{"id":428336,"date":"2026-04-20T20:18:00","date_gmt":"2026-04-20T12:18:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=428336"},"modified":"2026-04-20T20:18:00","modified_gmt":"2026-04-20T12:18:00","slug":"2026-aacr%ef%bc%9a%e6%98%93%e6%85%95%e5%b3%b0%e7%94%9f%e7%89%a9imv102%e9%ab%94%e5%85%a7car-t%e5%af%a6%e7%8f%be%e6%8c%81%e4%b9%85%e8%85%ab%e7%98%a4%e6%8e%a7%e5%88%b6%ef%bc%8c%e8%87%a8%e5%ba%8a%e5%89%8d","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=428336","title":{"rendered":"2026 AACR\uff1a\u6613\u6155\u5cf0\u751f\u7269IMV102\u9ad4\u5167CAR-T\u5be6\u73fe\u6301\u4e45\u816b\u7624\u63a7\u5236\uff0c\u81e8\u5e8a\u524d\u6578\u64da\u767c\u4f48"},"content":{"rendered":"<div>\n<p id=\"temp_ReleaseStart\"><span class=\"legendSpanClass\">\u4e0a\u6d77<\/span><span class=\"legendSpanClass\">2026\u5e744\u670820\u65e5<\/span> <span>\/\u7f8e\u901a\u793e\/ &#8212; \u8fd1\u65e5\uff0c\u6613\u6155\u5cf0\u751f\u7269\u5728<\/span><span>2026 AACR<\/span><span>\u5e74\u6703\u4e0a\u516c\u4f48\u4e86\u5176\u57fa\u65bc\u81ea\u7814<\/span><span>iMAGIC<\/span><span>\u5e73\u81fa\u958b\u767c\u7684\u9776\u5411<\/span><span>BCMA<\/span><span>\u9ad4\u5167<\/span><span>CAR-T<\/span><span>\u5019\u9078\u7642\u6cd5<\/span><span>IMV102<\/span><span>\u7684\u6700\u65b0\u81e8\u5e8a\u524d\u7814\u7a76\u6210\u679c\u3002\u8a72\u7814\u7a76\u986f\u793a\uff0c<\/span><span>IMV102<\/span><span>\u5728\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u6a21\u578b\u4e2d\u5be6\u73fe\u4e86\u6301\u4e45\u4e14\u986f\u8457\u7684\u6297\u816b\u7624\u6d3b\u6027\uff0c\u70ba\u7a81\u7834\u50b3\u7d71<\/span><span>CAR-T<\/span><span>\u7642\u6cd5\u7684\u53ef\u53ca\u6027\u74f6\u9838\u63d0\u4f9b\u4e86\u5168\u65b0\u8def\u5f91\u3002<\/span><\/p>\n<p class=\"prntaj\"><span>\u81ea\u9ad4<\/span><span>CAR-T<\/span><span>\u7642\u6cd5\u5728\u8840\u6db2\u816b\u7624\u9818\u57df\u53d6\u5f97\u4e86\u7a81\u7834\u6027\u9032\u5c55\uff0c\u4f46\u5176\u8907\u96dc\u7684\u500b\u9ad4\u5316\u88fd\u5099\u6d41\u7a0b\u548c\u9ad8\u6602\u6210\u672c\uff0c\u9650\u5236\u4e86\u5176\u66f4\u5ee3\u6cdb\u7684\u81e8\u5e8a\u61c9\u7528\u3002\u91dd\u5c0d\u9019\u4e00\u884c\u696d\u75db\u9ede\uff0c\u6613\u6155\u5cf0\u751f\u7269\u81ea\u4e3b\u958b\u767c\u4e86<\/span><span>iMAGIC<\/span><span>\u5e73\u81fa\u2014\u2014\u4e00\u7a2e\u57fa\u65bc\u6162\u75c5\u6bd2\u8f09\u9ad4\u7684\u9ad4\u5167<\/span><span>CAR-T<\/span><span>\u6280\u8853\u5e73\u81fa\u3002\u8a72\u8f09\u9ad4\u8868\u9762\u8986\u84cb\u6709\u7a81\u8b8a\u578b<\/span><span>MxV<\/span><span>\u7cd6\u86cb\u767d\uff08<\/span><span>MxV-G-mut<\/span><span>\uff09\uff0c\u901a\u904e\u7a81\u8b8a\u6d88\u9664\u5176\u53d7\u9ad4\u7d50\u5408\u80fd\u529b\uff0c\u4e26\u4fdd\u7559\u5176\u819c\u878d\u5408\u7684\u6d3b\u6027\uff1b\u540c\u6642\uff0c\u8f09\u9ad4\u6574\u5408\u4e86\u65b0\u4e00\u4ee3<\/span><span>T<\/span><span>\u7d30\u80de\u9776\u5411\u6a21\u584a<\/span><span>TCM3<\/span><span>\uff0c\u80fd\u5920\u9ad8\u7279\u7570\u6027\u8b58\u5225\u4e26\u7d50\u5408<\/span><span>T<\/span><span>\u7d30\u80de\u8868\u9762\u53d7\u9ad4\uff0c\u5f9e\u800c\u5be6\u73fe\u5c0d<\/span><span>T<\/span><span>\u7d30\u80de\u7684\u9ad8\u6548\u8f49\u5c0e\u3002<\/span><\/p>\n<p class=\"prntaj\"><span>\u57fa\u65bc<\/span><span>iMAGIC<\/span><span>\u5e73\u81fa\u958b\u767c\u7684<\/span><span>IMV102<\/span><span>\u662f\u4e00\u6b3e\u9776\u5411<\/span><span>BCMA<\/span><span>\u7684\u9ad4\u5167<\/span><span>CAR-T<\/span><span>\u5019\u9078\u7642\u6cd5\uff0c\u7528\u65bc\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u6cbb\u7642\u3002\u5728\u672c\u6b21\u7814\u7a76\u4e2d\uff0c<\/span><span>IMV102<\/span><span>\u5728\u591a\u7a2e\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u6a21\u578b\u4e2d\u5c55\u73fe\u51fa\u986f\u8457\u4e14\u6301\u4e45\u7684\u6297\u816b\u7624\u6d3b\u6027\uff0c\u4e26\u5177\u5099\u826f\u597d\u7684\u5b89\u5168\u6027\u7279\u5fb5\uff1a<\/span><\/p>\n<p class=\"prntaj\"><span>\u5728\u9ad4\u5916\u7814\u7a76\u4e2d\uff0c<\/span><span>IMV102<\/span><span>\u5c55\u73fe\u51fa\u5c0d<\/span><span>T<\/span><span>\u7d30\u80de\u7684\u9ad8\u5ea6\u7279\u7570\u6027\u8f49\u5c0e\u80fd\u529b\uff0c\u5728<\/span><span>Jurkat<\/span><span>\u7b49<\/span><span>T<\/span><span>\u7d30\u80de\u7cfb\u4e2d\u5be6\u73fe\u9ad8\u6548\u8f49\u5c0e\uff0c\u800c\u5728\u975e\u76ee\u6a19\u7d30\u80de\uff08\u5982\u809d\u7d30\u80de\u53ca<\/span><span>Kupffer<\/span><span>\u7d30\u80de\uff09\u4e2d\u672a\u6aa2\u6e2c\u5230\u986f\u8457\u8f49\u5c0e\uff0c\u9ad4\u73fe\u51fa\u826f\u597d\u7684\u9776\u5411\u7279\u7570\u6027\u3002\u6b64\u5916\uff0c<\/span><span>IMV102<\/span><span>\u751f\u6210\u7684<\/span><span>CAR-T<\/span><span>\u7d30\u80de\u5728\u8207<\/span><span>NCI-H929<\/span><span>\u9aa8\u9ad3\u7624\u7d30\u80de\u5171\u57f9\u990a\u6642\uff0c\u8868\u73fe\u51fa\u5f37\u6548\u7d30\u80de\u6bd2\u4f5c\u7528\uff0c\u4e26\u4f34\u96a8<\/span><span>IFN-<\/span><span>\u03b3\u986f\u8457\u4e0a\u8abf\uff0c\u9a57\u8b49\u4e86\u5176\u514d\u75ab\u6d3b\u6027\u3002<\/span><\/p>\n<p class=\"prntaj\"><span>\u5728\u9ad4\u5167\u7814\u7a76\u4e2d\uff0c<\/span><span>IMV102<\/span><span>\u5728\u5169\u7a2e\u591a\u767c\u6027\u9aa8\u9ad3\u7624\u7570\u7a2e\u79fb\u690d\u5c0f\u9f20\u6a21\u578b\uff08<\/span><span>H929-Luc<\/span><span>\u548c<\/span><span>MM.1S-Luc<\/span><span>\uff0c\u4eba<\/span><span>PBMC<\/span><span>\u91cd\u5efa\uff09\u4e2d\u6210\u529f\u8a98\u5c0e<\/span><span>CAR-T<\/span><span>\u7d30\u80de\u9ad4\u5167\u751f\u6210\uff0c\u4e26\u5be6\u73fe\u986f\u8457\u4e14\u6301\u4e45\u7684\u816b\u7624\u6291\u5236\u3002\u7814\u7a76\u671f\u9593\uff0c\u816b\u7624\u8ca0\u8377\u986f\u8457\u964d\u4f4e\uff1b\u540c\u6642\uff0c\u52d5\u7269\u9ad4\u91cd\u4fdd\u6301\u7a69\u5b9a\uff0c\u672a\u89c0\u5bdf\u5230\u660e\u986f\u5b89\u5168\u6027\u4fe1\u865f\uff1b<\/span><span>CAR-T<\/span><span>\u7d30\u80de\u64f4\u589e\u53ca\u8840\u6f3f<\/span><span>IFN-<\/span><span>\u03b3\u6c34\u5e73\u5747\u8655\u65bc\u53ef\u63a7\u7bc4\u570d\u5167\uff0c\u9ad4\u73fe\u51fa\u514d\u75ab\u6d3b\u6027\u8207\u5b89\u5168\u6027\u7684\u826f\u597d\u5e73\u8861\u3002<\/span><\/p>\n<p class=\"prntaj\"><span>\u6613\u6155\u5cf0\u751f\u7269\u8463\u4e8b\u9577<\/span><span>&amp;CEO<\/span><span>\u5b6b\u654f\u654f\u535a\u58eb\u8868\u793a\uff1a\u300c<\/span><span>IMV102<\/span><span>\u7684\u7a4d\u6975\u9032\u5c55\u9032\u4e00\u6b65\u9a57\u8b49\u4e86\u516c\u53f8\u300e\u9ad4\u5916<\/span><span>CAR-T + <\/span><span>\u9ad4\u5167<\/span><span>CAR-T\u300f<\/span><span>\u96d9\u5f15\u64ce\u6230\u7565\u7684\u524d\u77bb\u6027\u8207\u53ef\u884c\u6027\u3002\u9ad4\u5167<\/span><span>CAR-T<\/span><span>\u6709\u671b\u986f\u8457\u63d0\u5347\u7d30\u80de\u6cbb\u7642\u7684\u53ef\u53ca\u6027\uff0c\u63a8\u52d5<\/span><span>CAR-T<\/span><span>\u5f9e\u300e\u5b9a\u5236\u5316\u6cbb\u7642\u300f\u9081\u5411\u300e\u898f\u6a21\u5316\u61c9\u7528\u300f\u3002\u672a\u4f86\uff0c\u516c\u53f8\u5c07\u6301\u7e8c\u63a8\u9032<\/span><span>IMV102<\/span><span>\u7684\u81e8\u5e8a\u8f49\u5316\uff0c\u4e26\u52a0\u901f<\/span><span>iMAGIC<\/span><span>\u5e73\u81fa\u5728\u816b\u7624\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4e2d\u7684\u62d3\u5c55\u3002\u300d<\/span><\/p>\n<p class=\"prntaj\"><b><span>\u95dc\u65bc\u6613\u6155\u5cf0\u751f\u7269<\/span><\/b><\/p>\n<p class=\"prntaj\"><span>\u6613\u6155\u5cf0\u751f\u7269\u6210\u7acb\u65bc<\/span><span>2020<\/span><span>\u5e74\uff0c\u81f4\u529b\u65bc\u70ba\u5168\u7403\u764c\u75c7\u53ca\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u60a3\u8005\u63d0\u4f9b\u53ef\u53ca\u7684\u5275\u65b0\u7642\u6cd5\u3002\u6838\u5fc3\u5718\u968a\u64c1\u6709\u63a8\u52d5\u4e2d\u570b\u9996\u500b<\/span><span>CAR-T<\/span><span>\u85e5\u54c1\u4e0a\u5e02\u7684\u7522\u696d\u5316\u7d93\u9a57\u3002\u516c\u53f8\u69cb\u5efa\u4e86\u9ad4\u5916\u8207\u9ad4\u5167<\/span><span>CAR-T\u300c<\/span><span>\u96d9\u5f15\u64ce\u300d\u6a21\u5f0f\uff1a\u6838\u5fc3\u7522\u54c1<\/span><span>IMC002<\/span><span>\uff08<\/span><span>CLDN18.2 CAR-T<\/span><span>\uff09\u5df2\u9032\u5165\u4e2d\u570b<\/span><span>III<\/span><span>\u671f\u95dc\u9375\u81e8\u5e8a\u8a66\u9a57\uff1b<\/span><span>IMC001<\/span><span>\uff08<\/span><span>EpCAM CAR-T<\/span><span>\uff09\u70ba\u5168\u7403\u9996\u500b\u7372\u4e2d\u7f8e\u96d9\u5831<\/span><span>IND<\/span><span>\u6279\u51c6\u7684\u9776\u5411<\/span><span>EpCAM CAR-T<\/span><span>\u7522\u54c1\uff0c\u73fe\u6b63\u958b\u5c55\u4e2d\u570b<\/span><span>I\/IIa<\/span><span>\u671f\u7c43\u5f0f\u81e8\u5e8a\u8a66\u9a57\u3002\u9ad4\u5167<\/span><span>CAR-T<\/span><span>\u7ba1\u7dda\u8986\u84cb\u8840\u6db2\u7624\u3001\u5be6\u9ad4\u7624\u53ca\u81ea\u514d\u75be\u75c5\uff0c\u5176\u4e2d<\/span><span>IMV101<\/span><span>\u5df2\u9032\u5165<\/span><span>IIT<\/span><span>\u7814\u7a76\u968e\u6bb5\u3002\u516c\u53f8\u64c1\u6709<\/span><span>Peri Cruiser\u00ae<\/span><span>\u3001<\/span><span>SNR<\/span><span>\u3001<\/span><span>T-Booster<\/span><span>\u548c<\/span><span>SolidGuard<\/span><span>\u7b49\u591a\u6b3e\u5275\u65b0\u6280\u8853\u5e73\u81fa\uff0c<\/span><span>FOCO-CAR<\/span><span>\u751f\u7522\u5de5\u85dd\u5e73\u81fa\uff0c\u53ca<\/span><span>iMAGIC<\/span><span>\u9ad4\u5167<\/span><span>CAR-T<\/span><span>\u5e73\u81fa\u3002<\/span><\/p>\n<p class=\"prntaj\"><span>\u66f4\u591a\u4fe1\u606f\u8acb\u8a2a\u554f\uff1a<\/span><a href=\"http:\/\/www.immunofoco.com\/\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\"><span>www.immunofoco.com<\/span><\/a><\/p>\n<p class=\"prntaj\"><b><span>\u524d\u77bb\u6027\u8072\u660e<\/span><\/b><\/p>\n<p class=\"prntaj\"><span>\u672c\u65b0\u805e\u7a3f\u6240\u8f09\u5167\u5bb9\u5305\u542b\u82e5\u5e72\u524d\u77bb\u6027\u9673\u8ff0\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u65bc\u6709\u95dc\u516c\u53f8\u5019\u9078\u7522\u54c1<\/span><span>IMV102<\/span><span>\u7684\u6f5b\u5728\u7642\u6548\u3001\u5b89\u5168\u6027\u53ca\u81e8\u5e8a\u958b\u767c\u9032\u5c55\u7b49\u3002\u8a72\u7b49\u9673\u8ff0\u57fa\u65bc\u516c\u53f8\u7576\u524d\u7684\u5224\u65b7\u53ca\u5047\u8a2d\uff0c\u5b58\u5728\u5df2\u77e5\u53ca\u672a\u77e5\u98a8\u96aa\u53ca\u4e0d\u78ba\u5b9a\u6027\uff0c\u5be6\u969b\u7d50\u679c\u53ef\u80fd\u8207\u8a72\u7b49\u524d\u77bb\u6027\u9673\u8ff0\u5b58\u5728\u91cd\u5927\u5dee\u7570\u3002\u9664\u9069\u7528\u6cd5\u5f8b\u6cd5\u898f\u53e6\u6709\u8981\u6c42\u5916\uff0c\u516c\u53f8\u4e0d\u627f\u64d4\u66f4\u65b0\u4efb\u4f55\u524d\u77bb\u6027\u9673\u8ff0\u7684\u8cac\u4efb\u3002<\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4e0a\u6d772026\u5e744\u670820\u65e5 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