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*Stereotactic Body Proton Therapy (SBPT) for Localized Prostate Cancer: Preliminary Clinical Results of Clinician- and Patient-Reported Outcomes. PTCOG-AO-2025.<\/i><\/p>\n

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\u95dc\u65bc\u990a\u548c\u91ab\u7642\u96c6\u5718\uff0c\u8acb\u700f\u89bdwww.hksh.com<\/a>\u3002<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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\u4e9e\u6d32\u9996\u7814\u7a76\u4e94\u6b21\u8cea\u5b50\u6d88\u6ec5\u524d\u5217\u817a\u816b\u7624 \u524d\u5217\u817a\u764c\u7684\u767c\u75c5\u5e74\u9f61\u504f\u5411\u5e74\u9577\uff0c\u4f46\u4e26\u975e\u5e74\u7d00\u8d8a\u5927\u3001\u98a8\u96aa\u8d8a\u9ad8\uff0c\u7576\u4e2d\u4ee565\u81f374\u6b72\u4eba\u58eb\u7684\u767c\u75c5\u7387\u6700\u9ad8\u30022023\u5e74\u7684\u672c\u6e2f\u6578\u64da\u986f\u793a\uff0c\u6b64\u7fa4\u7d44\u7684\u65b0\u75c7\u6578\u76ee\uff0c\u4f54\u6574\u9ad4\u7d04\u4e00\u534a\u3002\u56e0\u6b64\uff0c\u9700\u8981\u66f4\u6709\u6548\u7684\u764c\u75c7\u7ba1\u7406\u65b9\u6848\u3002\u70ba\u63a2\u8a0e\u4e94\u6b21\u8cea\u5b50\u6cbb\u7642\u7684\u81e8\u5e8a\u6210\u6548\uff0c\u990a\u548c\u958b\u5c55\u4e00\u9805\u81e8\u5e8a\u7814\u7a76\uff0c\u5206\u679094\u4f4d\u65e9\u671f\u524d\u5217\u817a\u764c\u60a3\u8005\u65bc2024\u5e746\u6708\u81f32026\u5e741\u6708\u671f\u9593\u9032\u884c\u7acb\u9ad4\u5b9a\u4f4d\u8cea\u5b50\u6cbb\u7642\u524d\u5f8c\u7684\u6578\u64da\u3002\u76ee\u524d\uff0c\u7814\u7a76\u5831\u544a\u7684\u96a8\u8a2a\u4e2d\u4f4d\u6578\u70ba10.93\u500b\u6708\uff08\u7bc4\u570d\uff1a0.9\u81f325.5\u500b\u6708\uff09\u3002\u5728\u4e94\u6b21\u8cea\u5b50\u6cbb\u7642\u5f8c\uff0c\u60a3\u8005\u7684PSA\u6307\u6578\u5f97\u4ee5\u5927\u5e45\u4e0b\u964d\uff0c\u7531\u57fa\u7dda\u768412.57ng\/mL\uff08\u00b113.59ng\/mL\uff09\uff0c\u53ca\u81f3\u5b8c\u6210\u6cbb\u7642\u5f8c\u4e09\u500b\u6708\u7684\u6578\u503c\u70ba1.13ng\/mL\uff08\u00b12.07ng\/mL\uff09\uff0c\u986f\u793a\u5373\u4f7f\u6cbb\u7642\u6b21\u6578\u6e1b\u5c11\uff0c\u4f46\u4ecd\u7dad\u6301\u9ad8\u6210\u6548\u3002 \u9818\u5c0e\u662f\u6b21\u7814\u7a76\u7684\u990a\u548c\u7d9c\u5408\u816b\u7624\u79d1\u4e2d\u5fc3\u526f\u4e3b\u4efb\u3001\u81e8\u5e8a\u816b\u7624\u79d1\u5c08\u79d1\u6f58\u660e\u99ff\u91ab\u751f\u89e3\u91cb\uff0c\u8cea\u5b50\u5c04\u7dda\u9ad8\u5ea6\u96c6\u4e2d\u3001\u5230\u4f4d\u91cb\u653e\uff0c\u53ef\u65bc\u9776\u5340\u5167\u91cd\u64ca\u816b\u7624\uff0c\u56e0\u6b64\u5728\u7814\u7a76\u4e2d\uff0c\u5927\u591a\u6578\u60a3\u8005\u6cbb\u7642\u5f8c\u5747\u6c92\u6709\u51fa\u73fe\u4e8c\u7d1a\u6216\u4ee5\u4e0a\u6bd2\u6027\uff08Grade \u22652 toxicities\uff09\u800c\u5c0e\u81f4\u7684\u4e0d\u826f\u53cd\u61c9\u3002\u5728\u60a3\u8005\u81ea\u8ff0\u7d50\u679c\uff08Patient-Reported Outcome Measures, PROMs\uff09\u4e2d\uff0c\u986f\u793a\u60a3\u8005\u5728\u6cbb\u7642\u5f8c3\u500b\u6708\uff0c\u6ccc\u5c3f\u53ca\u8178\u80c3\u529f\u80fd\u8a55\u5206\u7406\u60f3\uff0c\u53ef\u898b\u6cbb\u7642\u5c0d\u751f\u6d3b\u8cea\u7d20\u5f71\u97ff\u4e0d\u5927\u3002\u7576\u4e2d\u6700\u5e38\u898b\u7684\u4e0d\u826f\u53cd\u61c9\u8207\u6ccc\u5c3f\u7cfb\u7d71\u76f8\u95dc\uff0c\u5728\u6025\u6027\u671f\uff08acute phase\uff09\u4e2d\uff0c\u670933.0%\uff0831\/94\uff09\u60a3\u8005\u51fa\u73fe\u8f03\u8f15\u5fae\u7684\u7b2c\u4e00\u7d1a\u6392\u5c3f\u56f0\u96e3\uff0c\u96a8\u5f8c\u6709\u6240\u6539\u5584\u3002\u662f\u6b21\u7814\u7a76\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u4ee5\u5f97\u51fa\u9577\u671f\u8ddf\u9032\u7684\u6578\u64da\u3002\u4f5c\u70ba\u4e9e\u6d32\u9996\u500b\u4ee5\u78c1\u529b\u5171\u632f\u5c0e\u822a\u9032\u884c5\u6b21\u8cea\u5b50\u6cbb\u7642\u7684\u7814\u7a76\uff0c\u9032\u4e00\u6b65\u78ba\u7acb\u4e86\u990a\u548c\u5728\u5340\u5167\u8cea\u5b50\u6cbb\u7642\u9818\u57df\u7684\u9818\u5c0e\u5730\u4f4d\uff0c\u4e26\u70ba\u65e5\u5f8c\u6574\u500b\u4e9e\u6d32\u5730\u5340\u5236\u5b9a\u66f4\u7cbe\u6e96\u3001\u66f4\u5b89\u5168\u7684\u6cbb\u7642\u65b9\u6848\u63d0\u4f9b\u4e86\u91cd\u8981\u57fa\u790e\u3002 \u5927\u5291\u91cf\u5c11\u6b21\u6578\uff1a\u898f\u5283\u8207\u5b9a\u4f4d \u6f58\u660e\u99ff\u91ab\u751f\u8a73\u7d30\u8b1b\u89e3\u9032\u884c\u300c\u5927\u5291\u91cf\u5c11\u6b21\u6578\u300d\u7684\u6838\u5fc3\u6280\u8853\uff0c\u300c\u6bcf\u500b\u500b\u6848\u3001\u6bcf\u55ae\u6b21\u6cbb\u7642\uff0c\u8cea\u5b50\u5718\u968a\u4e5f\u6703\u4ee5\u7b46\u5c16\u5f0f\u6383\u63cf\u5c04\u675f\u9032\u884c\u5f37\u5ea6\u8abf\u63a7\u8cea\u5b50\u6cbb\u7642\uff08Intensity Modulated Proton Therapy, IMPT\uff09\uff0c\u6cbb\u7642\u524d\u52fe\u5283\u816b\u7624\u5f62\u72c0\u53ca\u5927\u5c0f\uff0c\u518d\u6e96\u78ba\u8a08\u7b97\u6bcf\u675f\u5c04\u675f\u5728\u816b\u7624\u4e0a\u4e0d\u540c\u4f4d\u7f6e\u7684\u7167\u5c04\u5f37\u5ea6\u3002\u60a3\u8005\u5728\u6cbb\u7642\u524d\u4e5f\u9700\u8981\u9032\u884c\u78c1\u529b\u5171\u632f\u53ca\u96fb\u8166\u6383\u63cf\uff0c\u6cbb\u7642\u6642\u8207\u8cea\u5b50\u7cfb\u7d71\u914d\u5099\u7684X\u5149\u5373\u6642\u9020\u5f71\u4f5c\u5c0d\u7167\uff0c\u78ba\u4fdd\u5c0d\u6e96\u9776\u5340\u3002\u300d\u70ba\u6e1b\u4f4e\u5c0d\u524d\u5217\u817a\u9644\u8fd1\u5668\u5b98\u7684\u640d\u5bb3\uff0c\u91ab\u751f\u4ea6\u6703\u6309\u60a3\u8005\u7684\u60c5\u6cc1\uff0c\u65bc\u6cbb\u7642\u524d\u4ee5\u76f4\u8178\u588a\u7247\u6280\u8853\u589e\u52a0\u76f4\u8178\u58c1\u8207\u524d\u5217\u817a\u4e4b\u9593\u7684\u8ddd\u96e2\uff1b\u4e5f\u6703\u9032\u884c\u8180\u80f1\u5bb9\u91cf\u6383\u63cf\uff0c\u8a55\u4f30\u6bcf\u6b21\u6cbb\u7642\u524d\u8180\u80f1\u7684\u5145\u76c8\u7a0b\u5ea6\uff0c\u4ee5\u7784\u6e96\u816b\u7624\u53ca\u6e1b\u5c11\u4e0d\u5fc5\u8981\u7684\u8f3b\u5c04\u91cf\u3002 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*Stereotactic Body Proton Therapy (SBPT) for Localized Prostate Cancer: Preliminary Clinical Results of Clinician- and Patient-Reported Outcomes. PTCOG-AO-2025. \u5982\u6b32\u67e5\u8a62\u6709\u95dc\u990a\u548c\u8cea\u5b50\u6cbb\u7642\u81e8\u5e8a\u7814\u7a76\u7684\u8a73\u60c5\uff0c\u8acb\u96fb\u90f5\u81f3\u00a0RCH-StudyInquiry@hksh-hospital.com. \u95dc\u65bc\u990a\u548c\u91ab\u7642\u96c6\u5718 \u990a\u548c\u91ab\u7642\u96c6\u5718\u65bc\u00a02017 \u5e74\u00a09 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\u4e9e\u6d32\u9996\u7814\u7a76\u4e94\u6b21\u8cea\u5b50\u6d88\u6ec5\u524d\u5217\u817a\u816b\u7624 \u524d\u5217\u817a\u764c\u7684\u767c\u75c5\u5e74\u9f61\u504f\u5411\u5e74\u9577\uff0c\u4f46\u4e26\u975e\u5e74\u7d00\u8d8a\u5927\u3001\u98a8\u96aa\u8d8a\u9ad8\uff0c\u7576\u4e2d\u4ee565\u81f374\u6b72\u4eba\u58eb\u7684\u767c\u75c5\u7387\u6700\u9ad8\u30022023\u5e74\u7684\u672c\u6e2f\u6578\u64da\u986f\u793a\uff0c\u6b64\u7fa4\u7d44\u7684\u65b0\u75c7\u6578\u76ee\uff0c\u4f54\u6574\u9ad4\u7d04\u4e00\u534a\u3002\u56e0\u6b64\uff0c\u9700\u8981\u66f4\u6709\u6548\u7684\u764c\u75c7\u7ba1\u7406\u65b9\u6848\u3002\u70ba\u63a2\u8a0e\u4e94\u6b21\u8cea\u5b50\u6cbb\u7642\u7684\u81e8\u5e8a\u6210\u6548\uff0c\u990a\u548c\u958b\u5c55\u4e00\u9805\u81e8\u5e8a\u7814\u7a76\uff0c\u5206\u679094\u4f4d\u65e9\u671f\u524d\u5217\u817a\u764c\u60a3\u8005\u65bc2024\u5e746\u6708\u81f32026\u5e741\u6708\u671f\u9593\u9032\u884c\u7acb\u9ad4\u5b9a\u4f4d\u8cea\u5b50\u6cbb\u7642\u524d\u5f8c\u7684\u6578\u64da\u3002\u76ee\u524d\uff0c\u7814\u7a76\u5831\u544a\u7684\u96a8\u8a2a\u4e2d\u4f4d\u6578\u70ba10.93\u500b\u6708\uff08\u7bc4\u570d\uff1a0.9\u81f325.5\u500b\u6708\uff09\u3002\u5728\u4e94\u6b21\u8cea\u5b50\u6cbb\u7642\u5f8c\uff0c\u60a3\u8005\u7684PSA\u6307\u6578\u5f97\u4ee5\u5927\u5e45\u4e0b\u964d\uff0c\u7531\u57fa\u7dda\u768412.57ng\/mL\uff08\u00b113.59ng\/mL\uff09\uff0c\u53ca\u81f3\u5b8c\u6210\u6cbb\u7642\u5f8c\u4e09\u500b\u6708\u7684\u6578\u503c\u70ba1.13ng\/mL\uff08\u00b12.07ng\/mL\uff09\uff0c\u986f\u793a\u5373\u4f7f\u6cbb\u7642\u6b21\u6578\u6e1b\u5c11\uff0c\u4f46\u4ecd\u7dad\u6301\u9ad8\u6210\u6548\u3002 \u9818\u5c0e\u662f\u6b21\u7814\u7a76\u7684\u990a\u548c\u7d9c\u5408\u816b\u7624\u79d1\u4e2d\u5fc3\u526f\u4e3b\u4efb\u3001\u81e8\u5e8a\u816b\u7624\u79d1\u5c08\u79d1\u6f58\u660e\u99ff\u91ab\u751f\u89e3\u91cb\uff0c\u8cea\u5b50\u5c04\u7dda\u9ad8\u5ea6\u96c6\u4e2d\u3001\u5230\u4f4d\u91cb\u653e\uff0c\u53ef\u65bc\u9776\u5340\u5167\u91cd\u64ca\u816b\u7624\uff0c\u56e0\u6b64\u5728\u7814\u7a76\u4e2d\uff0c\u5927\u591a\u6578\u60a3\u8005\u6cbb\u7642\u5f8c\u5747\u6c92\u6709\u51fa\u73fe\u4e8c\u7d1a\u6216\u4ee5\u4e0a\u6bd2\u6027\uff08Grade \u22652 toxicities\uff09\u800c\u5c0e\u81f4\u7684\u4e0d\u826f\u53cd\u61c9\u3002\u5728\u60a3\u8005\u81ea\u8ff0\u7d50\u679c\uff08Patient-Reported Outcome Measures, PROMs\uff09\u4e2d\uff0c\u986f\u793a\u60a3\u8005\u5728\u6cbb\u7642\u5f8c3\u500b\u6708\uff0c\u6ccc\u5c3f\u53ca\u8178\u80c3\u529f\u80fd\u8a55\u5206\u7406\u60f3\uff0c\u53ef\u898b\u6cbb\u7642\u5c0d\u751f\u6d3b\u8cea\u7d20\u5f71\u97ff\u4e0d\u5927\u3002\u7576\u4e2d\u6700\u5e38\u898b\u7684\u4e0d\u826f\u53cd\u61c9\u8207\u6ccc\u5c3f\u7cfb\u7d71\u76f8\u95dc\uff0c\u5728\u6025\u6027\u671f\uff08acute phase\uff09\u4e2d\uff0c\u670933.0%\uff0831\/94\uff09\u60a3\u8005\u51fa\u73fe\u8f03\u8f15\u5fae\u7684\u7b2c\u4e00\u7d1a\u6392\u5c3f\u56f0\u96e3\uff0c\u96a8\u5f8c\u6709\u6240\u6539\u5584\u3002\u662f\u6b21\u7814\u7a76\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u4ee5\u5f97\u51fa\u9577\u671f\u8ddf\u9032\u7684\u6578\u64da\u3002\u4f5c\u70ba\u4e9e\u6d32\u9996\u500b\u4ee5\u78c1\u529b\u5171\u632f\u5c0e\u822a\u9032\u884c5\u6b21\u8cea\u5b50\u6cbb\u7642\u7684\u7814\u7a76\uff0c\u9032\u4e00\u6b65\u78ba\u7acb\u4e86\u990a\u548c\u5728\u5340\u5167\u8cea\u5b50\u6cbb\u7642\u9818\u57df\u7684\u9818\u5c0e\u5730\u4f4d\uff0c\u4e26\u70ba\u65e5\u5f8c\u6574\u500b\u4e9e\u6d32\u5730\u5340\u5236\u5b9a\u66f4\u7cbe\u6e96\u3001\u66f4\u5b89\u5168\u7684\u6cbb\u7642\u65b9\u6848\u63d0\u4f9b\u4e86\u91cd\u8981\u57fa\u790e\u3002 \u5927\u5291\u91cf\u5c11\u6b21\u6578\uff1a\u898f\u5283\u8207\u5b9a\u4f4d \u6f58\u660e\u99ff\u91ab\u751f\u8a73\u7d30\u8b1b\u89e3\u9032\u884c\u300c\u5927\u5291\u91cf\u5c11\u6b21\u6578\u300d\u7684\u6838\u5fc3\u6280\u8853\uff0c\u300c\u6bcf\u500b\u500b\u6848\u3001\u6bcf\u55ae\u6b21\u6cbb\u7642\uff0c\u8cea\u5b50\u5718\u968a\u4e5f\u6703\u4ee5\u7b46\u5c16\u5f0f\u6383\u63cf\u5c04\u675f\u9032\u884c\u5f37\u5ea6\u8abf\u63a7\u8cea\u5b50\u6cbb\u7642\uff08Intensity Modulated Proton Therapy, IMPT\uff09\uff0c\u6cbb\u7642\u524d\u52fe\u5283\u816b\u7624\u5f62\u72c0\u53ca\u5927\u5c0f\uff0c\u518d\u6e96\u78ba\u8a08\u7b97\u6bcf\u675f\u5c04\u675f\u5728\u816b\u7624\u4e0a\u4e0d\u540c\u4f4d\u7f6e\u7684\u7167\u5c04\u5f37\u5ea6\u3002\u60a3\u8005\u5728\u6cbb\u7642\u524d\u4e5f\u9700\u8981\u9032\u884c\u78c1\u529b\u5171\u632f\u53ca\u96fb\u8166\u6383\u63cf\uff0c\u6cbb\u7642\u6642\u8207\u8cea\u5b50\u7cfb\u7d71\u914d\u5099\u7684X\u5149\u5373\u6642\u9020\u5f71\u4f5c\u5c0d\u7167\uff0c\u78ba\u4fdd\u5c0d\u6e96\u9776\u5340\u3002\u300d\u70ba\u6e1b\u4f4e\u5c0d\u524d\u5217\u817a\u9644\u8fd1\u5668\u5b98\u7684\u640d\u5bb3\uff0c\u91ab\u751f\u4ea6\u6703\u6309\u60a3\u8005\u7684\u60c5\u6cc1\uff0c\u65bc\u6cbb\u7642\u524d\u4ee5\u76f4\u8178\u588a\u7247\u6280\u8853\u589e\u52a0\u76f4\u8178\u58c1\u8207\u524d\u5217\u817a\u4e4b\u9593\u7684\u8ddd\u96e2\uff1b\u4e5f\u6703\u9032\u884c\u8180\u80f1\u5bb9\u91cf\u6383\u63cf\uff0c\u8a55\u4f30\u6bcf\u6b21\u6cbb\u7642\u524d\u8180\u80f1\u7684\u5145\u76c8\u7a0b\u5ea6\uff0c\u4ee5\u7784\u6e96\u816b\u7624\u53ca\u6e1b\u5c11\u4e0d\u5fc5\u8981\u7684\u8f3b\u5c04\u91cf\u3002 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*Stereotactic Body Proton Therapy (SBPT) for Localized Prostate Cancer: Preliminary Clinical Results of Clinician- and Patient-Reported Outcomes. 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\u9818\u5c0e\u662f\u6b21\u7814\u7a76\u7684\u990a\u548c\u7d9c\u5408\u816b\u7624\u79d1\u4e2d\u5fc3\u526f\u4e3b\u4efb\u3001\u81e8\u5e8a\u816b\u7624\u79d1\u5c08\u79d1\u6f58\u660e\u99ff\u91ab\u751f\u89e3\u91cb\uff0c\u8cea\u5b50\u5c04\u7dda\u9ad8\u5ea6\u96c6\u4e2d\u3001\u5230\u4f4d\u91cb\u653e\uff0c\u53ef\u65bc\u9776\u5340\u5167\u91cd\u64ca\u816b\u7624\uff0c\u56e0\u6b64\u5728\u7814\u7a76\u4e2d\uff0c\u5927\u591a\u6578\u60a3\u8005\u6cbb\u7642\u5f8c\u5747\u6c92\u6709\u51fa\u73fe\u4e8c\u7d1a\u6216\u4ee5\u4e0a\u6bd2\u6027\uff08Grade \u22652 toxicities\uff09\u800c\u5c0e\u81f4\u7684\u4e0d\u826f\u53cd\u61c9\u3002\u5728\u60a3\u8005\u81ea\u8ff0\u7d50\u679c\uff08Patient-Reported Outcome Measures, PROMs\uff09\u4e2d\uff0c\u986f\u793a\u60a3\u8005\u5728\u6cbb\u7642\u5f8c3\u500b\u6708\uff0c\u6ccc\u5c3f\u53ca\u8178\u80c3\u529f\u80fd\u8a55\u5206\u7406\u60f3\uff0c\u53ef\u898b\u6cbb\u7642\u5c0d\u751f\u6d3b\u8cea\u7d20\u5f71\u97ff\u4e0d\u5927\u3002\u7576\u4e2d\u6700\u5e38\u898b\u7684\u4e0d\u826f\u53cd\u61c9\u8207\u6ccc\u5c3f\u7cfb\u7d71\u76f8\u95dc\uff0c\u5728\u6025\u6027\u671f\uff08acute phase\uff09\u4e2d\uff0c\u670933.0%\uff0831\\\/94\uff09\u60a3\u8005\u51fa\u73fe\u8f03\u8f15\u5fae\u7684\u7b2c\u4e00\u7d1a\u6392\u5c3f\u56f0\u96e3\uff0c\u96a8\u5f8c\u6709\u6240\u6539\u5584\u3002\u662f\u6b21\u7814\u7a76\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u4ee5\u5f97\u51fa\u9577\u671f\u8ddf\u9032\u7684\u6578\u64da\u3002\u4f5c\u70ba\u4e9e\u6d32\u9996\u500b\u4ee5\u78c1\u529b\u5171\u632f\u5c0e\u822a\u9032\u884c5\u6b21\u8cea\u5b50\u6cbb\u7642\u7684\u7814\u7a76\uff0c\u9032\u4e00\u6b65\u78ba\u7acb\u4e86\u990a\u548c\u5728\u5340\u5167\u8cea\u5b50\u6cbb\u7642\u9818\u57df\u7684\u9818\u5c0e\u5730\u4f4d\uff0c\u4e26\u70ba\u65e5\u5f8c\u6574\u500b\u4e9e\u6d32\u5730\u5340\u5236\u5b9a\u66f4\u7cbe\u6e96\u3001\u66f4\u5b89\u5168\u7684\u6cbb\u7642\u65b9\u6848\u63d0\u4f9b\u4e86\u91cd\u8981\u57fa\u790e\u3002 \u5927\u5291\u91cf\u5c11\u6b21\u6578\uff1a\u898f\u5283\u8207\u5b9a\u4f4d \u6f58\u660e\u99ff\u91ab\u751f\u8a73\u7d30\u8b1b\u89e3\u9032\u884c\u300c\u5927\u5291\u91cf\u5c11\u6b21\u6578\u300d\u7684\u6838\u5fc3\u6280\u8853\uff0c\u300c\u6bcf\u500b\u500b\u6848\u3001\u6bcf\u55ae\u6b21\u6cbb\u7642\uff0c\u8cea\u5b50\u5718\u968a\u4e5f\u6703\u4ee5\u7b46\u5c16\u5f0f\u6383\u63cf\u5c04\u675f\u9032\u884c\u5f37\u5ea6\u8abf\u63a7\u8cea\u5b50\u6cbb\u7642\uff08Intensity Modulated Proton Therapy, 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*Stereotactic Body Proton Therapy (SBPT) for Localized Prostate Cancer: Preliminary Clinical Results of Clinician- and Patient-Reported Outcomes. 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\u4e9e\u6d32\u9996\u7814\u7a76\u4e94\u6b21\u8cea\u5b50\u6d88\u6ec5\u524d\u5217\u817a\u816b\u7624 \u524d\u5217\u817a\u764c\u7684\u767c\u75c5\u5e74\u9f61\u504f\u5411\u5e74\u9577\uff0c\u4f46\u4e26\u975e\u5e74\u7d00\u8d8a\u5927\u3001\u98a8\u96aa\u8d8a\u9ad8\uff0c\u7576\u4e2d\u4ee565\u81f374\u6b72\u4eba\u58eb\u7684\u767c\u75c5\u7387\u6700\u9ad8\u30022023\u5e74\u7684\u672c\u6e2f\u6578\u64da\u986f\u793a\uff0c\u6b64\u7fa4\u7d44\u7684\u65b0\u75c7\u6578\u76ee\uff0c\u4f54\u6574\u9ad4\u7d04\u4e00\u534a\u3002\u56e0\u6b64\uff0c\u9700\u8981\u66f4\u6709\u6548\u7684\u764c\u75c7\u7ba1\u7406\u65b9\u6848\u3002\u70ba\u63a2\u8a0e\u4e94\u6b21\u8cea\u5b50\u6cbb\u7642\u7684\u81e8\u5e8a\u6210\u6548\uff0c\u990a\u548c\u958b\u5c55\u4e00\u9805\u81e8\u5e8a\u7814\u7a76\uff0c\u5206\u679094\u4f4d\u65e9\u671f\u524d\u5217\u817a\u764c\u60a3\u8005\u65bc2024\u5e746\u6708\u81f32026\u5e741\u6708\u671f\u9593\u9032\u884c\u7acb\u9ad4\u5b9a\u4f4d\u8cea\u5b50\u6cbb\u7642\u524d\u5f8c\u7684\u6578\u64da\u3002\u76ee\u524d\uff0c\u7814\u7a76\u5831\u544a\u7684\u96a8\u8a2a\u4e2d\u4f4d\u6578\u70ba10.93\u500b\u6708\uff08\u7bc4\u570d\uff1a0.9\u81f325.5\u500b\u6708\uff09\u3002\u5728\u4e94\u6b21\u8cea\u5b50\u6cbb\u7642\u5f8c\uff0c\u60a3\u8005\u7684PSA\u6307\u6578\u5f97\u4ee5\u5927\u5e45\u4e0b\u964d\uff0c\u7531\u57fa\u7dda\u768412.57ng\/mL\uff08\u00b113.59ng\/mL\uff09\uff0c\u53ca\u81f3\u5b8c\u6210\u6cbb\u7642\u5f8c\u4e09\u500b\u6708\u7684\u6578\u503c\u70ba1.13ng\/mL\uff08\u00b12.07ng\/mL\uff09\uff0c\u986f\u793a\u5373\u4f7f\u6cbb\u7642\u6b21\u6578\u6e1b\u5c11\uff0c\u4f46\u4ecd\u7dad\u6301\u9ad8\u6210\u6548\u3002 \u9818\u5c0e\u662f\u6b21\u7814\u7a76\u7684\u990a\u548c\u7d9c\u5408\u816b\u7624\u79d1\u4e2d\u5fc3\u526f\u4e3b\u4efb\u3001\u81e8\u5e8a\u816b\u7624\u79d1\u5c08\u79d1\u6f58\u660e\u99ff\u91ab\u751f\u89e3\u91cb\uff0c\u8cea\u5b50\u5c04\u7dda\u9ad8\u5ea6\u96c6\u4e2d\u3001\u5230\u4f4d\u91cb\u653e\uff0c\u53ef\u65bc\u9776\u5340\u5167\u91cd\u64ca\u816b\u7624\uff0c\u56e0\u6b64\u5728\u7814\u7a76\u4e2d\uff0c\u5927\u591a\u6578\u60a3\u8005\u6cbb\u7642\u5f8c\u5747\u6c92\u6709\u51fa\u73fe\u4e8c\u7d1a\u6216\u4ee5\u4e0a\u6bd2\u6027\uff08Grade \u22652 toxicities\uff09\u800c\u5c0e\u81f4\u7684\u4e0d\u826f\u53cd\u61c9\u3002\u5728\u60a3\u8005\u81ea\u8ff0\u7d50\u679c\uff08Patient-Reported Outcome Measures, PROMs\uff09\u4e2d\uff0c\u986f\u793a\u60a3\u8005\u5728\u6cbb\u7642\u5f8c3\u500b\u6708\uff0c\u6ccc\u5c3f\u53ca\u8178\u80c3\u529f\u80fd\u8a55\u5206\u7406\u60f3\uff0c\u53ef\u898b\u6cbb\u7642\u5c0d\u751f\u6d3b\u8cea\u7d20\u5f71\u97ff\u4e0d\u5927\u3002\u7576\u4e2d\u6700\u5e38\u898b\u7684\u4e0d\u826f\u53cd\u61c9\u8207\u6ccc\u5c3f\u7cfb\u7d71\u76f8\u95dc\uff0c\u5728\u6025\u6027\u671f\uff08acute phase\uff09\u4e2d\uff0c\u670933.0%\uff0831\/94\uff09\u60a3\u8005\u51fa\u73fe\u8f03\u8f15\u5fae\u7684\u7b2c\u4e00\u7d1a\u6392\u5c3f\u56f0\u96e3\uff0c\u96a8\u5f8c\u6709\u6240\u6539\u5584\u3002\u662f\u6b21\u7814\u7a76\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u4ee5\u5f97\u51fa\u9577\u671f\u8ddf\u9032\u7684\u6578\u64da\u3002\u4f5c\u70ba\u4e9e\u6d32\u9996\u500b\u4ee5\u78c1\u529b\u5171\u632f\u5c0e\u822a\u9032\u884c5\u6b21\u8cea\u5b50\u6cbb\u7642\u7684\u7814\u7a76\uff0c\u9032\u4e00\u6b65\u78ba\u7acb\u4e86\u990a\u548c\u5728\u5340\u5167\u8cea\u5b50\u6cbb\u7642\u9818\u57df\u7684\u9818\u5c0e\u5730\u4f4d\uff0c\u4e26\u70ba\u65e5\u5f8c\u6574\u500b\u4e9e\u6d32\u5730\u5340\u5236\u5b9a\u66f4\u7cbe\u6e96\u3001\u66f4\u5b89\u5168\u7684\u6cbb\u7642\u65b9\u6848\u63d0\u4f9b\u4e86\u91cd\u8981\u57fa\u790e\u3002 \u5927\u5291\u91cf\u5c11\u6b21\u6578\uff1a\u898f\u5283\u8207\u5b9a\u4f4d \u6f58\u660e\u99ff\u91ab\u751f\u8a73\u7d30\u8b1b\u89e3\u9032\u884c\u300c\u5927\u5291\u91cf\u5c11\u6b21\u6578\u300d\u7684\u6838\u5fc3\u6280\u8853\uff0c\u300c\u6bcf\u500b\u500b\u6848\u3001\u6bcf\u55ae\u6b21\u6cbb\u7642\uff0c\u8cea\u5b50\u5718\u968a\u4e5f\u6703\u4ee5\u7b46\u5c16\u5f0f\u6383\u63cf\u5c04\u675f\u9032\u884c\u5f37\u5ea6\u8abf\u63a7\u8cea\u5b50\u6cbb\u7642\uff08Intensity Modulated Proton Therapy, IMPT\uff09\uff0c\u6cbb\u7642\u524d\u52fe\u5283\u816b\u7624\u5f62\u72c0\u53ca\u5927\u5c0f\uff0c\u518d\u6e96\u78ba\u8a08\u7b97\u6bcf\u675f\u5c04\u675f\u5728\u816b\u7624\u4e0a\u4e0d\u540c\u4f4d\u7f6e\u7684\u7167\u5c04\u5f37\u5ea6\u3002\u60a3\u8005\u5728\u6cbb\u7642\u524d\u4e5f\u9700\u8981\u9032\u884c\u78c1\u529b\u5171\u632f\u53ca\u96fb\u8166\u6383\u63cf\uff0c\u6cbb\u7642\u6642\u8207\u8cea\u5b50\u7cfb\u7d71\u914d\u5099\u7684X\u5149\u5373\u6642\u9020\u5f71\u4f5c\u5c0d\u7167\uff0c\u78ba\u4fdd\u5c0d\u6e96\u9776\u5340\u3002\u300d\u70ba\u6e1b\u4f4e\u5c0d\u524d\u5217\u817a\u9644\u8fd1\u5668\u5b98\u7684\u640d\u5bb3\uff0c\u91ab\u751f\u4ea6\u6703\u6309\u60a3\u8005\u7684\u60c5\u6cc1\uff0c\u65bc\u6cbb\u7642\u524d\u4ee5\u76f4\u8178\u588a\u7247\u6280\u8853\u589e\u52a0\u76f4\u8178\u58c1\u8207\u524d\u5217\u817a\u4e4b\u9593\u7684\u8ddd\u96e2\uff1b\u4e5f\u6703\u9032\u884c\u8180\u80f1\u5bb9\u91cf\u6383\u63cf\uff0c\u8a55\u4f30\u6bcf\u6b21\u6cbb\u7642\u524d\u8180\u80f1\u7684\u5145\u76c8\u7a0b\u5ea6\uff0c\u4ee5\u7784\u6e96\u816b\u7624\u53ca\u6e1b\u5c11\u4e0d\u5fc5\u8981\u7684\u8f3b\u5c04\u91cf\u3002 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*Stereotactic Body Proton Therapy (SBPT) for Localized Prostate Cancer: Preliminary Clinical Results of Clinician- and Patient-Reported Outcomes. 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\u9818\u5c0e\u662f\u6b21\u7814\u7a76\u7684\u990a\u548c\u7d9c\u5408\u816b\u7624\u79d1\u4e2d\u5fc3\u526f\u4e3b\u4efb\u3001\u81e8\u5e8a\u816b\u7624\u79d1\u5c08\u79d1\u6f58\u660e\u99ff\u91ab\u751f\u89e3\u91cb\uff0c\u8cea\u5b50\u5c04\u7dda\u9ad8\u5ea6\u96c6\u4e2d\u3001\u5230\u4f4d\u91cb\u653e\uff0c\u53ef\u65bc\u9776\u5340\u5167\u91cd\u64ca\u816b\u7624\uff0c\u56e0\u6b64\u5728\u7814\u7a76\u4e2d\uff0c\u5927\u591a\u6578\u60a3\u8005\u6cbb\u7642\u5f8c\u5747\u6c92\u6709\u51fa\u73fe\u4e8c\u7d1a\u6216\u4ee5\u4e0a\u6bd2\u6027\uff08Grade \u22652 toxicities\uff09\u800c\u5c0e\u81f4\u7684\u4e0d\u826f\u53cd\u61c9\u3002\u5728\u60a3\u8005\u81ea\u8ff0\u7d50\u679c\uff08Patient-Reported Outcome Measures, 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phase\uff09\u4e2d\uff0c\u670933.0%\uff0831\/94\uff09\u60a3\u8005\u51fa\u73fe\u8f03\u8f15\u5fae\u7684\u7b2c\u4e00\u7d1a\u6392\u5c3f\u56f0\u96e3\uff0c\u96a8\u5f8c\u6709\u6240\u6539\u5584\u3002\u662f\u6b21\u7814\u7a76\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u4ee5\u5f97\u51fa\u9577\u671f\u8ddf\u9032\u7684\u6578\u64da\u3002\u4f5c\u70ba\u4e9e\u6d32\u9996\u500b\u4ee5\u78c1\u529b\u5171\u632f\u5c0e\u822a\u9032\u884c5\u6b21\u8cea\u5b50\u6cbb\u7642\u7684\u7814\u7a76\uff0c\u9032\u4e00\u6b65\u78ba\u7acb\u4e86\u990a\u548c\u5728\u5340\u5167\u8cea\u5b50\u6cbb\u7642\u9818\u57df\u7684\u9818\u5c0e\u5730\u4f4d\uff0c\u4e26\u70ba\u65e5\u5f8c\u6574\u500b\u4e9e\u6d32\u5730\u5340\u5236\u5b9a\u66f4\u7cbe\u6e96\u3001\u66f4\u5b89\u5168\u7684\u6cbb\u7642\u65b9\u6848\u63d0\u4f9b\u4e86\u91cd\u8981\u57fa\u790e\u3002 \u5927\u5291\u91cf\u5c11\u6b21\u6578\uff1a\u898f\u5283\u8207\u5b9a\u4f4d \u6f58\u660e\u99ff\u91ab\u751f\u8a73\u7d30\u8b1b\u89e3\u9032\u884c\u300c\u5927\u5291\u91cf\u5c11\u6b21\u6578\u300d\u7684\u6838\u5fc3\u6280\u8853\uff0c\u300c\u6bcf\u500b\u500b\u6848\u3001\u6bcf\u55ae\u6b21\u6cbb\u7642\uff0c\u8cea\u5b50\u5718\u968a\u4e5f\u6703\u4ee5\u7b46\u5c16\u5f0f\u6383\u63cf\u5c04\u675f\u9032\u884c\u5f37\u5ea6\u8abf\u63a7\u8cea\u5b50\u6cbb\u7642\uff08Intensity Modulated Proton Therapy, 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