c\u6388\u4e88\u96f2\u9802\u65b0\u8000\u5728\u5168\u7403\u7bc4\u570d\u5167\u814e\u81df\u75be\u75c5\u9818\u57df\u958b\u767c\u548c\u5546\u696d\u5316\u7684\u6b0a\u5229\u3002<\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><i>\u53c3\u8003\u6587\u737b\uff1a<\/i><br \/><i>1. \u5229\u59a5\u6614\u55ae\u6297\u5728\u819c\u6027\u814e\u75c5\u4e2d\u61c9\u7528\u7684\u5c08\u5bb6\u5171\u8b58\uff0c\u4e2d\u83ef\u5167\u79d1\u96dc\u8a8c2022\u5e743\u6708\u7b2c61\u5377\u7b2c3\u671f\u3002<\/i><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p><b>\u95dc\u65bcEVER001\uff08\u5e0c\u5e03\u66ff\u5c3c\uff09<\/b><br \/>EVER001\u81a0\u56ca\uff08\u53c8\u540d\uff1aXNW1011\uff09\u662f\u4e00\u6b3e\u65b0\u4e00\u4ee3\u5171\u50f9\u53ef\u9006\u7684\u5e03\u9b6f\u9813\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5291\uff0c\u7531\u8607\u5dde\u4fe1\u8afe\u7dad\u91ab\u85e5\u81ea\u4e3b\u7814\u767c\uff0c\u4e26\u65bc2021\u5e749\u6708\u8207\u4e2d\u570b\u6297\u9ad4\uff083681.HK\uff09\u5171\u540c\u6388\u4e88\u96f2\u9802\u65b0\u8000\u5728\u5168\u7403\u7bc4\u570d\u5167\u814e\u81df\u75be\u75c5\u9818\u57df\u958b\u767c\u548c\u5546\u696d\u5316\u7684\u6b0a\u5229\u3002\u8a72\u7522\u54c1\u6b63\u5728\u5168\u7403\u7bc4\u570d\u5167\u958b\u767c\u7528\u65bc\u6cbb\u7642\u814e\u75c5\u3002BTK\u662fB\u7d30\u80de\u53d7\u9ad4\u4fe1\u865f\u901a\u8def\u7684\u91cd\u8981\u7d44\u6210\u90e8\u5206\uff0c\u53ef\u8abf\u7bc0B\u6dcb\u5df4\u7d30\u80de\u7684\u5b58\u6d3b\u3001\u6fc0\u6d3b\u3001\u589e\u6b96\u548c\u5206\u5316\u3002\u56e0\u6b64\uff0c\u61c9\u7528\u5c0f\u5206\u5b50\u6291\u5236\u5291\u9776\u5411BTK\u662f\u6cbb\u7642B\u7d30\u80de\u6dcb\u5df4\u7624\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u6709\u6548\u9078\u64c7\u3002<\/p>\n<p><b>\u95dc\u65bc\u96f2\u9802\u65b0\u8000<\/b><br \/>\u96f2\u9802\u65b0\u8000\u662f\u4e00\u5bb6\u5c08\u6ce8\u65bc\u5275\u65b0\u85e5\u7814\u767c\u3001\u81e8\u5e8a\u958b\u767c\u3001\u88fd\u9020\u548c\u5546\u696d\u5316\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u6eff\u8db3\u5168\u7403\u5e02\u5834\u5c1a\u672a\u6eff\u8db3\u7684\u91ab\u7642\u9700\u6c42\u3002\u96f2\u9802\u65b0\u8000\u7684\u7ba1\u7406\u5718\u968a\u5728\u4e2d\u570b\u53ca\u5168\u7403\u9818\u5148\u88fd\u85e5\u4f01\u696d\u64c1\u6709\u6df1\u539a\u7684\u5c08\u9577\u548c\u8c50\u5bcc\u7684\u7d93\u9a57\u3002\u516c\u53f8\u5728\u6d59\u6c5f\u5609\u5584\u64c1\u6709\u5177\u5099\u5546\u696d\u5316\u898f\u6a21\u7684\u5168\u7403\u751f\u7522\u57fa\u5730\uff0c\u4e26\u4f9d\u64da\u4e2d\u570b\u3001\u7f8e\u570b\u53ca\u6b50\u76df\u6a19\u6e96\u5efa\u7acb\u4e86\u5b8c\u5584\u7684GMP\u751f\u7522\u8cea\u91cf\u7ba1\u7406\u9ad4\u7cfb\u3002<\/p>\n<p>\u516c\u53f8\u805a\u7126\u81ea\u8eab\u514d\u75ab\u3001\u773c\u79d1\u3001\u6025\u91cd\u75c7\u53caCKM\uff08\u5fc3\u8840\u7ba1\u3001\u814e\u81df\u53ca\u4ee3\u8b1d\uff09\u7b49\u75be\u75c5\u6cbb\u7642\u9818\u57df\uff0c\u5df2\u6253\u9020\u96c6\u5168\u6e20\u9053\u5546\u696d\u5316\u9ad4\u7cfb\u8207\u85e5\u54c1\u5168\u751f\u547d\u9031\u671f\u5546\u696d\u5316\u80fd\u529b\u65bc\u4e00\u9ad4\u7684\u5546\u696d\u5316\u5e73\u53f0\uff0c\u4e26\u4ee5\u64c1\u6709\u5168\u7403\u6b0a\u76ca\u7684\u81ea\u7814mRNA\u5e73\u53f0\u70ba\u57fa\u790e\uff0c\u6301\u7e8c\u63a8\u9032mRNA in vivo CAR-T\u8207mRNA\u816b\u7624\u75ab\u82d7\u7b49\u73fe\u6709\u7ba1\u7dda\uff0c\u540c\u6642\u901a\u904e\u5f15\u9032\u53ca\u751f\u614b\u5b75\u5316\u6f5b\u529b\u5e73\u53f0\uff0c\u62d3\u5c55\u7814\u767c\u80fd\u529b\uff0c\u540c\u6642\u5f37\u5316\u5168\u7403\u5316\u4f48\u5c40\uff0c\u52a0\u5feb\u570b\u969b\u5316\u767c\u5c55\u9032\u7a0b\u3002\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u516c\u53f8\u5b98\u7db2\uff1a<a href=\"http:\/\/www.everestmedicines.com\/\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\"><b>www.everestmedicines.com<\/b><\/a>\u3002<\/p>\n<p><b>\u95dc\u65bc<\/b>\u00a0<b>Travere Therapeutics<\/b><\/p>\n<p>Travere\u662f\u4e00\u5bb6\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u5176\u4f7f\u547d\u662f\u300c\u5c08\u6ce8\u7f55\u75c5\uff0c\u7d42\u8eab\u627f\u8afe\uff08In Rare For Life\uff09\u300d\u3002\u5718\u968a\u65e5\u5fa9\u4e00\u65e5\u5730\u9f4a\u5fc3\u5354\u529b\uff0c\u5e6b\u52a9\u4f86\u81ea\u4e0d\u540c\u80cc\u666f\u7684\u60a3\u8005\u3001\u5bb6\u5ead\u53ca\u7167\u8b77\u8005\u61c9\u5c0d\u7f55\u898b\u75be\u75c5\u5e36\u4f86\u7684\u751f\u6d3b\u6311\u6230\u3002\u5728\u9019\u689d\u9053\u8def\u4e0a\uff0cTravere\u6df1\u77e5\u6cbb\u7642\u9078\u64c7\u7684\u9700\u6c42\u523b\u4e0d\u5bb9\u7de9\uff0c\u56e0\u6b64Travere\u7684\u5168\u7403\u5718\u968a\u8207\u7f55\u898b\u75be\u75c5\u793e\u7fa4\u5408\u4f5c\uff0c\u5171\u540c\u8b58\u5225\u3001\u958b\u767c\u53ca\u63d0\u4f9b\u6539\u8b8a\u751f\u547d\u7684\u7642\u6cd5\u3002\u70ba\u5be6\u8e10\u6b64\u4f7f\u547d\uff0cTravere\u6301\u7e8c\u5c0b\u6c42\u7406\u89e3\u7f55\u898b\u75be\u75c5\u60a3\u8005\u7684\u4e0d\u540c\u89c0\u9ede\uff0c\u52c7\u6562\u958b\u95e2\u65b0\u8def\u5f91\uff0c\u4ee5\u6539\u8b8a\u5176\u751f\u6d3b\u4e26\u5e36\u4f86\u5e0c\u671b\u2014\u2014\u7121\u8ad6\u662f\u4eca\u5929\u9084\u662f\u672a\u4f86\u3002\u6709\u95dc\u66f4\u591a\u8cc7\u6599\uff0c\u8acb\u53c3\u95b1 <a href=\"https:\/\/travere.com\/\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\"><b>travere.com<\/b><\/a>\u3002<\/p>\n<p><b>\u524d\u77bb\u6027\u8072\u660e<\/b><br 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in vivo CAR-T\u8207mRNA\u816b\u7624\u75ab\u82d7\u7b49\u73fe\u6709\u7ba1\u7dda\uff0c\u540c\u6642\u901a\u904e\u5f15\u9032\u53ca\u751f\u614b\u5b75\u5316\u6f5b\u529b\u5e73\u53f0\uff0c\u62d3\u5c55\u7814\u767c\u80fd\u529b\uff0c\u540c\u6642\u5f37\u5316\u5168\u7403\u5316\u4f48\u5c40\uff0c\u52a0\u5feb\u570b\u969b\u5316\u767c\u5c55\u9032\u7a0b\u3002\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u516c\u53f8\u5b98\u7db2\uff1awww.everestmedicines.com\u3002 \u95dc\u65bc\u00a0Travere Therapeutics Travere\u662f\u4e00\u5bb6\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u5176\u4f7f\u547d\u662f\u300c\u5c08\u6ce8\u7f55\u75c5\uff0c\u7d42\u8eab\u627f\u8afe\uff08In Rare For Life\uff09\u300d\u3002\u5718\u968a\u65e5\u5fa9\u4e00\u65e5\u5730\u9f4a\u5fc3\u5354\u529b\uff0c\u5e6b\u52a9\u4f86\u81ea\u4e0d\u540c\u80cc\u666f\u7684\u60a3\u8005\u3001\u5bb6\u5ead\u53ca\u7167\u8b77\u8005\u61c9\u5c0d\u7f55\u898b\u75be\u75c5\u5e36\u4f86\u7684\u751f\u6d3b\u6311\u6230\u3002\u5728\u9019\u689d\u9053\u8def\u4e0a\uff0cTravere\u6df1\u77e5\u6cbb\u7642\u9078\u64c7\u7684\u9700\u6c42\u523b\u4e0d\u5bb9\u7de9\uff0c\u56e0\u6b64Travere\u7684\u5168\u7403\u5718\u968a\u8207\u7f55\u898b\u75be\u75c5\u793e\u7fa4\u5408\u4f5c\uff0c\u5171\u540c\u8b58\u5225\u3001\u958b\u767c\u53ca\u63d0\u4f9b\u6539\u8b8a\u751f\u547d\u7684\u7642\u6cd5\u3002\u70ba\u5be6\u8e10\u6b64\u4f7f\u547d\uff0cTravere\u6301\u7e8c\u5c0b\u6c42\u7406\u89e3\u7f55\u898b\u75be\u75c5\u60a3\u8005\u7684\u4e0d\u540c\u89c0\u9ede\uff0c\u52c7\u6562\u958b\u95e2\u65b0\u8def\u5f91\uff0c\u4ee5\u6539\u8b8a\u5176\u751f\u6d3b\u4e26\u5e36\u4f86\u5e0c\u671b\u2014\u2014\u7121\u8ad6\u662f\u4eca\u5929\u9084\u662f\u672a\u4f86\u3002\u6709\u95dc\u66f4\u591a\u8cc7\u6599\uff0c\u8acb\u53c3\u95b1 travere.com\u3002 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\u6839\u64da\u5354\u8b70\uff0c\u96f2\u9802\u65b0\u8000\u5c07\u7372\u5f971.125\u5104\u7f8e\u5143\u7684\u9996\u4ed8\u6b3e\uff0c\u4e26\u6709\u8cc7\u683c\u5728\u6700\u591a\u4e94\u500b\u9069\u61c9\u75c7\u4e0a\u7372\u5f97\u9ad8\u905410.3\u5104\u7f8e\u5143\u7684\u958b\u767c\u3001\u8a3b\u518a\u53ca\u5546\u696d\u5316\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002\u6b64\u5916\uff0c\u516c\u53f8\u9084\u5c07\u57fa\u65bcEVER001\u7684\u672a\u4f86\u5e74\u5ea6\u6de8\u92b7\u552e\u984d\uff0c\u7372\u5f97\u5f9e\u9ad8\u500b\u4f4d\u6578\u81f3\u96d9\u4f4d\u6578\u767e\u5206\u6bd4\u7684\u5206\u7d1a\u7279\u8a31\u6b0a\u4f7f\u7528\u8cbb\u3002  EVER001\u662f\u96f2\u9802\u65b0\u8000\u7684\u65b0\u4e00\u4ee3\u5171\u50f9\u53ef\u9006\u5e03\u9b6f\u9813\u916a\u6c28\u9178\u6fc0\u9176\uff08BTK\uff09\u6291\u5236\u5291\uff0c\u5177\u5099\u300c\u4e00\u500b\u53ef\u4ee5\u958b\u767c\u591a\u7a2e\u9069\u61c9\u75c7\u7684\u85e5\u7269\uff08pipeline-in-a-product\uff09\u300d\u7684\u958b\u767c\u6f5b\u529b\uff0c\u6709\u671b\u70ba\u5168\u7403\u903e1000\u842c\u60a3\u6709\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\uff08PMN\uff09\u3001IgA\u814e\u75c5\u3001\u5fae\u5c0f\u75c5\u8b8a\u6027\u814e\u75c5\uff08MCD\uff09\u3001\u5c40\u7076\u7bc0\u6bb5\u6027\u814e\u5c0f\u7403\u786c\u5316\uff08FSGS\uff09\u548c\u72fc\u7621\u6027\u814e\u708e\u7b49\u75be\u75c5\u7684\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u6cbb\u7642\u9078\u64c7\uff0c\u4e26\u5c55\u73fe\u51fa\u6f5b\u5728\u7684\u5ee3\u6cdb\u61c9\u7528\u50f9\u503c\u3002  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Therapeutics\u300d\uff09\u9054\u6210\u7368\u5bb6\u6388\u6b0a\u8a31\u53ef\u8207\u5408\u4f5c\u5354\u8b70\u3002\u6839\u64da\u5354\u8b70\uff0cTravere Therapeutics\u5c07\u7372\u5f97EVER001\uff08\u5e0c\u5e03\u66ff\u5c3c\uff0ccivorebrutinib\uff09\u9664\u5927\u4e2d\u83ef\u5340\u53ca\u90e8\u5206\u6771\u5357\u4e9e\u570b\u5bb6\u4ee5\u5916\u5340\u57df\u7684\u7368\u5bb6\u958b\u767c\u53ca\u5546\u696d\u5316\u6b0a\u76ca\u3002\u6b64\u6b21\u5408\u4f5c\u5c07\u52a0\u901fEVER001\u7684\u5168\u7403\u81e8\u5e8a\u958b\u767c\u8207\u5546\u696d\u5316\u9032\u7a0b\uff0c\u70ba\u5168\u7403\u814e\u75c5\u60a3\u8005\u5e36\u4f86\u5275\u65b0\u6cbb\u7642\u9078\u64c7\u3002 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