{"id":436661,"date":"2026-05-18T16:31:00","date_gmt":"2026-05-18T08:31:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=436661"},"modified":"2026-05-18T16:31:00","modified_gmt":"2026-05-18T08:31:00","slug":"%e5%ba%b7%e9%9c%88%e9%a6%96%e7%99%bb-eco-2026-%e5%8f%a3%e9%a0%ad%e7%99%bc%e8%a1%a8-cbl-514-%e4%bd%b5%e7%94%a8-glp-1r-%e9%a1%9e%e6%b8%9b%e9%87%8d%e8%97%a5%e7%89%a9%e5%8b%95%e7%89%a9%e6%95%b8%e6%93%9a","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=436661","title":{"rendered":"\u5eb7\u9708\u9996\u767b ECO 2026 \u53e3\u982d\u767c\u8868 CBL-514 \u4f75\u7528 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u52d5\u7269\u6578\u64da \u5168\u8eab\u6027\u4ee3\u8b1d\u6548\u679c\u5438\u5f15\u570b\u969b\u5c08\u5bb6\u53ca\u5927\u85e5\u5ee0\u9ad8\u5ea6\u8208\u8da3"},"content":{"rendered":"
\n\n\n\n
<\/a>
\u5eb7\u9708\u9996\u5ea6\u4eae\u76f8ECO 2026\u53e3\u982d\u767c\u8868\uff0c\u73fe\u5834\u53c3\u8207\u71b1\u7d61\uff0c\u5438\u5f15\u8d85\u904e300\u4f4d\u4f86\u81ea\u570b\u969b\u5927\u85e5\u5ee0\u3001\u81e8\u5e8a\u91ab\u5e2b\u53ca\u5c08\u5bb6\u5b78\u8005\u7b49\u7522\u696d\u4eba\u58eb\u8046\u807d\u3002<\/span><\/p>\n<\/p><\/div>\n

\u6b50\u6d32\u80a5\u80d6\u75c7\u5927\u6703\uff08ECO\uff09\u70ba\u5168\u7403\u80a5\u80d6\u8207\u4ee3\u8b1d\u91ab\u5b78\u9818\u57df\u5177\u91cd\u8981\u5f71\u97ff\u529b\u7684\u570b\u969b\u76db\u6703\u4e4b\u4e00\uff0c\u6bcf\u5e74\u532f\u805a\u4f86\u81ea\u8d85\u904e100\u500b\u570b\u5bb6\u3001\u903e4,000\u540d\u80a5\u80d6\u91ab\u5b78\u3001\u4ee3\u8b1d\u75be\u75c5\u8207\u9ad4\u91cd\u7ba1\u7406\u9818\u57df\u5c08\u5bb6\uff0c\u5206\u4eab\u6700\u65b0\u8da8\u52e2\u8207\u65b0\u85e5\u7814\u767c\u9032\u5c55\u3002\u8b1b\u8005 Dr. Sharma \u70ba\u5168\u7403\u5c07\u80a5\u80d6\u8996\u70ba\u300c\u6162\u6027\u75be\u75c5\u300d\u7684\u5148\u9a45\uff0c\u4ea6\u66fe\u53d7\u9080\u64d4\u4efb\u827e\u4f2f\u7dad\u3001\u963f\u65af\u7279\u6377\u5229\u5eb7\u3001\u767e\u9748\u4f73\u6bb7\u683c\u7ff0\u3001\u79ae\u4f86\u8207\u8afe\u548c\u8afe\u5fb7\u7b49\u8de8\u570b\u5927\u85e5\u5ee0\u5728\u80a5\u80d6\u91ab\u5b78\u9818\u57df\u7684\u79d1\u5b78\u9867\u554f\u8207\u8b1b\u8005\u3002<\/p>\n

\u672c\u6b21\u53e3\u982d\u767c\u8868\u73fe\u5834\u53c3\u8207\u8e34\u8e8d\uff0c\u5171\u5438\u5f15\u8d85\u904e300\u4f4d\u807d\u773e\u53c3\u8207\uff0c\u5305\u62ec\u8de8\u570b\u85e5\u5ee0\u4ee3\u8868\u3001\u81e8\u5e8a\u91ab\u5e2b\u3001\u5c08\u5bb6\u5b78\u8005\u53ca\u7522\u696d\u4eba\u58eb\uff0c\u9032\u4e00\u6b65\u63d0\u5347 CBL-514 \u65bc\u570b\u969b\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u4e4b\u80fd\u898b\u5ea6\u3002<\/p>\n

\u672c\u6b21\u767c\u8868\u7684\u7814\u7a76\u6db5\u84cb CBL-514 \u5206\u5225\u8207\u5169\u5927\u4e3b\u6d41 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269 Semaglutide \u53ca Tirzepatide \u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u7d50\u679c\uff0c\u7d50\u679c\u986f\u793a\uff0cCBL-514 \u4f75\u7528 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u5f8c\uff0c\u65bc\u52d5\u7269\u5be6\u9a57\u4e2d\u5c55\u73fe\u56db\u9805\u5177\u4e92\u88dc\u3001\u5354\u540c\u6027\u7684\u61c9\u7528\u6f5b\u529b\uff1a<\/p>\n

    \n
  1. \u66f4\u5f37\u7684\u6e1b\u91cd\u6548\u679c<\/b>\uff1a\u4ee5\u8207Semaglutide\u4f75\u7528\u7814\u7a76\u70ba\u4f8b\uff0cCBL-514\u4f75\u7528\u7d44\u76f8\u8f03 Semaglutide \u55ae\u7528\u7d44\uff0c\u9ad4\u91cd\u4e0b\u964d\u5e45\u5ea6\u9032\u4e00\u6b65\u63d0\u534791.5%<\/span>\u3002\u986f\u793a\u4f75\u7528\u7626\u7626\u91dd\u5177\u5099\u9032\u4e00\u6b65\u589e\u5f37\u9ad4\u91cd\u4e0b\u964d\u4e4b\u6f5b\u529b\u3002<\/li>\n
  2. \u66f4\u6301\u4e45\u7684\u505c\u85e5\u5f8c\u9ad4\u91cd\u7dad\u6301<\/b>\uff1a\u4ee5 Tirzepatide \u7814\u7a76\u70ba\u4f8b\uff0cTirzepatide \u55ae\u7528\u7d44\u65bc\u505c\u85e5\u5f8c\u9ad4\u91cd\u56de\u5347\u5e45\u5ea6\u70ba55.9%\uff0c\u800cCBL-514 \u4f75\u7528\u7d44\u9ad4\u91cd\u56de\u5347\u5e45\u5ea6\u50c525.2%<\/span>\u3002\u986f\u793aCBL-514 \u4f75\u7528\u7626\u7626\u91dd\u65bc\u505c\u85e5\u5f8c\uff0c\u5177\u5099\u6e1b\u7de9\u9ad4\u91cd\u56de\u5347\u4e4b\u6f5b\u529b\u3002<\/li>\n
  3. \u66f4\u986f\u8457\u7684\u76ae\u4e0b\u8207\u5167\u81df\u8102\u80aa\u6e1b\u5c11<\/b>\uff1a\u65bc GLP-1R \u985e\u85e5\u7269\u505c\u7528\u5f8c\uff0c CBL-514 \u4f75\u7528\u7d44\u53ef\u9032\u4e00\u6b65\u984d\u5916\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa182.5%\u8207\u5167\u81df\u8102\u80aa367.4%<\/span>\u3002\u5177\u5099\u512a\u5316\u9ad4\u7d44\u6210\u4e4b\u6f5b\u529b\u3002<\/li>\n
  4. \u809d\u81df\u4ee3\u8b1d\u6307\u6a19\u6539\u5584<\/b>\uff1a\u672c\u6b21 ECO \u53e3\u982d\u767c\u8868\u4ea6\u9996\u5ea6\u63ed\u793a CBL-514 \u4f75\u7528 Semaglutide \u5f8c\uff0c\u65bc\u809d\u81df\u4ee3\u8b1d\u76f8\u95dc\u6307\u6a19\u4e0a\u7684\u6539\u5584\u3002\u7d50\u679c\u986f\u793a\uff0c\u76f8\u8f03\u65bc\u5c0d\u7167\u7d44\uff0cCBL-514 \u4f75\u7528 Semaglutide \u7d44\u4e4b\u809d\u81df\u8102\u8cea\u542b\u91cf\u4e0b\u964d40.4%\uff0c\u809d\u81df\u81bd\u56fa\u9187\u4e0b\u964d52.7%<\/span>\uff1b\u5728\u809d\u81df\u7d44\u7e54\u75c5\u7406\u5206\u6790\u4e2d\uff0c\u4ea6\u89c0\u5bdf\u5230\u8102\u80aa\u8b8a\u6027\u3001\u767c\u708e\u53ca\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u6d3b\u52d5\u5ea6\u8a55\u5206\uff08NAS score\uff09\u7b49\u809d\u81df\u50b7\u5bb3\u76f8\u95dc\u6307\u6a19\u6539\u5584\u3002\u6b64\u7d50\u679c\u986f\u793a\uff0cCBL-514 \u8207 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u4f75\u7528\uff0c\u5728\u52d5\u7269\u5be6\u9a57\u4e2d\u9664\u9ad4\u91cd\u7dad\u6301\u8207\u8102\u80aa\u6e1b\u5c11\u5916\uff0c\u4ea6\u5448\u73fe\u6539\u5584\u809d\u81df\u4ee3\u8b1d\u8207\u767c\u708e\u72c0\u614b\u4e4b\u6f5b\u5728\u79d1\u5b78\u610f\u7fa9\u3002<\/li>\n<\/ol>\n

    \u5eb7\u9708\u526f\u7e3d\u937e\u742d\u74a3\u8868\u793a\uff1a\u300c\u6211\u5011\u5f88\u69ae\u5e78\u7531 Dr. Sharma \u9019\u6a23\u5177\u570b\u969b\u5f71\u97ff\u529b\u7684\u80a5\u80d6\u91ab\u5b78\u6b0a\u5a01\uff0c\u65bc ECO 2026 \u5411\u5168\u7403\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u5c08\u5bb6\u767c\u8868 CBL-514 \u8207 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u6578\u64da\u3002\u672c\u6b21\u53e3\u982d\u767c\u8868\u73fe\u5834\u53c3\u8207\u5ea6\u9ad8\uff0c\u5438\u5f15\u8d85\u904e300\u4f4d\u807d\u773e\uff0c\u5305\u62ec\u8de8\u570b\u85e5\u5ee0\u4ee3\u8868\u3001\u81e8\u5e8a\u91ab\u5e2b\u3001\u5c08\u5bb6\u5b78\u8005\u53ca\u7522\u696d\u4eba\u58eb\uff0c\u6709\u52a9\u65bc\u63d0\u5347 CBL-514 \u5728\u570b\u969b\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u7684\u80fd\u898b\u5ea6\uff0c\u4e26\u6df1\u5316\u8207\u95dc\u9375\u6f5b\u5728\u5408\u4f5c\u5925\u4f34\u7684\u4ea4\u6d41\u3002\u300d<\/p>\n

    \u937e\u742d\u74a3\u526f\u7e3d\u9032\u4e00\u6b65\u6307\u51fa\uff1a\u300c\u96a8\u8457 GLP-1R \u985e\u85e5\u7269\u5feb\u901f\u6539\u8b8a\u5168\u7403\u6e1b\u91cd\u5e02\u5834\uff0c\u5728\u7626\u7626\u91dd\u6210\u529f\u5e6b\u60a3\u8005\u9ad4\u91cd\u6e1b\u8f15\u5f8c\uff0c\u5e02\u5834\u4e0b\u4e00\u6b65\u7126\u9ede\u653e\u5728\u5982\u4f55\u300e\u7626\u5f97\u5065\u5eb7\u53c8\u597d\u770b<\/b>\u300f\uff0c\u56e0\u6b64\uff0c\u4e0b\u4e00\u4ee3\u7642\u6cd5\u5c07\u66f4\u95dc\u6ce8\u5982\u4f55\u63d0\u5347\u6e1b\u91cd\u6301\u4e45\u6027\u3001\u6e1b\u5c11\u66f4\u591a\u8102\u80aa\uff0c\u540c\u6642\u6539\u5584\u4ee3\u8b1d\u5065\u5eb7\uff0c\u9019\u6b63\u662f\u5168\u7403\u696d\u754c\u7a4d\u6975\u5c0b\u627e\u89e3\u65b9\u7684\u91cd\u8981\u8ab2\u984c\uff0c\u4e5f\u662f<\/b>CBL-514<\/b>\u6700\u5177\u50f9\u503c\u7684\u5dee\u7570\u5316\u6240\u5728<\/b>\u3002\u5f9eDr. Sharma\u6f14\u8b1b\u7d50\u675f\u5f8c\uff0c\u73fe\u5834 Q&A \u53cd\u61c9\u7684\u71b1\u70c8\uff0c\u4ee5\u53ca\u6703\u5f8c\u8207\u591a\u5bb6\u570b\u969b\u80a5\u80d6\u9818\u57df\u7522\u696d\u4ee3\u8868\u9032\u4e00\u6b65\u4ea4\u6d41\u53ef\u898b\uff0c\u696d\u754c\u9664\u4e86\u671f\u5f85 CBL-514 \u5c40\u90e8\u6e1b\u8102\u5728\u91ab\u7f8e\u5e02\u5834\u7684\u81e8\u5e8a\u767c\u5c55\uff0c\u5c0d\u5176\u672a\u4f86\u65bc\u80a5\u80d6\u8207\u4ee3\u8b1d\u5065\u5eb7\u9818\u57df\u7684\u6f5b\u5728\u61c9\u7528\uff0c\u4e5f\u5448\u73fe\u8d8a\u4f86\u8d8a\u71b1\u70c8\u7684\u95dc\u6ce8\u3002<\/b>\u300d<\/p>\n

    \u9664\u672c\u6b21 ECO 2026 \u53e3\u982d\u767c\u8868\u5916\uff0cCBL-514 \u8207 GLP-1R \u985e\u85e5\u7269\u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u6578\u64da\u4ea6\u5df2\u7372\u9078\u65bc6\u6708\u7684\u7f8e\u570b\u7cd6\u5c3f\u75c5\u5354\u6703\u5e74\u6703\uff08ADA 2026 Scientific Sessions\uff09\u767c\u8868\uff0c\u5c07\u6301\u7e8c\u64f4\u5927 CBL-514 \u65bc\u5168\u7403\u7cd6\u5c3f\u75c5\u3001\u80a5\u80d6\u8207\u4ee3\u8b1d\u91ab\u5b78\u9818\u57df\u4e4b\u570b\u969b\u4ee3\u8868\u6027\u3002<\/p>\n

    \u5eb7\u9708\u5c07\u6301\u7e8c\u6df1\u5316 CBL-514 \u8207 GLP-1R \u985e\u85e5\u7269\u4f75\u7528\u4e4b\u7814\u7a76\uff0c\u4e26\u65bc\u4eca\u5e74\u63a8\u9032\u4eba\u9ad4\u81e8\u5e8a\u8a66\u9a57\uff0c\u540c\u6642\u6301\u7e8c\u6df1\u5316 CBL-514 \u5168\u7403\u81e8\u5e8a\u958b\u767c\u7b56\u7565\u8207\u570b\u969b\u6388\u6b0a\u5e03\u5c40\u3002<\/p>\n

    *<\/b>\u95dc\u65bc<\/b>CBL-514 <\/b>
    CBL-514\u6ce8\u5c04\u5291\u662f\u5eb7\u9708\u751f\u6280\u81ea\u884c\u7814\u767c\u7684505(b)(1)\u5168\u65b0\u5c0f\u5206\u5b50\u65b0\u85e5\uff0c\u662f\u5168\u7403\u9996\u5275\u900f\u904e\u8a98\u5c0e\u8102\u80aa\u7d30\u80de\u51cb\u4ea1\u4f86\u7cbe\u6e96\u6e1b\u5c11\u6ce8\u5c04\u90e8\u4f4d\u8102\u80aa\uff0c\u6839\u64da\u5176\u5df2\u5b8c\u6210\u7684\u81e8\u5e8a\u8a66\u9a57\u7d50\u679c\uff0c\u7642\u6548\u512a\u7570\u8207\u624b\u8853\u76f8\u7576\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u4e0d\u6703\u9020\u6210\u5176\u4ed6\u7d30\u80de\u8207\u7d44\u7e54\u58de\u6b7b\u6216\u660e\u986f\u50b7\u5bb3\u3002<\/p>\n

    CBL-514\u5177\u6709\u591a\u9805\u9069\u61c9\u75c7\uff0c\u76ee\u524d\u9069\u61c9\u75c7\u5305\u542b\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa\uff08\u975e\u624b\u8853\u5c40\u90e8\u6e1b\u8102\uff09\u3001\u4e2d\/\u91cd\u5ea6\u6a58\u76ae\u7d44\u7e54\uff08cellulite\uff09\u7b49\uff0c\u540c\u6210\u4efd\u4e0d\u540c\u5291\u578b\u4e4b\u65b0\u85e5CBL-514D\u9069\u61c9\u75c7\u5305\u542b\u7f55\u898b\u75be\u75c5-\u7ac7\u6839\u6c0f\u75c7\uff08Dercum’s disease\uff09\u3002\u76ee\u524d\u70ba\u6b62\uff0c\u5168\u7403\u5df2\u5171\u6709544\u540d\u53d7\u8a66\u8005\u53c3\u8207CBL-514\u76f8\u95dc\u81e8\u5e8a\u8a66\u9a57\uff1b\u6839\u64da\u76ee\u524d\u5df2\u5b8c\u6210\u4e26\u53d6\u5f97\u7d71\u8a08\u7d50\u679c\u4e4b10\u9805\u81e8\u5e8a\u8a66\u7684\u4e3b\u8981\u7642\u6548\u6307\u6a19\u8207\u91cd\u8981\u6b21\u8981\u7642\u6548\u6307\u6a19\u7686\u5168\u90e8\u9054\u6a19\uff0c\u4e14\u85e5\u54c1\u5b89\u5168\u6027\u8207\u8010\u53d7\u5ea6\u826f\u597d\u3002CBL-514\u5728\u4e0d\u540c\u9069\u61c9\u75c7\u7686\u5c55\u73fe\u4e86\u512a\u7570\u4e14\u7cbe\u6e96\u7684\u7642\u6548\u8207\u826f\u597d\u5b89\u5168\u6027\uff0c\u4e26\u5728ITT\u6216FAS\u5206\u6790\u65cf\u7fa4\u7642\u6548\u7686\u5177\u6709\u51fa\u8272\u7684\u7d71\u8a08\u986f\u8457\u6027\u3002\u66f4\u591a\u95dc\u65bcCBL-514\u7684\u4ecb\u7d39\uff0c\u8acb\u62dc\u8a2a\u5eb7\u9708\u5b98\u7db2\uff1ahttps:\/\/www.caliwaybiopharma.com\/research\/15\/<\/a><\/p>\n

    *<\/b>\u95dc\u65bc\u5eb7\u9708<\/b>
    \u5eb7\u9708\u751f\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\u65bc2012<\/span>\u5e74\u5275\u7acb\uff0c\u81f4\u529b\u65bc\u958b\u767c\u80fd\u300c\u8d85\u8d8a\u73fe\u6709\u7642\u6cd5\uff0c\u6539\u8b8a\u5e02\u5834\u5275\u65b0\u300d\u7684\u65b0\u85e5\u7522\u54c1\uff0c\u5c07\u53f0\u7063\u5145\u6c9b\u7684\u65b0\u85e5\u7814\u767c\u91cf\u80fd\u767c\u63ee\u65bc\u5168\u7403\u751f\u91ab\u8207\u91ab\u7f8e\u7522\u696d\uff0c\u5df2\u65bc2024<\/span>\u5e7410\u67082\u65e5\u6b63\u5f0f\u639b\u724c\u4e0a\u5e02\u3002<\/p>\n

    *<\/b>\u8072\u660e<\/b>
    \u672c\u6587\u7ae0\u53ca\u7db2\u7ad9\u4e2d\u6240\u767c\u4f48\u4e4b\u76f8\u95dc\u8cc7\u6599\u542b\u6709\u9810\u6e2c\u6027\u6558\u8ff0\uff0c\u6b64\u985e\u6558\u8ff0\u662f\u57fa\u65bc\u73fe\u6cc1\u7684\u9810\u6e2c\u548c\u8a55\u4f30\u3002\u9019\u4e9b\u9810\u6e2c\u6027\u6558\u8ff0\u5c07\u53d7\u4e0d\u78ba\u5b9a\u6027\u3001\u98a8\u96aa\u8207\u5176\u4ed6\u975e\u672c\u516c\u53f8\u6240\u80fd\u638c\u63a7\u7b49\u56e0\u7d20\u5f71\u97ff\u3002\u60df\u4ecd\u5b58\u6709\u8a31\u591a\u56e0\u7d20\u53ef\u80fd\u4f7f\u4e8b\u4ef6\u7684\u767c\u5c55\u6216\u5176\u5be6\u969b\u7d50\u679c\u8207\u9810\u6e2c\u6027\u6558\u8ff0\u6709\u91cd\u5927\u5dee\u7570\u3002\u672c\u516c\u53f8\u4e0d\u8ca0\u4efb\u4f55\u66f4\u65b0\u6216\u4fee\u8a02\u4e4b\u8cac\u4efb\u3002<\/p>\n

    *<\/b>\u65b0\u805e\u806f\u7e6b
    <\/b>    ir@caliwaybiopharma.com<\/a>\u00a0<\/p>\n

    \n<\/p><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    \u5eb7\u9708\u9996\u5ea6\u4eae\u76f8ECO 2026\u53e3…<\/p>\n","protected":false},"author":16,"featured_media":436662,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-436661","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"\n\u5eb7\u9708\u9996\u767b ECO 2026 \u53e3\u982d\u767c\u8868 CBL-514 \u4f75\u7528 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u52d5\u7269\u6578\u64da \u5168\u8eab\u6027\u4ee3\u8b1d\u6548\u679c\u5438\u5f15\u570b\u969b\u5c08\u5bb6\u53ca\u5927\u85e5\u5ee0\u9ad8\u5ea6\u8208\u8da3 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831<\/title>\n<meta name=\"description\" content=\"\u5eb7\u9708\u9996\u5ea6\u4eae\u76f8ECO 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Semaglutide \u53ca Tirzepatide \u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u7d50\u679c\uff0c\u7d50\u679c\u986f\u793a\uff0cCBL-514 \u4f75\u7528 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u5f8c\uff0c\u65bc\u52d5\u7269\u5be6\u9a57\u4e2d\u5c55\u73fe\u56db\u9805\u5177\u4e92\u88dc\u3001\u5354\u540c\u6027\u7684\u61c9\u7528\u6f5b\u529b\uff1a \u66f4\u5f37\u7684\u6e1b\u91cd\u6548\u679c\uff1a\u4ee5\u8207Semaglutide\u4f75\u7528\u7814\u7a76\u70ba\u4f8b\uff0cCBL-514\u4f75\u7528\u7d44\u76f8\u8f03 Semaglutide \u55ae\u7528\u7d44\uff0c\u9ad4\u91cd\u4e0b\u964d\u5e45\u5ea6\u9032\u4e00\u6b65\u63d0\u534791.5%\u3002\u986f\u793a\u4f75\u7528\u7626\u7626\u91dd\u5177\u5099\u9032\u4e00\u6b65\u589e\u5f37\u9ad4\u91cd\u4e0b\u964d\u4e4b\u6f5b\u529b\u3002 \u66f4\u6301\u4e45\u7684\u505c\u85e5\u5f8c\u9ad4\u91cd\u7dad\u6301\uff1a\u4ee5 Tirzepatide \u7814\u7a76\u70ba\u4f8b\uff0cTirzepatide \u55ae\u7528\u7d44\u65bc\u505c\u85e5\u5f8c\u9ad4\u91cd\u56de\u5347\u5e45\u5ea6\u70ba55.9%\uff0c\u800cCBL-514 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\u53cd\u61c9\u7684\u71b1\u70c8\uff0c\u4ee5\u53ca\u6703\u5f8c\u8207\u591a\u5bb6\u570b\u969b\u80a5\u80d6\u9818\u57df\u7522\u696d\u4ee3\u8868\u9032\u4e00\u6b65\u4ea4\u6d41\u53ef\u898b\uff0c\u696d\u754c\u9664\u4e86\u671f\u5f85 CBL-514 \u5c40\u90e8\u6e1b\u8102\u5728\u91ab\u7f8e\u5e02\u5834\u7684\u81e8\u5e8a\u767c\u5c55\uff0c\u5c0d\u5176\u672a\u4f86\u65bc\u80a5\u80d6\u8207\u4ee3\u8b1d\u5065\u5eb7\u9818\u57df\u7684\u6f5b\u5728\u61c9\u7528\uff0c\u4e5f\u5448\u73fe\u8d8a\u4f86\u8d8a\u71b1\u70c8\u7684\u95dc\u6ce8\u3002\u300d \u9664\u672c\u6b21 ECO 2026 \u53e3\u982d\u767c\u8868\u5916\uff0cCBL-514 \u8207 GLP-1R \u985e\u85e5\u7269\u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u6578\u64da\u4ea6\u5df2\u7372\u9078\u65bc6\u6708\u7684\u7f8e\u570b\u7cd6\u5c3f\u75c5\u5354\u6703\u5e74\u6703\uff08ADA 2026 Scientific Sessions\uff09\u767c\u8868\uff0c\u5c07\u6301\u7e8c\u64f4\u5927 CBL-514 \u65bc\u5168\u7403\u7cd6\u5c3f\u75c5\u3001\u80a5\u80d6\u8207\u4ee3\u8b1d\u91ab\u5b78\u9818\u57df\u4e4b\u570b\u969b\u4ee3\u8868\u6027\u3002 \u5eb7\u9708\u5c07\u6301\u7e8c\u6df1\u5316 CBL-514 \u8207 GLP-1R \u985e\u85e5\u7269\u4f75\u7528\u4e4b\u7814\u7a76\uff0c\u4e26\u65bc\u4eca\u5e74\u63a8\u9032\u4eba\u9ad4\u81e8\u5e8a\u8a66\u9a57\uff0c\u540c\u6642\u6301\u7e8c\u6df1\u5316 CBL-514 \u5168\u7403\u81e8\u5e8a\u958b\u767c\u7b56\u7565\u8207\u570b\u969b\u6388\u6b0a\u5e03\u5c40\u3002 *\u95dc\u65bcCBL-514 CBL-514\u6ce8\u5c04\u5291\u662f\u5eb7\u9708\u751f\u6280\u81ea\u884c\u7814\u767c\u7684505(b)(1)\u5168\u65b0\u5c0f\u5206\u5b50\u65b0\u85e5\uff0c\u662f\u5168\u7403\u9996\u5275\u900f\u904e\u8a98\u5c0e\u8102\u80aa\u7d30\u80de\u51cb\u4ea1\u4f86\u7cbe\u6e96\u6e1b\u5c11\u6ce8\u5c04\u90e8\u4f4d\u8102\u80aa\uff0c\u6839\u64da\u5176\u5df2\u5b8c\u6210\u7684\u81e8\u5e8a\u8a66\u9a57\u7d50\u679c\uff0c\u7642\u6548\u512a\u7570\u8207\u624b\u8853\u76f8\u7576\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u4e0d\u6703\u9020\u6210\u5176\u4ed6\u7d30\u80de\u8207\u7d44\u7e54\u58de\u6b7b\u6216\u660e\u986f\u50b7\u5bb3\u3002 CBL-514\u5177\u6709\u591a\u9805\u9069\u61c9\u75c7\uff0c\u76ee\u524d\u9069\u61c9\u75c7\u5305\u542b\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa\uff08\u975e\u624b\u8853\u5c40\u90e8\u6e1b\u8102\uff09\u3001\u4e2d\/\u91cd\u5ea6\u6a58\u76ae\u7d44\u7e54\uff08cellulite\uff09\u7b49\uff0c\u540c\u6210\u4efd\u4e0d\u540c\u5291\u578b\u4e4b\u65b0\u85e5CBL-514D\u9069\u61c9\u75c7\u5305\u542b\u7f55\u898b\u75be\u75c5-\u7ac7\u6839\u6c0f\u75c7\uff08Dercum's disease\uff09\u3002\u76ee\u524d\u70ba\u6b62\uff0c\u5168\u7403\u5df2\u5171\u6709544\u540d\u53d7\u8a66\u8005\u53c3\u8207CBL-514\u76f8\u95dc\u81e8\u5e8a\u8a66\u9a57\uff1b\u6839\u64da\u76ee\u524d\u5df2\u5b8c\u6210\u4e26\u53d6\u5f97\u7d71\u8a08\u7d50\u679c\u4e4b10\u9805\u81e8\u5e8a\u8a66\u7684\u4e3b\u8981\u7642\u6548\u6307\u6a19\u8207\u91cd\u8981\u6b21\u8981\u7642\u6548\u6307\u6a19\u7686\u5168\u90e8\u9054\u6a19\uff0c\u4e14\u85e5\u54c1\u5b89\u5168\u6027\u8207\u8010\u53d7\u5ea6\u826f\u597d\u3002CBL-514\u5728\u4e0d\u540c\u9069\u61c9\u75c7\u7686\u5c55\u73fe\u4e86\u512a\u7570\u4e14\u7cbe\u6e96\u7684\u7642\u6548\u8207\u826f\u597d\u5b89\u5168\u6027\uff0c\u4e26\u5728ITT\u6216FAS\u5206\u6790\u65cf\u7fa4\u7642\u6548\u7686\u5177\u6709\u51fa\u8272\u7684\u7d71\u8a08\u986f\u8457\u6027\u3002\u66f4\u591a\u95dc\u65bcCBL-514\u7684\u4ecb\u7d39\uff0c\u8acb\u62dc\u8a2a\u5eb7\u9708\u5b98\u7db2\uff1ahttps:\/\/www.caliwaybiopharma.com\/research\/15\/ *\u95dc\u65bc\u5eb7\u9708\u5eb7\u9708\u751f\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\u65bc2012\u5e74\u5275\u7acb\uff0c\u81f4\u529b\u65bc\u958b\u767c\u80fd\u300c\u8d85\u8d8a\u73fe\u6709\u7642\u6cd5\uff0c\u6539\u8b8a\u5e02\u5834\u5275\u65b0\u300d\u7684\u65b0\u85e5\u7522\u54c1\uff0c\u5c07\u53f0\u7063\u5145\u6c9b\u7684\u65b0\u85e5\u7814\u767c\u91cf\u80fd\u767c\u63ee\u65bc\u5168\u7403\u751f\u91ab\u8207\u91ab\u7f8e\u7522\u696d\uff0c\u5df2\u65bc2024\u5e7410\u67082\u65e5\u6b63\u5f0f\u639b\u724c\u4e0a\u5e02\u3002 *\u8072\u660e\u672c\u6587\u7ae0\u53ca\u7db2\u7ad9\u4e2d\u6240\u767c\u4f48\u4e4b\u76f8\u95dc\u8cc7\u6599\u542b\u6709\u9810\u6e2c\u6027\u6558\u8ff0\uff0c\u6b64\u985e\u6558\u8ff0\u662f\u57fa\u65bc\u73fe\u6cc1\u7684\u9810\u6e2c\u548c\u8a55\u4f30\u3002\u9019\u4e9b\u9810\u6e2c\u6027\u6558\u8ff0\u5c07\u53d7\u4e0d\u78ba\u5b9a\u6027\u3001\u98a8\u96aa\u8207\u5176\u4ed6\u975e\u672c\u516c\u53f8\u6240\u80fd\u638c\u63a7\u7b49\u56e0\u7d20\u5f71\u97ff\u3002\u60df\u4ecd\u5b58\u6709\u8a31\u591a\u56e0\u7d20\u53ef\u80fd\u4f7f\u4e8b\u4ef6\u7684\u767c\u5c55\u6216\u5176\u5be6\u969b\u7d50\u679c\u8207\u9810\u6e2c\u6027\u6558\u8ff0\u6709\u91cd\u5927\u5dee\u7570\u3002\u672c\u516c\u53f8\u4e0d\u8ca0\u4efb\u4f55\u66f4\u65b0\u6216\u4fee\u8a02\u4e4b\u8cac\u4efb\u3002 *\u65b0\u805e\u806f\u7e6bir@caliwaybiopharma.com\u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=436661\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u5eb7\u9708\u9996\u767b ECO 2026 \u53e3\u982d\u767c\u8868 CBL-514 \u4f75\u7528 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u52d5\u7269\u6578\u64da \u5168\u8eab\u6027\u4ee3\u8b1d\u6548\u679c\u5438\u5f15\u570b\u969b\u5c08\u5bb6\u53ca\u5927\u85e5\u5ee0\u9ad8\u5ea6\u8208\u8da3 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u5eb7\u9708\u9996\u5ea6\u4eae\u76f8ECO 2026\u53e3\u982d\u767c\u8868\uff0c\u73fe\u5834\u53c3\u8207\u71b1\u7d61\uff0c\u5438\u5f15\u8d85\u904e300\u4f4d\u4f86\u81ea\u570b\u969b\u5927\u85e5\u5ee0\u3001\u81e8\u5e8a\u91ab\u5e2b\u53ca\u5c08\u5bb6\u5b78\u8005\u7b49\u7522\u696d\u4eba\u58eb\u8046\u807d\u3002 \u6b50\u6d32\u80a5\u80d6\u75c7\u5927\u6703\uff08ECO\uff09\u70ba\u5168\u7403\u80a5\u80d6\u8207\u4ee3\u8b1d\u91ab\u5b78\u9818\u57df\u5177\u91cd\u8981\u5f71\u97ff\u529b\u7684\u570b\u969b\u76db\u6703\u4e4b\u4e00\uff0c\u6bcf\u5e74\u532f\u805a\u4f86\u81ea\u8d85\u904e100\u500b\u570b\u5bb6\u3001\u903e4,000\u540d\u80a5\u80d6\u91ab\u5b78\u3001\u4ee3\u8b1d\u75be\u75c5\u8207\u9ad4\u91cd\u7ba1\u7406\u9818\u57df\u5c08\u5bb6\uff0c\u5206\u4eab\u6700\u65b0\u8da8\u52e2\u8207\u65b0\u85e5\u7814\u767c\u9032\u5c55\u3002\u8b1b\u8005 Dr. Sharma \u70ba\u5168\u7403\u5c07\u80a5\u80d6\u8996\u70ba\u300c\u6162\u6027\u75be\u75c5\u300d\u7684\u5148\u9a45\uff0c\u4ea6\u66fe\u53d7\u9080\u64d4\u4efb\u827e\u4f2f\u7dad\u3001\u963f\u65af\u7279\u6377\u5229\u5eb7\u3001\u767e\u9748\u4f73\u6bb7\u683c\u7ff0\u3001\u79ae\u4f86\u8207\u8afe\u548c\u8afe\u5fb7\u7b49\u8de8\u570b\u5927\u85e5\u5ee0\u5728\u80a5\u80d6\u91ab\u5b78\u9818\u57df\u7684\u79d1\u5b78\u9867\u554f\u8207\u8b1b\u8005\u3002 \u672c\u6b21\u53e3\u982d\u767c\u8868\u73fe\u5834\u53c3\u8207\u8e34\u8e8d\uff0c\u5171\u5438\u5f15\u8d85\u904e300\u4f4d\u807d\u773e\u53c3\u8207\uff0c\u5305\u62ec\u8de8\u570b\u85e5\u5ee0\u4ee3\u8868\u3001\u81e8\u5e8a\u91ab\u5e2b\u3001\u5c08\u5bb6\u5b78\u8005\u53ca\u7522\u696d\u4eba\u58eb\uff0c\u9032\u4e00\u6b65\u63d0\u5347 CBL-514 \u65bc\u570b\u969b\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u4e4b\u80fd\u898b\u5ea6\u3002 \u672c\u6b21\u767c\u8868\u7684\u7814\u7a76\u6db5\u84cb CBL-514 \u5206\u5225\u8207\u5169\u5927\u4e3b\u6d41 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269 Semaglutide \u53ca Tirzepatide \u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u7d50\u679c\uff0c\u7d50\u679c\u986f\u793a\uff0cCBL-514 \u4f75\u7528 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u5f8c\uff0c\u65bc\u52d5\u7269\u5be6\u9a57\u4e2d\u5c55\u73fe\u56db\u9805\u5177\u4e92\u88dc\u3001\u5354\u540c\u6027\u7684\u61c9\u7528\u6f5b\u529b\uff1a \u66f4\u5f37\u7684\u6e1b\u91cd\u6548\u679c\uff1a\u4ee5\u8207Semaglutide\u4f75\u7528\u7814\u7a76\u70ba\u4f8b\uff0cCBL-514\u4f75\u7528\u7d44\u76f8\u8f03 Semaglutide \u55ae\u7528\u7d44\uff0c\u9ad4\u91cd\u4e0b\u964d\u5e45\u5ea6\u9032\u4e00\u6b65\u63d0\u534791.5%\u3002\u986f\u793a\u4f75\u7528\u7626\u7626\u91dd\u5177\u5099\u9032\u4e00\u6b65\u589e\u5f37\u9ad4\u91cd\u4e0b\u964d\u4e4b\u6f5b\u529b\u3002 \u66f4\u6301\u4e45\u7684\u505c\u85e5\u5f8c\u9ad4\u91cd\u7dad\u6301\uff1a\u4ee5 Tirzepatide \u7814\u7a76\u70ba\u4f8b\uff0cTirzepatide \u55ae\u7528\u7d44\u65bc\u505c\u85e5\u5f8c\u9ad4\u91cd\u56de\u5347\u5e45\u5ea6\u70ba55.9%\uff0c\u800cCBL-514 \u4f75\u7528\u7d44\u9ad4\u91cd\u56de\u5347\u5e45\u5ea6\u50c525.2%\u3002\u986f\u793aCBL-514 \u4f75\u7528\u7626\u7626\u91dd\u65bc\u505c\u85e5\u5f8c\uff0c\u5177\u5099\u6e1b\u7de9\u9ad4\u91cd\u56de\u5347\u4e4b\u6f5b\u529b\u3002 \u66f4\u986f\u8457\u7684\u76ae\u4e0b\u8207\u5167\u81df\u8102\u80aa\u6e1b\u5c11\uff1a\u65bc GLP-1R \u985e\u85e5\u7269\u505c\u7528\u5f8c\uff0c CBL-514 \u4f75\u7528\u7d44\u53ef\u9032\u4e00\u6b65\u984d\u5916\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa182.5%\u8207\u5167\u81df\u8102\u80aa367.4%\u3002\u5177\u5099\u512a\u5316\u9ad4\u7d44\u6210\u4e4b\u6f5b\u529b\u3002 \u809d\u81df\u4ee3\u8b1d\u6307\u6a19\u6539\u5584\uff1a\u672c\u6b21 ECO \u53e3\u982d\u767c\u8868\u4ea6\u9996\u5ea6\u63ed\u793a CBL-514 \u4f75\u7528 Semaglutide \u5f8c\uff0c\u65bc\u809d\u81df\u4ee3\u8b1d\u76f8\u95dc\u6307\u6a19\u4e0a\u7684\u6539\u5584\u3002\u7d50\u679c\u986f\u793a\uff0c\u76f8\u8f03\u65bc\u5c0d\u7167\u7d44\uff0cCBL-514 \u4f75\u7528 Semaglutide \u7d44\u4e4b\u809d\u81df\u8102\u8cea\u542b\u91cf\u4e0b\u964d40.4%\uff0c\u809d\u81df\u81bd\u56fa\u9187\u4e0b\u964d52.7%\uff1b\u5728\u809d\u81df\u7d44\u7e54\u75c5\u7406\u5206\u6790\u4e2d\uff0c\u4ea6\u89c0\u5bdf\u5230\u8102\u80aa\u8b8a\u6027\u3001\u767c\u708e\u53ca\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u6d3b\u52d5\u5ea6\u8a55\u5206\uff08NAS score\uff09\u7b49\u809d\u81df\u50b7\u5bb3\u76f8\u95dc\u6307\u6a19\u6539\u5584\u3002\u6b64\u7d50\u679c\u986f\u793a\uff0cCBL-514 \u8207 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u4f75\u7528\uff0c\u5728\u52d5\u7269\u5be6\u9a57\u4e2d\u9664\u9ad4\u91cd\u7dad\u6301\u8207\u8102\u80aa\u6e1b\u5c11\u5916\uff0c\u4ea6\u5448\u73fe\u6539\u5584\u809d\u81df\u4ee3\u8b1d\u8207\u767c\u708e\u72c0\u614b\u4e4b\u6f5b\u5728\u79d1\u5b78\u610f\u7fa9\u3002 \u5eb7\u9708\u526f\u7e3d\u937e\u742d\u74a3\u8868\u793a\uff1a\u300c\u6211\u5011\u5f88\u69ae\u5e78\u7531 Dr. Sharma \u9019\u6a23\u5177\u570b\u969b\u5f71\u97ff\u529b\u7684\u80a5\u80d6\u91ab\u5b78\u6b0a\u5a01\uff0c\u65bc ECO 2026 \u5411\u5168\u7403\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u5c08\u5bb6\u767c\u8868 CBL-514 \u8207 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u6578\u64da\u3002\u672c\u6b21\u53e3\u982d\u767c\u8868\u73fe\u5834\u53c3\u8207\u5ea6\u9ad8\uff0c\u5438\u5f15\u8d85\u904e300\u4f4d\u807d\u773e\uff0c\u5305\u62ec\u8de8\u570b\u85e5\u5ee0\u4ee3\u8868\u3001\u81e8\u5e8a\u91ab\u5e2b\u3001\u5c08\u5bb6\u5b78\u8005\u53ca\u7522\u696d\u4eba\u58eb\uff0c\u6709\u52a9\u65bc\u63d0\u5347 CBL-514 \u5728\u570b\u969b\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u7684\u80fd\u898b\u5ea6\uff0c\u4e26\u6df1\u5316\u8207\u95dc\u9375\u6f5b\u5728\u5408\u4f5c\u5925\u4f34\u7684\u4ea4\u6d41\u3002\u300d \u937e\u742d\u74a3\u526f\u7e3d\u9032\u4e00\u6b65\u6307\u51fa\uff1a\u300c\u96a8\u8457 GLP-1R 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\u53cd\u61c9\u7684\u71b1\u70c8\uff0c\u4ee5\u53ca\u6703\u5f8c\u8207\u591a\u5bb6\u570b\u969b\u80a5\u80d6\u9818\u57df\u7522\u696d\u4ee3\u8868\u9032\u4e00\u6b65\u4ea4\u6d41\u53ef\u898b\uff0c\u696d\u754c\u9664\u4e86\u671f\u5f85 CBL-514 \u5c40\u90e8\u6e1b\u8102\u5728\u91ab\u7f8e\u5e02\u5834\u7684\u81e8\u5e8a\u767c\u5c55\uff0c\u5c0d\u5176\u672a\u4f86\u65bc\u80a5\u80d6\u8207\u4ee3\u8b1d\u5065\u5eb7\u9818\u57df\u7684\u6f5b\u5728\u61c9\u7528\uff0c\u4e5f\u5448\u73fe\u8d8a\u4f86\u8d8a\u71b1\u70c8\u7684\u95dc\u6ce8\u3002\u300d \u9664\u672c\u6b21 ECO 2026 \u53e3\u982d\u767c\u8868\u5916\uff0cCBL-514 \u8207 GLP-1R \u985e\u85e5\u7269\u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u6578\u64da\u4ea6\u5df2\u7372\u9078\u65bc6\u6708\u7684\u7f8e\u570b\u7cd6\u5c3f\u75c5\u5354\u6703\u5e74\u6703\uff08ADA 2026 Scientific Sessions\uff09\u767c\u8868\uff0c\u5c07\u6301\u7e8c\u64f4\u5927 CBL-514 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CBL-514\u5177\u6709\u591a\u9805\u9069\u61c9\u75c7\uff0c\u76ee\u524d\u9069\u61c9\u75c7\u5305\u542b\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa\uff08\u975e\u624b\u8853\u5c40\u90e8\u6e1b\u8102\uff09\u3001\u4e2d\/\u91cd\u5ea6\u6a58\u76ae\u7d44\u7e54\uff08cellulite\uff09\u7b49\uff0c\u540c\u6210\u4efd\u4e0d\u540c\u5291\u578b\u4e4b\u65b0\u85e5CBL-514D\u9069\u61c9\u75c7\u5305\u542b\u7f55\u898b\u75be\u75c5-\u7ac7\u6839\u6c0f\u75c7\uff08Dercum's disease\uff09\u3002\u76ee\u524d\u70ba\u6b62\uff0c\u5168\u7403\u5df2\u5171\u6709544\u540d\u53d7\u8a66\u8005\u53c3\u8207CBL-514\u76f8\u95dc\u81e8\u5e8a\u8a66\u9a57\uff1b\u6839\u64da\u76ee\u524d\u5df2\u5b8c\u6210\u4e26\u53d6\u5f97\u7d71\u8a08\u7d50\u679c\u4e4b10\u9805\u81e8\u5e8a\u8a66\u7684\u4e3b\u8981\u7642\u6548\u6307\u6a19\u8207\u91cd\u8981\u6b21\u8981\u7642\u6548\u6307\u6a19\u7686\u5168\u90e8\u9054\u6a19\uff0c\u4e14\u85e5\u54c1\u5b89\u5168\u6027\u8207\u8010\u53d7\u5ea6\u826f\u597d\u3002CBL-514\u5728\u4e0d\u540c\u9069\u61c9\u75c7\u7686\u5c55\u73fe\u4e86\u512a\u7570\u4e14\u7cbe\u6e96\u7684\u7642\u6548\u8207\u826f\u597d\u5b89\u5168\u6027\uff0c\u4e26\u5728ITT\u6216FAS\u5206\u6790\u65cf\u7fa4\u7642\u6548\u7686\u5177\u6709\u51fa\u8272\u7684\u7d71\u8a08\u986f\u8457\u6027\u3002\u66f4\u591a\u95dc\u65bcCBL-514\u7684\u4ecb\u7d39\uff0c\u8acb\u62dc\u8a2a\u5eb7\u9708\u5b98\u7db2\uff1ahttps:\/\/www.caliwaybiopharma.com\/research\/15\/ *\u95dc\u65bc\u5eb7\u9708\u5eb7\u9708\u751f\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\u65bc2012\u5e74\u5275\u7acb\uff0c\u81f4\u529b\u65bc\u958b\u767c\u80fd\u300c\u8d85\u8d8a\u73fe\u6709\u7642\u6cd5\uff0c\u6539\u8b8a\u5e02\u5834\u5275\u65b0\u300d\u7684\u65b0\u85e5\u7522\u54c1\uff0c\u5c07\u53f0\u7063\u5145\u6c9b\u7684\u65b0\u85e5\u7814\u767c\u91cf\u80fd\u767c\u63ee\u65bc\u5168\u7403\u751f\u91ab\u8207\u91ab\u7f8e\u7522\u696d\uff0c\u5df2\u65bc2024\u5e7410\u67082\u65e5\u6b63\u5f0f\u639b\u724c\u4e0a\u5e02\u3002 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CBL-514\u5177\u6709\u591a\u9805\u9069\u61c9\u75c7\uff0c\u76ee\u524d\u9069\u61c9\u75c7\u5305\u542b\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa\uff08\u975e\u624b\u8853\u5c40\u90e8\u6e1b\u8102\uff09\u3001\u4e2d\/\u91cd\u5ea6\u6a58\u76ae\u7d44\u7e54\uff08cellulite\uff09\u7b49\uff0c\u540c\u6210\u4efd\u4e0d\u540c\u5291\u578b\u4e4b\u65b0\u85e5CBL-514D\u9069\u61c9\u75c7\u5305\u542b\u7f55\u898b\u75be\u75c5-\u7ac7\u6839\u6c0f\u75c7\uff08Dercum's disease\uff09\u3002\u76ee\u524d\u70ba\u6b62\uff0c\u5168\u7403\u5df2\u5171\u6709544\u540d\u53d7\u8a66\u8005\u53c3\u8207CBL-514\u76f8\u95dc\u81e8\u5e8a\u8a66\u9a57\uff1b\u6839\u64da\u76ee\u524d\u5df2\u5b8c\u6210\u4e26\u53d6\u5f97\u7d71\u8a08\u7d50\u679c\u4e4b10\u9805\u81e8\u5e8a\u8a66\u7684\u4e3b\u8981\u7642\u6548\u6307\u6a19\u8207\u91cd\u8981\u6b21\u8981\u7642\u6548\u6307\u6a19\u7686\u5168\u90e8\u9054\u6a19\uff0c\u4e14\u85e5\u54c1\u5b89\u5168\u6027\u8207\u8010\u53d7\u5ea6\u826f\u597d\u3002CBL-514\u5728\u4e0d\u540c\u9069\u61c9\u75c7\u7686\u5c55\u73fe\u4e86\u512a\u7570\u4e14\u7cbe\u6e96\u7684\u7642\u6548\u8207\u826f\u597d\u5b89\u5168\u6027\uff0c\u4e26\u5728ITT\u6216FAS\u5206\u6790\u65cf\u7fa4\u7642\u6548\u7686\u5177\u6709\u51fa\u8272\u7684\u7d71\u8a08\u986f\u8457\u6027\u3002\u66f4\u591a\u95dc\u65bcCBL-514\u7684\u4ecb\u7d39\uff0c\u8acb\u62dc\u8a2a\u5eb7\u9708\u5b98\u7db2\uff1ahttps:\/\/www.caliwaybiopharma.com\/research\/15\/ *\u95dc\u65bc\u5eb7\u9708\u5eb7\u9708\u751f\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\u65bc2012\u5e74\u5275\u7acb\uff0c\u81f4\u529b\u65bc\u958b\u767c\u80fd\u300c\u8d85\u8d8a\u73fe\u6709\u7642\u6cd5\uff0c\u6539\u8b8a\u5e02\u5834\u5275\u65b0\u300d\u7684\u65b0\u85e5\u7522\u54c1\uff0c\u5c07\u53f0\u7063\u5145\u6c9b\u7684\u65b0\u85e5\u7814\u767c\u91cf\u80fd\u767c\u63ee\u65bc\u5168\u7403\u751f\u91ab\u8207\u91ab\u7f8e\u7522\u696d\uff0c\u5df2\u65bc2024\u5e7410\u67082\u65e5\u6b63\u5f0f\u639b\u724c\u4e0a\u5e02\u3002 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\u6b50\u6d32\u80a5\u80d6\u75c7\u5927\u6703\uff08ECO\uff09\u70ba\u5168\u7403\u80a5\u80d6\u8207\u4ee3\u8b1d\u91ab\u5b78\u9818\u57df\u5177\u91cd\u8981\u5f71\u97ff\u529b\u7684\u570b\u969b\u76db\u6703\u4e4b\u4e00\uff0c\u6bcf\u5e74\u532f\u805a\u4f86\u81ea\u8d85\u904e100\u500b\u570b\u5bb6\u3001\u903e4,000\u540d\u80a5\u80d6\u91ab\u5b78\u3001\u4ee3\u8b1d\u75be\u75c5\u8207\u9ad4\u91cd\u7ba1\u7406\u9818\u57df\u5c08\u5bb6\uff0c\u5206\u4eab\u6700\u65b0\u8da8\u52e2\u8207\u65b0\u85e5\u7814\u767c\u9032\u5c55\u3002\u8b1b\u8005 Dr. Sharma \u70ba\u5168\u7403\u5c07\u80a5\u80d6\u8996\u70ba\u300c\u6162\u6027\u75be\u75c5\u300d\u7684\u5148\u9a45\uff0c\u4ea6\u66fe\u53d7\u9080\u64d4\u4efb\u827e\u4f2f\u7dad\u3001\u963f\u65af\u7279\u6377\u5229\u5eb7\u3001\u767e\u9748\u4f73\u6bb7\u683c\u7ff0\u3001\u79ae\u4f86\u8207\u8afe\u548c\u8afe\u5fb7\u7b49\u8de8\u570b\u5927\u85e5\u5ee0\u5728\u80a5\u80d6\u91ab\u5b78\u9818\u57df\u7684\u79d1\u5b78\u9867\u554f\u8207\u8b1b\u8005\u3002 \u672c\u6b21\u53e3\u982d\u767c\u8868\u73fe\u5834\u53c3\u8207\u8e34\u8e8d\uff0c\u5171\u5438\u5f15\u8d85\u904e300\u4f4d\u807d\u773e\u53c3\u8207\uff0c\u5305\u62ec\u8de8\u570b\u85e5\u5ee0\u4ee3\u8868\u3001\u81e8\u5e8a\u91ab\u5e2b\u3001\u5c08\u5bb6\u5b78\u8005\u53ca\u7522\u696d\u4eba\u58eb\uff0c\u9032\u4e00\u6b65\u63d0\u5347 CBL-514 \u65bc\u570b\u969b\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u4e4b\u80fd\u898b\u5ea6\u3002 \u672c\u6b21\u767c\u8868\u7684\u7814\u7a76\u6db5\u84cb CBL-514 \u5206\u5225\u8207\u5169\u5927\u4e3b\u6d41 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269 Semaglutide \u53ca Tirzepatide \u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u7d50\u679c\uff0c\u7d50\u679c\u986f\u793a\uff0cCBL-514 \u4f75\u7528 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u5f8c\uff0c\u65bc\u52d5\u7269\u5be6\u9a57\u4e2d\u5c55\u73fe\u56db\u9805\u5177\u4e92\u88dc\u3001\u5354\u540c\u6027\u7684\u61c9\u7528\u6f5b\u529b\uff1a 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\u985e\u85e5\u7269\u505c\u7528\u5f8c\uff0c CBL-514 \u4f75\u7528\u7d44\u53ef\u9032\u4e00\u6b65\u984d\u5916\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa182.5%\u8207\u5167\u81df\u8102\u80aa367.4%\u3002\u5177\u5099\u512a\u5316\u9ad4\u7d44\u6210\u4e4b\u6f5b\u529b\u3002 \u809d\u81df\u4ee3\u8b1d\u6307\u6a19\u6539\u5584\uff1a\u672c\u6b21 ECO \u53e3\u982d\u767c\u8868\u4ea6\u9996\u5ea6\u63ed\u793a CBL-514 \u4f75\u7528 Semaglutide \u5f8c\uff0c\u65bc\u809d\u81df\u4ee3\u8b1d\u76f8\u95dc\u6307\u6a19\u4e0a\u7684\u6539\u5584\u3002\u7d50\u679c\u986f\u793a\uff0c\u76f8\u8f03\u65bc\u5c0d\u7167\u7d44\uff0cCBL-514 \u4f75\u7528 Semaglutide \u7d44\u4e4b\u809d\u81df\u8102\u8cea\u542b\u91cf\u4e0b\u964d40.4%\uff0c\u809d\u81df\u81bd\u56fa\u9187\u4e0b\u964d52.7%\uff1b\u5728\u809d\u81df\u7d44\u7e54\u75c5\u7406\u5206\u6790\u4e2d\uff0c\u4ea6\u89c0\u5bdf\u5230\u8102\u80aa\u8b8a\u6027\u3001\u767c\u708e\u53ca\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u6d3b\u52d5\u5ea6\u8a55\u5206\uff08NAS score\uff09\u7b49\u809d\u81df\u50b7\u5bb3\u76f8\u95dc\u6307\u6a19\u6539\u5584\u3002\u6b64\u7d50\u679c\u986f\u793a\uff0cCBL-514 \u8207 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u4f75\u7528\uff0c\u5728\u52d5\u7269\u5be6\u9a57\u4e2d\u9664\u9ad4\u91cd\u7dad\u6301\u8207\u8102\u80aa\u6e1b\u5c11\u5916\uff0c\u4ea6\u5448\u73fe\u6539\u5584\u809d\u81df\u4ee3\u8b1d\u8207\u767c\u708e\u72c0\u614b\u4e4b\u6f5b\u5728\u79d1\u5b78\u610f\u7fa9\u3002 \u5eb7\u9708\u526f\u7e3d\u937e\u742d\u74a3\u8868\u793a\uff1a\u300c\u6211\u5011\u5f88\u69ae\u5e78\u7531 Dr. Sharma \u9019\u6a23\u5177\u570b\u969b\u5f71\u97ff\u529b\u7684\u80a5\u80d6\u91ab\u5b78\u6b0a\u5a01\uff0c\u65bc ECO 2026 \u5411\u5168\u7403\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u5c08\u5bb6\u767c\u8868 CBL-514 \u8207 GLP-1R 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\u985e\u85e5\u7269\u505c\u7528\u5f8c\uff0c CBL-514 \u4f75\u7528\u7d44\u53ef\u9032\u4e00\u6b65\u984d\u5916\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa182.5%\u8207\u5167\u81df\u8102\u80aa367.4%\u3002\u5177\u5099\u512a\u5316\u9ad4\u7d44\u6210\u4e4b\u6f5b\u529b\u3002 \u809d\u81df\u4ee3\u8b1d\u6307\u6a19\u6539\u5584\uff1a\u672c\u6b21 ECO \u53e3\u982d\u767c\u8868\u4ea6\u9996\u5ea6\u63ed\u793a CBL-514 \u4f75\u7528 Semaglutide \u5f8c\uff0c\u65bc\u809d\u81df\u4ee3\u8b1d\u76f8\u95dc\u6307\u6a19\u4e0a\u7684\u6539\u5584\u3002\u7d50\u679c\u986f\u793a\uff0c\u76f8\u8f03\u65bc\u5c0d\u7167\u7d44\uff0cCBL-514 \u4f75\u7528 Semaglutide \u7d44\u4e4b\u809d\u81df\u8102\u8cea\u542b\u91cf\u4e0b\u964d40.4%\uff0c\u809d\u81df\u81bd\u56fa\u9187\u4e0b\u964d52.7%\uff1b\u5728\u809d\u81df\u7d44\u7e54\u75c5\u7406\u5206\u6790\u4e2d\uff0c\u4ea6\u89c0\u5bdf\u5230\u8102\u80aa\u8b8a\u6027\u3001\u767c\u708e\u53ca\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u6d3b\u52d5\u5ea6\u8a55\u5206\uff08NAS score\uff09\u7b49\u809d\u81df\u50b7\u5bb3\u76f8\u95dc\u6307\u6a19\u6539\u5584\u3002\u6b64\u7d50\u679c\u986f\u793a\uff0cCBL-514 \u8207 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u4f75\u7528\uff0c\u5728\u52d5\u7269\u5be6\u9a57\u4e2d\u9664\u9ad4\u91cd\u7dad\u6301\u8207\u8102\u80aa\u6e1b\u5c11\u5916\uff0c\u4ea6\u5448\u73fe\u6539\u5584\u809d\u81df\u4ee3\u8b1d\u8207\u767c\u708e\u72c0\u614b\u4e4b\u6f5b\u5728\u79d1\u5b78\u610f\u7fa9\u3002 \u5eb7\u9708\u526f\u7e3d\u937e\u742d\u74a3\u8868\u793a\uff1a\u300c\u6211\u5011\u5f88\u69ae\u5e78\u7531 Dr. Sharma \u9019\u6a23\u5177\u570b\u969b\u5f71\u97ff\u529b\u7684\u80a5\u80d6\u91ab\u5b78\u6b0a\u5a01\uff0c\u65bc ECO 2026 \u5411\u5168\u7403\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u5c08\u5bb6\u767c\u8868 CBL-514 \u8207 GLP-1R \u985e\u6e1b\u91cd\u85e5\u7269\u4f75\u7528\u4e4b\u52d5\u7269\u5be6\u9a57\u6578\u64da\u3002\u672c\u6b21\u53e3\u982d\u767c\u8868\u73fe\u5834\u53c3\u8207\u5ea6\u9ad8\uff0c\u5438\u5f15\u8d85\u904e300\u4f4d\u807d\u773e\uff0c\u5305\u62ec\u8de8\u570b\u85e5\u5ee0\u4ee3\u8868\u3001\u81e8\u5e8a\u91ab\u5e2b\u3001\u5c08\u5bb6\u5b78\u8005\u53ca\u7522\u696d\u4eba\u58eb\uff0c\u6709\u52a9\u65bc\u63d0\u5347 CBL-514 \u5728\u570b\u969b\u80a5\u80d6\u8207\u4ee3\u8b1d\u9818\u57df\u7684\u80fd\u898b\u5ea6\uff0c\u4e26\u6df1\u5316\u8207\u95dc\u9375\u6f5b\u5728\u5408\u4f5c\u5925\u4f34\u7684\u4ea4\u6d41\u3002\u300d \u937e\u742d\u74a3\u526f\u7e3d\u9032\u4e00\u6b65\u6307\u51fa\uff1a\u300c\u96a8\u8457 GLP-1R 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CBL-514\u6ce8\u5c04\u5291\u662f\u5eb7\u9708\u751f\u6280\u81ea\u884c\u7814\u767c\u7684505(b)(1)\u5168\u65b0\u5c0f\u5206\u5b50\u65b0\u85e5\uff0c\u662f\u5168\u7403\u9996\u5275\u900f\u904e\u8a98\u5c0e\u8102\u80aa\u7d30\u80de\u51cb\u4ea1\u4f86\u7cbe\u6e96\u6e1b\u5c11\u6ce8\u5c04\u90e8\u4f4d\u8102\u80aa\uff0c\u6839\u64da\u5176\u5df2\u5b8c\u6210\u7684\u81e8\u5e8a\u8a66\u9a57\u7d50\u679c\uff0c\u7642\u6548\u512a\u7570\u8207\u624b\u8853\u76f8\u7576\u4e14\u5b89\u5168\u6027\u826f\u597d\uff0c\u4e0d\u6703\u9020\u6210\u5176\u4ed6\u7d30\u80de\u8207\u7d44\u7e54\u58de\u6b7b\u6216\u660e\u986f\u50b7\u5bb3\u3002 CBL-514\u5177\u6709\u591a\u9805\u9069\u61c9\u75c7\uff0c\u76ee\u524d\u9069\u61c9\u75c7\u5305\u542b\u6e1b\u5c11\u76ae\u4e0b\u8102\u80aa\uff08\u975e\u624b\u8853\u5c40\u90e8\u6e1b\u8102\uff09\u3001\u4e2d\/\u91cd\u5ea6\u6a58\u76ae\u7d44\u7e54\uff08cellulite\uff09\u7b49\uff0c\u540c\u6210\u4efd\u4e0d\u540c\u5291\u578b\u4e4b\u65b0\u85e5CBL-514D\u9069\u61c9\u75c7\u5305\u542b\u7f55\u898b\u75be\u75c5-\u7ac7\u6839\u6c0f\u75c7\uff08Dercum's disease\uff09\u3002\u76ee\u524d\u70ba\u6b62\uff0c\u5168\u7403\u5df2\u5171\u6709544\u540d\u53d7\u8a66\u8005\u53c3\u8207CBL-514\u76f8\u95dc\u81e8\u5e8a\u8a66\u9a57\uff1b\u6839\u64da\u76ee\u524d\u5df2\u5b8c\u6210\u4e26\u53d6\u5f97\u7d71\u8a08\u7d50\u679c\u4e4b10\u9805\u81e8\u5e8a\u8a66\u7684\u4e3b\u8981\u7642\u6548\u6307\u6a19\u8207\u91cd\u8981\u6b21\u8981\u7642\u6548\u6307\u6a19\u7686\u5168\u90e8\u9054\u6a19\uff0c\u4e14\u85e5\u54c1\u5b89\u5168\u6027\u8207\u8010\u53d7\u5ea6\u826f\u597d\u3002CBL-514\u5728\u4e0d\u540c\u9069\u61c9\u75c7\u7686\u5c55\u73fe\u4e86\u512a\u7570\u4e14\u7cbe\u6e96\u7684\u7642\u6548\u8207\u826f\u597d\u5b89\u5168\u6027\uff0c\u4e26\u5728ITT\u6216FAS\u5206\u6790\u65cf\u7fa4\u7642\u6548\u7686\u5177\u6709\u51fa\u8272\u7684\u7d71\u8a08\u986f\u8457\u6027\u3002\u66f4\u591a\u95dc\u65bcCBL-514\u7684\u4ecb\u7d39\uff0c\u8acb\u62dc\u8a2a\u5eb7\u9708\u5b98\u7db2\uff1ahttps:\/\/www.caliwaybiopharma.com\/research\/15\/ *\u95dc\u65bc\u5eb7\u9708\u5eb7\u9708\u751f\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\u65bc2012\u5e74\u5275\u7acb\uff0c\u81f4\u529b\u65bc\u958b\u767c\u80fd\u300c\u8d85\u8d8a\u73fe\u6709\u7642\u6cd5\uff0c\u6539\u8b8a\u5e02\u5834\u5275\u65b0\u300d\u7684\u65b0\u85e5\u7522\u54c1\uff0c\u5c07\u53f0\u7063\u5145\u6c9b\u7684\u65b0\u85e5\u7814\u767c\u91cf\u80fd\u767c\u63ee\u65bc\u5168\u7403\u751f\u91ab\u8207\u91ab\u7f8e\u7522\u696d\uff0c\u5df2\u65bc2024\u5e7410\u67082\u65e5\u6b63\u5f0f\u639b\u724c\u4e0a\u5e02\u3002 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