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Chen\u535a\u58eb\u88dc\u5145\u9053\uff1a\u300c\u6b64\u9805\u65b0\u85e5\u7533\u8acb\u5728\u7372\u5f97\u95dc\u9375\u6027\u4e09\u671f\u8a3b\u518a\u7814\u7a76ENHANCE-CHINA\u7684\u7a4d\u6975\u7d50\u679c\u5f8c\u5df2\u6309\u8a08\u5283\u5b8c\u6210\u63d0\u4ea4\u3002\u7e7c\u7a4d\u6975\u63a8\u52d5\u4e2d\u570b\u6fb3\u9580\u7372\u6279\uff0c\u53ca\u6d77\u5357\u535a\u9c32\u548c\u5927\u7063\u5340\u7684\u5148\u884c\u5148\u8a66\u9805\u76ee\u5f8c\uff0c\u6211\u5011\u671f\u5f85\u52a0\u901f\u63a8\u9032\u9019\u4e00\u5275\u65b0\u7642\u6cd5\u60e0\u53ca\u66f4\u5ee3\u6cdb\u7684\u4e2d\u570b\u60a3\u8005\u3002\u300d 2025\u5e742\u6708\uff0c\u6069\u53f8\u82ac\u7fa4\uff08Ohtuvayre\u00ae\uff09\u7372\u6fb3\u9580\u7279\u5225\u884c\u653f\u5340\u85e5\u7269\u76e3\u7763\u7ba1\u7406\u5c40\u6279\u51c6\uff0c\u4e26\u65bc2025\u5e7411\u6708\u901a\u904e\u300c\u6e2f\u6fb3\u85e5\u68b0\u901a\u300d\u653f\u7b56\u843d\u5730\u5927\u7063\u5340\uff0c\u53ef\u5728\u6307\u5b9a\u91ab\u7642\u6a5f\u69cb\u4f7f\u7528\u3002\u6b64\u5916\uff0c\u6069\u53f8\u82ac\u7fa4\uff08Ohtuvayre\u00ae\uff09\u5df2\u65bc2024\u5e7411\u6708\u5728\u6d77\u5357\u535a\u9c32\u6a02\u57ce\u5148\u884c\u5148\u8a66\u5340\u843d\u5730\u4f7f\u7528\u3002 2021\u5e74\uff0c\u512a\u92b3\u91ab\u85e5\u8207Verona Pharma\u7c3d\u7f72\u5354\u8b70\uff0cVerona Pharma\u6388\u4e88\u512a\u92b3\u91ab\u85e5\u5728\u5927\u4e2d\u83ef\u5340\uff08\u4e2d\u570b\u5927\u9678\u3001\u9999\u6e2f\u3001\u6fb3\u9580\u548c\u53f0\u7063\uff09\u81e8\u5e8a\u958b\u767c\u53ca\u5546\u696d\u5316\u6069\u53f8\u82ac\u7fa4\uff08Ohtuvayre\u00ae\uff09\u7684\u7368\u5bb6\u6b0a\u5229\u3002 2025\u5e7410\u6708\uff0c\u9ed8\u514b\u516c\u53f8\uff08Merck &amp; Co., Inc., Rahway, N.J., USA\uff0c\u5728\u7f8e\u570b\u548c\u52a0\u62ff\u5927\u4ee5\u5916\u7684\u5730\u5340\u7a31\u70baMSD\uff09\u5ba3\u4f48\u5df2\u5b8c\u6210\u5c0dVerona Pharma plc\u7684\u6536\u8cfc\u3002 \u95dc\u65bc\u6069\u53f8\u82ac\u7fa4\uff08Ensifentrine\uff0cOhtuvayre\u00ae\uff09\u6069\u53f8\u82ac\u7fa4\uff08Ensifentrine\uff0cOhtuvayre\u00ae\uff09\u662f\u9996\u6b3e\u7528\u65bc\u6210\u4eba\u7dad\u6301\u6cbb\u7642\u6162\u963b\u80ba\u7684\u5438\u5165\u7642\u6cd5\uff0c\u96d9\u91cd\u6291\u5236\u6a5f\u7406\u4f7f\u5176\u80fd\u5920\u6191\u501f\u55ae\u500b\u5316\u5408\u7269\u540c\u6642\u5be6\u73fe\u652f\u6c23\u7ba1\u64f4\u5f35\u548c\u6297\u708e\u6548\u61c9\u3002Verona Pharma\u901a\u904e\u4e09\u671f\u81e8\u5e8a\u9805\u76eeENHANCE\uff08\u300cEnsifentrine as a Novel inHAled Nebulized COPD 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Chen\u535a\u58eb\u88dc\u5145\u9053\uff1a\u300c\u6b64\u9805\u65b0\u85e5\u7533\u8acb\u5728\u7372\u5f97\u95dc\u9375\u6027\u4e09\u671f\u8a3b\u518a\u7814\u7a76ENHANCE-CHINA\u7684\u7a4d\u6975\u7d50\u679c\u5f8c\u5df2\u6309\u8a08\u5283\u5b8c\u6210\u63d0\u4ea4\u3002\u7e7c\u7a4d\u6975\u63a8\u52d5\u4e2d\u570b\u6fb3\u9580\u7372\u6279\uff0c\u53ca\u6d77\u5357\u535a\u9c32\u548c\u5927\u7063\u5340\u7684\u5148\u884c\u5148\u8a66\u9805\u76ee\u5f8c\uff0c\u6211\u5011\u671f\u5f85\u52a0\u901f\u63a8\u9032\u9019\u4e00\u5275\u65b0\u7642\u6cd5\u60e0\u53ca\u66f4\u5ee3\u6cdb\u7684\u4e2d\u570b\u60a3\u8005\u3002\u300d 2025\u5e742\u6708\uff0c\u6069\u53f8\u82ac\u7fa4\uff08Ohtuvayre\u00ae\uff09\u7372\u6fb3\u9580\u7279\u5225\u884c\u653f\u5340\u85e5\u7269\u76e3\u7763\u7ba1\u7406\u5c40\u6279\u51c6\uff0c\u4e26\u65bc2025\u5e7411\u6708\u901a\u904e\u300c\u6e2f\u6fb3\u85e5\u68b0\u901a\u300d\u653f\u7b56\u843d\u5730\u5927\u7063\u5340\uff0c\u53ef\u5728\u6307\u5b9a\u91ab\u7642\u6a5f\u69cb\u4f7f\u7528\u3002\u6b64\u5916\uff0c\u6069\u53f8\u82ac\u7fa4\uff08Ohtuvayre\u00ae\uff09\u5df2\u65bc2024\u5e7411\u6708\u5728\u6d77\u5357\u535a\u9c32\u6a02\u57ce\u5148\u884c\u5148\u8a66\u5340\u843d\u5730\u4f7f\u7528\u3002 2021\u5e74\uff0c\u512a\u92b3\u91ab\u85e5\u8207Verona Pharma\u7c3d\u7f72\u5354\u8b70\uff0cVerona Pharma\u6388\u4e88\u512a\u92b3\u91ab\u85e5\u5728\u5927\u4e2d\u83ef\u5340\uff08\u4e2d\u570b\u5927\u9678\u3001\u9999\u6e2f\u3001\u6fb3\u9580\u548c\u53f0\u7063\uff09\u81e8\u5e8a\u958b\u767c\u53ca\u5546\u696d\u5316\u6069\u53f8\u82ac\u7fa4\uff08Ohtuvayre\u00ae\uff09\u7684\u7368\u5bb6\u6b0a\u5229\u3002 2025\u5e7410\u6708\uff0c\u9ed8\u514b\u516c\u53f8\uff08Merck &amp; Co., Inc., Rahway, N.J., USA\uff0c\u5728\u7f8e\u570b\u548c\u52a0\u62ff\u5927\u4ee5\u5916\u7684\u5730\u5340\u7a31\u70baMSD\uff09\u5ba3\u4f48\u5df2\u5b8c\u6210\u5c0dVerona Pharma plc\u7684\u6536\u8cfc\u3002 \u95dc\u65bc\u6069\u53f8\u82ac\u7fa4\uff08Ensifentrine\uff0cOhtuvayre\u00ae\uff09\u6069\u53f8\u82ac\u7fa4\uff08Ensifentrine\uff0cOhtuvayre\u00ae\uff09\u662f\u9996\u6b3e\u7528\u65bc\u6210\u4eba\u7dad\u6301\u6cbb\u7642\u6162\u963b\u80ba\u7684\u5438\u5165\u7642\u6cd5\uff0c\u96d9\u91cd\u6291\u5236\u6a5f\u7406\u4f7f\u5176\u80fd\u5920\u6191\u501f\u55ae\u500b\u5316\u5408\u7269\u540c\u6642\u5be6\u73fe\u652f\u6c23\u7ba1\u64f4\u5f35\u548c\u6297\u708e\u6548\u61c9\u3002Verona Pharma\u901a\u904e\u4e09\u671f\u81e8\u5e8a\u9805\u76eeENHANCE\uff08\u300cEnsifentrine as a Novel inHAled Nebulized COPD thErapy\u300d\uff09\u8a55\u4f30\u4e86\u5438\u5165\u578b\u6069\u53f8\u82ac\u7fa4\uff08Ensifentrine\uff0cOhtuvayre\u00ae\uff09\u7528\u65bcCOPD\u7dad\u6301\u6cbb\u7642\u7684\u6548\u679c\u3002\u6069\u53f8\u82ac\u7fa4\uff08Ensifentrine\uff0cOhtuvayre\u00ae\uff09\u5728ENHANCE-1\u548cENHANCE-2\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u4e2d\u5747\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff0c\u986f\u793a\u51fa\u5177\u6709\u7d71\u8a08\u5b78\u610f\u7fa9\u548c\u81e8\u5e8a\u610f\u7fa9\u7684\u80ba\u529f\u80fd\u6539\u5584\u3002 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