{"id":391581,"date":"2025-12-11T13:50:00","date_gmt":"2025-12-11T05:50:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=391581"},"modified":"2025-12-11T13:50:00","modified_gmt":"2025-12-11T05:50:00","slug":"%e6%96%b0%e6%a9%8b%e7%94%9f%e7%89%a9%e5%85%ac%e4%bd%88-ragistomig-1%e6%9c%9f%e5%8a%91%e9%87%8f%e6%8b%93%e5%b1%95%e7%a0%94%e7%a9%b6%e6%95%b8%e6%93%9a%ef%bc%9a%e7%99%82%e6%95%88%e5%8f%af%e6%af%94","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=391581","title":{"rendered":"\u65b0\u6a4b\u751f\u7269\u516c\u4f48 Ragistomig 1\u671f\u5291\u91cf\u62d3\u5c55\u7814\u7a76\u6578\u64da\uff1a\u7642\u6548\u53ef\u6bd4\uff0c\u5b89\u5168\u6027\u986f\u8457\u63d0\u5347"},"content":{"rendered":"<div>\n<ul type=\"disc\">\n<li>Ragistomig \u662f\u4e00\u7a2e 4-1BB X PD-L1 \u96d9\u7279\u7570\u6027\u6297\u9ad4\uff0c\u65e8\u5728\u6cbb\u7642\u4f7f\u7528\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5f8c\u5fa9\u767c\u6216\u96e3\u6cbb\u7684\u665a\u671f\u6216\u8f49\u79fb\u6027\u5be6\u9ad4\u7624\u60a3\u8005\u3002\u4f5c\u70ba\u764c\u75c7\u6cbb\u7642\u7684\u652f\u67f1\uff0c\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5e02\u5834\u898f\u6a21\u9054\u6578\u5341\u5104\u7f8e\u5143\uff0c\u4f46\u5ee3\u6cdb\u5b58\u5728\u7684\u8010\u85e5\u6027\u9650\u5236\u4e86\u5176\u7642\u6548\u3002<\/li>\n<li>\u7814\u7a76\u76ee\u6a19\u5df2\u9054\u6210\uff1a\u5c0d\u65bc\u65e2\u5f80\u4f7f\u7528\u904e\u6297PD-(L)1\u7b49\u514d\u75ab\u7642\u6cd5\u5f8c\u96e3\u6cbb\u6216\u5fa9\u767c\u7684\u60a3\u8005\uff0c\u65b0\u7684\u6bcf6\u9031\u4e00\u6b21\uff08Q6W\uff09 \u5ef6\u9577\u7d66\u85e5\u9593\u9694\u65b9\u6848\u4e0d\u50c5\u5c55\u73fe\u51fa\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u6297\u816b\u7624\u7642\u6548\u548c\u514d\u75ab\u5b78\u6578\u64da\uff0c\u76f8\u8f03\u65bc\u6b64\u524d\u6bcf2\u9031\u4e00\u6b21\uff08Q2W\uff09\u7684\u65b9\u6848\uff0c\u5b89\u5168\u6027\u4e5f\u986f\u8457\u6539\u5584\u3002<\/li>\n<li>\u672c\u6b21\u767c\u4f48\u7684\u6d77\u5831\u5c55\u793a\u4e86\u5305\u542bCD8+ \u7d30\u80de\u589e\u6b96\u548c\u8a18\u61b6 T \u7d30\u80de\u6d3b\u5316\u5728\u5167\u7684\u7a4d\u6975\u514d\u75ab\u5b78\u6578\u64da\u3002<\/li>\n<\/ul>\n<p id=\"temp_ReleaseStart\"><span class=\"legendSpanClass\">\u99ac\u91cc\u862d\u5dde\u7f85\u514b\u7dad\u723e<\/span><span class=\"legendSpanClass\">2025\u5e7412\u670811\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; 12\u670811\u65e5\uff0c\u5168\u7403\u751f\u7269\u79d1\u6280\u5e73\u53f0\u516c\u53f8\u65b0\u6a4b\u751f\u7269\uff08NovaBridge Biosciences\uff1b\u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aNBP\uff0c\u4e0b\u7a31\u300c\u65b0\u6a4b\u751f\u7269\u300d\u6216\u300c\u516c\u53f8\u300d\uff09\u57282025\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\u514d\u75ab\u816b\u7624\u5b78\u5927\u6703\uff08ESMO-IO 2025\uff09\u4e0a\uff0c\u4ee5\u6d77\u5831\u5f62\u5f0f\u516c\u4f48\u4e86\u5176\u8207\u97d3\u570b\u516c\u53f8ABL Bio\u5171\u540c\u958b\u767c\u76844-1BB \u00d7 PD-L1\u96d9\u7279\u7570\u6027\u6297\u9ad4ragistomig\uff0c\u57283\u6beb\u514b\/\u5343\u514b\u5291\u91cf\u4e0b\u6bcf6\u9031\u4e00\u6b21\uff08Q6W\uff09 \u5ef6\u9577\u7d66\u85e5\u9593\u9694\u65b9\u6848\u76841\u671f\u7814\u7a76\u6700\u65b0\u6578\u64da\u3002<\/p>\n<p class=\"prntaj\">\u8a72\u6d77\u5831\u6458\u8981\u7de8\u865f#688\uff0c\u7531HealthONE Denver\u65d7\u4e0bSarah Cannon\u7814\u7a76\u6240\uff08SCRI\uff09\u4e3b\u4efbGerald Falchook\u535a\u58eb\u9032\u884c\u5c55\u793a\u3002\u6578\u64da\u986f\u793a\uff0c\u6bcf6\u9031\u4e00\u6b21\uff08Q6W\uff09\u7684\u65b0\u65b9\u6848\u5728\u55ae\u85e5\u6cbb\u7642\u4e2d\u5c55\u793a\u4e86\u7a69\u5b9a\u7684\u6297\u816b\u7624\u6d3b\u6027\uff0c\u4ee5\u53ca\u66f4\u597d\u7684\u514d\u75ab\u5b78\u7d42\u9ede\u548c\u8010\u53d7\u6027\u3002<\/p>\n<p class=\"prntaj\">\u65b0\u6a4b\u751f\u7269\u9996\u5e2d\u91ab\u5b78\u5b98 <span class=\"xn-person\">Phillip Dennis<\/span> \u535a\u58eb\u8868\u793a\uff1a\u300c\u4eca\u5929\u5728 ESMO-IO \u5927\u6703\u4e0a\u516c\u4f48\u7684ragistomig 1 \u671f\u5291\u91cf\u62d3\u5c55\u6578\u64da\u4ee4\u4eba\u632f\u596e\u3002\u4e4b\u524d\u7684Q2W \u65b9\u6848\u5df2\u5c55\u73fe\u51fa\u660e\u78ba\u7684\u81e8\u5e8a\u6d3b\u6027\uff0c\u65b0\u7684 Q6W \u7d66\u85e5\u9593\u9694\u5728\u4fdd\u8b49\u7642\u6548\u76f8\u7576\u7684\u57fa\u790e\u4e0a\uff0c\u5177\u6709\u66f4\u4f73\u7684\u5b89\u5168\u6027\u7279\u5fb5\u3002\u7814\u7a76\u7684\u76ee\u6a19\u5df2\u7d93\u9054\u5230\uff0c\u65e2\u62d3\u5c55\u4e86\u8a72\u85e5\u7269\u7684\u6cbb\u7642\u7a97\u53e3\uff0c\u4e5f\u70ba\u5176\u672a\u4f86\u9032\u5165\u806f\u5408\u7528\u85e5\u7814\u7a76\u968e\u6bb5\u63d0\u4f9b\u4e86\u6709\u529b\u652f\u6301\u3002\u5176\u4e2d\uff0c\u5927\u5e45\u6539\u5584\u7684\u5b89\u5168\u6027\u6578\u64da\u5c24\u5176\u4ee4\u4eba\u611f\u5230\u9f13\u821e\uff0c\u50c5\u67095%\u7684\u60a3\u8005\u809d\u529f\u80fd\u6aa2\u6e2c\u6307\u6a19\u5347\u9ad83\u7d1a\u53ca\u4ee5\u4e0a\uff0c\u514d\u75ab\u4ecb\u5c0e\u6d3b\u6027\u5247\u4fdd\u6301\u4e00\u81f4\u3002\u4ee5\u4e0a\u89c0\u5bdf\u7d50\u679c\uff0c\u7d50\u5408\u65b0\u65b9\u6848\u4e0d\u905c\u65bc\u5c0d\u7167\u7d44\u7684\u78ba\u8a8d\u7de9\u89e3\u7387\u548c\u6301\u4e45\u7684\u514d\u75ab\u6fc0\u6d3b\uff0c\u8b93\u6211\u5011\u6709\u4fe1\u5fc3\u8a8d\u70ba\uff0cragistomig \u6709\u6f5b\u529b\u70ba\u5fa9\u767c\u6216\u96e3\u6cbb\u7684\u5be6\u9ad4\u7624\u60a3\u8005\u63d0\u4f9b\u66f4\u6709\u6548\u7684\u6cbb\u7642\u3002\u300d<\/p>\n<p class=\"prntaj\">\u65b0\u6a4b\u751f\u7269\u9996\u5e2d\u57f7\u884c\u5b98 <span class=\"xn-person\">Sean Fu<\/span> \u535a\u58eb\u8868\u793a\uff1a\u300cRagistomig \u7684\u8a2d\u8a08\u521d\u8877\uff0c\u662f\u70ba\u4e86\u5e6b\u52a9\u63a5\u53d7\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u6cbb\u7642\u5f8c\u5fa9\u767c\u7684\u60a3\u8005\u514b\u670d\u8010\u85e5\u6027\u3002\u6211\u5011\u57282024\u5e74ASCO \u5927\u6703\u4e0a\u516c\u4f48\u7684\u6578\u64da\uff0c\u5df2\u5145\u5206\u5c55\u793a\u4e86\u8a72\u85e5\u7269\u7684\u5ee3\u95ca\u524d\u666f\u3002\u800c\u6b64\u756a\u5728ESMO-IO\u5927\u6703\u4e0a\u5c55\u793a\u7684\u6578\u64da\uff0c\u6b63\u662f\u5efa\u7acb\u5728\u6b64\u57fa\u790e\u4e4b\u4e0a\u3002\u65b0\u6a4b\u751f\u7269\u81f4\u529b\u65bc\u8207\u5168\u7403\u5275\u65b0\u8005\u651c\u624b\uff0c\u5171\u540c\u63a8\u52d5\u6f5b\u5728\u7684\u8b8a\u9769\u6027\u3001\u7a81\u7834\u6027\u7642\u6cd5\u7684\u767c\u5c55\uff0c\u800cragistomig\u9805\u76ee\u5247\u8207\u8a72\u6230\u7565\u9ad8\u5ea6\u5951\u5408\u3002\u6211\u5011\u71b1\u5207\u671f\u76fc\u8457\uff0c\u8207\u5408\u4f5c\u5925\u4f34ABL Bio\u5171\u540c\u555f\u52d5ragistomig\u806f\u5408\u7642\u6cd5\u7684\u7814\u7a76\u3002\u300d<\/p>\n<p class=\"prntaj\"><b>2025<\/b><b>\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\u514d\u75ab\u816b\u7624\u5b78\u5927\u6703<\/b><b>Ragistomig<\/b><b>\u6d77\u5831\u76f8\u95dc\u4fe1\u606f<\/b><\/p>\n<ul type=\"disc\">\n<li>\u6d77\u5831\u4e3b\u984c\uff1a Ragistomig\uff08ABL503\/TJ-L14B\uff1aPD-L1\u00d74-1BB\u96d9\u7279\u7570\u6027\u6297\u9ad4\uff09\u6bcf\u516d\u9031\u4e00\u6b21\u7684\u7d66\u85e5\u65b9\u6848\u7684\u2160\u671f\u81e8\u5e8a\u8a66\u9a57\uff0c\u901a\u904e\u5ef6\u9577\u514d\u75ab\u8a18\u61b6\u8207\u91cd\u632fCD8+ T\u7d30\u80de\uff0c\u5be6\u73fe\u5b89\u5168\u6027\u8207\u6301\u7e8c\u7642\u6548\u9593\u7684\u5e73\u8861<\/li>\n<li>\u6458\u8981\u7de8\u865f\uff1a#688\/\u6d77\u5831\u7de8\u865f\uff1a257P<\/li>\n<li>\u767c\u4f48\u6642\u9593\uff1a \u683c\u6797\u5a01\u6cbb\u6642\u95932025\u5e7412\u670810\u65e5\uff0c\u661f\u671f\u4e09\uff0c\u4e0b\u5348 5\u9ede15\u5206<\/li>\n<\/ul>\n<p class=\"prntaj\"><b>Ragistomig 1<\/b><b>\u671f\u55ae\u85e5\u6cbb\u7642<\/b><b> Q6W <\/b><b>\u6578\u64da<\/b><\/p>\n<p class=\"prntaj\">*\u6578\u64da\u622a\u6b62\u65e5\u671f\uff1a2025\u5e7410\u670822\u65e5<\/p>\n<ul type=\"disc\">\n<li>\u8207 Q2W \u65b9\u6848\u76f8\u6bd4\uff0cRagistomig \u5728 Q6W \u7d66\u85e5\u65b9\u6848\u4e2d\u8868\u73fe\u51fa\u53ef\u6bd4\u7684\u6297\u816b\u7624\u7642\u6548\u3002\u5176\u4e2d\uff0cQ6W \u7684\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u70ba 58.8%\uff0cQ2W\u5247\u70ba 64.3%\u3002<\/li>\n<li>Ragistomig \u5728Q6W \u7d44\u4e2d\u5c55\u73fe\u51fa\u4e86\u986f\u8457\u63d0\u5347\u7684\u826f\u597d\u5b89\u5168\u6027\uff0c20\u4f4d\u60a3\u8005\u4e2d\u50c51\u4eba\u7684\u809d\u529f\u80fd\u6aa2\u6e2c\u503c\u5347\u9ad83\u7d1a\u53ca\u4ee5\u4e0a\uff0c\u7121\u4eba\u56e0\u6cbb\u7642\u4e2d\u51fa\u73fe\u4e0d\u826f\u4e8b\u4ef6\uff08TEAEs\uff09\u800c\u505c\u85e5\uff0c\u4e14\u672a\u5831\u544a\u7d30\u80de\u56e0\u5b50\u91cb\u653e\u7d9c\u5408\u5f81\u3002<\/li>\n<li>Q6W \u548c Q2W \u7d66\u85e5\u7d44\u4e4b\u9593\u7684\u7e3d\u9ad4\u514d\u75ab\u7d30\u80de\u6d3b\u6027\u4e00\u81f4\u3002Q6W\u7d66\u85e5\u7d44\u7684\u514d\u75ab\u7d30\u80de\u85e5\u6548\u52d5\u529b\u5b78\u6578\u64da\u8868\u660e\uff0c\u6548\u61c9\u8a18\u61b6 T \u7d30\u80de\u548c CD8+ T \u7d30\u80de\u6709\u6240\u64f4\u589e\uff0c\u540c\u6642 Treg \u7d30\u80de\u7684\u64f4\u589e\u6e1b\u5f31\uff0c\u8868\u660e\u5b58\u5728\u6301\u4e45\u7684\u514d\u75ab\u6fc0\u6d3b\u3002<\/li>\n<li>\u7576\u524d\u6578\u64da\u70ba\u4ee5\u4e0b\u5169\u9805\u8a55\u4f30\u63d0\u4f9b\u4f9d\u64da\uff1a1\uff09\u6b63\u5728\u9032\u884c\u4ee55 \u6beb\u514b\/\u5343\u514b\u70ba\u5291\u91cf\u7684Q6W \u7d66\u85e5\u968a\u5217\u7684\u8a55\u4f30\uff1b2\uff09\u672a\u4f86\u5728\u806f\u5408\u7642\u6cd5\u7814\u7a76\u4e2d\u5c0dragistomig\u7684\u7528\u85e5\u8a55\u4f30\u3002<\/li>\n<\/ul>\n<p class=\"prntaj\"><b>\u60a3\u8005\u7279\u5fb5<\/b><\/p>\n<ul type=\"disc\">\n<li>\u7814\u7a76\u7d0d\u5165\u4e8620\u4f8b\u7d93\u904e\u591a\u7dda\u6cbb\u7642\u7684\u53d7\u8a66\u8005\uff0c\u63a5\u53d73 \u6beb\u514b\/\u516c\u65a4\u3001\u6bcf\u516d\u9031\u4e00\u6b21\u7684ragistomig\u6cbb\u7642\u3002\u8a72\u7d44\u60a3\u8005\u4e2d\uff0c100% \u63a5\u53d7\u904e\u514d\u75ab\u816b\u7624\u6cbb\u7642\uff0c70% \u65e2\u5f80\u63a5\u53d7\u904e 3 \u7dda\u53ca\u4ee5\u4e0a\u7cfb\u7d71\u6027\u6cbb\u7642\uff0c\u4e14\u5df2\u7528\u76e1\u6240\u6709\u53ef\u7528\u7684\u6a19\u6e96\u6cbb\u7642\u65b9\u6848\u3002<\/li>\n<li>\u76ee\u524d\u6709 10 \u540d\u60a3\u8005\u6b63\u5728\u63a5\u53d7 5 \u6beb\u514b\/\u5343\u514b\u5291\u91cf\u3001\u6bcf\u516d\u9031\u4e00\u6b21\u7684ragistomig \u6cbb\u7642\u3002<\/li>\n<\/ul>\n<p class=\"prntaj\"><b>\u7642\u6548\u7d50\u679c<\/b><\/p>\n<p class=\"prntaj\">*\u57fa\u65bc 17 \u540d\u53ef\u8a55\u4f30\u7684Q6W\u7d66\u85e5\u7d44\u60a3\u8005\u820714\u540d\u53ef\u8a55\u4f30\u7684Q2W\u7d66\u85e5\u7d44\u60a3\u8005\uff0c\u5291\u91cf\u5747\u70ba3\u6beb\u514b\/\u5343\u514b<\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prnpr2 prnpl2 prncbts prnbrbrs prnbbbs prnbsbls\" colspan=\"1\" rowspan=\"1\"><\/td>\n<td class=\"prngen3\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">Q6W\u7ed9\u836f\u7ec4<\/span><\/p>\n<\/td>\n<td class=\"prngen3\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">Q2W\u7ed9\u836f\u7ec4<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen4\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">\u90e8\u5206\u7f13\u89e3\u7387\uff08PR\uff09<\/span><\/p>\n<\/td>\n<td class=\"prngen5\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">11.8% \uff082\/17\uff09<\/span><\/p>\n<\/td>\n<td class=\"prngen5\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">28.6% \uff084\/14\uff09<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen4\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">\u75be\u75c5\u7a33\u5b9a\u7387\uff08SD\uff09<\/span><\/p>\n<\/td>\n<td class=\"prngen5\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">47.1% \uff088\/17\uff09<\/span><\/p>\n<\/td>\n<td class=\"prngen5\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">35.7% \uff085\/14\uff09<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen4\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09<\/span><\/p>\n<\/td>\n<td class=\"prngen5\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">58.8% \uff0810\/17\uff09<\/span><\/p>\n<\/td>\n<td class=\"prngen5\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prngen7\"><span class=\"prnews_span\">64.3% \uff089\/14\uff09<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p class=\"prntaj\"><b>\u5b89\u5168\u6027\u6578\u64da<\/b><\/p>\n<p class=\"prntaj\">*\u57fa\u65bc 20 \u540d\u53ef\u8a55\u4f30\u7684Q6W\u7d66\u85e5\u7d44\u60a3\u8005\u548c15 \u540d\u53ef\u8a55\u4f30\u7684Q2W\u7d66\u85e5\u7d44\u60a3\u8005\uff0c\u5291\u91cf\u5747\u70ba3\u6beb\u514b\/\u5343\u514b<\/p>\n<ul type=\"disc\">\n<li>Q6W\u7d66\u85e5\u7d44\u7684\u5b89\u5168\u6027\u986f\u8457\u6539\u5584\u3002<\/li>\n<li>3\u6beb\u514b\/\u5343\u514b\u5291\u91cf\u3001\u6bcf\u516d\u9031\u4e00\u6b21\u7684\u7d66\u85e5\u65b9\u6848\u88ab\u8a8d\u5b9a\u70ba\u806f\u5408\u6cbb\u7642\u7b56\u7565\u4e2d\u7684\u6f5b\u5728\u6700\u512a\u65b9\u6848\u3002<\/li>\n<li>\u809d\u529f\u80fd\u6aa2\u6e2c\u6307\u6a19\u5347\u9ad8\u90543\u7d1a\u53ca\u4ee5\u4e0a\u7684\u767c\u751f\u7387\uff0cQ6W\u7d44\u70ba5%\uff081\/20\uff09\uff0cQ2W\u7d44\u70ba33%\uff085\/15\uff09\u3002<\/li>\n<li>\u6cbb\u7642\u4e2d\u51fa\u73fe3\u7d1a\u53ca\u4ee5\u4e0a\u4e0d\u826f\u4e8b\u4ef6\u6bd4\u4f8b\uff1aQ6W\u7d44\u70ba50% \uff0810\/20\uff09\uff0cQ2W \u7d44\u70ba 66.7% \uff0810\/15\uff09\u3002\u5728 Q6W \u7d44\u4e2d\uff0c\u9019\u4e9b\u4e0d\u826f\u4e8b\u4ef6\uff08\u5305\u62ec\u809d\u529f\u80fd\u6aa2\u6e2c\u6307\u6a19\u5347\u9ad8\u3001\u8840\u5c0f\u677f\u8a08\u6578\u6e1b\u5c11\u3001\u8ca7\u8840\u548c\u4e2d\u6027\u7c92\u7d30\u80de\u8a08\u6578\u6e1b\u5c11\uff09\u5747\u5728 3\u81f314 \u5929 \u5167\u6062\u5fa9\uff08\u7121\u8ad6\u662f\u5426\u9032\u884c\u91ab\u7642\u5e72\u9810\uff09\uff0c\u4e14\u7121\u505c\u85e5\u4e8b\u4ef6\u3002<\/li>\n<li>\u5169\u7a2e\u7d66\u85e5\u65b9\u6848\u5747\u672a\u5831\u544a\u7d30\u80de\u56e0\u5b50\u91cb\u653e\u7d9c\u5408\u5f81\u75c5\u4f8b\u3002<\/li>\n<\/ul>\n<p class=\"prntaj\"><b>\u514d\u75ab\u5b78\u6578\u64da<\/b><\/p>\n<ul type=\"disc\">\n<li>\u6548\u61c9\u548c\u8a18\u61b6CD8+ T \u7d30\u80de\u4e9e\u7fa4\u6709\u6240\u589e\u52a0\uff0c\u5404\u7d66\u85e5\u7d44\u9593\u7684\u500d\u6578\u8b8a\u5316\u76f8\u7576\uff0c\u8868\u660e\u514d\u75ab\u4ecb\u5c0e\u7684\u85e5\u6548\u52d5\u529b\u5b78\u6d3b\u6027\u53ef\u80fd\u6709\u52a9\u65bc\u7642\u6548\u3002<\/li>\n<li>\u5728Q6W\u7d44\u4e2d\uff0cCTLA-4+ \u8abf\u7bc0\u6027T\u7d30\u80de\u7684\u6bd4\u4f8b\u7dad\u6301\u5728\u57fa\u7dda\u6c34\u5e73\u9644\u8fd1\uff0c\u8868\u660e\u5176\u66f4\u6709\u5229\u65bc\u6548\u61c9\u7d30\u80de\u8207\u8abf\u7bc0\u6027\u7d30\u80de\u4e4b\u9593\u7684\u5e73\u8861\u3002<\/li>\n<\/ul>\n<p class=\"prntaj\"><b>\u95dc\u65bc<\/b><b>Ragistomig<\/b><\/p>\n<p class=\"prntaj\">Ragistomig\uff08\u4ea6\u7a31ABL503\uff09\u7531\u65b0\u6a4b\u751f\u7269\u8207ABL Bio\u806f\u5408\u958b\u767c\uff0c\u662f\u4e00\u6b3e\u5dee\u7570\u5316\u7684\u65b0\u578b\u96d9\u7279\u7570\u6027\u6297\u9ad4\uff0c\u5176\u6574\u5408\u4e86\u4f5c\u70ba\u816b\u7624\u63a5\u5408\u5668\u7684\u55ae\u93c8\u3001Fc\u6c89\u9ed8\u7684PD-L1\u7247\u6bb5\u548c\u4f5c\u70ba\u689d\u4ef6\u6027T\u7d30\u80de\u6fc0\u6d3b\u5291\u76844-1BB\u7247\u6bb5\u3002\u5b83\u63a1\u7528ABL Bio\u7684\u300cGrabody-T\u300d\u96d9\u7279\u7570\u6027\u6297\u9ad4\u5e73\u53f0\u6280\u8853\u958b\u767c\uff0c\u65e8\u5728\u514b\u670dPD-(L)1\u6291\u5236\u5291\u7684\u8010\u85e5\u6027\uff0c\u4e26\u50c5\u5728PD-L1\u8868\u9054\u967d\u6027\u7684\u816b\u7624\u7d30\u80de\u5b58\u5728\u6642\u624d\u523a\u6fc04-1BB\u6fc0\u6d3b\uff0c\u4ee5\u6700\u5927\u9650\u5ea6\u5730\u964d\u4f4e\u812b\u9776\u6bd2\u6027\u98a8\u96aa\u3002\u81e8\u5e8a\u524d\u7814\u7a76\u8868\u660e\uff0c\u8a72\u96d9\u7279\u7570\u6027\u6297\u9ad4\u986f\u793a\u51fa\u6bd4\u5176\u55ae\u4e00\u7d44\u5206\u6297\u9ad4\u66f4\u512a\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002\u4e00\u98051\u671f\u5291\u91cf\u64f4\u5c55\u7814\u7a76\uff08NCT04762641\uff09\u76ee\u524d\u6b63\u5728\u7f8e\u570b\u53ca\u97d3\u570b\u9032\u884c\u3002\u8a72\u7814\u7a76\u7684\u4e3b\u8981\u7d42\u9ede\u662f\u78ba\u5b9aragistomig\u7684\u5291\u91cf\u9650\u5236\u6027\u6bd2\u6027\u548c\u4e0d\u826f\u4e8b\u4ef6\u7279\u5fb5\uff0c\u4e26\u89c0\u5bdf\u5ba2\u89c0\u7de9\u89e3\u7387\u3001\u85e5\u7269\u4ee3\u8b1d\u52d5\u529b\u5b78\u548c\u514d\u75ab\u539f\u6027\u7279\u5fb5\u4ee5\u53ca\u5176\u4ed6\u6b21\u8981\u7d42\u9ede\u3002<\/p>\n<p class=\"prntaj\"><b>\u95dc\u65bc\u65b0\u6a4b\u751f\u7269<\/b><\/p>\n<p class=\"prntaj\">\u65b0\u6a4b\u751f\u7269\u662f\u4e00\u5bb6\u5168\u7403\u751f\u7269\u79d1\u6280\u5e73\u53f0\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u52a0\u901f\u5275\u65b0\u85e5\u7269\u7684\u53ef\u53ca\u6027\u3002\u6211\u5011\u5c07\u5c08\u696d\u7684\u696d\u52d9\u62d3\u5c55\u80fd\u529b\u8207\u654f\u6377\u7684\u8f49\u5316\u81e8\u5e8a\u958b\u767c\u76f8\u7d50\u5408\uff0c\u4ee5\u767c\u73fe\u3001\u52a0\u901f\u4e26\u63a8\u9032\u7a81\u7834\u6027\u8cc7\u7522\u3002\u901a\u904e\u929c\u63a5\u79d1\u5b78\u3001\u6230\u7565\u548c\u57f7\u884c\uff0c\u65b0\u6a4b\u751f\u7269\u4f7f\u8b8a\u9769\u6027\u7642\u6cd5\u80fd\u5920\u5f9e\u767c\u73fe\u968e\u6bb5\u5feb\u901f\u63a8\u9032\u81f3\u6709\u9700\u6c42\u7684\u60a3\u8005\u3002\u516c\u53f8\u7684\u5dee\u7570\u5316\u7ba1\u7dda\u4e3b\u8981\u7531givastomig\u548cVIS-101\u9818\u929c\u3002\u5176\u4e2d\uff0cgivastomig\u662f\u4e00\u6b3e\u6f5b\u5728\u540c\u985e\u6700\u4f73\u7684\u96d9\u7279\u7570\u6027\u6297\u9ad4\uff08Claudin 18.2\u00d74-1BB\uff09\uff1bVIS-101\u662f\u4e00\u6b3e\u540c\u985e\u7b2c\u4e8c\u4e14\u6709\u671b\u6210\u70ba\u540c\u985e\u6700\u4f73\u7684\u96d9\u529f\u80fd\u751f\u7269\u5236\u5291\uff0c\u9776\u5411VEGF-A\u548cANG2\u3002Givastomig\u901a\u904e4-1BB\u4fe1\u865f\u901a\u8def\uff0c\u5728\u8868\u9054Claudin 18.2\u7684\u816b\u7624\u5fae\u74b0\u5883\u4e2d\u689d\u4ef6\u6027\u6fc0\u6d3bT\u7d30\u80de\u3002givastomig\u6b63\u958b\u767c\u7528\u65bc\u6cbb\u7642Claudin 18.2\u967d\u6027\u7684\u80c3\u764c\u53ca\u5176\u4ed6\u80c3\u8178\u9053\u60e1\u6027\u816b\u7624\u3002\u65b0\u6a4b\u751f\u7269\u9084\u8207\u5408\u4f5c\u5925\u4f34ABL Bio\u5408\u4f5c\u958b\u767cragistomig\uff0c\u9019\u662f\u4e00\u6b3e\u96d9\u7279\u7570\u6027\u6297\u9ad4\uff0c\u5728\u5be6\u9ad4\u7624\u4e2d\u5c07PD-L1\u4f5c\u70ba\u816b\u7624\u7d50\u5408\u9776\u9ede\u30014-1BB\u4f5c\u70ba\u689d\u4ef6\u6027T\u7d30\u80de\u6fc0\u6d3b\u5291\u3002\u6b64\u5916\uff0c\u65b0\u6a4b\u751f\u7269\u64c1\u6709uliledlimab\u5728\u4e2d\u570b\u4ee5\u5916\u5730\u5340\u7684\u5168\u7403\u6b0a\u76ca\u3002Uliledlimab\u662f\u4e00\u6b3e\u6297CD73\u6297\u9ad4\uff0c\u9776\u5411\u816b\u7624\u4e2d\u7531\u817a\u7518\u4ecb\u5c0e\u7684\u514d\u75ab\u6291\u5236\u3002VIS-101 \u9776\u5411 VEGF-A \u548c ANG2\uff0c\u53ef\u70ba\u6fd5\u6027\u5e74\u9f61\u76f8\u95dc\u6027\u9ec3\u6591\u8b8a\u6027\uff08wet AMD\uff09\u548c\u7cd6\u5c3f\u75c5\u6027\u9ec3\u6591\u6c34\u816b\uff08DME\uff09\u60a3\u8005\u63d0\u4f9b\u66f4\u5f37\u6709\u529b\u4e14\u6301\u4e45\u7684\u7642\u6548\u3002\u76ee\u524d\uff0cVIS-101 \u6b63\u5728\u958b\u5c55\u4e00\u9805\u91dd\u5c0d\u6fd5\u6027 AMD \u7684\u5927\u578b\u3001\u96a8\u6a5f\u3001\u5291\u91cf\u7bc4\u570d\u7684 II \u671f\u7814\u7a76\u3002\u65b0\u6a4b\u751f\u7269\u662f Visara \u7684\u63a7\u80a1\u80a1\u6771\uff0cVisara \u64c1\u6709 VIS-101 \u5728\u5927\u4e2d\u83ef\u5340\u53ca\u4e9e\u6d32\u67d0\u4e9b\u570b\u5bb6\u4ee5\u5916\u5168\u7403\u6b0a\u5229\u7684\u7368\u5bb6\u8a31\u53ef\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\uff1ahttps:\/\/www.novabridge.com<\/p>\n<p class=\"prntaj\"><b>\u524d\u77bb\u6027\u8072\u660e<\/b><\/p>\n<p class=\"prntaj\">\u672c\u516c\u544a\u5305\u542b\u524d\u77bb\u6027\u8072\u660e\u3002\u9019\u4e9b\u8072\u660e\u4f9d\u64da1995\u5e74\u7f8e\u570b\u300a\u79c1\u4eba\u8b49\u5238\u8a34\u8a1f\u6539\u9769\u6cd5\u6848\u300b\u7684\u300c\u5b89\u5168\u6e2f\u300d\u689d\u6b3e\u4f5c\u51fa\u3002\u53ef\u4ee5\u901a\u904e\u8853\u8a9e\u4f8b\u5982\u300c\u5c07\u300d\u3001\u300c\u9810\u8a08\u300d\u3001\u300c\u76f8\u4fe1\u300d\u3001\u300c\u65e8\u5728\u300d\u3001\u300c\u9810\u671f\u300d\u3001\u300c\u672a\u4f86\u300d\u3001\u300c\u6253\u7b97\u300d\u3001\u300c\u8a08\u5283\u300d\u3001\u300c\u6f5b\u5728\u300d\u3001\u300c\u4f30\u8a08\u300d\u3001\u300c\u6709\u4fe1\u5fc3\u300d\u7b49\u4ee5\u53ca\u985e\u4f3c\u8868\u8ff0\uff08\u6216\u5176\u53cd\u7fa9\u8868\u8ff0\uff09\u4f86\u8b58\u5225\u9019\u4e9b\u524d\u77bb\u6027\u8072\u660e\u3002\u65b0\u6a4b\u751f\u7269\u4e5f\u53ef\u80fd\u5728\u5176\u63d0\u4ea4\u7d66\u7f8e\u570b\u8b49\u5238\u4ea4\u6613\u59d4\u54e1\u6703\uff08SEC\uff09\u7684\u5b9a\u671f\u5831\u544a\u3001\u5411\u80a1\u6771\u767c\u4f48\u7684\u5e74\u5ea6\u5831\u544a\u3001\u65b0\u805e\u7a3f\u53ca\u5176\u4ed6\u66f8\u9762\u6750\u6599\u4e2d\uff0c\u4ee5\u53ca\u516c\u53f8\u9ad8\u7ba1\u3001\u8463\u4e8b\u6216\u54e1\u5de5\u5411\u7b2c\u4e09\u65b9\u6240\u4f5c\u7684\u53e3\u982d\u9673\u8ff0\u4e2d\u4f5c\u51fa\u66f8\u9762\u6216\u53e3\u982d\u7684\u524d\u77bb\u6027\u8072\u660e\u3002\u51e1\u4e0d\u5c6c\u65bc\u6b77\u53f2\u4e8b\u5be6\u7684\u9673\u8ff0\uff08\u5305\u62ec\u95dc\u65bc\u516c\u53f8\u7684\u4fe1\u5ff5\u548c\u9810\u671f\u7684\u9673\u8ff0\uff09\u5747\u70ba\u524d\u77bb\u6027\u8072\u660e\u3002\u672c\u65b0\u805e\u7a3f\u4e2d\u7684\u524d\u77bb\u6027\u8072\u660e\u5305\u62ec\u4f46\u4e0d\u9650\u65bc\u4ee5\u4e0b\u5167\u5bb9\uff1agivastomig\u3001VIS-101\u53ca\u516c\u53f8\u5176\u4ed6\u5019\u9078\u85e5\u7269\uff08\u5305\u62ecragistomig\uff09\u7684\u6230\u7565\u3001\u81e8\u5e8a\u958b\u767c\u3001\u8a08\u5283\u3001\u7d50\u679c\u3001\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\uff1b\u65b0\u6a4b\u751f\u7269\u5019\u9078\u85e5\u7269\uff08\u5305\u62ec givastomig \u3001ragistomig\u548c VIS-101\uff09\u7684\u6230\u7565\u8207\u81e8\u5e8a\u958b\u767c\uff1b\u9810\u671f\u7684\u81e8\u5e8a\u91cc\u7a0b\u7891\u548c\u7d50\u679c\u53ca\u76f8\u95dc\u6642\u9593\uff1b\u4ee5\u53ca\u65b0\u9818\u5c0e\u5c64\u4efb\u547d\u7684\u5f71\u97ff\u3002 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class=\"prntaj\"><b>\u65b0\u6a4b\u751f\u7269\u6295\u8cc7\u8005\u53ca\u5a92\u9ad4\u806f\u7e6b\u4eba<\/b><\/p>\n<p class=\"prntaj\">PJ Kelleher<br \/>LifeSci Advisors<br \/>+1-617-430-7579<br \/><a href=\"mailto:pkelleher@lifesciadvisors.com\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">pkelleher@lifesciadvisors.com<\/a><\/p>\n<p class=\"prntaj\">NovaBridge Biosciences<br \/>+1-240-745-6330<br \/><a href=\"mailto:IR@novabridge.com\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">IR@novabridge.com<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Ragistomig \u662f\u4e00\u7a2e &#8230;<\/p>\n","protected":false},"author":16,"featured_media":199219,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-391581","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u65b0\u6a4b\u751f\u7269\u516c\u4f48 Ragistomig 1\u671f\u5291\u91cf\u62d3\u5c55\u7814\u7a76\u6578\u64da\uff1a\u7642\u6548\u53ef\u6bd4\uff0c\u5b89\u5168\u6027\u986f\u8457\u63d0\u5347 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831<\/title>\n<meta name=\"description\" content=\"Ragistomig \u662f\u4e00\u7a2e 4-1BB X PD-L1 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\u7684\u5927\u578b\u3001\u96a8\u6a5f\u3001\u5291\u91cf\u7bc4\u570d\u7684 II \u671f\u7814\u7a76\u3002\u65b0\u6a4b\u751f\u7269\u662f Visara \u7684\u63a7\u80a1\u80a1\u6771\uff0cVisara \u64c1\u6709 VIS-101 \u5728\u5927\u4e2d\u83ef\u5340\u53ca\u4e9e\u6d32\u67d0\u4e9b\u570b\u5bb6\u4ee5\u5916\u5168\u7403\u6b0a\u5229\u7684\u7368\u5bb6\u8a31\u53ef\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\uff1ahttps:\/\/www.novabridge.com \u524d\u77bb\u6027\u8072\u660e 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givastomig \u3001ragistomig\u548c VIS-101\uff09\u7684\u6230\u7565\u8207\u81e8\u5e8a\u958b\u767c\uff1b\u9810\u671f\u7684\u81e8\u5e8a\u91cc\u7a0b\u7891\u548c\u7d50\u679c\u53ca\u76f8\u95dc\u6642\u9593\uff1b\u4ee5\u53ca\u65b0\u9818\u5c0e\u5c64\u4efb\u547d\u7684\u5f71\u97ff\u3002 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\u65b0\u6a4b\u751f\u7269\u6295\u8cc7\u8005\u53ca\u5a92\u9ad4\u806f\u7e6b\u4eba PJ KelleherLifeSci Advisors+1-617-430-7579pkelleher@lifesciadvisors.com NovaBridge Biosciences+1-240-745-6330IR@novabridge.com\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=391581\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u65b0\u6a4b\u751f\u7269\u516c\u4f48 Ragistomig 1\u671f\u5291\u91cf\u62d3\u5c55\u7814\u7a76\u6578\u64da\uff1a\u7642\u6548\u53ef\u6bd4\uff0c\u5b89\u5168\u6027\u986f\u8457\u63d0\u5347 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"Ragistomig \u662f\u4e00\u7a2e 4-1BB X PD-L1 \u96d9\u7279\u7570\u6027\u6297\u9ad4\uff0c\u65e8\u5728\u6cbb\u7642\u4f7f\u7528\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5f8c\u5fa9\u767c\u6216\u96e3\u6cbb\u7684\u665a\u671f\u6216\u8f49\u79fb\u6027\u5be6\u9ad4\u7624\u60a3\u8005\u3002\u4f5c\u70ba\u764c\u75c7\u6cbb\u7642\u7684\u652f\u67f1\uff0c\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5e02\u5834\u898f\u6a21\u9054\u6578\u5341\u5104\u7f8e\u5143\uff0c\u4f46\u5ee3\u6cdb\u5b58\u5728\u7684\u8010\u85e5\u6027\u9650\u5236\u4e86\u5176\u7642\u6548\u3002  \u7814\u7a76\u76ee\u6a19\u5df2\u9054\u6210\uff1a\u5c0d\u65bc\u65e2\u5f80\u4f7f\u7528\u904e\u6297PD-(L)1\u7b49\u514d\u75ab\u7642\u6cd5\u5f8c\u96e3\u6cbb\u6216\u5fa9\u767c\u7684\u60a3\u8005\uff0c\u65b0\u7684\u6bcf6\u9031\u4e00\u6b21\uff08Q6W\uff09 \u5ef6\u9577\u7d66\u85e5\u9593\u9694\u65b9\u6848\u4e0d\u50c5\u5c55\u73fe\u51fa\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u6297\u816b\u7624\u7642\u6548\u548c\u514d\u75ab\u5b78\u6578\u64da\uff0c\u76f8\u8f03\u65bc\u6b64\u524d\u6bcf2\u9031\u4e00\u6b21\uff08Q2W\uff09\u7684\u65b9\u6848\uff0c\u5b89\u5168\u6027\u4e5f\u986f\u8457\u6539\u5584\u3002  \u672c\u6b21\u767c\u4f48\u7684\u6d77\u5831\u5c55\u793a\u4e86\u5305\u542bCD8+ \u7d30\u80de\u589e\u6b96\u548c\u8a18\u61b6 T \u7d30\u80de\u6d3b\u5316\u5728\u5167\u7684\u7a4d\u6975\u514d\u75ab\u5b78\u6578\u64da\u3002  \u99ac\u91cc\u862d\u5dde\u7f85\u514b\u7dad\u723e2025\u5e7412\u670811\u65e5 \/\u7f8e\u901a\u793e\/ -- 12\u670811\u65e5\uff0c\u5168\u7403\u751f\u7269\u79d1\u6280\u5e73\u53f0\u516c\u53f8\u65b0\u6a4b\u751f\u7269\uff08NovaBridge Biosciences\uff1b\u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aNBP\uff0c\u4e0b\u7a31\u300c\u65b0\u6a4b\u751f\u7269\u300d\u6216\u300c\u516c\u53f8\u300d\uff09\u57282025\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\u514d\u75ab\u816b\u7624\u5b78\u5927\u6703\uff08ESMO-IO 2025\uff09\u4e0a\uff0c\u4ee5\u6d77\u5831\u5f62\u5f0f\u516c\u4f48\u4e86\u5176\u8207\u97d3\u570b\u516c\u53f8ABL Bio\u5171\u540c\u958b\u767c\u76844-1BB \u00d7 PD-L1\u96d9\u7279\u7570\u6027\u6297\u9ad4ragistomig\uff0c\u57283\u6beb\u514b\/\u5343\u514b\u5291\u91cf\u4e0b\u6bcf6\u9031\u4e00\u6b21\uff08Q6W\uff09 \u5ef6\u9577\u7d66\u85e5\u9593\u9694\u65b9\u6848\u76841\u671f\u7814\u7a76\u6700\u65b0\u6578\u64da\u3002 \u8a72\u6d77\u5831\u6458\u8981\u7de8\u865f#688\uff0c\u7531HealthONE Denver\u65d7\u4e0bSarah Cannon\u7814\u7a76\u6240\uff08SCRI\uff09\u4e3b\u4efbGerald Falchook\u535a\u58eb\u9032\u884c\u5c55\u793a\u3002\u6578\u64da\u986f\u793a\uff0c\u6bcf6\u9031\u4e00\u6b21\uff08Q6W\uff09\u7684\u65b0\u65b9\u6848\u5728\u55ae\u85e5\u6cbb\u7642\u4e2d\u5c55\u793a\u4e86\u7a69\u5b9a\u7684\u6297\u816b\u7624\u6d3b\u6027\uff0c\u4ee5\u53ca\u66f4\u597d\u7684\u514d\u75ab\u5b78\u7d42\u9ede\u548c\u8010\u53d7\u6027\u3002 \u65b0\u6a4b\u751f\u7269\u9996\u5e2d\u91ab\u5b78\u5b98 Phillip Dennis \u535a\u58eb\u8868\u793a\uff1a\u300c\u4eca\u5929\u5728 ESMO-IO \u5927\u6703\u4e0a\u516c\u4f48\u7684ragistomig 1 \u671f\u5291\u91cf\u62d3\u5c55\u6578\u64da\u4ee4\u4eba\u632f\u596e\u3002\u4e4b\u524d\u7684Q2W \u65b9\u6848\u5df2\u5c55\u73fe\u51fa\u660e\u78ba\u7684\u81e8\u5e8a\u6d3b\u6027\uff0c\u65b0\u7684 Q6W 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