{"id":440722,"date":"2026-06-01T09:06:00","date_gmt":"2026-06-01T01:06:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=440722"},"modified":"2026-06-01T09:06:00","modified_gmt":"2026-06-01T01:06:00","slug":"%e3%80%90%e7%9b%b4%e6%93%8aasco-2026%e3%80%91%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5%e8%80%90%e7%ab%8b%e5%85%8b%e6%b2%bb%e7%99%82cml-lbp%e8%88%87ph-bcp-all%e6%95%b8%e6%93%9a%e7%99%bc%e4%bd%88","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=440722","title":{"rendered":"\u3010\u76f4\u64caASCO 2026\u3011\u4e9e\u76db\u91ab\u85e5\u8010\u7acb\u514b\u00ae\u6cbb\u7642CML-LBP\u8207Ph+ BCP-ALL\u6578\u64da\u767c\u4f48\uff0c\u6709\u671b\u586b\u88dc\u6025\u8b8a\u671f\u6cbb\u7642\u7a7a\u767d"},"content":{"rendered":"<div>\n<table name=\"logo_release\" border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span 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id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p>\u4e00\u5e74\u4e00\u5ea6\u7684ASCO\u5e74\u6703\u662f\u5168\u7403\u816b\u7624\u9818\u57df\u6700\u91cd\u8981\u7684\u3001\u6700\u70ba\u6b0a\u5a01\u7684\u5b78\u8853\u4ea4\u6d41\u76db\u6703\uff0c\u5c07\u5c55\u793a\u7576\u524d\u570b\u969b\u6700\u524d\u6cbf\u7684\u81e8\u5e8a\u816b\u7624\u5b78\u79d1\u7814\u6210\u679c\u548c\u816b\u7624\u6cbb\u7642\u6280\u8853\u3002\u4eca\u5e74\u662f\u4e9e\u76db\u91ab\u85e5\u9023\u7e8c\u7b2c\u4e5d\u5e74\u4eae\u76f8ASCO\u5e74\u6703\uff0c\u6b64\u6b21\u516c\u53f8\u4e09\u500b\u91cd\u9ede\u54c1\u7a2e\u5171\u6709\u516d\u9805\u7814\u7a76\u5165\u9078\uff0c\u5176\u4e2d\u4e09\u9805\u7372\u5feb\u901f\u53e3\u982d\u5831\u544a\u3002<\/p>\n<p>\u6b64\u6b21\u5feb\u901f\u53e3\u982d\u5831\u544a\u7684\u7814\u7a76\u70ba\u8010\u7acb\u514b<sup>\u00ae<\/sup>\u806f\u5408\u8c9d\u6797\u59a5\u6b50\u55ae\u6297\u5728\u6d77\u5916\u4eba\u7fa4\u4e2d\u7684\u9996\u6b21\u62ab\u9732\u3002\u6578\u64da\u986f\u793a\uff0c\u8a72\u806f\u5408\u65b9\u6848\u5728\u5fa9\u767c\/\u96e3\u6cbb\u6027Ph+ BCP-ALL\u6216CML-LBP\u60a3\u8005\u4e2d\u5c55\u73fe\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u81e8\u5e8a\u6d3b\u6027\uff0c\u7de9\u89e3\u7387\u548c\u5fae\u5c0f\u6b98\u7559\u75c5\uff08MRD)\u9670\u6027\u7387\u5747\u8868\u73fe\u7a4d\u6975\uff1b\u5728\u5b89\u5168\u6027\u65b9\u9762\uff0c\u8a72\u806f\u5408\u65b9\u6848\u7e3d\u9ad4\u8010\u53d7\u6027\u826f\u597d\uff0c\u5b89\u5168\u6027\u7279\u5fb5\u8207\u5404\u55ae\u85e5\u5df2\u77e5\u6bd2\u6027\u4e00\u81f4\u3002<\/p>\n<p>\u8010\u7acb\u514b<sup>\u00ae<\/sup>\u662f\u4e9e\u76db\u91ab\u85e5\u539f\u52751\u985e\u65b0\u85e5\uff0c\u70ba\u4e2d\u570b\u9996\u500b\u7372\u6279\u4e0a\u5e02\u7684\u7b2c\u4e09\u4ee3BCR-ABL\u6291\u5236\u5291\u3002\u5176\u5728\u4e2d\u570b\u7684\u5546\u696d\u5316\u63a8\u5ee3\u7531\u4e9e\u76db\u91ab\u85e5\u548c\u4fe1\u9054\u751f\u7269\u5171\u540c\u8ca0\u8cac\u3002\u76ee\u524d\uff0c\u8010\u7acb\u514b<sup>\u00ae<\/sup>\u5df2\u5728\u4e2d\u570b\u7372\u6279\u7684\u9069\u61c9\u75c7\u70ba\uff1a\u6cbb\u7642\u4efb\u4f55\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5291\uff08TKI\uff09\u8010\u85e5\u3001\u4e26\u4f34\u6709T315I\u7a81\u8b8a\u7684\u6162\u6027\u9ad3\u7d30\u80de\u767d\u8840\u75c5\uff08CML\uff09\u6162\u6027\u671f\uff08-CP\uff09\u548c\u52a0\u901f\u671f\uff08-AP\uff09\u7684\u6210\u5e74\u60a3\u8005\uff1b\u4ee5\u53ca\u6cbb\u7642\u5c0d\u4e00\u4ee3\u548c\u4e8c\u4ee3TKI\u8010\u85e5\u548c\/\u6216\u4e0d\u8010\u53d7\u7684CML-CP\u6210\u5e74\u60a3\u8005\uff0c\u4e14\u6240\u6709\u7372\u6279\u9069\u61c9\u75c7\u5747\u5df2\u88ab\u7d0d\u5165\u570b\u5bb6\u91ab\u4fdd\u85e5\u54c1\u76ee\u9304\u3002\u76ee\u524d\uff0c\u4e9e\u76db\u91ab\u85e5\u6b63\u958b\u5c55\u8010\u7acb\u514b<sup>\u00ae<\/sup>\u4e09\u9805\u5168\u7403\u8a3b\u518aIII\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u6d89\u53caCML-CP\u3001\u65b0\u8a3a\u65b7\u7684\u8cbb\u57ce\u67d3\u8272\u9ad4\u967d\u6027\u6025\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u8840\u75c5\uff08Ph+ ALL\uff09\u3001\u7425\u73c0\u9178\u812b\u6c2b\u9176\uff08SDH\uff09\u7f3a\u9677\u578b\u80c3\u8178\u9053\u9593\u8cea\u7624\uff08GIST\uff09\u5e7e\u5927\u9069\u61c9\u75c7\uff0c\u4e14\u5176\u4e2d\u5169\u9805\u7372\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u548c\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u8a31\u53ef\u958b\u5c55\u3002\u6b64\u5916\uff0c\u4e9e\u76db\u91ab\u85e5\u5df2\u7d93\u8207\u8de8\u570b\u88fd\u85e5\u4f01\u696d\u6b66\u7530\u5c31\u8010\u7acb\u514b<sup>\u00ae<\/sup>\u7c3d\u7f72\u4e86\u4e00\u9805\u7368\u5bb6\u9078\u64c7\u6b0a\u4e8b\u5b9c\u3002\u4e00\u65e6\u884c\u4f7f\u9078\u64c7\u6b0a\uff0c\u6b66\u7530\u5c07\u7372\u5f97\u958b\u767c\u53ca\u5546\u696d\u5316\u8010\u7acb\u514b<sup>\u00ae<\/sup>\u7684\u5168\u7403\u6b0a\u5229\u8a31\u53ef\uff0c\u60df\u4e2d\u570b\u5927\u9678\u3001\u4e2d\u570b\u9999\u6e2f\u7279\u5225\u884c\u653f\u5340\u3001\u4e2d\u570b\u6fb3\u9580\u7279\u5225\u884c\u653f\u5340\u3001\u4e2d\u570b\u53f0\u7063\u7b49\u5730\u5340\u9664\u5916\u3002<\/p>\n<p><b>\u8a72\u9805\u81e8\u5e8a\u7814\u7a76\u7684\u4e3b\u8981\u7814\u7a76\u8005\u3001\u7f8e\u570b\u5fb7\u514b\u85a9\u65af\u5927\u5b78<\/b><b>MD<\/b><b>\u5b89\u5fb7\u68ee\u764c\u75c7\u4e2d\u5fc3\u767d\u8840\u75c5\u79d1<\/b><b>Elias Jabbour<\/b><b>\u6559\u6388<\/b>\u8868\u793a\uff1a\u300c\u5fa9\u767c\/\u96e3\u6cbb\u6027Ph\u967d\u6027ALL\u6216CML\u6dcb\u7cfb\u6025\u8b8a\u671f\u60a3\u8005\u7684\u6cbb\u7642\u5b58\u5728\u5de8\u5927\u7684\u672a\u6eff\u8db3\u81e8\u5e8a\u9700\u6c42\u3002\u5967\u96f7\u5df4\u66ff\u5c3c\u806f\u5408\u8c9d\u6797\u59a5\u6b50\u55ae\u6297\u5c55\u73fe\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u6d3b\u6027\u548c\u8010\u53d7\u6027\uff0c\u51f8\u986f\u4e86\u9019\u4e00\u53bb\u5316\u7642\u65b0\u7b56\u7565\u5728\u6b64\u985e\u96e3\u6cbb\u6027\u75be\u75c5\u4e2d\u7684\u6f5b\u529b\u3002\u300d<\/p>\n<p><b>\u4e9e\u76db\u91ab\u85e5\u9996\u5e2d\u91ab\u5b78\u5b98\u7fdf\u4e00\u5e06\u535a\u58eb\u8868\u793a\uff1a<\/b>\u300c\u6b64\u6b21\u5feb\u901f\u53e3\u982d\u5831\u544a\u7684\u7814\u7a76\u9996\u6b21\u5728\u570b\u969b\u60a3\u8005\u4e2d\u9a57\u8b49\u4e86\u8010\u7acb\u514b<sup>\u00ae<\/sup>\u806f\u5408\u8c9d\u6797\u59a5\u6b50\u55ae\u6297\u91dd\u5c0dCML-LBP\u8207R\/R Ph+ BCP-ALL\u7684\u6cbb\u7642\u6f5b\u529b\u3002\u9019\u5169\u500b\u9818\u57df\u9577\u671f\u88ab\u8996\u70baBCR-ABL\u9a45\u52d5\u8840\u6db2\u816b\u7624\u4e2d\u300e\u6700\u96e3\u5543\u7684\u9aa8\u982d\u300f\uff0c \u4ee3\u8868\u4e86\u9810\u5f8c\u6700\u5dee\u3001\u6cbb\u7642\u9078\u64c7\u6700\u5c11\u7684\u5169\u985e\u7d42\u672b\u968e\u6bb5\u3002\u6b64\u6b21\u5c55\u793a\u7684\u6578\u64da\u975e\u5e38\u4ee4\u4eba\u9f13\u821e\uff0c\u6709\u671b\u586b\u88dc\u6025\u8b8a\u671f\u6cbb\u7642\u7684\u9577\u671f\u7a7a\u767d\u3002\u6211\u5011\u671f\u5f85\u901a\u904e\u5f8c\u7e8c\u7814\u7a76\uff0c\u5c07\u9019\u4e00\u6210\u679c\u8f49\u5316\u70ba\u60a3\u8005\u7684\u6301\u7e8c\u7372\u76ca\u3002\u672a\u4f86\uff0c\u6211\u5011\u5c07\u7e7c\u7e8c\u79c9\u6301\u521d\u5fc3\uff0c\u5805\u5b88\u300e\u89e3\u6c7a\u4e2d\u570b\u4e43\u81f3\u5168\u7403\u60a3\u8005\u5c1a\u672a\u6eff\u8db3\u7684\u81e8\u5e8a\u9700\u6c42\u300f\u9019\u4e00\u4f7f\u547d\uff0c\u52a0\u5feb\u81e8\u5e8a\u958b\u767c\uff0c\u8b93\u66f4\u591a\u5b89\u5168\u6709\u6548\u7684\u85e5\u7269\u76e1\u5feb\u4e0a\u5e02\uff0c\u65e9\u65e5\u60e0\u53ca\u60a3\u8005\u3002\u300d<\/p>\n<p>\u6b64\u9805\u7814\u7a76\u57282026 ASCO\u5e74\u6703\u4e0a\u5c55\u793a\u7684\u6838\u5fc3\u8981\u9ede\u5982\u4e0b\uff1a<\/p>\n<p><b>Olverembatinib (HQP1351) combined with blinatumomab in patients with lymphoid blast phase chronic myeloid leukemia (CML-LBP) or Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia (Ph+ BCP-ALL)<br \/><\/b><b>\u5967\u96f7\u5df4\u66ff\u5c3c\uff08<\/b><b>HQP1351<\/b><b>\uff09\u806f\u5408\u8c9d\u6797\u59a5\u6b50\u55ae\u6297\u6cbb\u7642\u6dcb\u7cfb\u6025\u8b8a\u671f\u6162\u6027\u9ad3\u7d30\u80de\u767d\u8840\u75c5\uff08<\/b><b>CML-LBP<\/b><b>\uff09\u6216\u8cbb\u57ce\u67d3\u8272\u9ad4\u967d\u6027<\/b><b>B<\/b><b>\u7d30\u80de\u524d\u9ad4\u6025\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u8840\u75c5\uff08<\/b><b>Ph+ BCP-ALL<\/b><b>\uff09\u60a3\u8005<br \/><\/b><b>\u6458\u8981\u7de8\u865f\uff1a<\/b>6513<br \/><b>\u5c55\u793a\u5f62\u5f0f\uff1a<\/b>\u5feb\u901f\u53e3\u982d\u5831\u544a<br \/><b>\u5206\u6703\u5834\u6a19\u984c\uff1a<\/b>\u8840\u6db2\u7cfb\u7d71\u60e1\u6027\u816b\u7624\u2014\u2014\u767d\u8840\u75c5\u3001\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u5f81\u53ca\u540c\u7a2e\u7570\u9ad4\u79fb\u690d\uff08Hematologic Malignancies\u2014Leukemia, Myelodysplastic Syndromes, and Allotransplant\uff09<br \/><b>\u7b2c\u4e00\u4f5c\u8005\uff1a<\/b>Elias Jabbour, MD\uff0c\u7f8e\u570b\u5fb7\u514b\u85a9\u65af\u5927\u5b78MD\u5b89\u5fb7\u68ee\u764c\u75c7\u4e2d\u5fc3\u767d\u8840\u75c5\u79d1<br \/><b>\u6838\u5fc3\u8981\u9ede\uff1a <\/b><\/p>\n<ul 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