{"id":393067,"date":"2025-12-15T21:18:00","date_gmt":"2025-12-15T13:18:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=393067"},"modified":"2025-12-15T21:18:00","modified_gmt":"2025-12-15T13:18:00","slug":"dmx-200-action3%e4%b8%89%e6%9c%9f%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a9%97%e5%ae%8c%e6%88%90%e6%82%a3%e8%80%85%e6%8b%9b%e5%8b%9f","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=393067","title":{"rendered":"DMX-200 ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5b8c\u6210\u60a3\u8005\u62db\u52df"},"content":{"rendered":"<div>\n<ul type=\"disc\">\n<li>Dimerix\u7684ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5df2\u6210\u529f\u5b8c\u6210\u60a3\u8005\u62db\u52df<sup>[1]<\/sup>\uff0c\u76ee\u6a19\u7b2c286\u4f8b\u6210\u5e74\u60a3\u8005\u5168\u90e8\u5b8c\u6210\u5165\u7d44\u4e26\u63a5\u53d7\u7d66\u85e5<\/li>\n<li>ACTION3\u4e09\u671f\u8a66\u9a57\u65e8\u5728\u8a55\u4f30DMX-200\u806f\u5408\u6a19\u6e96\u964d\u58d3\u85e5\u7269\u6cbb\u7642FSGS\u60a3\u8005\u5169\u5e74\u671f\u9593\u7684\u7642\u6548\u8207\u5b89\u5168\u6027<\/li>\n<li>\u5728\u5b8c\u6210\u7d66\u85e5\u7684286\u4f8b\u6210\u5e74\u60a3\u8005\u4e2d\uff0c\u5df2\u670969\u4f8b\u5b8c\u6210\u5b8c\u6574\u7684\u5169\u5e74\u6cbb\u7642\u671f\uff0c\u5176\u4e2d65\u4f8b\u81ea\u9858\u52a0\u5165\u958b\u653e\u6a19\u7c64\u64f4\u5c55\uff08<b>OLE<\/b>\uff09\u7814\u7a76\uff0cOLE\u53c3\u8207\u7387\u905494%<\/li>\n<li>\u7814\u7a76\u5df2\u9806\u5229\u901a\u904e\u4e03\u6b21\u9810\u5b9a\u7684\u7368\u7acb\u6578\u64da\u76e3\u67e5\u59d4\u54e1\u6703\uff08IDMC\uff09\u5be9\u67e5\uff0c\u671f\u9593\u672a\u767c\u73fe\u9700\u4fee\u6539\u8a66\u9a57\u65b9\u6848\u6216\u5b58\u5728\u5b89\u5168\u6027\u554f\u984c\u7684\u60c5\u6cc1<sup>[2]<\/sup><\/li>\n<li>\u57fa\u65bcPARASOL\u5408\u4f5c\u6578\u64da\u5206\u6790\uff08<b>PARASOL\u7814\u7a76\u7d50\u679c<\/b>\uff09\u53d6\u5f97\u7684\u7a4d\u6975\u6210\u679c\uff0cDimerix\u8207\u5176\u7f8e\u570b\u5408\u4f5c\u5925\u4f34Amicus Therapeutics\u8a08\u5283\u5728\u5c0dACTION3\u8a66\u9a57\u6578\u64da\u9032\u884c\u76f2\u614b\u5206\u6790\u524d\uff0c\u5c31\u64ec\u8b70\u7684\u81e8\u5e8a\u8a66\u9a57\u7d42\u9ede\u5411FDA\u5fb5\u8a62\u610f\u898b<sup>[3]<\/sup><\/li>\n<li>\u5152\u79d1\u60a3\u8005\u4f5c\u70ba\u7368\u7acb\u968a\u5217\u7684\u62db\u52df\u5de5\u4f5c\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u82e5\u53d6\u5f97\u6210\u529f\uff0c\u5c07\u4f7fDimerix\u6709\u6a5f\u6703\u5728\u4e3b\u8981\u5e02\u5834\u5c07DMX-200\u7684\u9069\u7528\u4eba\u7fa4\u64f4\u5c55\u81f3\u9752\u5c11\u5e74\u60a3\u8005<\/li>\n<li>Dimerix\u7e7c\u7e8c\u4fdd\u6301\u5145\u88d5\u8cc7\u91d1\u5132\u5099\uff0c\u4ee5\u652f\u6301\u5305\u62ecACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5728\u5167\u7684\u904b\u71df\u9700\u6c42\uff0c\u540c\u6642\u6301\u7e8c\u8a55\u4f30\u65b0\u7684\u7814\u767c\u6a5f\u9047<\/li>\n<\/ul>\n<p id=\"temp_ReleaseStart\"><span class=\"legendSpanClass\">\u6fb3\u5927\u5229\u4e9e\u58a8\u723e\u672c<\/span><span class=\"legendSpanClass\">2025\u5e7412\u670815\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u64c1\u6709\u814e\u75c5\u9818\u57df\u4e09\u671f\u81e8\u5e8a\u8cc7\u7522\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8Dimerix Limited\uff08ASX: DXB\uff09\u4eca\u65e5\u5ba3\u4f48\uff0c\u5176\u91dd\u5c0d\u5c40\u7076\u7bc0\u6bb5\u6027\u814e\u5c0f\u7403\u786c\u5316\uff08FSGS\uff09\u60a3\u8005\u7684DMX-200\u85e5\u7269ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\uff0c\u5df2\u6210\u529f\u6309\u8a08\u5283\u5b8c\u6210\u7b2c286\u4f8b\u6210\u5e74\u60a3\u8005\u7684\u5165\u7d44\u8207\u7d66\u85e5<sup>[1]<\/sup>\u3002<\/p>\n<p class=\"prntal\">ACTION3\u4e09\u671f\u7814\u7a76\u662f\u4e00\u9805\u95dc\u9375\u6027\u3001\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u7684\u81e8\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u8a55\u4f30DMX-200\u5c0d\u6b63\u5728\u63a5\u53d7\u7a69\u5b9a\u5291\u91cf\u8840\u7ba1\u7dca\u5f35\u7d20\u2161\u53d7\u9ad4\u62ee\u6297\u5291\uff08ARB\uff09\u6cbb\u7642\u7684FSGS\u60a3\u8005\u7684\u7642\u6548\u8207\u5b89\u5168\u6027\u3002\u60a3\u8005\u5728\u4f7f\u7528\u7a69\u5b9a\u5291\u91cf\u7684ARB\u5f8c\uff0c\u5c07\u88ab\u96a8\u6a5f\u5206\u914d\u81f3DMX-200\u7d44\uff08120\u6beb\u514b\u81a0\u56ca\uff0c\u6bcf\u65e5\u5169\u6b21\uff09\u6216\u5b89\u6170\u5291\u7d44\uff0c\u9032\u884c\u70ba\u671f\u5169\u5e74\u7684\u6cbb\u7642\u3002\u8a72\u9805\u91dd\u5c0dFSGS\u60a3\u8005\u7684\u55ae\u4e00\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\uff0c\u65e8\u5728\u901a\u904e\u6536\u96c6\u6cbb\u7642\u671f\u9593\u86cb\u767d\u5c3f\u6e1b\u5c11\u53ca\u814e\u529f\u80fd\uff08\u4f30\u7b97\u814e\u5c0f\u7403\u6ffe\u904e\u7387\u659c\u7387\uff09\u6539\u5584\u7684\u8b49\u64da\uff0c\u70ba\u85e5\u54c1\u7372\u5f97\u4e0a\u5e02\u6279\u51c6\u63d0\u4f9b\u5145\u5206\u4f9d\u64da\u3002<\/p>\n<p class=\"prntal\">\u6839\u64da\u8a66\u9a57\u65b9\u6848\uff0c\u60a3\u8005\u5b8c\u6210\u521d\u6b65\u5165\u7d44\u5f8c\u9700\u5728\u80cc\u666f\u7528\u85e5\u4e0b\u9032\u5165\u7a69\u5b9a\u671f\uff0c\u96a8\u5f8c\u63a5\u53d7\u4e8c\u6b21\u7be9\u9078\u3002\u50c5\u901a\u904e\u518d\u6b21\u7be9\u9078\u7684\u60a3\u8005\u65b9\u53ef\u88ab\u96a8\u6a5f\u5206\u914d\u81f3DMX-200\u7d44\u6216\u5b89\u6170\u5291\u7d44\u3002\u4f9d\u7167\u6a19\u6e96\u6d41\u7a0b\uff0c\u7576\u524d\u5df2\u5b8c\u6210\u5165\u7d44\u4e26\u8655\u65bc\u7a69\u5b9a\u671f\u7684\u60a3\u8005\u82e5\u4ecd\u7b26\u5408\u689d\u4ef6\uff0c\u5c07\u7e7c\u7e8c\u53c3\u8207\u7814\u7a76\uff1b\u5f85\u5176\u5b8c\u6210\u7d66\u85e5\u5f8c\uff0c\u6700\u7d42\u60a3\u8005\u5165\u7d44\u53ca\u672b\u6b21\u7d66\u85e5\u65e5\u671f\u65b9\u80fd\u6b63\u5f0f\u78ba\u5b9a\u3002<\/p>\n<p class=\"prntal\">\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0cDimerix\u66fe\u65bc2024\u5e743\u6708\u5ba3\u4f48\uff0c\u91dd\u5c0dFSGS\u60a3\u8005\u7684DMX-200\u85e5\u7269ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\uff0c\u5728\u91dd\u5c0d\u524d72\u540d\u96a8\u6a5f\u60a3\u8005\u7684\u86cb\u767d\u5c3f\uff08\u7642\u6548\uff09\u7d42\u9ede\u9810\u8a2d\u4e2d\u671f\u5206\u6790\u4e2d\u53d6\u5f97\u7a4d\u6975\u7d50\u679c\u3002<sup>[4]\u00a0<\/sup>\u8a72\u5206\u6790\u986f\u793a\uff0c\u6839\u64da\u7d71\u8a08\u5b78\u6e2c\u91cf\uff0c\u5728\u7576\u6642\u6642\u9593\u7bc0\u9ede\uff0cDMX-200\u5728\u964d\u4f4eFSGS\u60a3\u8005\u86cb\u767d\u5c3f\uff08\u814e\u75c5\u9032\u5c55\u7684\u66ff\u4ee3\u6a19\u8a8c\u7269<sup>[5]<\/sup>\uff09\u65b9\u9762\u8868\u73fe\u512a\u65bc\u5b89\u6170\u5291\u7d44\u3002<sup>[6]<\/sup><\/p>\n<p class=\"prntal\"><i>Dimerix\u9996\u5e2d\u57f7\u884c\u5b98\u517c\u8463\u4e8b\u7e3d\u7d93\u7406Nina Webster\u535a\u58eb<\/i>\u8868\u793a\uff1a\u300c\u6211\u5011\u5f88\u9ad8\u8208\u5ba3\u4f48\uff0cACTION3\u4e09\u671f\u8a66\u9a57\u4e2d\u7b2c286\u4f4d\u60a3\u8005\u7684\u5165\u7d44\u3001\u96a8\u6a5f\u5206\u7d44\u53ca\u7d66\u85e5\u5de5\u4f5c\u5df2\u5713\u6eff\u5b8c\u6210\uff0c\u9019\u9ad4\u73fe\u4e86Dimerix\u5718\u968a\u53ca\u81e8\u5e8a\u5408\u4f5c\u5925\u4f34\u7684\u5c08\u696d\u627f\u8afe\u8207\u5353\u8d8a\u57f7\u884c\u529b\u3002\u5728\u7f55\u898b\u75c5\u7814\u7a76\u9818\u57df\u9054\u6210\u9019\u4e00\u91cc\u7a0b\u7891\uff0c\u5f70\u986f\u4e86\u6211\u5011\u5728\u8907\u96dc\u74b0\u5883\u4e2d\u9ad8\u6548\u63a8\u9032\u7684\u80fd\u529b\u3002\u96a8\u8457\u5169\u5e74\u6cbb\u7642\u671f\u5167\u60a3\u8005\u6578\u64da\u7684\u6301\u7e8c\u7a4d\u7d2f\uff0c\u6211\u5011\u6b63\u9010\u6b65\u9081\u5411\u591a\u500b\u95dc\u9375\u50f9\u503c\u8f49\u6298\u9ede\u3002\u672c\u6b21\u7814\u7a76\u6210\u529f\u9054\u6210\u62db\u52df\u76ee\u6a19\uff0c\u70baDimerix\u8207\u5546\u696d\u5408\u4f5c\u5925\u4f34\u6301\u7e8c\u63a8\u9032\u76e3\u7ba1\u7533\u5831\u548c\u6f5b\u5728\u5546\u696d\u5316\u9032\u7a0b\u5960\u5b9a\u57fa\u790e\u3002\u6211\u5011\u8877\u5fc3\u611f\u8b1d\u6240\u6709\u60a3\u8005\u53ca\u5176\u5bb6\u5c6c\u70ba\u6b64\u91cd\u8981\u7814\u7a76\u9805\u76ee\u505a\u51fa\u7684\u5bf6\u8cb4\u8ca2\u737b\u3002\u300d<\/p>\n<p class=\"prntal\">ACTION3\u8a66\u9a57\u5728\u5168\u740321\u500b\u570b\u5bb6\u548c\u5730\u5340\u958b\u8a2d\u4e86219\u500b\u62db\u52df\u4e2d\u5fc3\uff0c\u8986\u84cb\u7f8e\u570b\u3001\u6b50\u6d32\u3001\u82f1\u570b\u3001\u65e5\u672c\u3001\u4e2d\u570b\u5927\u9678\u3001\u9999\u6e2f\u3001\u53f0\u7063\u3001\u99ac\u4f86\u897f\u4e9e\u3001\u6fb3\u5927\u5229\u4e9e\u53ca\u65b0\u897f\u862d\u7b49\u5730\u3002<\/p>\n<p class=\"prntal\"><b>\u7f8e\u570b\u5730\u5340\u5f8c\u7e8c\u8a08\u5283<\/b><\/p>\n<p class=\"prntal\">Dimerix\u8207\u5176\u7f8e\u570b\u5408\u4f5c\u5925\u4f34Amicus Therapeutics\u8a08\u5283\u5c31104\u5468\u8a66\u9a57\u7d42\u9ede\u6307\u6a19\uff0c\u5411\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5fb5\u8a62\u610f\u898b\uff0c\u4e26\u53ef\u80fd\u57fa\u65bc\u6b64\u63d0\u4ea4\u52a0\u901f\u5be9\u6279\u7533\u8acb\u3002<\/p>\n<p class=\"prntal\"><b>\u95dc\u65bc<\/b><b>ACTION3 FSGS\u4e09\u671f\u7814\u7a76<\/b><\/p>\n<p class=\"prntal\">\u9019\u9805\u7814\u7a76\u540d\u70ba\u300c\u8840\u7ba1\u7dca\u5f35\u7d20II\u20111\u578b\u53d7\u9ad4\uff08AT1R\uff09\u8207\u8da8\u5316\u56e0\u5b50\u53d7\u9ad42\uff08CCR2\uff09\u9776\u5411\u6cbb\u7642\u708e\u75c7\u6027\u814e\u75c5\u7684III\u671f\u81e8\u5e8a\u8a66\u9a57\u300d\uff08\u7c21\u7a31ACTION3\uff09\uff0c\u662f\u4e00\u9805\u95dc\u9375\u6027\uff08\u4e09\u671f\uff09\u3001\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u81e8\u5e8a\u8a66\u9a57\uff0c\u65e8\u5728\u8a55\u4f30DMX-200\u5c0d\u6b63\u5728\u63a5\u53d7\u7a69\u5b9a\u5291\u91cf\u8840\u7ba1\u7dca\u5f35\u7d20\u2161\u53d7\u9ad4\u62ee\u6297\u5291\uff08ARB\uff09\u6cbb\u7642\u7684FSGS\u60a3\u8005\u7684\u7642\u6548\u8207\u5b89\u5168\u6027\u3002<\/p>\n<p class=\"prntal\">\u66f4\u591a\u7814\u7a76\u76f8\u95dc\u4fe1\u606f\u53ef\u901a\u904eClinicalTrials.gov\uff08\u8a66\u9a57\u7de8\u865f\uff1aNCT05183646\uff09\u6216\u6fb3\u5927\u5229\u4e9e-\u65b0\u897f\u862d\u81e8\u5e8a\u8a66\u9a57\u8a3b\u518a\u4e2d\u5fc3\uff08ANZCTR\uff09\uff08\u8a66\u9a57\u7de8\u865f\uff1aACTRN12622000066785\uff09\u67e5\u8a62\u3002<\/p>\n<p class=\"prntal\"><b>\u53c3\u8003<\/b><\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><i><span class=\"prnews_span\"><sup>[1]<\/sup><\/span><\/i>\u00a0<i>\u6700\u7d42\u7d71\u8a08\u529f\u6548\u9700\u5f852025\u5e74\u7b2c\u56db\u5b63\u5ea6\u5b8c\u6210\u7684\u76f2\u614b\u5206\u6790\u78ba\u8a8d\u3002<\/i><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><i><span class=\"prnews_span\"><sup>[2]<\/sup><\/span><\/i>\u00a0<i>\u6fb3\u5927\u5229\u4e9e\u8b49\u5238\u4ea4\u6613\u6240\u516c\u544a\uff0c\u767c\u4f48\u65bc2025\u5e7411\u670819\u65e5<\/i><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><i><span class=\"prnews_span\"><sup>[3]<\/sup><\/span><\/i>\u00a0<i>\u6fb3\u5927\u5229\u4e9e\u8b49\u5238\u4ea4\u6613\u6240\u516c\u544a\uff0c\u767c\u4f48\u65bc2025\u5e7410\u67088\u65e5<\/i><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><i><span class=\"prnews_span\"><sup>[4]<\/sup><\/span><\/i>\u00a0<i>\u6fb3\u5927\u5229\u4e9e\u8b49\u5238\u4ea4\u6613\u6240\u516c\u544a\uff0c\u767c\u4f48\u65bc2024\u5e743\u670811\u65e5<\/i><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><i><span class=\"prnews_span\"><sup>[5]<\/sup><\/span><\/i>\u00a0 <i>Haider M\u3001Aslam A\uff082023\u5e74\uff09\uff0c\u300a\u86cb\u767d\u5c3f\u300b\uff1bPMID: 33232060\uff0c\u5728\u7dda\u67e5\u95b1\uff1a<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33232060\/\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow\" style=\"color: #0000FF\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33232060\/<\/a><\/i><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\"><i><span class=\"prnews_span\"><sup>[6]<\/sup><\/span><\/i>\u00a0<i>\u4e2d\u671f\u5206\u6790\u7d50\u679c\u4e0d\u80fd\u4fdd\u8b49\u8a66\u9a57\u6700\u7d42\u7d50\u679c\u5177\u6709\u7d71\u8a08\u986f\u8457\u6027<\/i><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p class=\"prntal\">\u00a0<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Dimerix\u7684ACTION3&#8230;<\/p>\n","protected":false},"author":16,"featured_media":199219,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-393067","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>DMX-200 ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5b8c\u6210\u60a3\u8005\u62db\u52df - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831<\/title>\n<meta name=\"description\" content=\"Dimerix\u7684ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5df2\u6210\u529f\u5b8c\u6210\u60a3\u8005\u62db\u52df\uff0c\u76ee\u6a19\u7b2c286\u4f8b\u6210\u5e74\u60a3\u8005\u5168\u90e8\u5b8c\u6210\u5165\u7d44\u4e26\u63a5\u53d7\u7d66\u85e5  ACTION3\u4e09\u671f\u8a66\u9a57\u65e8\u5728\u8a55\u4f30DMX-200\u806f\u5408\u6a19\u6e96\u964d\u58d3\u85e5\u7269\u6cbb\u7642FSGS\u60a3\u8005\u5169\u5e74\u671f\u9593\u7684\u7642\u6548\u8207\u5b89\u5168\u6027  \u5728\u5b8c\u6210\u7d66\u85e5\u7684286\u4f8b\u6210\u5e74\u60a3\u8005\u4e2d\uff0c\u5df2\u670969\u4f8b\u5b8c\u6210\u5b8c\u6574\u7684\u5169\u5e74\u6cbb\u7642\u671f\uff0c\u5176\u4e2d65\u4f8b\u81ea\u9858\u52a0\u5165\u958b\u653e\u6a19\u7c64\u64f4\u5c55\uff08OLE\uff09\u7814\u7a76\uff0cOLE\u53c3\u8207\u7387\u905494%  \u7814\u7a76\u5df2\u9806\u5229\u901a\u904e\u4e03\u6b21\u9810\u5b9a\u7684\u7368\u7acb\u6578\u64da\u76e3\u67e5\u59d4\u54e1\u6703\uff08IDMC\uff09\u5be9\u67e5\uff0c\u671f\u9593\u672a\u767c\u73fe\u9700\u4fee\u6539\u8a66\u9a57\u65b9\u6848\u6216\u5b58\u5728\u5b89\u5168\u6027\u554f\u984c\u7684\u60c5\u6cc1  \u57fa\u65bcPARASOL\u5408\u4f5c\u6578\u64da\u5206\u6790\uff08PARASOL\u7814\u7a76\u7d50\u679c\uff09\u53d6\u5f97\u7684\u7a4d\u6975\u6210\u679c\uff0cDimerix\u8207\u5176\u7f8e\u570b\u5408\u4f5c\u5925\u4f34Amicus Therapeutics\u8a08\u5283\u5728\u5c0dACTION3\u8a66\u9a57\u6578\u64da\u9032\u884c\u76f2\u614b\u5206\u6790\u524d\uff0c\u5c31\u64ec\u8b70\u7684\u81e8\u5e8a\u8a66\u9a57\u7d42\u9ede\u5411FDA\u5fb5\u8a62\u610f\u898b  \u5152\u79d1\u60a3\u8005\u4f5c\u70ba\u7368\u7acb\u968a\u5217\u7684\u62db\u52df\u5de5\u4f5c\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u82e5\u53d6\u5f97\u6210\u529f\uff0c\u5c07\u4f7fDimerix\u6709\u6a5f\u6703\u5728\u4e3b\u8981\u5e02\u5834\u5c07DMX-200\u7684\u9069\u7528\u4eba\u7fa4\u64f4\u5c55\u81f3\u9752\u5c11\u5e74\u60a3\u8005  Dimerix\u7e7c\u7e8c\u4fdd\u6301\u5145\u88d5\u8cc7\u91d1\u5132\u5099\uff0c\u4ee5\u652f\u6301\u5305\u62ecACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5728\u5167\u7684\u904b\u71df\u9700\u6c42\uff0c\u540c\u6642\u6301\u7e8c\u8a55\u4f30\u65b0\u7684\u7814\u767c\u6a5f\u9047  \u6fb3\u5927\u5229\u4e9e\u58a8\u723e\u672c2025\u5e7412\u670815\u65e5 \/\u7f8e\u901a\u793e\/ -- \u64c1\u6709\u814e\u75c5\u9818\u57df\u4e09\u671f\u81e8\u5e8a\u8cc7\u7522\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8Dimerix Limited\uff08ASX: 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Webster\u535a\u58eb\u8868\u793a\uff1a\u300c\u6211\u5011\u5f88\u9ad8\u8208\u5ba3\u4f48\uff0cACTION3\u4e09\u671f\u8a66\u9a57\u4e2d\u7b2c286\u4f4d\u60a3\u8005\u7684\u5165\u7d44\u3001\u96a8\u6a5f\u5206\u7d44\u53ca\u7d66\u85e5\u5de5\u4f5c\u5df2\u5713\u6eff\u5b8c\u6210\uff0c\u9019\u9ad4\u73fe\u4e86Dimerix\u5718\u968a\u53ca\u81e8\u5e8a\u5408\u4f5c\u5925\u4f34\u7684\u5c08\u696d\u627f\u8afe\u8207\u5353\u8d8a\u57f7\u884c\u529b\u3002\u5728\u7f55\u898b\u75c5\u7814\u7a76\u9818\u57df\u9054\u6210\u9019\u4e00\u91cc\u7a0b\u7891\uff0c\u5f70\u986f\u4e86\u6211\u5011\u5728\u8907\u96dc\u74b0\u5883\u4e2d\u9ad8\u6548\u63a8\u9032\u7684\u80fd\u529b\u3002\u96a8\u8457\u5169\u5e74\u6cbb\u7642\u671f\u5167\u60a3\u8005\u6578\u64da\u7684\u6301\u7e8c\u7a4d\u7d2f\uff0c\u6211\u5011\u6b63\u9010\u6b65\u9081\u5411\u591a\u500b\u95dc\u9375\u50f9\u503c\u8f49\u6298\u9ede\u3002\u672c\u6b21\u7814\u7a76\u6210\u529f\u9054\u6210\u62db\u52df\u76ee\u6a19\uff0c\u70baDimerix\u8207\u5546\u696d\u5408\u4f5c\u5925\u4f34\u6301\u7e8c\u63a8\u9032\u76e3\u7ba1\u7533\u5831\u548c\u6f5b\u5728\u5546\u696d\u5316\u9032\u7a0b\u5960\u5b9a\u57fa\u790e\u3002\u6211\u5011\u8877\u5fc3\u611f\u8b1d\u6240\u6709\u60a3\u8005\u53ca\u5176\u5bb6\u5c6c\u70ba\u6b64\u91cd\u8981\u7814\u7a76\u9805\u76ee\u505a\u51fa\u7684\u5bf6\u8cb4\u8ca2\u737b\u3002\u300d ACTION3\u8a66\u9a57\u5728\u5168\u740321\u500b\u570b\u5bb6\u548c\u5730\u5340\u958b\u8a2d\u4e86219\u500b\u62db\u52df\u4e2d\u5fc3\uff0c\u8986\u84cb\u7f8e\u570b\u3001\u6b50\u6d32\u3001\u82f1\u570b\u3001\u65e5\u672c\u3001\u4e2d\u570b\u5927\u9678\u3001\u9999\u6e2f\u3001\u53f0\u7063\u3001\u99ac\u4f86\u897f\u4e9e\u3001\u6fb3\u5927\u5229\u4e9e\u53ca\u65b0\u897f\u862d\u7b49\u5730\u3002 \u7f8e\u570b\u5730\u5340\u5f8c\u7e8c\u8a08\u5283 Dimerix\u8207\u5176\u7f8e\u570b\u5408\u4f5c\u5925\u4f34Amicus Therapeutics\u8a08\u5283\u5c31104\u5468\u8a66\u9a57\u7d42\u9ede\u6307\u6a19\uff0c\u5411\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5fb5\u8a62\u610f\u898b\uff0c\u4e26\u53ef\u80fd\u57fa\u65bc\u6b64\u63d0\u4ea4\u52a0\u901f\u5be9\u6279\u7533\u8acb\u3002 \u95dc\u65bcACTION3 FSGS\u4e09\u671f\u7814\u7a76 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\u66f4\u591a\u7814\u7a76\u76f8\u95dc\u4fe1\u606f\u53ef\u901a\u904eClinicalTrials.gov\uff08\u8a66\u9a57\u7de8\u865f\uff1aNCT05183646\uff09\u6216\u6fb3\u5927\u5229\u4e9e-\u65b0\u897f\u862d\u81e8\u5e8a\u8a66\u9a57\u8a3b\u518a\u4e2d\u5fc3\uff08ANZCTR\uff09\uff08\u8a66\u9a57\u7de8\u865f\uff1aACTRN12622000066785\uff09\u67e5\u8a62\u3002 \u53c3\u8003          \u00a0\u6700\u7d42\u7d71\u8a08\u529f\u6548\u9700\u5f852025\u5e74\u7b2c\u56db\u5b63\u5ea6\u5b8c\u6210\u7684\u76f2\u614b\u5206\u6790\u78ba\u8a8d\u3002         \u00a0\u6fb3\u5927\u5229\u4e9e\u8b49\u5238\u4ea4\u6613\u6240\u516c\u544a\uff0c\u767c\u4f48\u65bc2025\u5e7411\u670819\u65e5         \u00a0\u6fb3\u5927\u5229\u4e9e\u8b49\u5238\u4ea4\u6613\u6240\u516c\u544a\uff0c\u767c\u4f48\u65bc2025\u5e7410\u67088\u65e5         \u00a0\u6fb3\u5927\u5229\u4e9e\u8b49\u5238\u4ea4\u6613\u6240\u516c\u544a\uff0c\u767c\u4f48\u65bc2024\u5e743\u670811\u65e5         \u00a0 Haider M\u3001Aslam A\uff082023\u5e74\uff09\uff0c\u300a\u86cb\u767d\u5c3f\u300b\uff1bPMID: 33232060\uff0c\u5728\u7dda\u67e5\u95b1\uff1ahttps:\/\/pubmed.ncbi.nlm.nih.gov\/33232060\/         \u00a0\u4e2d\u671f\u5206\u6790\u7d50\u679c\u4e0d\u80fd\u4fdd\u8b49\u8a66\u9a57\u6700\u7d42\u7d50\u679c\u5177\u6709\u7d71\u8a08\u986f\u8457\u6027         \u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=393067\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"DMX-200 ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5b8c\u6210\u60a3\u8005\u62db\u52df - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"Dimerix\u7684ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5df2\u6210\u529f\u5b8c\u6210\u60a3\u8005\u62db\u52df\uff0c\u76ee\u6a19\u7b2c286\u4f8b\u6210\u5e74\u60a3\u8005\u5168\u90e8\u5b8c\u6210\u5165\u7d44\u4e26\u63a5\u53d7\u7d66\u85e5  ACTION3\u4e09\u671f\u8a66\u9a57\u65e8\u5728\u8a55\u4f30DMX-200\u806f\u5408\u6a19\u6e96\u964d\u58d3\u85e5\u7269\u6cbb\u7642FSGS\u60a3\u8005\u5169\u5e74\u671f\u9593\u7684\u7642\u6548\u8207\u5b89\u5168\u6027  \u5728\u5b8c\u6210\u7d66\u85e5\u7684286\u4f8b\u6210\u5e74\u60a3\u8005\u4e2d\uff0c\u5df2\u670969\u4f8b\u5b8c\u6210\u5b8c\u6574\u7684\u5169\u5e74\u6cbb\u7642\u671f\uff0c\u5176\u4e2d65\u4f8b\u81ea\u9858\u52a0\u5165\u958b\u653e\u6a19\u7c64\u64f4\u5c55\uff08OLE\uff09\u7814\u7a76\uff0cOLE\u53c3\u8207\u7387\u905494%  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\u5152\u79d1\u60a3\u8005\u4f5c\u70ba\u7368\u7acb\u968a\u5217\u7684\u62db\u52df\u5de5\u4f5c\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u82e5\u53d6\u5f97\u6210\u529f\uff0c\u5c07\u4f7fDimerix\u6709\u6a5f\u6703\u5728\u4e3b\u8981\u5e02\u5834\u5c07DMX-200\u7684\u9069\u7528\u4eba\u7fa4\u64f4\u5c55\u81f3\u9752\u5c11\u5e74\u60a3\u8005  Dimerix\u7e7c\u7e8c\u4fdd\u6301\u5145\u88d5\u8cc7\u91d1\u5132\u5099\uff0c\u4ee5\u652f\u6301\u5305\u62ecACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u5728\u5167\u7684\u904b\u71df\u9700\u6c42\uff0c\u540c\u6642\u6301\u7e8c\u8a55\u4f30\u65b0\u7684\u7814\u767c\u6a5f\u9047  \u6fb3\u5927\u5229\u4e9e\u58a8\u723e\u672c2025\u5e7412\u670815\u65e5 \/\u7f8e\u901a\u793e\/ -- \u64c1\u6709\u814e\u75c5\u9818\u57df\u4e09\u671f\u81e8\u5e8a\u8cc7\u7522\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8Dimerix Limited\uff08ASX: DXB\uff09\u4eca\u65e5\u5ba3\u4f48\uff0c\u5176\u91dd\u5c0d\u5c40\u7076\u7bc0\u6bb5\u6027\u814e\u5c0f\u7403\u786c\u5316\uff08FSGS\uff09\u60a3\u8005\u7684DMX-200\u85e5\u7269ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\uff0c\u5df2\u6210\u529f\u6309\u8a08\u5283\u5b8c\u6210\u7b2c286\u4f8b\u6210\u5e74\u60a3\u8005\u7684\u5165\u7d44\u8207\u7d66\u85e5\u3002 ACTION3\u4e09\u671f\u7814\u7a76\u662f\u4e00\u9805\u95dc\u9375\u6027\u3001\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u7684\u81e8\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u8a55\u4f30DMX-200\u5c0d\u6b63\u5728\u63a5\u53d7\u7a69\u5b9a\u5291\u91cf\u8840\u7ba1\u7dca\u5f35\u7d20\u2161\u53d7\u9ad4\u62ee\u6297\u5291\uff08ARB\uff09\u6cbb\u7642\u7684FSGS\u60a3\u8005\u7684\u7642\u6548\u8207\u5b89\u5168\u6027\u3002\u60a3\u8005\u5728\u4f7f\u7528\u7a69\u5b9a\u5291\u91cf\u7684ARB\u5f8c\uff0c\u5c07\u88ab\u96a8\u6a5f\u5206\u914d\u81f3DMX-200\u7d44\uff08120\u6beb\u514b\u81a0\u56ca\uff0c\u6bcf\u65e5\u5169\u6b21\uff09\u6216\u5b89\u6170\u5291\u7d44\uff0c\u9032\u884c\u70ba\u671f\u5169\u5e74\u7684\u6cbb\u7642\u3002\u8a72\u9805\u91dd\u5c0dFSGS\u60a3\u8005\u7684\u55ae\u4e00\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\uff0c\u65e8\u5728\u901a\u904e\u6536\u96c6\u6cbb\u7642\u671f\u9593\u86cb\u767d\u5c3f\u6e1b\u5c11\u53ca\u814e\u529f\u80fd\uff08\u4f30\u7b97\u814e\u5c0f\u7403\u6ffe\u904e\u7387\u659c\u7387\uff09\u6539\u5584\u7684\u8b49\u64da\uff0c\u70ba\u85e5\u54c1\u7372\u5f97\u4e0a\u5e02\u6279\u51c6\u63d0\u4f9b\u5145\u5206\u4f9d\u64da\u3002 \u6839\u64da\u8a66\u9a57\u65b9\u6848\uff0c\u60a3\u8005\u5b8c\u6210\u521d\u6b65\u5165\u7d44\u5f8c\u9700\u5728\u80cc\u666f\u7528\u85e5\u4e0b\u9032\u5165\u7a69\u5b9a\u671f\uff0c\u96a8\u5f8c\u63a5\u53d7\u4e8c\u6b21\u7be9\u9078\u3002\u50c5\u901a\u904e\u518d\u6b21\u7be9\u9078\u7684\u60a3\u8005\u65b9\u53ef\u88ab\u96a8\u6a5f\u5206\u914d\u81f3DMX-200\u7d44\u6216\u5b89\u6170\u5291\u7d44\u3002\u4f9d\u7167\u6a19\u6e96\u6d41\u7a0b\uff0c\u7576\u524d\u5df2\u5b8c\u6210\u5165\u7d44\u4e26\u8655\u65bc\u7a69\u5b9a\u671f\u7684\u60a3\u8005\u82e5\u4ecd\u7b26\u5408\u689d\u4ef6\uff0c\u5c07\u7e7c\u7e8c\u53c3\u8207\u7814\u7a76\uff1b\u5f85\u5176\u5b8c\u6210\u7d66\u85e5\u5f8c\uff0c\u6700\u7d42\u60a3\u8005\u5165\u7d44\u53ca\u672b\u6b21\u7d66\u85e5\u65e5\u671f\u65b9\u80fd\u6b63\u5f0f\u78ba\u5b9a\u3002 \u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0cDimerix\u66fe\u65bc2024\u5e743\u6708\u5ba3\u4f48\uff0c\u91dd\u5c0dFSGS\u60a3\u8005\u7684DMX-200\u85e5\u7269ACTION3\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\uff0c\u5728\u91dd\u5c0d\u524d72\u540d\u96a8\u6a5f\u60a3\u8005\u7684\u86cb\u767d\u5c3f\uff08\u7642\u6548\uff09\u7d42\u9ede\u9810\u8a2d\u4e2d\u671f\u5206\u6790\u4e2d\u53d6\u5f97\u7a4d\u6975\u7d50\u679c\u3002\u00a0\u8a72\u5206\u6790\u986f\u793a\uff0c\u6839\u64da\u7d71\u8a08\u5b78\u6e2c\u91cf\uff0c\u5728\u7576\u6642\u6642\u9593\u7bc0\u9ede\uff0cDMX-200\u5728\u964d\u4f4eFSGS\u60a3\u8005\u86cb\u767d\u5c3f\uff08\u814e\u75c5\u9032\u5c55\u7684\u66ff\u4ee3\u6a19\u8a8c\u7269\uff09\u65b9\u9762\u8868\u73fe\u512a\u65bc\u5b89\u6170\u5291\u7d44\u3002 Dimerix\u9996\u5e2d\u57f7\u884c\u5b98\u517c\u8463\u4e8b\u7e3d\u7d93\u7406Nina 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