{"id":413104,"date":"2026-02-26T22:48:00","date_gmt":"2026-02-26T14:48:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=413104"},"modified":"2026-02-26T22:48:00","modified_gmt":"2026-02-26T14:48:00","slug":"%e5%86%8d%e9%bc%8e%e9%86%ab%e8%97%a5%e5%85%ac%e4%bd%882025%e5%b9%b4%e7%ac%ac%e5%9b%9b%e5%ad%a3%e5%ba%a6%e5%8f%8a%e5%85%a8%e5%b9%b4%e8%b2%a1%e5%8b%99%e6%a5%ad%e7%b8%be%e5%92%8c%e8%bf%91%e6%9c%9f","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=413104","title":{"rendered":"\u518d\u9f0e\u91ab\u85e5\u516c\u4f482025\u5e74\u7b2c\u56db\u5b63\u5ea6\u53ca\u5168\u5e74\u8ca1\u52d9\u696d\u7e3e\u548c\u8fd1\u671f\u516c\u53f8\u9032\u5c55"},"content":{"rendered":"<div>\n<p>\u2013\u00a0 <i>2025<\/i><i>\u5e74\u7b2c\u56db\u5b63\u5ea6\u7e3d\u6536\u5165\u70ba<\/i><i>1.276<\/i><i>\u5104\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u9577<\/i><i>17%<\/i><i>\uff1b<\/i><i>2025<\/i><i>\u5e74\u5168\u5e74\u7e3d\u6536\u5165\u70ba<\/i><i>4.602<\/i><i>\u5104\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u9577<\/i><i>15%<\/i><\/p>\n<p>\u2013\u00a0 <i>Zocilurtatug pelitecan<\/i><i>\uff08<\/i><i>zoci<\/i><i>\uff09\u6709\u671b\u6210\u70ba\u518d\u9f0e\u91ab\u85e5\u9996\u500b\u5728\u5168\u7403\u4e0a\u5e02\u7684\u816b\u7624\u7522\u54c1\uff0c\u9810\u8a08\u5230<\/i><i>2026<\/i><i>\u5e74\u5e95\u5c07\u555f\u52d5\u4e09\u9805\u8a3b\u518a\u6027\u7814\u7a76\uff0c\u6db5\u84cb\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5c0f\u7d30\u80de\u80ba\u764c\u3001\u4e00\u7dda\u5c0f\u7d30\u80de\u80ba\u764c\u53ca\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c<\/i><\/p>\n<p>\u2013\u00a0 <i>\u63a8\u9032\u5177\u6709\u5dee\u7570\u5316\u512a\u52e2\u7684\u5168\u7403\u7ba1\u7dda\uff0c\u5305\u62ec<\/i><i>ZL-1503<\/i><i>\uff08<\/i><i>IL-13<\/i><i>\/<\/i><i>IL-31R\u03b1<\/i><i>\uff09\u3001<\/i><i>ZL-6201<\/i><i>\uff08<\/i><i>LRRC15 ADC<\/i><i>\uff09\u3001<\/i><i>ZL-1222<\/i><i>\uff08<\/i><i>PD-1<\/i><i>\/<\/i><i>IL-12<\/i><i>\uff09\u548c<\/i><i>ZL-1311<\/i><i>\uff08<\/i><i>MUC17<\/i><i>\/<\/i><i>CD3<\/i><i>\u00a0TCE<\/i><i>\uff09<\/i><\/p>\n<p>\u2013\u00a0 <i>\u6301\u7e8c\u63a8\u9032\u95dc\u9375\u5340\u57df\u6027\u9805\u76ee\uff0c<\/i><i>KarXT<\/i><i>\u5728\u4e2d\u570b\u7372\u6279\u4e26\u5df2\u555f\u52d5\u5546\u696d\u5316\u4e0a\u5e02\u7c4c\u5099\u5de5\u4f5c\uff1b<\/i><i>povetacicept<\/i><i>\u7528\u65bc<\/i><i>IgA<\/i><i>\u814e\u75c5\u3001<\/i><i>elegrobart<\/i><i>\u7528\u65bc\u7532\u72c0\u817a\u773c\u75c5\u7684\u95dc\u9375\u6578\u64da\u9810\u8a08\u5c07\u65bc<\/i><i>2026<\/i><i>\u5e74\u516c\u4f48<\/i><\/p>\n<p class=\"prntac\">\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u5c07\u65bc2026\u5e742\u670826\u65e5\u4e0a\u53488:00\uff08\u7f8e\u570b\u6771\u90e8\u6642\u9593\uff09\/\u665a\u4e0a9:00\uff08\u9999\u6e2f\u6642\u9593\uff09\u8209\u884c<\/p>\n<p><span class=\"legendSpanClass\">\u4e2d\u570b\u4e0a\u6d77\u548c\u7f8e\u570b\u99ac\u85a9\u8af8\u585e\u5dde\u528d\u6a4b\u5e02<\/span><span class=\"legendSpanClass\">2026\u5e742\u670826\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u518d\u9f0e\u91ab\u85e5\u6709\u9650\u516c\u53f8\uff08\u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aZLAB\uff1b\u9999\u6e2f\u806f\u4ea4\u6240\u80a1\u4efd\u4ee3\u865f\uff1a9688\uff09\u4eca\u65e5\u516c\u4f48\u4e86 2025 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Smiley\u8868\u793a\uff1a\u300cKarXT\u662f\u518d\u9f0e\u91cd\u8981\u7684\u65b0\u589e\u9577\u5f15\u64ce\uff0c\u8fd1\u671f\u5176\u88ab\u7d0d\u5165\u4e86\u570b\u5bb6\u7cbe\u795e\u5206\u88c2\u75c7\u5c08\u5bb6\u5171\u8b58\uff0c\u51f8\u986f\u4e86\u5176\u5275\u65b0\u6a5f\u5236\u53ca\u70ba\u7cbe\u795e\u5206\u88c2\u75c7\u60a3\u8005\u5e36\u4f86\u6709\u610f\u7fa9\u5f71\u97ff\u7684\u6f5b\u529b\uff0c\u6b63\u4e0d\u65b7\u7372\u5f97\u66f4\u52a0\u5ee3\u6cdb\u7684\u8a8d\u53ef\u3002\u6211\u5011\u6b63\u5728\u901a\u904e\u64f4\u5927\u91ab\u9662\u8986\u84cb\u548c\u652f\u6301\u66f4\u9577\u7684\u6cbb\u7642\u9031\u671f\uff0c\u9032\u4e00\u6b65\u978f\u56fa\u827e\u52a0\u83ab\u5fb7\u7684\u5e02\u5834\u5730\u4f4d\u3002\u540c\u6642\uff0c\u6211\u5011\u6b63\u7a4d\u6975\u6e96\u5099TIVDAK\u7684\u7372\u6279\u4e0a\u5e02\u2014\u2014\u9019\u5c07\u9032\u4e00\u6b65\u5f37\u5316\u6211\u5011\u5728\u5a66\u7624\u9818\u57df\u7684\u7ba1\u7dda\u4f48\u5c40\uff0c\u4ee5\u53ca\u816b\u7624\u96fb\u5834\u6cbb\u7642\u7528\u65bc\u80f0\u817a\u764c\u7684\u6f5b\u5728\u7372\u6279\u3002\u5c55\u671b2026\u5e74\u53ca\u672a\u4f86\uff0c\u65b0\u7522\u54c1\u4e0a\u5e02\u3001\u6f5b\u5728\u9069\u61c9\u8b49\u62d3\u5c55\u4ee5\u53ca\u5168\u7403\u9805\u76ee\u7684\u63a8\u9032\uff0c\u5c07\u52a9\u529b\u6211\u5011\u5be6\u73fe\u672a\u4f86\u591a\u5e74\u7684\u589e\u9577\u548c\u8ca1\u52d9\u72c0\u6cc1\u7684\u6301\u7e8c\u6539\u5584\u3002\u300d<\/p>\n<p><b><u>2025<\/u><\/b><b><u>\u5e74\u7b2c\u56db\u5b63\u5ea6\u548c\u5168\u5e74\u8ca1\u52d9\u696d\u7e3e<\/u><\/b><\/p>\n<ul type=\"disc\">\n<li>2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u7e3d\u6536\u5165\u70ba 1.276 \u5104\u7f8e\u5143\uff0c2025 \u5e74\u5168\u5e74\u7e3d\u6536\u5165\u70ba 4.602 \u5104\u7f8e\u5143\u3002\u7b2c\u56db\u5b63\u5ea6\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba1.271\u5104\u7f8e\u5143\uff0c2024 \u5e74\u540c\u671f\u70ba 1.085 \u5104\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957717%\uff0c\u6309\u56fa\u5b9a\u532f\u7387(CER)\u8a08\u7b97\u589e\u9577 16%\uff1b2025\u5e74\u5168\u5e74\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba4.572\u5104\u7f8e\u5143\uff0c2024\u5e74\u540c\u671f\u70ba 3.976 \u5104\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u9577 15%\uff0c\u6309 CER \u8a08\u7b97\u540c\u6bd4\u589e\u957716%\u3002\u7522\u54c1\u6536\u5165\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u9f0e\u512a\u6a02\u548c\u7d10\u518d\u6a02\u7684\u92b7\u91cf\u589e\u9577\u3002\n<ul type=\"disc\">\n<li>\u5247\u6a02 2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba 5,600 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\u5104\u7f8e\u5143\uff0c\u53bb\u5e74\u540c\u671f\u70ba1.871\u5104\u7f8e\u5143\u3002\u5118\u7ba1PARP\u6291\u5236\u5291\u985e\u7522\u54c1\u7af6\u722d\u614b\u52e2\u8b8a\u5316\uff0c\u5247\u6a02\u7e7c\u7e8c\u4fdd\u6301\u4e2d\u570b\u5167\u5730\u5375\u5de2\u764c\u9818\u57dfPARP\u6291\u5236\u5291\u9662\u5167\u92b7\u552e\u9818\u8ecd\u8005\u5730\u4f4d\u3002<\/li>\n<li>2025\u5e74\u7b2c\u56db\u5b63\u5ea6\uff0c\u885b\u5049\u8fe6\u548c\u885b\u529b\u8fe6\u7684\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba2,190\u842c\u7f8e\u5143\uff0c\u5176\u4e2d\u5305\u62ec\u8207\u885b\u5049\u8fe6\u7e8c\u7d04\u570b\u5bb6\u91ab\u4fdd\u85e5\u54c1\u76ee\u9304\uff08NRDL\uff09\u76f8\u95dc\u7684560\u842c\u7f8e\u5143\u7684\u92b7\u552e\u8fd4\u5229\uff1b2024\u5e74\u540c\u671f\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba3,000\u842c\u7f8e\u5143\u30022025\u5e74\u5168\u5e74\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba9,420\u842c\u7f8e\u5143\uff0c2024\u5e74\u540c\u671f\u70ba9,360\u842c\u7f8e\u5143\u3002<\/li>\n<li>\u9f0e\u512a\u6a02\u65bc2024\u5e74\u7b2c\u56db\u5b63\u5ea6\u4e0a\u5e02\uff0c2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba1,070\u842c\u7f8e\u5143\uff0c\u8f03\u53bb\u5e74\u540c\u671f\u7684330\u842c\u7f8e\u5143\u589e\u9577225%\u30022025\u5e74\u5168\u5e74\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba2,290\u842c\u7f8e\u5143\uff0c\u8f03\u53bb\u5e74\u540c\u671f\u7684330\u842c\u7f8e\u5143\u589e\u9577593%\u3002\u9019\u4e00\u589e\u9577\u4e3b\u8981\u5f97\u76ca\u65bc\u5f37\u52c1\u7684\u60a3\u8005\u9700\u6c42\u548c\u91ab\u9662\u8986\u84cb\u7bc4\u570d\u7684\u6301\u7e8c\u64f4\u5927\uff0c\u4f46\u53d7\u5230\u672c\u5e74\u5167\u4f9b\u61c9\u9650\u5236\u7684\u90e8\u5206\u5f71\u97ff\u3002<\/li>\n<li>\u7d10\u518d\u6a022025\u5e74\u7b2c\u56db\u5b63\u5ea6\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba1,600\u842c\u7f8e\u5143\uff0c\u8f03\u53bb\u5e74\u540c\u671f\u76841,100\u842c\u7f8e\u5143\u589e\u957745%\u30022025\u5e74\u5168\u5e74\u7684\u7522\u54c1\u6536\u5165\u6de8\u984d\u70ba6,080\u842c\u7f8e\u5143\uff0c\u8f03\u53bb\u5e74\u540c\u671f\u76844,320\u842c\u7f8e\u5143\u589e\u957741%\u3002\u9019\u4e00\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u5e02\u5834\u8986\u84cb\u7387\u548c\u6ef2\u900f\u7387\u7684\u63d0\u5347\u3002<\/li>\n<\/ul>\n<\/li>\n<li>2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u7684\u7814\u767c\u958b\u652f\u70ba6,160\u842c\u7f8e\u5143\uff0c2024\u5e74\u540c\u671f\u70ba5,230\u842c\u7f8e\u5143\u30022025\u5e74\u5168\u5e74\u7814\u767c\u958b\u652f\u70ba2.209\u5104\u7f8e\u5143\uff0c2024\u5e74\u540c\u671f\u70ba2.345\u5104\u7f8e\u5143\u3002\u7b2c\u56db\u5b63\u5ea6\u7814\u767c\u958b\u652f\u7684\u589e\u52a0\u4e3b\u8981\u6e90\u65bc\u81e8\u5e8a\u7814\u7a76\u7684\u63a8\u9032\u3002\u5168\u5e74\u7814\u767c\u958b\u652f\u4e0b\u964d\u4e3b\u8981\u5f97\u76ca\u65bc\u6230\u7565\u8cc7\u6e90\u512a\u5316\u8abf\u6574\u5e36\u4f86\u7684\u4eba\u54e1\u6210\u672c\u4e0b\u964d\u3002<\/li>\n<li>2025 \u5e74\u7b2c\u56db\u5b63\u5ea6\u7684\u92b7\u552e\u3001\u4e00\u822c\u53ca\u884c\u653f (SG&amp;A) \u958b\u652f\u70ba 7,300 \u842c\u7f8e\u5143\uff0c2024 \u5e74\u540c\u671f\u70ba8,260 \u842c\u7f8e\u5143\u30022025\u5e74\u5168\u5e74\u7684SG&amp;A\u958b\u652f\u70ba 2.776 \u5104\u7f8e\u5143\uff0c 2024 \u5e74\u540c\u671f\u70ba 2.987 \u5104\u7f8e\u5143\u3002\u9019\u4e00\u4e0b\u964d\u4e3b\u8981\u7531\u65bc\u6230\u7565\u8cc7\u6e90\u512a\u5316\u8abf\u6574\u6240\u5e36\u4f86\u4e00\u822c\u53ca\u884c\u653f\u958b\u652f\u7684\u4e0b\u964d\u3002<\/li>\n<li>2025 \u5e74\u7b2c\u56db\u5b63\u5ea6\u548c 2025 \u5e74\u5168\u5e74\u7684\u7d93\u71df\u8667\u640d\u5206\u5225\u70ba 6,940 \u842c\u7f8e\u5143\u548c 2.294 \u5104\u7f8e\u5143\uff0c\u7d93\u8abf\u6574\u6263\u9664\u6298\u820a\u3001\u6524\u92b7\u548c\u4ee5\u80a1\u4efd\u70ba\u57fa\u790e\u7684\u916c\u91d1\u7b49\u975e\u73fe\u91d1\u652f\u51fa\u5f8c\u5206\u5225\u70ba4,960\u842c\u7f8e\u5143\u548c1.488\u5104\u7f8e\u5143\uff0c2024 \u5e74\u7b2c\u56db\u5b63\u5ea6\u548c 2024 \u5e74\u5168\u5e74\u7684\u7d93\u71df\u8667\u640d\u5206\u5225\u70ba6,790\u842c\u7f8e\u5143\u548c2.821\u5104\u7f8e\u5143\u3002\u672c\u65b0\u805e\u7a3f\u672b\u5c3e\u9644\u6709\u7d93\u71df\u8667\u640d\uff08\u7f8e\u570b\u516c\u8a8d\u6703\u8a08\u6e96\u5247\uff09\u548c\u8abf\u6574\u5f8c\u7684\u7d93\u71df\u8667\u640d\uff08\u975e\u7f8e\u570b\u516c\u8a8d\u6703\u8a08\u6e96\u5247\uff09\u7684\u5c0d\u6bd4\u3002<\/li>\n<li>2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u8667\u640d\u6de8\u984d\u70ba 5,040 \u842c\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.05\u7f8e\u5143\uff08\u6bcf\u4efd\u7f8e\u570b\u5b58\u6258\u80a1\u4efd\uff08ADS\uff09\u8667\u640d\u70ba0.46\u7f8e\u5143\uff09\uff0c2024 \u5e74\u540c\u671f\u8667\u640d\u6de8\u984d\u70ba 8,170 \u842c\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.08\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba0.80 \u7f8e\u5143\uff09\u30022025 \u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 1.755 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.16\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba1.60\u7f8e\u5143\uff09\uff0c2024 \u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 2.571 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.26\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba2.60\u7f8e\u5143\uff09\u3002\u8667\u640d\u6de8\u984d\u6e1b\u5c11\u4e3b\u8981\u662f\u7531\u65bc\u7522\u54c1\u6536\u5165\u589e\u9577\u5feb\u65bc\u904b\u71df\u958b\u652f\u4ee5\u53ca\u532f\u514c\u640d\u5931\u8f49\u70ba\u532f\u514c\u6536\u76ca\uff0c\u4f46\u88ab\u5229\u606f\u6536\u76ca\u6e1b\u5c11\u6240\u62b5\u92b7\u3002<\/li>\n<li>\u622a\u81f3 2025 \u5e74 12 \u6708 31 \u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u548c\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba 7.896 \u5104\u7f8e\u5143\uff0c\u622a\u81f3 2024 \u5e74 12 \u6708 31 \u65e5\u70ba 8.797\u5104\u7f8e\u5143\u3002<\/li>\n<\/ul>\n<p><b><u>2026<\/u><\/b><b><u>\u5e74\u6230\u7565\u91cd\u9ede<\/u><\/b><\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\u57282026\u5e74\u5c07\u805a\u7126\u4ee5\u4e0b\u6230\u7565\u91cd\u9ede\uff0c\u4ee5\u9a45\u52d5\u8fd1\u671f\u696d\u7e3e\u8207\u9577\u671f\u5168\u7403\u50f9\u503c\u7684\u63d0\u5347\uff1a<\/p>\n<p><b><i>\u63a8\u9032\u816b\u7624\u548c\u514d\u75ab\u9818\u57df\u5dee\u7570\u5316\u7684\u5168\u7403\u9805\u76ee<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>Zocilurtatug pelitecan<\/b> (zoci) (\u9776\u5411DLL3 ADC): \u81f32026\u5e74\u5e95\uff0c\u63a8\u9032\u57282L+ SCLC\u30011L SCLC\u53ca\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c(NECs)\u9818\u57df\u7684\u4e09\u9805\u8a3b\u518a\u6027\u95dc\u9375\u7814\u7a76\u30022026\u5e74\u5167\u9810\u8a08\u5c07\u6709\u4e09\u9805\u6578\u64da\u8b80\u51fa\uff0c\u5305\u62ec\uff1a\n<ul type=\"disc\">\n<li><b>2L+ SCLC<\/b>: \u66f4\u65b0\u7684\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\uff0c\u4ee5\u5c55\u793a\u5728\u4f34\u6709\u8166\u8f49\u79fb\u7684\u60a3\u8005\u4e2d\u7684\u9871\u5167\u7de9\u89e3\u6548\u679c<\/li>\n<li><b>1L SCLC<\/b>: \u6b63\u5728\u9032\u884c\u76841\u671f\u7814\u7a76\u6578\u64da\uff0c\u8a55\u4f30\u8207PD-L1\u6291\u5236\u5291\u00b1\u5316\u7642\u806f\u5408\u7684\u96d9\u806f\u53ca\u4e09\u806f\u65b9\u6848\uff1b\u555f\u52d5\u8207\u65b0\u578b\u7642\u6cd5\u65b9\u6848\u806f\u7528\u7684\u5168\u74031\u671f\u7814\u7a76<\/li>\n<li><b>\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c<\/b>\uff1a\u4f86\u81ea\u6b63\u5728\u9032\u884c\u7684\u5168\u74031b\/2\u671f\u7814\u7a76\u4e2d1b\u671f\u90e8\u5206\u7684\u6578\u64da<\/li>\n<\/ul>\n<\/li>\n<li><b>ZL-1503<\/b> (IL-13\/IL-31 R\u03b1\u96d9\u7279\u7570\u6027\u6297\u9ad4)\uff1a\u9810\u8a08\u57282026\u5e74\u4e0b\u534a\u5e74\u516c\u4f48\u6b63\u5728\u9032\u884c\u7684\u5168\u74031\/1b\u671f\u7814\u7a76\u7684\u9996\u6b21\u4eba\u9ad4(FIH)\u6578\u64da\uff0c\u70ba\u7528\u65bc\u7279\u61c9\u6027\u76ae\u708e(AD)\u76842\u671f\u81e8\u5e8a\u958b\u767c\u5960\u5b9a\u57fa\u790e\u3002<\/li>\n<li><b>ZL-6201<\/b> (\u9776\u5411LRRC15 ADC) \uff1a\u5168\u74031\u671f\u7814\u7a76\u6b63\u5728\u9032\u884c\u4e2d\u3002<\/li>\n<li><b>ZL-1222<\/b> (PD-1\/IL-12\u514d\u75ab\u7d30\u80de\u56e0\u5b50)\uff1a\u65b0\u85e5\u81e8\u5e8a\u8a66\u9a57\u7533\u8acb(IND)\u652f\u6301\u6027\u7814\u7a76\u9810\u8a08\u65bc2026\u5e74\u5b8c\u6210\u3002<\/li>\n<li><b>ZL-1311<\/b>\u00a0(\u9776\u5411MUC17\u7684T\u7d30\u80de\u929c\u63a5\u5668(TCE))\uff1a\u9810\u8a08\u5e74\u5e95\u524d\u63d0\u4ea4IND\u3002<\/li>\n<li>\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u69cb\u5efa\u5728TCE\u9818\u57df\u7684\u80fd\u529b\uff0c\u4e26\u6301\u7e8c\u63a2\u7d22IL-12\u4ee5\u5916\u7684\u5176\u4ed6\u514d\u75ab\u7d30\u80de\u56e0\u5b50\uff0c\u5c07\u5728\u5e74\u5167\u63d0\u4f9b\u66f4\u591a\u7d30\u7bc0\u3002<\/li>\n<\/ul>\n<p><b><i>\u5546\u696d\u5316\u57f7\u884c\u8207\u8fd1\u671f\u95dc\u9375\u7684\u5340\u57df\u4e0a\u5e02\u7522\u54c1\u9a45\u52d5\u7a69\u5065\u589e\u9577<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u885b\u5049\u8fe6\u548c\u885b\u529b\u8fe6<\/b>: \u7e7c\u7e8c\u63d0\u9ad8\u5728\u5168\u8eab\u578b\u91cd\u75c7\u808c\u7121\u529b(gMG)\u548c\u6162\u6027\u708e\u6027\u812b\u9ad3\u9798\u6027\u591a\u767c\u6027\u795e\u7d93\u6839\u795e\u7d93\u75c5(CIDP)\u9818\u57df\u7684\u60a3\u8005\u4f7f\u7528\u548c\u6cbb\u7642\u6301\u7e8c\u6642\u9593\u3002<\/li>\n<li><b>KarXT<\/b>\uff1a\u8a08\u5283\u65bc2026\u5e74\u4e0a\u534a\u5e74\u5546\u696d\u5316\u4e0a\u5e02\uff0c\u7a4d\u6975\u958b\u5c55\u91dd\u5c0d\u6027\u5546\u696d\u5316\u7b56\u7565\u3001\u91ab\u751f\u6559\u80b2\u3001\u771f\u5be6\u4e16\u754c\u8b49\u64da\u751f\u6210\uff0c\u4e26\u70ba\u53ef\u80fd\u65bc2027\u5e74\u7d0d\u5165NRDL\u505a\u597d\u6e96\u5099\u3002<\/li>\n<li><b>Povetacicept<\/b>\u548c<b>elegrobart<\/b>\u00a0\uff1a\u5747\u9810\u8a08\u57282026\u5e74\u7372\u5f97\u95dc\u9375\u6027\u6578\u64da\u8b80\u51fa\uff0c\u6709\u671b\u65bc\u8fd1\u671f\u9032\u4e00\u6b65\u9a45\u52d5\u5340\u57df\u6027\u6536\u5165\u7684\u589e\u9577\u3002<\/li>\n<\/ul>\n<p><b><u>\u91cd\u8981\u516c\u53f8\u9032\u5c55<\/u><\/b><\/p>\n<p>\u81ea\u4e0a\u6b21\u8ca1\u5831\u767c\u4f48\u4ee5\u4f86\u518d\u9f0e\u91ab\u85e5\u7684\u95dc\u9375\u516c\u53f8\u9032\u5c55\u5305\u62ec\uff1a<\/p>\n<ul type=\"disc\">\n<li><b>\u696d\u52d9\u62d3\u5c55\uff1a<\/b>\n<ul type=\"disc\">\n<li>\u6211\u5011\u7372\u5f97\u4e86ZL-1311\uff08\u4e00\u6b3e\u9776\u5411MUC17\u7684\u65b0\u4e00\u4ee3T\u7d30\u80de\u929c\u63a5\u5668\uff09\u7684\u5168\u7403\u7368\u5bb6\u958b\u767c\u548c\u5546\u696d\u5316\u6b0a\u76ca\u3002MUC17\u662f\u4e00\u500b\u524d\u666f\u5ee3\u95ca\u4e14\u53ef\u6210\u85e5\u7684\u816b\u7624\u76f8\u95dc\u6297\u539f\uff0c\u5728\u9ad8\u9054\u7d0450%\u7684\u80c3\u764c\u548c\u80c3\u98df\u7ba1\u7d50\u5408\u90e8\u764c\u4e2d\u5b58\u5728\u904e\u8868\u9054\u3002\u9019\u4e00\u9805\u76ee\u6a19\u8a8c\u8457\u518d\u9f0e\u91ab\u85e5\u7372\u5f97\u4e86\u9996\u500b\u5177\u6709\u5168\u7403\u6b0a\u76ca\u7684TCE\uff0c\u901a\u904e\u5229\u7528\u904e\u5f80\u5728\u6d88\u5316\u9053\u764c\u75c7\u9818\u57df\u5c08\u696d\u4f48\u5c40\uff0c\u6230\u7565\u6027\u64f4\u5c55\u4e86\u6211\u5011\u7684\u816b\u7624\u514d\u75ab\u7522\u54c1\u7d44\u5408\u3002ZL-1311\u9810\u8a08\u5c07\u5728\u4eca\u5e74\u9032\u5165\u5168\u7403\u81e8\u5e8a\u958b\u767c\u3002<\/li>\n<li>\u6211\u5011\u4ea6\u8207\u8cfd\u751f\u85e5\u696d\u5c31\u5967\u51f1\u6a02<sup>\u00ae<\/sup>\uff08\u745e\u666e\u66ff\u5c3c\uff09\u9054\u6210\u4e86\u6230\u7565\u5408\u4f5c\u3002\u9019\u6b3e\u7522\u54c1\u65bc2024\u5e745\u6708\u5728\u4e2d\u570b\u5167\u5730\u7372\u6279\u7528\u65bcROS1\u967d\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff0c\u4e26\u65bc2026\u5e741\u6708\u7372\u6279\u7528\u65bcNTRK\u967d\u6027\u5be6\u9ad4\u7624\u3002\u518d\u9f0e\u91ab\u85e5\u5c07\u901a\u904e\u6b64\u9805\u5408\u4f5c\uff0c\u501f\u52a9\u8cfd\u751f\u85e5\u696d\u7684\u5546\u696d\u5316\u4f48\u5c40\uff0c\u52a0\u901f\u9019\u4e00\u5275\u65b0\u7642\u6cd5\u7684\u5546\u696d\u5316\u9032\u7a0b\uff0c\u4ee5\u76e1\u5feb\u60e0\u53ca\u4e2d\u570b\u5167\u5730\u7684\u4e9f\u9700\u60a3\u8005\u3002<\/li>\n<\/ul>\n<\/li>\n<li>NRDL\u66f4\u65b0\uff1a2025\u5e7412\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5ba3\u4f48\u885b\u5049\u8fe6\uff08\u827e\u52a0\u83ab\u5fb7\u03b1\u6ce8\u5c04\u6db2\uff09\u7528\u65bc\u6297\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6297\u9ad4\u967d\u6027\u7684\u5168\u8eab\u578b\u91cd\u75c7\u808c\u7121\u529b\u3001\u7d10\u518d\u6a02\uff08\u5967\u99ac\u74b0\u7d20\uff09\u7528\u65bc\u793e\u5340\u7372\u5f97\u6027\u7d30\u83cc\u6027\u80ba\u708e\u548c\u6025\u6027\u7d30\u83cc\u6027\u76ae\u819a\u53ca\u76ae\u819a\u7d50\u69cb\u611f\u67d3\u3001\u5247\u6a02\uff08\u5c3c\u62c9\u5e15\u5229\uff09\u7528\u65bc\u6210\u4eba\u9251\u654f\u611f\u5fa9\u767c\u5375\u5de2\u764c\u548c\u4e00\u7dda\u5375\u5de2\u764c\u7dad\u6301\u6cbb\u7642\u6210\u529f\u7e8c\u7d04NRDL\u3002<\/li>\n<\/ul>\n<p><b><u>\u8fd1\u671f\u7ba1\u7dda\u4eae\u9ede<\/u><\/b><\/p>\n<p>\u81ea\u4e0a\u6b21\u8ca1\u5831\u767c\u4f48\u4ee5\u4f86\u518d\u9f0e\u91ab\u85e5\u7684\u95dc\u9375\u5019\u9078\u7522\u54c1\u9032\u5c55\u5305\u62ec\uff1a<\/p>\n<p><b><i>\u816b\u7624\u9818\u57df\u7ba1\u7dda<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>Zocilurtatug Pelitecan (zoci, DLL3 ADC):<\/b>\u00a0\n<ul type=\"disc\">\n<li><i>\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5ee3\u6cdb\u671f\u5c0f\u7d30\u80de\u80ba\u764c<\/i>\uff1a\u8a55\u4f30zoci\u5c0d\u6bd4\u7814\u7a76\u8005\u9078\u64c7\u7684\u6cbb\u7642\u65b9\u6848\uff08\u6258\u6cca\u66ff\u5eb7\u3001\u8606\u6bd4\u66ff\u5b9a\u6216\u6c28\u67d4\u6bd4\u661f\uff09\u5728\u5fa9\u767c\u6027\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\u4e2d\u7684\u7642\u6548\u548c\u5b89\u5168\u6027\u7684\u5168\u7403\u00a03\u671f\u7814\u7a76\u6b63\u5728\u9032\u884c\u4e2d\u3002\u9019\u9805\u95dc\u9375\u6027\u7814\u7a76\u8a08\u5283\u5165\u7d44\u7d04480\u540d\u4e8c\u7ddaSCLC\u6216tarlatamab\u7d93\u6cbb\u7684\u4e09\u7dda\u00a0SCLC\u60a3\u8005\uff0c\u5927\u90e8\u5206\u5165\u7d44\u9810\u8a08\u5728\u4eca\u5e74\u5b8c\u6210\u3002<\/li>\n<li><i>\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c<\/i>\uff1a2026\u5e741\u6708\uff0c\u6b63\u5728\u9032\u884c\u7684\u7528\u65bc\u795e\u7d93\u5167\u5206\u6ccc\u764c\u7684\u5168\u74031b\/2\u671f\u7814\u7a76\u76842\u671f\u90e8\u5206\u5b8c\u6210\u4e86\u9996\u4f8b\u60a3\u8005\u7d66\u85e5\u3002\u518d\u9f0e\u91ab\u85e5\u8a08\u5283\u57282026\u5e74\u4e0a\u534a\u5e74\u516c\u4f481b\u671f\u90e8\u5206\u7684\u521d\u6b65\u6578\u64da\uff0c\u5728\u5e74\u5167\u5b8c\u62102\u671f\u90e8\u5206\u7684\u60a3\u8005\u5165\u7d44\uff0c\u4e26\u63a8\u9032\u9019\u4e00\u7814\u7a76\u9032\u5165\u8a3b\u518a\u6027\u968e\u6bb5\u3002<\/li>\n<\/ul>\n<\/li>\n<li><b>ZL-6201 (LRRC15 ADC)<\/b>\uff1a2026\u5e741\u6708\uff0cFDA\u6279\u51c6ZL-6201\u7528\u65bc\u6cbb\u7642\u8089\u7624\u53ca\u5176\u4ed6\u6f5b\u5728LRRC15\u967d\u6027\u5be6\u9ad4\u7624\u60a3\u8005\u7684\u5168\u7403<b>1<\/b>\u671f\u7814\u7a76\u7684\u65b0\u85e5\u81e8\u5e8a\u8a66\u9a57\u7533\u8acb\u3002\u9019\u4e00\u5168\u7403<b>1<\/b>\u671f\u81e8\u5e8a\u7814\u7a76\u5df2\u7d93\u555f\u52d5\u3002<\/li>\n<li><b>\u816b\u7624\u96fb\u5834\u6cbb\u7642\uff08<\/b><b>TTFields<\/b><b>\uff09<\/b>\uff1a2026\u5e742\u6708\uff0cFDA\u6279\u51c6Optune Pax<sup>\u00ae<\/sup>\u806f\u5408\u5409\u897f\u4ed6\u6ff1\u548c\u767d\u86cb\u767d\u7d50\u5408\u578b\u7d2b\u6749\u9187\u7528\u65bc\u6cbb\u7642\u5c40\u90e8\u665a\u671f\u80f0\u817a\u764c\u6210\u4eba\u60a3\u8005\u3002\u9019\u662f\u8fd130\u5e74\u4f86\u9996\u500b\u7372FDA\u6279\u51c6\u7528\u65bc\u5c40\u90e8\u665a\u671f\u80f0\u817a\u764c\u6cbb\u7642\u7684\u65b9\u6848\u30022025\u5e748\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u6388\u4e88\u5176\u7528\u65bc\u6cbb\u7642\u80f0\u817a\u764c\u7684\u5275\u65b0\u91ab\u7642\u5668\u68b0\u8a8d\u5b9a\u3002<\/li>\n<li><b>\u5967\u51f1\u6a02<\/b><sup>\u00ae<\/sup><b>\u00a0(<\/b><b>\u745e\u666e\u66ff\u5c3c<\/b><b>, ROS1\/TRK): <\/b>2025\u5e7412\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u5967\u51f1\u6a02<sup>\u00ae<\/sup>\u7528\u65bc\u6cbb\u7642\u651c\u5e36\u795e\u7d93\u71df\u990a\u916a\u6c28\u9178\u53d7\u9ad4\u6fc0\u9176\uff08NTRK\uff09\u57fa\u56e0\u878d\u5408\u7684\u5be6\u9ad4\u7624\u6210\u4eba\u60a3\u8005\u7684\u88dc\u5145\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff08sNDA\uff09\u3002<\/li>\n<\/ul>\n<p><b><i>\u514d\u75ab\u3001\u795e\u7d93\u79d1\u5b78\u53ca\u611f\u67d3\u6027\u75be\u75c5\u9818\u57df\u7ba1\u7dda<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>ZL-1503<\/b><b>\uff08<\/b><b>IL-13\/IL-31 R<\/b><b>\u03b1<\/b><b>\uff09<\/b>\uff1a2025\u5e7412\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5728\u4e00\u9805\u8a55\u4f30ZL-1503\u7528\u65bc\u6cbb\u7642\u7279\u61c9\u6027\u76ae\u708e\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u85e5\u4ee3\u52d5\u529b\u5b78\u53ca\u6709\u6548\u6027\u7684\u5168\u74031\/1b\u671f\u7814\u7a76\u4e2d\u5b8c\u6210\u4e86\u9996\u4f8b\u53d7\u8a66\u8005\u7d66\u85e5\u3002\u518d\u9f0e\u91ab\u85e5\u9810\u8a08\u5c07\u57282026\u5e74\u4e0b\u534a\u5e74\u5831\u544a\u4f86\u81ea\u5168\u74031\u671f\u7814\u7a76\u7684\u4eba\u9ad4\u7814\u7a76\u6578\u64da\u3002<\/li>\n<li><b>\u827e\u52a0\u83ab\u5fb7\uff08<\/b><b>FcRn<\/b><b>\uff09<\/b>\uff1a\n<ul type=\"disc\">\n<li>\u773c\u808c\u578b\u91cd\u75c7\u808c\u7121\u529b\uff08oMG\uff09\uff1a2026\u5e742\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u7684\u5408\u4f5c\u5925\u4f34argenx\u5ba3\u4f48\uff0c\u5168\u74033\u671f\u7814\u7a76ADAPT OCULUS\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff08p\u503c=0.012\uff09\uff0c\u7814\u7a76\u8868\u660e\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0c\u827e\u52a0\u83ab\u5fb7\u6cbb\u7642\u7684oMG\u60a3\u8005\u5728\u7b2c\u56db\u5468\u6642\uff0c\u91cd\u75c7\u808c\u7121\u529b\u640d\u50b7\u6307\u6578\uff08MGII\uff09\u60a3\u8005\u5831\u544a\u7d50\u679c\uff08PRO\uff09\u773c\u90e8\u8a55\u5206\u81ea\u57fa\u7dda\u7684\u6539\u5584\u5177\u6709\u7d71\u8a08\u5b78\u4e0a\u7684\u986f\u8457\u6027\u3002\u5728\u7e3d\u4eba\u7fa4\u4e2d\uff0c\u827e\u52a0\u83ab\u5fb7\u6cbb\u7642\u7d44\u60a3\u8005\u7684MGII PRO\u8a55\u5206\u81ea\u57fa\u7dda\u7684\u5e73\u5747\u8b8a\u5316\u70ba\u6539\u55844.04\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d44\u60a3\u8005\u7684MGII PRO\u8a55\u5206\u5e73\u5747\u8b8a\u5316\u70ba\u6539\u55841.99\u5206\u3002\u63a5\u53d7\u827e\u52a0\u83ab\u5fb7\u6cbb\u7642\u7684\u60a3\u8005\u7684\u95dc\u9375\u773c\u90e8\u75c7\u72c0\uff0c\u5305\u62ec\u5fa9\u8996\u548c\u773c\u77bc\u4e0b\u5782\uff0c\u5747\u7372\u5f97\u986f\u8457\u6539\u5584\u3002\u5728oMG\u60a3\u8005\u4e2d\uff0c\u827e\u52a0\u83ab\u5fb7\u7684\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e14\u5b89\u5168\u6027\u7279\u5fb5\u826f\u597d\uff0c\u8207\u65e2\u5f80\u7814\u7a76\u4e00\u81f4\u3002\u518d\u9f0e\u91ab\u85e5\u5728\u5927\u4e2d\u83ef\u5340\uff08\u4e2d\u570b\u5167\u5730\u3001\u9999\u6e2f\u3001\u6fb3\u9580\u4ee5\u53ca\u53f0\u7063\u5730\u5340\uff09\u53c3\u8207\u4e86\u9019\u9805\u7814\u7a76\u3002<\/li>\n<li>\u8840\u6e05\u9670\u6027\u5168\u8eab\u578b\u91cd\u75c7\u808c\u7121\u529b\uff08sn-gMG\uff09\uff1a2026\u5e741\u6708\uff0cFDA\u53d7\u7406\u4e86\u827e\u52a0\u83ab\u5fb7\u7528\u65bc\u6cbb\u7642\u6297\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6297\u9ad4(AChR-Ab)sn-gMG\u6210\u4eba\u60a3\u8005\u7684\u88dc\u5145\u751f\u7269\u88fd\u54c1\u8a31\u53ef\u7533\u8acb\uff08sBLA\uff09\u7684\u512a\u5148\u5be9\u8a55\uff0c\u8655\u65b9\u85e5\u7528\u6236\u4ed8\u8cbb\u6cd5\u6848\u76ee\u6a19\u884c\u52d5\u65e5\u671f\uff08PDFUA\uff09\u70ba2026\u5e745\u670810\u65e5\u3002\u518d\u9f0e\u91ab\u85e5\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u4e86ADAPT SERON 3\u671f\u7814\u7a76\u3002<\/li>\n<\/ul>\n<\/li>\n<li><b>KarXT<\/b><b>\uff08\u546b\u8afe\u7f8e\u6797\u66f2\u53f8\u6c2f\u92a8\uff0c<\/b><b>M1\/M4<\/b><b>\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291<\/b><b>\uff09<\/b>\uff1a2025\u5e7412\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u6279\u51c6KarXT\u7528\u65bc\u6cbb\u7642\u6210\u4eba\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u3002KarXT\u662f70\u591a\u5e74\u4f86\u9996\u500b\u7372\u6279\u7684\u5177\u6709\u5275\u65b0\u4f5c\u7528\u6a5f\u5236\u7684\u7cbe\u795e\u5206\u88c2\u75c7\u7642\u6cd5\uff0c\u5e36\u4f86\u4e86\u5168\u65b0\u7684\u6cbb\u7642\u7bc4\u5f0f\u3002\u7522\u54c1\u8a08\u5283\u65bc2026\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u5728\u4e2d\u570b\u5546\u696d\u5316\u4e0a\u5e02\u3002<\/li>\n<li><b>Povetacicept (APRIL\/BAFF)<\/b><b>\uff1a<\/b>2025\u5e7412\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u52a0\u5165\u4e86\u7528\u65bc\u6cbb\u7642\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u7684\u5168\u7403\u95dc\u9375\u6027<b>2<\/b>\/<b>3<\/b>\u671fOLYMPUS\u7814\u7a76\uff0c\u4e26\u5728\u4e2d\u570b\u5167\u5730\u5b8c\u6210\u4e86\u9996\u4f8b\u60a3\u8005\u7d66\u85e5\u3002FDA\u6388\u4e88\u8a72\u7522\u54c1\u7528\u65bc\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u5feb\u901f\u901a\u9053\u548c\u5b64\u5152\u85e5\u8cc7\u683c\u8a8d\u5b9a\u3002EMA\u5df2\u6388\u4e88\u5176\u512a\u5148\u85e5\u54c1\uff08PRIME\uff09\u8cc7\u683c\u8a8d\u5b9a\u3002<\/li>\n<li><b>Elegrobart (<\/b><b>\u80f0\u5cf6\u7d20\u6a23\u751f\u9577\u56e0\u5b50<\/b><b>1<\/b><b>\u53d7\u9ad4\u6291\u5236\u5291<\/b><b>, <\/b><b>\u76ae\u4e0b\u6ce8\u5c04<\/b><b>):<\/b>\u00a02025\u5e7412\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5728\u4e2d\u570b\u5167\u5730\u555f\u52d5\u7528\u65bc\u6cbb\u7642\u7532\u72c0\u817a\u773c\u75c5\u7684\u8a3b\u518a\u6027\u7814\u7a76\u4e26\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7d66\u85e5\u3002\u5408\u4f5c\u5925\u4f34Viridian\u8a08\u5283\u57282026\u5e74\u4e0a\u534a\u5e74\u516c\u4f48\u5169\u9805\u5206\u5225\u91dd\u5c0d\u6d3b\u52d5\u6027\u7532\u72c0\u817a\u773c\u75c5\u548c\u6162\u6027\u7532\u72c0\u817a\u773c\u75c5\u60a3\u8005\u7684\u5168\u7403\u8a3b\u518a\u6027\u7814\u7a76\u7684\u4e3b\u8981\u7d50\u679c\u3002<\/li>\n<\/ul>\n<p><b><u>2026<\/u><\/b><b><u>\u5e74\u9810\u671f\u91cd\u8981\u91cc\u7a0b\u7891\u4e8b\u4ef6<\/u><\/b><\/p>\n<p><b><i>\u9810\u671f\u7684\u81e8\u5e8a\u958b\u767c\u548c\u6578\u64da\u516c\u4f48<\/i><\/b><\/p>\n<p><b><i>\u5168\u7403\u7ba1\u7dda<\/i><\/b><\/p>\n<p><b>Zocilurtatug Pelitecan (zoci, DLL3 ADC) (<\/b><b>\u524d\u7a31<\/b><b>ZL-1310)<\/b><\/p>\n<ul type=\"disc\">\n<li><i>\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5ee3\u6cdb\u671f\u5c0f\u7d30\u80de\u80ba\u764c\uff1a<\/i>\u00a0\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2026\u5e74\u4e0a\u534a\u5e74\u516c\u4f48\u6b63\u5728\u9032\u884c\u76841 \u671f\u81e8\u5e8a\u7814\u7a76\u4e2d\u9871\u5167\u6297\u816b\u7624\u6d3b\u6027\u7684\u6578\u64da\u66f4\u65b0\u3002<\/li>\n<li><i>\u4e00\u7dda\u5ee3\u6cdb\u671f\u5c0f\u7d30\u80de\u80ba\u764c\uff1a<\/i>\u00a0\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2026\u5e74\u4e0b\u534a\u5e74\u516c\u4f48\u8a55\u4f30zoci\u806f\u5408\u7642\u6cd5\uff08\u806f\u5408\u963f\u66ff\u5229\u73e0\u55ae\u6297\u00b1\u5316\u7642\uff09\u76841 \u671f\u7814\u7a76\u7684\u6578\u64da\u8b80\u51fa\uff0c\u4e26\u5c07\u57fa\u65bc\u6700\u65b0\u6578\u64da\u57282026\u5e74\u63a8\u9032\u81f3\u8a3b\u518a\u6027\u7814\u7a76\u968e\u6bb5\u3002\u518d\u9f0e\u91ab\u85e5\u9084\u8a08\u5283\u65bc2026\u5e74\u4e0a\u534a\u5e74\u555f\u52d5\u4e00\u98051 \u671f\u7814\u7a76\uff0c\u63a2\u7d22zoci\u7684\u65b0\u578b\u806f\u5408\u6cbb\u7642\u65b9\u6848\u3002<\/li>\n<li><i>\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c\uff1a<\/i>\u00a0\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2026\u5e74\u4e0a\u534a\u5e74\u516c\u4f48\u91dd\u5c0d\u7279\u5b9a\u5be6\u9ad4\u7624\u60a3\u8005\u7684\u5168\u7403\u00a01b\/2\u671f\u7814\u7a76\u4e2d1b\u671f\u90e8\u5206\u7684\u6578\u64da\u8b80\u51fa\uff0c\u4e26\u8a08\u5283\u57282026\u5e74\u63a8\u9032\u81f3\u8a3b\u518a\u6027\u958b\u767c\u968e\u6bb5\u3002<\/li>\n<\/ul>\n<p><b>ZL-1503 (IL-13\/IL-31R\u03b1)<\/b><\/p>\n<ul type=\"disc\">\n<li>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2026\u5e74\u516c\u4f48\u5168\u74031\/1b\u671f\u7814\u7a76\u7684\u9996\u6b21\u4eba\u9ad4\u7814\u7a76\u6578\u64da\u3002<\/li>\n<\/ul>\n<p><b><i>\u5340\u57df\u6b0a\u5229\u7ba1\u7dda<\/i><\/b><\/p>\n<p><b><i>\u8fd1\u671f\u6709\u671b\u7372\u5f97<\/i><\/b><b><i>NMPA<\/i><\/b><b><i>\u6279\u51c6\u7684\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb<\/i><\/b><\/p>\n<ul type=\"disc\">\n<li><b>\u7dad\u66ff\u7d22\u59a5\u5c24\u55ae\u6297\uff08\u7d44\u7e54\u56e0\u5b50<\/b><b>ADC<\/b><b>\uff09<\/b>\u00a0\u7528\u65bc\u5316\u7642\u671f\u9593\u6216\u4e4b\u5f8c\u75c5\u60c5\u9032\u5c55\u7684\u5fa9\u767c\u6216\u8f49\u79fb\u6027\u5bae\u9838\u764c<\/li>\n<li><b>\u816b\u7624\u96fb\u5834\u6cbb\u7642<\/b><b>(TTFields) <\/b>\u7528\u65bc\u5c40\u90e8\u665a\u671f\u80f0\u817a\u764c<\/li>\n<\/ul>\n<p><b>\u827e\u52a0\u83ab\u5fb7\uff08<\/b><b>FcRn\uff09<\/b><\/p>\n<ul type=\"disc\">\n<li><i>\u808c\u708e\uff1a<\/i>\u00a0\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34argenx\u5c07\u65bc2026\u5e74\u7b2c\u4e09\u5b63\u5ea6\u516c\u4f48\u8a55\u4f30\u81ea\u8eab\u514d\u75ab\u6027\u708e\u6027\u808c\u75c5\u5168\u74032\/3\u671fALKIVIA\u7814\u7a76\u7684\u4e3b\u8981\u7d50\u679c\u3002\u518d\u9f0e\u91ab\u85e5\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u4e86\u9019\u9805\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><b>Povetacicept (APRIL\/BAFF)<\/b><\/p>\n<ul type=\"disc\">\n<li><i>IgA\u00a0<\/i><i>\u814e\u75c5<\/i>\u00a0<i>(IgAN)<\/i>: \u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34Vertex\u6b63\u6309\u8a08\u5283\u63a8\u9032\uff0c\u5c07\u65bc2026\u5e74\u4e0a\u534a\u5e74\u516c\u4f48\u5168\u74033\u671fRAINIER\u7814\u7a76\u7684\u4e2d\u671f\u5206\u6790\u3002\u82e5\u4e2d\u671f\u5206\u6790\u6578\u64da\u652f\u6301\uff0c\u5c07\u65bc2026\u5e74\u4e0a\u534a\u5e74\u5b8c\u6210\u7533\u5831\u63d0\u4ea4\u3002FDA\u5df2\u6388\u4e88\u8a72\u9069\u61c9\u8b49\u7a81\u7834\u6027\u7642\u6cd5\u8a8d\u5b9a\u3002<\/li>\n<li><i>\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\uff1a<\/i>\u518d\u9f0e\u91ab\u85e5\u53ca\u5176\u5408\u4f5c\u5925\u4f34Vertex\u8a08\u5283\u65bc2026\u5e74\u5e74\u4e2d\u5b8c\u6210\u5168\u7403\u95dc\u9375\u60272\/3\u671fOLYMPUS\u7814\u7a76\u76842\u671f\u90e8\u5206\uff0c\u4e26\u555f\u52d53\u671f\u7814\u7a76\u3002<\/li>\n<\/ul>\n<p><b>Elegrobart<\/b><b>\u00a0(<\/b><b>anti-<\/b><b>IGF-1R, <\/b><b>\u76ae\u4e0b\u5291\u578b<\/b><b>)<\/b><\/p>\n<ul type=\"disc\">\n<li>Viridian\u5c07\u65bc2026\u5e74\u7b2c\u4e00\u5b63\u5ea6\u516c\u4f48\u7528\u65bc\u6d3b\u52d5\u6027TED\u60a3\u8005\u7684\u5168\u7403\u8a3b\u518a\u6027\u7814\u7a76REVEAL-1\u7684\u4e3b\u8981\u7d50\u679c\uff0c\u4e26\u65bc2026\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u516c\u4f48\u7528\u65bc\u6162\u6027TED\u7684\u5168\u7403\u8a3b\u518a\u6027\u7814\u7a76REVEAL-2\u7684\u4e3b\u8981\u7d50\u679c\u3002\u518d\u9f0e\u91ab\u85e5\u901a\u904e\u8207Zenas\u8a02\u7acb\u7684\u8a31\u53ef\u5354\u8b70\uff0c\u7372\u5f97\u4e86Viridian\u6297IGF-1R\u6297\u9ad4\u7684\u5206\u8a31\u53ef\uff0c\u4e26\u6b63\u5728\u63a8\u9032\u81e8\u5e8a\u958b\u767c\u3002<\/li>\n<\/ul>\n<p><b><u>\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u76f8\u95dc\u4fe1\u606f<\/u><\/b><\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc\u4eca\u5929\uff082026\u5e742\u670826\u65e5\uff09\u7f8e\u570b\u6771\u90e8\u6642\u9593\u4e0a\u53488\u9ede\uff08\u9999\u6e2f\u6642\u9593\u665a\u4e0a9\u9ede\uff09\u8209\u884c\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u3002\u8207\u6703\u8005\u53ef\u4ee5\u8a2a\u554f\u516c\u53f8\u7db2\u7ad9<a href=\"http:\/\/ir.zailaboratory.com%E5%8F%83%E8%88%87%E5%AF%A6%E6%99%82%E7%B6%B2%E7%B5%A1%E7%9B%B4%E6%92%AD\/\" rel=\"nofollow\" style=\"color: #0000FF\">http:\/\/ir.zailaboratory.com\u53c3\u8207\u5be6\u6642\u7db2\u7d61\u76f4\u64ad<\/a>\u3002\u5982\u8981\u53c3\u52a0\u96fb\u8a71\u6703\u8b70\uff0c\u9700\u63d0\u524d\u8a3b\u518a\u3002\u00a0<\/p>\n<p>\u8a73\u7d30\u4fe1\u606f\u5982\u4e0b\uff1a<br \/>\u7db2\u7d61\u76f4\u64ad\uff08\u63a8\u85a6\uff09\uff1a<a href=\"https:\/\/edge.media-server.com\/mmc\/p\/ftt8dzjp\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">https:\/\/edge.media-server.com\/mmc\/p\/ftt8dzjp<\/a><br \/>\u96fb\u8a71\u64a5\u5165\uff1a<a href=\"https:\/\/register-conf.media-server.com\/register\/BI3888301d591947ae8d0ccb041164c8e6\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">https:\/\/register-conf.media-server.com\/register\/BI3888301d591947ae8d0ccb041164c8e6<\/a><\/p>\n<p>\u6240\u6709\u8207\u6703\u8005\u90fd\u5fc5\u9808\u5728\u96fb\u8a71\u6703\u8b70\u4e4b\u524d\u901a\u904e\u4e0a\u65b9\u93c8\u63a5\u5b8c\u6210\u5728\u7dda\u8a3b\u518a\u3002\u8a3b\u518a\u6210\u529f\u5f8c\uff0c\u60a8\u5c07\u6536\u5230\u78ba\u8a8d\u90f5\u4ef6\uff0c\u5167\u542b\u64a5\u5165\u96fb\u8a71\u6703\u8b70\u7684\u5177\u9ad4\u4fe1\u606f\u3002\u00a0<\/p>\n<p>\u6703\u8b70\u7d50\u675f\u5f8c\uff0c\u60a8\u53ef\u901a\u904e\u8a2a\u554f\u518d\u9f0e\u91ab\u85e5\u7db2\u7ad9\u89c0\u770b\u56de\u653e\u3002\u00a0<\/p>\n<p><b>\u95dc\u65bc\u518d\u9f0e\u91ab\u85e5<\/b><\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\uff08\u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aZLAB\uff1b\u00a0\u9999\u6e2f\u806f\u4ea4\u6240\u80a1\u4efd\u4ee3\u865f\uff1a9688\uff09\u662f\u4e00\u5bb6\u4ee5\u7814\u767c\u70ba\u57fa\u790e\u3001\u8655\u65bc\u5546\u696d\u5316\u968e\u6bb5\u7684\u5275\u65b0\u578b\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u7e3d\u90e8\u4f4d\u65bc\u4e2d\u570b\u548c\u7f8e\u570b\u3002\u6211\u5011\u81f4\u529b\u65bc\u901a\u904e\u5275\u65b0\u7522\u54c1\u7684\u767c\u73fe\u3001\u958b\u767c\u548c\u5546\u696d\u5316\u89e3\u6c7a\u816b\u7624\u3001\u514d\u75ab\u3001\u795e\u7d93\u79d1\u5b78\u548c\u611f\u67d3\u6027\u75be\u75c5\u9818\u57df\u672a\u88ab\u6eff\u8db3\u7684\u5de8\u5927\u91ab\u7642\u9700\u6c42\u3002\u6211\u5011\u7684\u76ee\u6a19\u662f\u5229\u7528\u6211\u5011\u7684\u80fd\u529b\u548c\u8cc7\u6e90\u70ba\u4eba\u985e\u5065\u5eb7\u5e36\u4f86\u7a4d\u6975\u5f71\u97ff\u3002<\/p>\n<p>\u6709\u95dc\u518d\u9f0e\u91ab\u85e5\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f<a 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2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u7684\u7814\u767c\u958b\u652f\u70ba6,160\u842c\u7f8e\u5143\uff0c2024\u5e74\u540c\u671f\u70ba5,230\u842c\u7f8e\u5143\u30022025\u5e74\u5168\u5e74\u7814\u767c\u958b\u652f\u70ba2.209\u5104\u7f8e\u5143\uff0c2024\u5e74\u540c\u671f\u70ba2.345\u5104\u7f8e\u5143\u3002\u7b2c\u56db\u5b63\u5ea6\u7814\u767c\u958b\u652f\u7684\u589e\u52a0\u4e3b\u8981\u6e90\u65bc\u81e8\u5e8a\u7814\u7a76\u7684\u63a8\u9032\u3002\u5168\u5e74\u7814\u767c\u958b\u652f\u4e0b\u964d\u4e3b\u8981\u5f97\u76ca\u65bc\u6230\u7565\u8cc7\u6e90\u512a\u5316\u8abf\u6574\u5e36\u4f86\u7684\u4eba\u54e1\u6210\u672c\u4e0b\u964d\u3002  2025 \u5e74\u7b2c\u56db\u5b63\u5ea6\u7684\u92b7\u552e\u3001\u4e00\u822c\u53ca\u884c\u653f (SG&amp;A) \u958b\u652f\u70ba 7,300 \u842c\u7f8e\u5143\uff0c2024 \u5e74\u540c\u671f\u70ba8,260 \u842c\u7f8e\u5143\u30022025\u5e74\u5168\u5e74\u7684SG&amp;A\u958b\u652f\u70ba 2.776 \u5104\u7f8e\u5143\uff0c 2024 \u5e74\u540c\u671f\u70ba 2.987 \u5104\u7f8e\u5143\u3002\u9019\u4e00\u4e0b\u964d\u4e3b\u8981\u7531\u65bc\u6230\u7565\u8cc7\u6e90\u512a\u5316\u8abf\u6574\u6240\u5e36\u4f86\u4e00\u822c\u53ca\u884c\u653f\u958b\u652f\u7684\u4e0b\u964d\u3002  2025 \u5e74\u7b2c\u56db\u5b63\u5ea6\u548c 2025 \u5e74\u5168\u5e74\u7684\u7d93\u71df\u8667\u640d\u5206\u5225\u70ba 6,940 \u842c\u7f8e\u5143\u548c 2.294 \u5104\u7f8e\u5143\uff0c\u7d93\u8abf\u6574\u6263\u9664\u6298\u820a\u3001\u6524\u92b7\u548c\u4ee5\u80a1\u4efd\u70ba\u57fa\u790e\u7684\u916c\u91d1\u7b49\u975e\u73fe\u91d1\u652f\u51fa\u5f8c\u5206\u5225\u70ba4,960\u842c\u7f8e\u5143\u548c1.488\u5104\u7f8e\u5143\uff0c2024 \u5e74\u7b2c\u56db\u5b63\u5ea6\u548c 2024 \u5e74\u5168\u5e74\u7684\u7d93\u71df\u8667\u640d\u5206\u5225\u70ba6,790\u842c\u7f8e\u5143\u548c2.821\u5104\u7f8e\u5143\u3002\u672c\u65b0\u805e\u7a3f\u672b\u5c3e\u9644\u6709\u7d93\u71df\u8667\u640d\uff08\u7f8e\u570b\u516c\u8a8d\u6703\u8a08\u6e96\u5247\uff09\u548c\u8abf\u6574\u5f8c\u7684\u7d93\u71df\u8667\u640d\uff08\u975e\u7f8e\u570b\u516c\u8a8d\u6703\u8a08\u6e96\u5247\uff09\u7684\u5c0d\u6bd4\u3002  2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u8667\u640d\u6de8\u984d\u70ba 5,040 \u842c\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.05\u7f8e\u5143\uff08\u6bcf\u4efd\u7f8e\u570b\u5b58\u6258\u80a1\u4efd\uff08ADS\uff09\u8667\u640d\u70ba0.46\u7f8e\u5143\uff09\uff0c2024 \u5e74\u540c\u671f\u8667\u640d\u6de8\u984d\u70ba 8,170 \u842c\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.08\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba0.80 \u7f8e\u5143\uff09\u30022025 \u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 1.755 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.16\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba1.60\u7f8e\u5143\uff09\uff0c2024 \u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 2.571 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.26\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba2.60\u7f8e\u5143\uff09\u3002\u8667\u640d\u6de8\u984d\u6e1b\u5c11\u4e3b\u8981\u662f\u7531\u65bc\u7522\u54c1\u6536\u5165\u589e\u9577\u5feb\u65bc\u904b\u71df\u958b\u652f\u4ee5\u53ca\u532f\u514c\u640d\u5931\u8f49\u70ba\u532f\u514c\u6536\u76ca\uff0c\u4f46\u88ab\u5229\u606f\u6536\u76ca\u6e1b\u5c11\u6240\u62b5\u92b7\u3002  \u622a\u81f3 2025 \u5e74 12 \u6708 31 \u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u548c\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba 7.896 \u5104\u7f8e\u5143\uff0c\u622a\u81f3 2024 \u5e74 12 \u6708 31 \u65e5\u70ba 8.797\u5104\u7f8e\u5143\u3002  2026\u5e74\u6230\u7565\u91cd\u9ede \u518d\u9f0e\u91ab\u85e5\u57282026\u5e74\u5c07\u805a\u7126\u4ee5\u4e0b\u6230\u7565\u91cd\u9ede\uff0c\u4ee5\u9a45\u52d5\u8fd1\u671f\u696d\u7e3e\u8207\u9577\u671f\u5168\u7403\u50f9\u503c\u7684\u63d0\u5347\uff1a \u63a8\u9032\u816b\u7624\u548c\u514d\u75ab\u9818\u57df\u5dee\u7570\u5316\u7684\u5168\u7403\u9805\u76ee   Zocilurtatug pelitecan (zoci) (\u9776\u5411DLL3 ADC): \u81f32026\u5e74\u5e95\uff0c\u63a8\u9032\u57282L+ SCLC\u30011L SCLC\u53ca\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c(NECs)\u9818\u57df\u7684\u4e09\u9805\u8a3b\u518a\u6027\u95dc\u9375\u7814\u7a76\u30022026\u5e74\u5167\u9810\u8a08\u5c07\u6709\u4e09\u9805\u6578\u64da\u8b80\u51fa\uff0c\u5305\u62ec\uff1a     2L+ SCLC: \u66f4\u65b0\u7684\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\uff0c\u4ee5\u5c55\u793a\u5728\u4f34\u6709\u8166\u8f49\u79fb\u7684\u60a3\u8005\u4e2d\u7684\u9871\u5167\u7de9\u89e3\u6548\u679c   1L SCLC: \u6b63\u5728\u9032\u884c\u76841\u671f\u7814\u7a76\u6578\u64da\uff0c\u8a55\u4f30\u8207PD-L1\u6291\u5236\u5291\u00b1\u5316\u7642\u806f\u5408\u7684\u96d9\u806f\u53ca\u4e09\u806f\u65b9\u6848\uff1b\u555f\u52d5\u8207\u65b0\u578b\u7642\u6cd5\u65b9\u6848\u806f\u7528\u7684\u5168\u74031\u671f\u7814\u7a76   \u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c\uff1a\u4f86\u81ea\u6b63\u5728\u9032\u884c\u7684\u5168\u74031b\/2\u671f\u7814\u7a76\u4e2d1b\u671f\u90e8\u5206\u7684\u6578\u64da    ZL-1503 (IL-13\/IL-31 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Viridian\u5c07\u65bc2026\u5e74\u7b2c\u4e00\u5b63\u5ea6\u516c\u4f48\u7528\u65bc\u6d3b\u52d5\u6027TED\u60a3\u8005\u7684\u5168\u7403\u8a3b\u518a\u6027\u7814\u7a76REVEAL-1\u7684\u4e3b\u8981\u7d50\u679c\uff0c\u4e26\u65bc2026\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u516c\u4f48\u7528\u65bc\u6162\u6027TED\u7684\u5168\u7403\u8a3b\u518a\u6027\u7814\u7a76REVEAL-2\u7684\u4e3b\u8981\u7d50\u679c\u3002\u518d\u9f0e\u91ab\u85e5\u901a\u904e\u8207Zenas\u8a02\u7acb\u7684\u8a31\u53ef\u5354\u8b70\uff0c\u7372\u5f97\u4e86Viridian\u6297IGF-1R\u6297\u9ad4\u7684\u5206\u8a31\u53ef\uff0c\u4e26\u6b63\u5728\u63a8\u9032\u81e8\u5e8a\u958b\u767c\u3002  \u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u76f8\u95dc\u4fe1\u606f 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\u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u548c\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba 7.896 \u5104\u7f8e\u5143\uff0c\u622a\u81f3 2024 \u5e74 12 \u6708 31 \u65e5\u70ba 8.797\u5104\u7f8e\u5143\u3002  2026\u5e74\u6230\u7565\u91cd\u9ede \u518d\u9f0e\u91ab\u85e5\u57282026\u5e74\u5c07\u805a\u7126\u4ee5\u4e0b\u6230\u7565\u91cd\u9ede\uff0c\u4ee5\u9a45\u52d5\u8fd1\u671f\u696d\u7e3e\u8207\u9577\u671f\u5168\u7403\u50f9\u503c\u7684\u63d0\u5347\uff1a \u63a8\u9032\u816b\u7624\u548c\u514d\u75ab\u9818\u57df\u5dee\u7570\u5316\u7684\u5168\u7403\u9805\u76ee   Zocilurtatug pelitecan (zoci) (\u9776\u5411DLL3 ADC): \u81f32026\u5e74\u5e95\uff0c\u63a8\u9032\u57282L+ SCLC\u30011L SCLC\u53ca\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c(NECs)\u9818\u57df\u7684\u4e09\u9805\u8a3b\u518a\u6027\u95dc\u9375\u7814\u7a76\u30022026\u5e74\u5167\u9810\u8a08\u5c07\u6709\u4e09\u9805\u6578\u64da\u8b80\u51fa\uff0c\u5305\u62ec\uff1a     2L+ SCLC: \u66f4\u65b0\u7684\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\uff0c\u4ee5\u5c55\u793a\u5728\u4f34\u6709\u8166\u8f49\u79fb\u7684\u60a3\u8005\u4e2d\u7684\u9871\u5167\u7de9\u89e3\u6548\u679c   1L SCLC: \u6b63\u5728\u9032\u884c\u76841\u671f\u7814\u7a76\u6578\u64da\uff0c\u8a55\u4f30\u8207PD-L1\u6291\u5236\u5291\u00b1\u5316\u7642\u806f\u5408\u7684\u96d9\u806f\u53ca\u4e09\u806f\u65b9\u6848\uff1b\u555f\u52d5\u8207\u65b0\u578b\u7642\u6cd5\u65b9\u6848\u806f\u7528\u7684\u5168\u74031\u671f\u7814\u7a76   \u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c\uff1a\u4f86\u81ea\u6b63\u5728\u9032\u884c\u7684\u5168\u74031b\/2\u671f\u7814\u7a76\u4e2d1b\u671f\u90e8\u5206\u7684\u6578\u64da    ZL-1503 (IL-13\/IL-31 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ADC):\u00a0     \u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5ee3\u6cdb\u671f\u5c0f\u7d30\u80de\u80ba\u764c\uff1a\u8a55\u4f30zoci\u5c0d\u6bd4\u7814\u7a76\u8005\u9078\u64c7\u7684\u6cbb\u7642\u65b9\u6848\uff08\u6258\u6cca\u66ff\u5eb7\u3001\u8606\u6bd4\u66ff\u5b9a\u6216\u6c28\u67d4\u6bd4\u661f\uff09\u5728\u5fa9\u767c\u6027\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\u4e2d\u7684\u7642\u6548\u548c\u5b89\u5168\u6027\u7684\u5168\u7403\u00a03\u671f\u7814\u7a76\u6b63\u5728\u9032\u884c\u4e2d\u3002\u9019\u9805\u95dc\u9375\u6027\u7814\u7a76\u8a08\u5283\u5165\u7d44\u7d04480\u540d\u4e8c\u7ddaSCLC\u6216tarlatamab\u7d93\u6cbb\u7684\u4e09\u7dda\u00a0SCLC\u60a3\u8005\uff0c\u5927\u90e8\u5206\u5165\u7d44\u9810\u8a08\u5728\u4eca\u5e74\u5b8c\u6210\u3002   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\u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 1.755 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.16\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba1.60\u7f8e\u5143\uff09\uff0c2024 \u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 2.571 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.26\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba2.60\u7f8e\u5143\uff09\u3002\u8667\u640d\u6de8\u984d\u6e1b\u5c11\u4e3b\u8981\u662f\u7531\u65bc\u7522\u54c1\u6536\u5165\u589e\u9577\u5feb\u65bc\u904b\u71df\u958b\u652f\u4ee5\u53ca\u532f\u514c\u640d\u5931\u8f49\u70ba\u532f\u514c\u6536\u76ca\uff0c\u4f46\u88ab\u5229\u606f\u6536\u76ca\u6e1b\u5c11\u6240\u62b5\u92b7\u3002 \u622a\u81f3 2025 \u5e74 12 \u6708 31 \u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u548c\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba 7.896 \u5104\u7f8e\u5143\uff0c\u622a\u81f3 2024 \u5e74 12 \u6708 31 \u65e5\u70ba 8.797\u5104\u7f8e\u5143\u3002 2026\u5e74\u6230\u7565\u91cd\u9ede \u518d\u9f0e\u91ab\u85e5\u57282026\u5e74\u5c07\u805a\u7126\u4ee5\u4e0b\u6230\u7565\u91cd\u9ede\uff0c\u4ee5\u9a45\u52d5\u8fd1\u671f\u696d\u7e3e\u8207\u9577\u671f\u5168\u7403\u50f9\u503c\u7684\u63d0\u5347\uff1a \u63a8\u9032\u816b\u7624\u548c\u514d\u75ab\u9818\u57df\u5dee\u7570\u5316\u7684\u5168\u7403\u9805\u76ee Zocilurtatug pelitecan (zoci) (\u9776\u5411DLL3 ADC): \u81f32026\u5e74\u5e95\uff0c\u63a8\u9032\u57282L+ SCLC\u30011L SCLC\u53ca\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c(NECs)\u9818\u57df\u7684\u4e09\u9805\u8a3b\u518a\u6027\u95dc\u9375\u7814\u7a76\u30022026\u5e74\u5167\u9810\u8a08\u5c07\u6709\u4e09\u9805\u6578\u64da\u8b80\u51fa\uff0c\u5305\u62ec\uff1a 2L+ SCLC: \u66f4\u65b0\u7684\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\uff0c\u4ee5\u5c55\u793a\u5728\u4f34\u6709\u8166\u8f49\u79fb\u7684\u60a3\u8005\u4e2d\u7684\u9871\u5167\u7de9\u89e3\u6548\u679c 1L SCLC: \u6b63\u5728\u9032\u884c\u76841\u671f\u7814\u7a76\u6578\u64da\uff0c\u8a55\u4f30\u8207PD-L1\u6291\u5236\u5291\u00b1\u5316\u7642\u806f\u5408\u7684\u96d9\u806f\u53ca\u4e09\u806f\u65b9\u6848\uff1b\u555f\u52d5\u8207\u65b0\u578b\u7642\u6cd5\u65b9\u6848\u806f\u7528\u7684\u5168\u74031\u671f\u7814\u7a76 \u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c\uff1a\u4f86\u81ea\u6b63\u5728\u9032\u884c\u7684\u5168\u74031b\\\/2\u671f\u7814\u7a76\u4e2d1b\u671f\u90e8\u5206\u7684\u6578\u64da ZL-1503 (IL-13\\\/IL-31 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2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u7684\u7814\u767c\u958b\u652f\u70ba6,160\u842c\u7f8e\u5143\uff0c2024\u5e74\u540c\u671f\u70ba5,230\u842c\u7f8e\u5143\u30022025\u5e74\u5168\u5e74\u7814\u767c\u958b\u652f\u70ba2.209\u5104\u7f8e\u5143\uff0c2024\u5e74\u540c\u671f\u70ba2.345\u5104\u7f8e\u5143\u3002\u7b2c\u56db\u5b63\u5ea6\u7814\u767c\u958b\u652f\u7684\u589e\u52a0\u4e3b\u8981\u6e90\u65bc\u81e8\u5e8a\u7814\u7a76\u7684\u63a8\u9032\u3002\u5168\u5e74\u7814\u767c\u958b\u652f\u4e0b\u964d\u4e3b\u8981\u5f97\u76ca\u65bc\u6230\u7565\u8cc7\u6e90\u512a\u5316\u8abf\u6574\u5e36\u4f86\u7684\u4eba\u54e1\u6210\u672c\u4e0b\u964d\u3002  2025 \u5e74\u7b2c\u56db\u5b63\u5ea6\u7684\u92b7\u552e\u3001\u4e00\u822c\u53ca\u884c\u653f (SG&amp;A) \u958b\u652f\u70ba 7,300 \u842c\u7f8e\u5143\uff0c2024 \u5e74\u540c\u671f\u70ba8,260 \u842c\u7f8e\u5143\u30022025\u5e74\u5168\u5e74\u7684SG&amp;A\u958b\u652f\u70ba 2.776 \u5104\u7f8e\u5143\uff0c 2024 \u5e74\u540c\u671f\u70ba 2.987 \u5104\u7f8e\u5143\u3002\u9019\u4e00\u4e0b\u964d\u4e3b\u8981\u7531\u65bc\u6230\u7565\u8cc7\u6e90\u512a\u5316\u8abf\u6574\u6240\u5e36\u4f86\u4e00\u822c\u53ca\u884c\u653f\u958b\u652f\u7684\u4e0b\u964d\u3002  2025 \u5e74\u7b2c\u56db\u5b63\u5ea6\u548c 2025 \u5e74\u5168\u5e74\u7684\u7d93\u71df\u8667\u640d\u5206\u5225\u70ba 6,940 \u842c\u7f8e\u5143\u548c 2.294 \u5104\u7f8e\u5143\uff0c\u7d93\u8abf\u6574\u6263\u9664\u6298\u820a\u3001\u6524\u92b7\u548c\u4ee5\u80a1\u4efd\u70ba\u57fa\u790e\u7684\u916c\u91d1\u7b49\u975e\u73fe\u91d1\u652f\u51fa\u5f8c\u5206\u5225\u70ba4,960\u842c\u7f8e\u5143\u548c1.488\u5104\u7f8e\u5143\uff0c2024 \u5e74\u7b2c\u56db\u5b63\u5ea6\u548c 2024 \u5e74\u5168\u5e74\u7684\u7d93\u71df\u8667\u640d\u5206\u5225\u70ba6,790\u842c\u7f8e\u5143\u548c2.821\u5104\u7f8e\u5143\u3002\u672c\u65b0\u805e\u7a3f\u672b\u5c3e\u9644\u6709\u7d93\u71df\u8667\u640d\uff08\u7f8e\u570b\u516c\u8a8d\u6703\u8a08\u6e96\u5247\uff09\u548c\u8abf\u6574\u5f8c\u7684\u7d93\u71df\u8667\u640d\uff08\u975e\u7f8e\u570b\u516c\u8a8d\u6703\u8a08\u6e96\u5247\uff09\u7684\u5c0d\u6bd4\u3002  2025\u5e74\u7b2c\u56db\u5b63\u5ea6\u8667\u640d\u6de8\u984d\u70ba 5,040 \u842c\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.05\u7f8e\u5143\uff08\u6bcf\u4efd\u7f8e\u570b\u5b58\u6258\u80a1\u4efd\uff08ADS\uff09\u8667\u640d\u70ba0.46\u7f8e\u5143\uff09\uff0c2024 \u5e74\u540c\u671f\u8667\u640d\u6de8\u984d\u70ba 8,170 \u842c\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.08\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba0.80 \u7f8e\u5143\uff09\u30022025 \u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 1.755 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.16\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba1.60\u7f8e\u5143\uff09\uff0c2024 \u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 2.571 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.26\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba2.60\u7f8e\u5143\uff09\u3002\u8667\u640d\u6de8\u984d\u6e1b\u5c11\u4e3b\u8981\u662f\u7531\u65bc\u7522\u54c1\u6536\u5165\u589e\u9577\u5feb\u65bc\u904b\u71df\u958b\u652f\u4ee5\u53ca\u532f\u514c\u640d\u5931\u8f49\u70ba\u532f\u514c\u6536\u76ca\uff0c\u4f46\u88ab\u5229\u606f\u6536\u76ca\u6e1b\u5c11\u6240\u62b5\u92b7\u3002  \u622a\u81f3 2025 \u5e74 12 \u6708 31 \u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u548c\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba 7.896 \u5104\u7f8e\u5143\uff0c\u622a\u81f3 2024 \u5e74 12 \u6708 31 \u65e5\u70ba 8.797\u5104\u7f8e\u5143\u3002  2026\u5e74\u6230\u7565\u91cd\u9ede \u518d\u9f0e\u91ab\u85e5\u57282026\u5e74\u5c07\u805a\u7126\u4ee5\u4e0b\u6230\u7565\u91cd\u9ede\uff0c\u4ee5\u9a45\u52d5\u8fd1\u671f\u696d\u7e3e\u8207\u9577\u671f\u5168\u7403\u50f9\u503c\u7684\u63d0\u5347\uff1a \u63a8\u9032\u816b\u7624\u548c\u514d\u75ab\u9818\u57df\u5dee\u7570\u5316\u7684\u5168\u7403\u9805\u76ee   Zocilurtatug pelitecan (zoci) (\u9776\u5411DLL3 ADC): \u81f32026\u5e74\u5e95\uff0c\u63a8\u9032\u57282L+ SCLC\u30011L SCLC\u53ca\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c(NECs)\u9818\u57df\u7684\u4e09\u9805\u8a3b\u518a\u6027\u95dc\u9375\u7814\u7a76\u30022026\u5e74\u5167\u9810\u8a08\u5c07\u6709\u4e09\u9805\u6578\u64da\u8b80\u51fa\uff0c\u5305\u62ec\uff1a     2L+ SCLC: \u66f4\u65b0\u7684\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\uff0c\u4ee5\u5c55\u793a\u5728\u4f34\u6709\u8166\u8f49\u79fb\u7684\u60a3\u8005\u4e2d\u7684\u9871\u5167\u7de9\u89e3\u6548\u679c   1L SCLC: \u6b63\u5728\u9032\u884c\u76841\u671f\u7814\u7a76\u6578\u64da\uff0c\u8a55\u4f30\u8207PD-L1\u6291\u5236\u5291\u00b1\u5316\u7642\u806f\u5408\u7684\u96d9\u806f\u53ca\u4e09\u806f\u65b9\u6848\uff1b\u555f\u52d5\u8207\u65b0\u578b\u7642\u6cd5\u65b9\u6848\u806f\u7528\u7684\u5168\u74031\u671f\u7814\u7a76   \u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c\uff1a\u4f86\u81ea\u6b63\u5728\u9032\u884c\u7684\u5168\u74031b\/2\u671f\u7814\u7a76\u4e2d1b\u671f\u90e8\u5206\u7684\u6578\u64da    ZL-1503 (IL-13\/IL-31 R\u03b1\u96d9\u7279\u7570\u6027\u6297\u9ad4)\uff1a\u9810\u8a08\u57282026\u5e74\u4e0b\u534a\u5e74\u516c\u4f48\u6b63\u5728\u9032\u884c\u7684\u5168\u74031\/1b\u671f\u7814\u7a76\u7684\u9996\u6b21\u4eba\u9ad4(FIH)\u6578\u64da\uff0c\u70ba\u7528\u65bc\u7279\u61c9\u6027\u76ae\u708e(AD)\u76842\u671f\u81e8\u5e8a\u958b\u767c\u5960\u5b9a\u57fa\u790e\u3002  ZL-6201 (\u9776\u5411LRRC15 ADC) \uff1a\u5168\u74031\u671f\u7814\u7a76\u6b63\u5728\u9032\u884c\u4e2d\u3002  ZL-1222 (PD-1\/IL-12\u514d\u75ab\u7d30\u80de\u56e0\u5b50)\uff1a\u65b0\u85e5\u81e8\u5e8a\u8a66\u9a57\u7533\u8acb(IND)\u652f\u6301\u6027\u7814\u7a76\u9810\u8a08\u65bc2026\u5e74\u5b8c\u6210\u3002  ZL-1311\u00a0(\u9776\u5411MUC17\u7684T\u7d30\u80de\u929c\u63a5\u5668(TCE))\uff1a\u9810\u8a08\u5e74\u5e95\u524d\u63d0\u4ea4IND\u3002  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KarXT\uff1a\u8a08\u5283\u65bc2026\u5e74\u4e0a\u534a\u5e74\u5546\u696d\u5316\u4e0a\u5e02\uff0c\u7a4d\u6975\u958b\u5c55\u91dd\u5c0d\u6027\u5546\u696d\u5316\u7b56\u7565\u3001\u91ab\u751f\u6559\u80b2\u3001\u771f\u5be6\u4e16\u754c\u8b49\u64da\u751f\u6210\uff0c\u4e26\u70ba\u53ef\u80fd\u65bc2027\u5e74\u7d0d\u5165NRDL\u505a\u597d\u6e96\u5099\u3002  Povetacicept\u548celegrobart\u00a0\uff1a\u5747\u9810\u8a08\u57282026\u5e74\u7372\u5f97\u95dc\u9375\u6027\u6578\u64da\u8b80\u51fa\uff0c\u6709\u671b\u65bc\u8fd1\u671f\u9032\u4e00\u6b65\u9a45\u52d5\u5340\u57df\u6027\u6536\u5165\u7684\u589e\u9577\u3002  \u91cd\u8981\u516c\u53f8\u9032\u5c55 \u81ea\u4e0a\u6b21\u8ca1\u5831\u767c\u4f48\u4ee5\u4f86\u518d\u9f0e\u91ab\u85e5\u7684\u95dc\u9375\u516c\u53f8\u9032\u5c55\u5305\u62ec\uff1a   \u696d\u52d9\u62d3\u5c55\uff1a    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\u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u548c\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba 7.896 \u5104\u7f8e\u5143\uff0c\u622a\u81f3 2024 \u5e74 12 \u6708 31 \u65e5\u70ba 8.797\u5104\u7f8e\u5143\u3002  2026\u5e74\u6230\u7565\u91cd\u9ede \u518d\u9f0e\u91ab\u85e5\u57282026\u5e74\u5c07\u805a\u7126\u4ee5\u4e0b\u6230\u7565\u91cd\u9ede\uff0c\u4ee5\u9a45\u52d5\u8fd1\u671f\u696d\u7e3e\u8207\u9577\u671f\u5168\u7403\u50f9\u503c\u7684\u63d0\u5347\uff1a \u63a8\u9032\u816b\u7624\u548c\u514d\u75ab\u9818\u57df\u5dee\u7570\u5316\u7684\u5168\u7403\u9805\u76ee   Zocilurtatug pelitecan (zoci) (\u9776\u5411DLL3 ADC): \u81f32026\u5e74\u5e95\uff0c\u63a8\u9032\u57282L+ SCLC\u30011L SCLC\u53ca\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c(NECs)\u9818\u57df\u7684\u4e09\u9805\u8a3b\u518a\u6027\u95dc\u9375\u7814\u7a76\u30022026\u5e74\u5167\u9810\u8a08\u5c07\u6709\u4e09\u9805\u6578\u64da\u8b80\u51fa\uff0c\u5305\u62ec\uff1a     2L+ SCLC: \u66f4\u65b0\u7684\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\uff0c\u4ee5\u5c55\u793a\u5728\u4f34\u6709\u8166\u8f49\u79fb\u7684\u60a3\u8005\u4e2d\u7684\u9871\u5167\u7de9\u89e3\u6548\u679c   1L SCLC: \u6b63\u5728\u9032\u884c\u76841\u671f\u7814\u7a76\u6578\u64da\uff0c\u8a55\u4f30\u8207PD-L1\u6291\u5236\u5291\u00b1\u5316\u7642\u806f\u5408\u7684\u96d9\u806f\u53ca\u4e09\u806f\u65b9\u6848\uff1b\u555f\u52d5\u8207\u65b0\u578b\u7642\u6cd5\u65b9\u6848\u806f\u7528\u7684\u5168\u74031\u671f\u7814\u7a76   \u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c\uff1a\u4f86\u81ea\u6b63\u5728\u9032\u884c\u7684\u5168\u74031b\/2\u671f\u7814\u7a76\u4e2d1b\u671f\u90e8\u5206\u7684\u6578\u64da    ZL-1503 (IL-13\/IL-31 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ADC):\u00a0     \u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5ee3\u6cdb\u671f\u5c0f\u7d30\u80de\u80ba\u764c\uff1a\u8a55\u4f30zoci\u5c0d\u6bd4\u7814\u7a76\u8005\u9078\u64c7\u7684\u6cbb\u7642\u65b9\u6848\uff08\u6258\u6cca\u66ff\u5eb7\u3001\u8606\u6bd4\u66ff\u5b9a\u6216\u6c28\u67d4\u6bd4\u661f\uff09\u5728\u5fa9\u767c\u6027\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\u4e2d\u7684\u7642\u6548\u548c\u5b89\u5168\u6027\u7684\u5168\u7403\u00a03\u671f\u7814\u7a76\u6b63\u5728\u9032\u884c\u4e2d\u3002\u9019\u9805\u95dc\u9375\u6027\u7814\u7a76\u8a08\u5283\u5165\u7d44\u7d04480\u540d\u4e8c\u7ddaSCLC\u6216tarlatamab\u7d93\u6cbb\u7684\u4e09\u7dda\u00a0SCLC\u60a3\u8005\uff0c\u5927\u90e8\u5206\u5165\u7d44\u9810\u8a08\u5728\u4eca\u5e74\u5b8c\u6210\u3002   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\u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 1.755 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.16\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba1.60\u7f8e\u5143\uff09\uff0c2024 \u5e74\u5168\u5e74\u8667\u640d\u6de8\u984d\u70ba 2.571 \u5104\u7f8e\u5143\uff0c\u6b78\u5c6c\u65bc\u666e\u901a\u80a1\u80a1\u6771\u7684\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d 0.26\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba2.60\u7f8e\u5143\uff09\u3002\u8667\u640d\u6de8\u984d\u6e1b\u5c11\u4e3b\u8981\u662f\u7531\u65bc\u7522\u54c1\u6536\u5165\u589e\u9577\u5feb\u65bc\u904b\u71df\u958b\u652f\u4ee5\u53ca\u532f\u514c\u640d\u5931\u8f49\u70ba\u532f\u514c\u6536\u76ca\uff0c\u4f46\u88ab\u5229\u606f\u6536\u76ca\u6e1b\u5c11\u6240\u62b5\u92b7\u3002 \u622a\u81f3 2025 \u5e74 12 \u6708 31 \u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u548c\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba 7.896 \u5104\u7f8e\u5143\uff0c\u622a\u81f3 2024 \u5e74 12 \u6708 31 \u65e5\u70ba 8.797\u5104\u7f8e\u5143\u3002 2026\u5e74\u6230\u7565\u91cd\u9ede \u518d\u9f0e\u91ab\u85e5\u57282026\u5e74\u5c07\u805a\u7126\u4ee5\u4e0b\u6230\u7565\u91cd\u9ede\uff0c\u4ee5\u9a45\u52d5\u8fd1\u671f\u696d\u7e3e\u8207\u9577\u671f\u5168\u7403\u50f9\u503c\u7684\u63d0\u5347\uff1a \u63a8\u9032\u816b\u7624\u548c\u514d\u75ab\u9818\u57df\u5dee\u7570\u5316\u7684\u5168\u7403\u9805\u76ee Zocilurtatug pelitecan (zoci) (\u9776\u5411DLL3 ADC): \u81f32026\u5e74\u5e95\uff0c\u63a8\u9032\u57282L+ SCLC\u30011L SCLC\u53ca\u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c(NECs)\u9818\u57df\u7684\u4e09\u9805\u8a3b\u518a\u6027\u95dc\u9375\u7814\u7a76\u30022026\u5e74\u5167\u9810\u8a08\u5c07\u6709\u4e09\u9805\u6578\u64da\u8b80\u51fa\uff0c\u5305\u62ec\uff1a 2L+ SCLC: \u66f4\u65b0\u7684\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\uff0c\u4ee5\u5c55\u793a\u5728\u4f34\u6709\u8166\u8f49\u79fb\u7684\u60a3\u8005\u4e2d\u7684\u9871\u5167\u7de9\u89e3\u6548\u679c 1L SCLC: \u6b63\u5728\u9032\u884c\u76841\u671f\u7814\u7a76\u6578\u64da\uff0c\u8a55\u4f30\u8207PD-L1\u6291\u5236\u5291\u00b1\u5316\u7642\u806f\u5408\u7684\u96d9\u806f\u53ca\u4e09\u806f\u65b9\u6848\uff1b\u555f\u52d5\u8207\u65b0\u578b\u7642\u6cd5\u65b9\u6848\u806f\u7528\u7684\u5168\u74031\u671f\u7814\u7a76 \u80ba\u5916\u795e\u7d93\u5167\u5206\u6ccc\u764c\uff1a\u4f86\u81ea\u6b63\u5728\u9032\u884c\u7684\u5168\u74031b\/2\u671f\u7814\u7a76\u4e2d1b\u671f\u90e8\u5206\u7684\u6578\u64da ZL-1503 (IL-13\/IL-31 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2025\u5e7412\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u5967\u51f1\u6a02\u00ae\u7528\u65bc\u6cbb\u7642\u651c\u5e36\u795e\u7d93\u71df\u990a\u916a\u6c28\u9178\u53d7\u9ad4\u6fc0\u9176\uff08NTRK\uff09\u57fa\u56e0\u878d\u5408\u7684\u5be6\u9ad4\u7624\u6210\u4eba\u60a3\u8005\u7684\u88dc\u5145\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff08sNDA\uff09\u3002 \u514d\u75ab\u3001\u795e\u7d93\u79d1\u5b78\u53ca\u611f\u67d3\u6027\u75be\u75c5\u9818\u57df\u7ba1\u7dda ZL-1503\uff08IL-13\/IL-31 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PRO\u8a55\u5206\u5e73\u5747\u8b8a\u5316\u70ba\u6539\u55841.99\u5206\u3002\u63a5\u53d7\u827e\u52a0\u83ab\u5fb7\u6cbb\u7642\u7684\u60a3\u8005\u7684\u95dc\u9375\u773c\u90e8\u75c7\u72c0\uff0c\u5305\u62ec\u5fa9\u8996\u548c\u773c\u77bc\u4e0b\u5782\uff0c\u5747\u7372\u5f97\u986f\u8457\u6539\u5584\u3002\u5728oMG\u60a3\u8005\u4e2d\uff0c\u827e\u52a0\u83ab\u5fb7\u7684\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e14\u5b89\u5168\u6027\u7279\u5fb5\u826f\u597d\uff0c\u8207\u65e2\u5f80\u7814\u7a76\u4e00\u81f4\u3002\u518d\u9f0e\u91ab\u85e5\u5728\u5927\u4e2d\u83ef\u5340\uff08\u4e2d\u570b\u5167\u5730\u3001\u9999\u6e2f\u3001\u6fb3\u9580\u4ee5\u53ca\u53f0\u7063\u5730\u5340\uff09\u53c3\u8207\u4e86\u9019\u9805\u7814\u7a76\u3002 \u8840\u6e05\u9670\u6027\u5168\u8eab\u578b\u91cd\u75c7\u808c\u7121\u529b\uff08sn-gMG\uff09\uff1a2026\u5e741\u6708\uff0cFDA\u53d7\u7406\u4e86\u827e\u52a0\u83ab\u5fb7\u7528\u65bc\u6cbb\u7642\u6297\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6297\u9ad4(AChR-Ab)sn-gMG\u6210\u4eba\u60a3\u8005\u7684\u88dc\u5145\u751f\u7269\u88fd\u54c1\u8a31\u53ef\u7533\u8acb\uff08sBLA\uff09\u7684\u512a\u5148\u5be9\u8a55\uff0c\u8655\u65b9\u85e5\u7528\u6236\u4ed8\u8cbb\u6cd5\u6848\u76ee\u6a19\u884c\u52d5\u65e5\u671f\uff08PDFUA\uff09\u70ba2026\u5e745\u670810\u65e5\u3002\u518d\u9f0e\u91ab\u85e5\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u4e86ADAPT SERON 3\u671f\u7814\u7a76\u3002 KarXT\uff08\u546b\u8afe\u7f8e\u6797\u66f2\u53f8\u6c2f\u92a8\uff0cM1\/M4\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291\uff09\uff1a2025\u5e7412\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u6279\u51c6KarXT\u7528\u65bc\u6cbb\u7642\u6210\u4eba\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u3002KarXT\u662f70\u591a\u5e74\u4f86\u9996\u500b\u7372\u6279\u7684\u5177\u6709\u5275\u65b0\u4f5c\u7528\u6a5f\u5236\u7684\u7cbe\u795e\u5206\u88c2\u75c7\u7642\u6cd5\uff0c\u5e36\u4f86\u4e86\u5168\u65b0\u7684\u6cbb\u7642\u7bc4\u5f0f\u3002\u7522\u54c1\u8a08\u5283\u65bc2026\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u5728\u4e2d\u570b\u5546\u696d\u5316\u4e0a\u5e02\u3002 Povetacicept (APRIL\/BAFF)\uff1a2025\u5e7412\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u52a0\u5165\u4e86\u7528\u65bc\u6cbb\u7642\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u7684\u5168\u7403\u95dc\u9375\u60272\/3\u671fOLYMPUS\u7814\u7a76\uff0c\u4e26\u5728\u4e2d\u570b\u5167\u5730\u5b8c\u6210\u4e86\u9996\u4f8b\u60a3\u8005\u7d66\u85e5\u3002FDA\u6388\u4e88\u8a72\u7522\u54c1\u7528\u65bc\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u5feb\u901f\u901a\u9053\u548c\u5b64\u5152\u85e5\u8cc7\u683c\u8a8d\u5b9a\u3002EMA\u5df2\u6388\u4e88\u5176\u512a\u5148\u85e5\u54c1\uff08PRIME\uff09\u8cc7\u683c\u8a8d\u5b9a\u3002 Elegrobart (\u80f0\u5cf6\u7d20\u6a23\u751f\u9577\u56e0\u5b501\u53d7\u9ad4\u6291\u5236\u5291, 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