{"id":38009,"date":"2020-03-15T10:05:36","date_gmt":"2020-03-15T10:05:36","guid":{"rendered":"http:\/\/pingtungtimes.com.tw\/?p=38009"},"modified":"2020-03-15T10:05:41","modified_gmt":"2020-03-15T10:05:41","slug":"%e8%87%ba%e7%be%8e%e8%ab%96%e6%88%b0%e3%80%80%e7%ad%86%e6%88%b0%e6%99%82%e7%96%ab","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=38009","title":{"rendered":"\u81fa\u7f8e\u8ad6\u6230\u3000\u7b46\u6230\u6642\u75ab"},"content":{"rendered":"\n

\u3010\u674e\u91cd\u5fb7\uff0f\u5c08\u6b04\u5831\u5c0e2020\/3\/14\u3011\u3000\u91cd\u5fb7 \u56e0\u70ba\u653f\u6cbb\u7acb\u5834\u56e0\u7d20\u800c\u5728\u201c\u81fa\u5357\u4e00\u4e2d1976\u201d\u7fa4\u7d44\u4e2d\u81ea\u6211\u7981\u8a00\uff0c\u8a72\u7fa4\u7d44156\u4eba\u5927\u591a\u662f\u8207 \u91cd\u5fb7 \u540c\u5c46\u7684\u540c\u5b78\uff0c\u4f46\u662f\u591a\u6578\u662f\u535a\u58eb\uff0c\u91ab\u751f\u7279\u5225\u591a\uff0c\u4e5f\u6709\u7d04\u4e09\u5206\u4e4b\u4e00\u662f\u65c5\u5c45\u7f8e\u570b\u3002<\/p>\n\n\n\n

\u7531\u65bc\u90fd\u662f\u83c1\u82f1\u4efd\u5b50\uff0c\u56e0\u6b64\u8ab0\u4e5f\u4e0d\u670d\u8ab0\uff0c\u5c24\u5176\u6975\u5c11\u7684\u4e00\u4e8c\u4f4d\u653f\u6cbb\u7acb\u5834\u50be\u4e2d\u7684\u4eba\u58eb\u7e3d\u6703\u5728\u7fa4\u7d44\u4e2d\u6311\u6230\u540c\u5b78\u7684\u601d\u60f3\u908f\u8f2f\uff0c\u70ba\u5176\u8a8d\u77e5\u7684\u7956\u570b\u8faf\u8b77\uff0c\u56e0\u6b64 \u91cd\u5fb7 \u8207\u5176\u4ed6\u8a31\u591a\u5177\u6709\u516c\u773e\u4eba\u7269\u8eab\u5206\u7684\u540c\u5b78\u66f4\u662f\u4e0d\u9858\u610f\u767c\u8868\u4efb\u4f55\u610f\u898b\uff0c\u4ee5\u514d\u6372\u5165\u7121\u8b02\u7684\u8ad6\u6230\u4e4b\u4e2d\u3002<\/p>\n\n\n\n

\u4f46\u662f\u4ee5\u4e0b\u7684\u4e00\u500b\u6709\u95dc\u91ab\u5b78\u7684\u8ad6\u6230\uff0c\u91cd\u5fb7 \u89ba\u5f97\u53ef\u4ee5\u8f49\u8ff0\u7d66\u76f8\u95dc\u4eba\u54e1\u53c3\u8003\uff0c\u4f46\u5176\u7576\u4e8b\u4eba\u7684\u540d\u7a31\u90fd\u5df2\u8b8a\u9020\uff1a<\/p>\n\n\n\n

\u525b\u525b\u5f15\u767c\u7684\u4e00\u5834\u6d89\u53ca\u5169\u5cb8\u653f\u6cbb\u7684\u201c\u75ab\u60c5\u771f\u5047\u201d\u7684\u8faf\u8ad6\uff0c\u7531\u672c\u73ed\u7684\u9673\u540c\u5b78\u4ee5\u4e0b\u9762\u7684\u4e00\u6bb5\u8a71\u66ab\u6642\u4f86\u6b62\u606f\u6230\u706b\uff0c\u4e26\u91cd\u65b0\u9ede\u71c3\u53e6\u4e00\u5834\u91ab\u7642\u65b9\u6cd5\u7684\u6230\u706b\uff1a<\/p>\n\n\n\n

\u25cf Dr. Chen\uff1a<\/p>\n\n\n\n

\u5728\u7f8e\u770b\u83ef\u8a9e\u96fb\u8996, \u5927\u9678\u65b0\u805e\u5831\u5c0e\u7684\u7f8e\u570b\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1, \u53f0\u7063\u65b0\u805e\u5831\u5c0e\u7684\u5927\u9678\u65b0\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1.<\/p>\n\n\n\n

\u25cf Dr. Spencer\uff1a<\/p>\n\n\n\n

\u4ee5\u76ee\u524d\u5728\u6aa2\u6e2c\u4e0d\u8db3\u548c\u5df2\u78ba\u75b9\u75c5\u4eba\u7684\u5206\u4f48\u60c5\u6cc1\u4f86\u770b\uff0c\u7f8e\u570b\u75ab\u60c5\u7206\u767c\u662f\u7121\u53ef\u907f\u514d\u3002\u75ab\u60c5\u7206\u767c\u5f8c ICU \u76ee\u524d\u7684\u5e8a\u4f4d\u4e0d\u8db3\uff0c\u547c\u5438\u673a\u4e0d\u5920\uff0c\u9019\u90fd\u6703\u662f\u554f\u984c\u3002Lombardy, Italy \u662f\u6b50\u6d32\u533b\u7642\u6700\u5148\u9032\u7684\u5340\u57df\u4e4b\u4e00\uff0c\u770b\u770b\u4ed6\u5011\u73fe\u5728\u533b\u7642\u80fd\u529b\u9060\u9060\u900f\u652f\u7684\u6158\u72c0\u3002<\/p>\n\n\n\n

\u25cf Dr. Y-C,Hung\uff1a<\/p>\n\n\n\n

\u554f\u984c\u662f\u6240\u4f7f\u7528\u7684\u5291\u91cf\u6709\u7121\u6b64\u6548\u7528\uff0c\u548c\u4ec0\u9ebc\u6642\u5019\u7528\u3002\u7406\u8ad6\u4e0a\u9019\u61c9\u8a72\u5f88\u65e9\u7528\uff0c\u7528\u5728\u4ec0\u9ebc\u6a23\u7684\u4eba\u3002\u591a\u6578\u4eba\u75c7\u72c0\u90fd\u5f88\u8efd\uff0c\u6240\u4ee5\u5373\u4f7f\u4e0d\u6cbb\u7642\u4e5f\u6703\u597d\u3002\u5728\u9019\u7a2e\u60c5\u6cc1\u4e0b\uff0c\u4f7f chloroquin \u6216\u662f\u5176\u4ed6\u85e5\u5373\u4f7f\u4ed6\u5011\u526f\u4f5c\u7528\u4e0d\u5927\u5728\u91ab\u5b78\u4e0a\u662f risk \u5927\u65bc\nbenefit.<\/p>\n\n\n\n

\u5f88\u591a\u5728 in vitro \u7528\u7684\u5291\u91cf\u548c\u6fc3\u5ea6\u662f\u7d66\u4eba\u9ad4\u4f7f\u7528\u7684\u6642\u5019\u9054\u4e0d\u5230\u7684\u3002<\/p>\n\n\n\n

\u7528\u5728\u6cbb\u7642\u7627\u75be\u4e0d\u540c\uff0c\u56e0\u70ba\u539f\u87f2\u5728\u7d05\u8840\u7403\u5167\uff0c chloroquin \u7684\u6fc3\u5ea6\u6bd4\u8f03\u5bb9\u6613\u9054\u5230\u3002corona\nvirus \u662f\u5f71\u97ff\u80ba\u90e8\u8868\u76ae\u7d30\u80de\uff0c\u85e5\u5fc5\u9808\u5f9e\u5e95\u90e8\u7684\u8840\u7ba1\u6ef2\u900f\u9032\u4f86\uff0c\u6240\u4ee5\u53ef\u80fd\u9700\u8981\u5f88\u9ad8\u5291\u91cf\u624d\u80fd\u9054\u5230 in vitro \u7684\u6fc3\u5ea6\u3002\u5728\u505a\u7d30\u80de\u5be6\u9a57\u6642\uff0c\u85e5\u90fd\u662f\u76f4\u63a5\u653e\u5728\u7d30\u80de\u7684\u8868\u9762\u3002<\/p>\n\n\n\n

\u25cf Dr. Spencer\uff1a<\/p>\n\n\n\n

In the journal from\nKorea:<\/p>\n\n\n\n

Quote:<\/p>\n\n\n\n

For the antiviral\ntreatment, the doctors recommended lopinavir 400mg\/ritonavir 100mg (Kaletra two\ntablets, twice a day) or chloroquine 500mg orally per day.<\/p>\n\n\n\n

As chloroquine is not\navailable in Korea, doctors could consider hydroxychloroquine 400mg orally per\nday, they said. There is no evidence that using lopinavir\/ritonavir with\nchloroquine is more effective than monotherapies, they added.<\/p>\n\n\n\n

In contrast, Chinese\ndoctors recommend in their journal article to take chloroquine 500mg orally\ntwice per day.<\/p>\n\n\n\n

\u25cf Dr. Robin\uff1a<\/p>\n\n\n\n

Based on\nclinicaltrials.gov info, Remdesivir studies are IV infusion of 40 mL in 3\nhours, loading dose of 200mg and maintenance dose of 100mg for 4 or 9 days.\nAssuming efficacious, it is difficult to implement in pandemic situation.\nWouldn’t SC infusion be much easier to implement in a pandemic situation? I am\nhoping to look into this via BMGF for its PK, safety\/efficacy and tolerability.\nWill contact you privately.<\/p>\n\n\n\n

\u25cf Dr. Y-C,Hung\uff1a<\/p>\n\n\n\n

These are\nrecommendations based on no evidence, something we call it expert opinion, the\nlowest level in evidence-based medicine.<\/p>\n\n\n\n

\u5982\u679c\u662f clinical trials \u7684\u4e00\u90e8\u5206\uff0c\u90a3\u662f\u53ef\u4ee5\u63a5\u53d7\u7684\uff0c\u4f46\u662f\u7528\u5728\u6240\u6709\u4eba\u662f\u9055\u53cd\u91ab\u5b78\u4e0a\u7684\u7b2c\u4e00\u539f\u5247\uff0cDo no harm.<\/p>\n\n\n\n

\u25cf Dr. Spencer\uff1a<\/p>\n\n\n\n

\nhttps:\/\/www.bbc.com\/news\/amp\/technology-51851292\n<\/div><\/figure>\n\n\n\n

Coronavirus: How can\nAI help fight the pandemic?  BBC<\/p>\n\n\n\n

\u25cf Dr. Spencer\uff1a<\/p>\n\n\n\n

\nhttps:\/\/cms.wj411.com\/portal\/index\/newshare_weibo.jsp?id=2217380&source=13\n<\/div><\/figure>\n\n\n\n

\u25cf \u5f90\u91ab\u5e2b\uff1a<\/p>\n\n\n\n

\u7fa9\u5927\u5229\u6b7b\u4ea1\u7387\u9ad8\u5f97\u96e2\u5947\uff01\u6bba\u4eba\u5147\u624b\u662f\u9023\u7e8c10\u5e74\u7684\u7dca\u7e2e\u653f\u7b56\uff01<\/p>\n\n\n\n

\u622a\u81f33\u670813\u65e5\uff0c\u7fa9\u5927\u5229\u7684\u6b7b\u4ea1\u7387\u78346.7\uff05\uff0c\u5168\u7403\u4e4b\u6700\uff01<\/p>\n\n\n\n

\u5168\u7403\u570b\u5bb6\u8001\u5316\u7a0b\u5ea6\u6392\u540d\uff1a<\/p>\n\n\n\n

\u51a0\u8ecd\uff1a\u65e5\u672c27%<\/p>\n\n\n\n

\u4e9e\u8ecd\uff1a\u7fa9\u5927\u522923%<\/p>\n\n\n\n

\u5b63\u8ecd\uff1a\u5fb7\u570b21%<\/p>\n\n\n\n

\u6b64\u6b21\u6b66\u6f22\u75c5\u6bd2\u6b7b\u4ea1\u7387\uff1a<\/p>\n\n\n\n

\u7fa9\u5927\u5229\uff1a6.7%<\/p>\n\n\n\n

\u65e5\u672c\uff1a2.8%<\/p>\n\n\n\n

\u5fb7\u570b\uff1a0.2%<\/p>\n\n\n\n

\u90fd\u7a81\u986f\u7fa9\u5927\u5229\u7684\u9ad8\u6b7b\u4ea1\u7387\u4e0d\u5408\u7406\u3002<\/p>\n\n\n\n

\u7f8e\u570b\u5a92\u9ad4\u300a\u83ef\u723e\u8857\u65e5\u5831\u300b\uff08Wall Street Journal\uff09\u5f15\u7576\u5730\u570b\u5bb6\u885b\u751f\u5c40\u7d71\u8a08\u6578\u64da\uff1a<\/p>\n\n\n\n

\u81f3\u4eca\u6b66\u80ba\u6b7b\u8005\u4e2d\uff0c<\/p>\n\n\n\n

58%\u5e74\u9f61\u8d85\u904e80\u6b72\u3001<\/p>\n\n\n\n

31%\u843d\u572870\u591a\u6b72\u3002<\/p>\n\n\n\n

\u5e15\u591a\u74e6\u5927\u5b78\uff08University of Padua\uff09\u75c5\u6bd2\u5b78\u5bb6\u5e15\u9b6f\uff08Giorgio Pal\u00f9\uff09\u8aaa\uff1a\u300c\u751f\u7269\u5b78\u7684\u89d2\u5ea6\u7121\u6cd5\u89e3\u91cb\uff0c\u552f\u4e00\u80af\u5b9a\u7684\u662f\uff0c\u7fa9\u5927\u5229\u582a\u7a31\u5168\u4e16\u754c\u4eba\u53e3\u6700\u5e74\u8001\u7684\u570b\u5bb6\u4e4b\u4e00\u3002\u300d<\/p>\n\n\n\n

\u25cf Dr. Chen\uff1a<\/p>\n\n\n\n

\nhttps:\/\/zh.wikipedia.org\/wiki\/%E5%AE%89%E4%B8%9C%E5%B0%BC%C2%B7%E5%BC%97%E5%A5%91\n<\/div><\/figure>\n\n\n\n

\u5b89\u4e86\uff01\uff08\u5ddd\u666e\u8001\u4eba\u958b\u807d\u6bd4\u4ed6\u9084\u8001\u7684\u5b89\u6771\u5c3c.\u5f17\u5951\u5c08\u5bb6\uff09<\/p>\n\n\n\n

\u9019\u500b\u6642\u5019\uff0c\u642c\u6f14\u548c\u4e8b\u4f6c\u7684\u9673\u540c\u5b78\u53c8\u51fa\u4f86\u6253\u5713\u5834\u4e86\uff0c\u5176\u5be6\u9673\u540c\u5b78\u624d\u662f\u771f\u6b63\u7684\u91ab\u5b78\u5c08\u5bb6\uff0c\u56e0\u70ba\u4ed6\u670d\u52d9\u7684\u516c\u53f8\u662f\u5168\u5e02\u6700\u5927\u91ab\u7642\u96c6\u5718BD\u516c\u53f8\u3002<\/p>\n\n\n\n

\"\"
\u25b2\u64da\u6d88\u606f\u4eba\u58eb\u7a31\uff0c\u6839\u64da\u7f8e\u570b\u60c5\u5831\u6a5f\u69cb\u7684\u60c5\u5831\u986f\u793a\uff0c\u4e2d\u5171\u9ad8\u5c64\u6b63\u6e96\u5099\u300c\u672b\u65e5\u9003\u96e3\u8a08\u756b\u300d\u3002\uff08\u5716\uff0fAdobe stock\uff09<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"

\u3010\u674e\u91cd\u5fb7\uff0f\u5c08\u6b04\u5831\u5c0e2020\/3…<\/p>\n","protected":false},"author":1,"featured_media":38010,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[11],"tags":[10212,10209,10210,10211],"class_list":["post-38009","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-11","tag-10212","tag-10209","tag-10210","tag-10211"],"acf":[],"yoast_head":"\n\u81fa\u7f8e\u8ad6\u6230\u3000\u7b46\u6230\u6642\u75ab - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831<\/title>\n<meta name=\"description\" content=\"\u3010\u674e\u91cd\u5fb7\uff0f\u5c08\u6b04\u5831\u5c0e2020\/3\/14\u3011\u3000\u91cd\u5fb7 \u56e0\u70ba\u653f\u6cbb\u7acb\u5834\u56e0\u7d20\u800c\u5728\u201c\u81fa\u5357\u4e00\u4e2d1976\u201d\u7fa4\u7d44\u4e2d\u81ea\u6211\u7981\u8a00\uff0c\u8a72\u7fa4\u7d44156\u4eba\u5927\u591a\u662f\u8207 \u91cd\u5fb7 \u540c\u5c46\u7684\u540c\u5b78\uff0c\u4f46\u662f\u591a\u6578\u662f\u535a\u58eb\uff0c\u91ab\u751f\u7279\u5225\u591a\uff0c\u4e5f\u6709\u7d04\u4e09\u5206\u4e4b\u4e00\u662f\u65c5\u5c45\u7f8e\u570b\u3002 \u7531\u65bc\u90fd\u662f\u83c1\u82f1\u4efd\u5b50\uff0c\u56e0\u6b64\u8ab0\u4e5f\u4e0d\u670d\u8ab0\uff0c\u5c24\u5176\u6975\u5c11\u7684\u4e00\u4e8c\u4f4d\u653f\u6cbb\u7acb\u5834\u50be\u4e2d\u7684\u4eba\u58eb\u7e3d\u6703\u5728\u7fa4\u7d44\u4e2d\u6311\u6230\u540c\u5b78\u7684\u601d\u60f3\u908f\u8f2f\uff0c\u70ba\u5176\u8a8d\u77e5\u7684\u7956\u570b\u8faf\u8b77\uff0c\u56e0\u6b64 \u91cd\u5fb7 \u8207\u5176\u4ed6\u8a31\u591a\u5177\u6709\u516c\u773e\u4eba\u7269\u8eab\u5206\u7684\u540c\u5b78\u66f4\u662f\u4e0d\u9858\u610f\u767c\u8868\u4efb\u4f55\u610f\u898b\uff0c\u4ee5\u514d\u6372\u5165\u7121\u8b02\u7684\u8ad6\u6230\u4e4b\u4e2d\u3002 \u4f46\u662f\u4ee5\u4e0b\u7684\u4e00\u500b\u6709\u95dc\u91ab\u5b78\u7684\u8ad6\u6230\uff0c\u91cd\u5fb7 \u89ba\u5f97\u53ef\u4ee5\u8f49\u8ff0\u7d66\u76f8\u95dc\u4eba\u54e1\u53c3\u8003\uff0c\u4f46\u5176\u7576\u4e8b\u4eba\u7684\u540d\u7a31\u90fd\u5df2\u8b8a\u9020\uff1a \u525b\u525b\u5f15\u767c\u7684\u4e00\u5834\u6d89\u53ca\u5169\u5cb8\u653f\u6cbb\u7684\u201c\u75ab\u60c5\u771f\u5047\u201d\u7684\u8faf\u8ad6\uff0c\u7531\u672c\u73ed\u7684\u9673\u540c\u5b78\u4ee5\u4e0b\u9762\u7684\u4e00\u6bb5\u8a71\u66ab\u6642\u4f86\u6b62\u606f\u6230\u706b\uff0c\u4e26\u91cd\u65b0\u9ede\u71c3\u53e6\u4e00\u5834\u91ab\u7642\u65b9\u6cd5\u7684\u6230\u706b\uff1a \u25cf Dr. Chen\uff1a \u5728\u7f8e\u770b\u83ef\u8a9e\u96fb\u8996, \u5927\u9678\u65b0\u805e\u5831\u5c0e\u7684\u7f8e\u570b\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1, \u53f0\u7063\u65b0\u805e\u5831\u5c0e\u7684\u5927\u9678\u65b0\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1. \u25cf Dr. Spencer\uff1a \u4ee5\u76ee\u524d\u5728\u6aa2\u6e2c\u4e0d\u8db3\u548c\u5df2\u78ba\u75b9\u75c5\u4eba\u7684\u5206\u4f48\u60c5\u6cc1\u4f86\u770b\uff0c\u7f8e\u570b\u75ab\u60c5\u7206\u767c\u662f\u7121\u53ef\u907f\u514d\u3002\u75ab\u60c5\u7206\u767c\u5f8c ICU \u76ee\u524d\u7684\u5e8a\u4f4d\u4e0d\u8db3\uff0c\u547c\u5438\u673a\u4e0d\u5920\uff0c\u9019\u90fd\u6703\u662f\u554f\u984c\u3002Lombardy, Italy \u662f\u6b50\u6d32\u533b\u7642\u6700\u5148\u9032\u7684\u5340\u57df\u4e4b\u4e00\uff0c\u770b\u770b\u4ed6\u5011\u73fe\u5728\u533b\u7642\u80fd\u529b\u9060\u9060\u900f\u652f\u7684\u6158\u72c0\u3002 \u25cf Dr. Y-C,Hung\uff1a \u554f\u984c\u662f\u6240\u4f7f\u7528\u7684\u5291\u91cf\u6709\u7121\u6b64\u6548\u7528\uff0c\u548c\u4ec0\u9ebc\u6642\u5019\u7528\u3002\u7406\u8ad6\u4e0a\u9019\u61c9\u8a72\u5f88\u65e9\u7528\uff0c\u7528\u5728\u4ec0\u9ebc\u6a23\u7684\u4eba\u3002\u591a\u6578\u4eba\u75c7\u72c0\u90fd\u5f88\u8efd\uff0c\u6240\u4ee5\u5373\u4f7f\u4e0d\u6cbb\u7642\u4e5f\u6703\u597d\u3002\u5728\u9019\u7a2e\u60c5\u6cc1\u4e0b\uff0c\u4f7f chloroquin \u6216\u662f\u5176\u4ed6\u85e5\u5373\u4f7f\u4ed6\u5011\u526f\u4f5c\u7528\u4e0d\u5927\u5728\u91ab\u5b78\u4e0a\u662f risk \u5927\u65bc benefit. \u5f88\u591a\u5728 in vitro \u7528\u7684\u5291\u91cf\u548c\u6fc3\u5ea6\u662f\u7d66\u4eba\u9ad4\u4f7f\u7528\u7684\u6642\u5019\u9054\u4e0d\u5230\u7684\u3002 \u7528\u5728\u6cbb\u7642\u7627\u75be\u4e0d\u540c\uff0c\u56e0\u70ba\u539f\u87f2\u5728\u7d05\u8840\u7403\u5167\uff0c chloroquin \u7684\u6fc3\u5ea6\u6bd4\u8f03\u5bb9\u6613\u9054\u5230\u3002corona virus \u662f\u5f71\u97ff\u80ba\u90e8\u8868\u76ae\u7d30\u80de\uff0c\u85e5\u5fc5\u9808\u5f9e\u5e95\u90e8\u7684\u8840\u7ba1\u6ef2\u900f\u9032\u4f86\uff0c\u6240\u4ee5\u53ef\u80fd\u9700\u8981\u5f88\u9ad8\u5291\u91cf\u624d\u80fd\u9054\u5230 in vitro \u7684\u6fc3\u5ea6\u3002\u5728\u505a\u7d30\u80de\u5be6\u9a57\u6642\uff0c\u85e5\u90fd\u662f\u76f4\u63a5\u653e\u5728\u7d30\u80de\u7684\u8868\u9762\u3002 \u25cf Dr. Spencer\uff1a In the journal from Korea: Quote: For the antiviral treatment, the doctors recommended lopinavir 400mg\/ritonavir 100mg (Kaletra two tablets, twice a day) or chloroquine 500mg orally per day. As chloroquine is not available in Korea, doctors could consider hydroxychloroquine 400mg orally per day, they said. There is no evidence that using lopinavir\/ritonavir with chloroquine is more effective than monotherapies, they added. In contrast, Chinese doctors recommend in their journal article to take chloroquine 500mg orally twice per day. \u25cf Dr. Robin\uff1a Based on clinicaltrials.gov info, Remdesivir studies are IV infusion of 40 mL in 3 hours, loading dose of 200mg and maintenance dose of 100mg for 4 or 9 days. Assuming efficacious, it is difficult to implement in pandemic situation. Wouldn't SC infusion be much easier to implement in a pandemic situation? I am hoping to look into this via BMGF for its PK, safety\/efficacy and tolerability. Will contact you privately. \u25cf Dr. Y-C,Hung\uff1a These are recommendations based on no evidence, something we call it expert opinion, the lowest level in evidence-based medicine. \u5982\u679c\u662f clinical trials \u7684\u4e00\u90e8\u5206\uff0c\u90a3\u662f\u53ef\u4ee5\u63a5\u53d7\u7684\uff0c\u4f46\u662f\u7528\u5728\u6240\u6709\u4eba\u662f\u9055\u53cd\u91ab\u5b78\u4e0a\u7684\u7b2c\u4e00\u539f\u5247\uff0cDo no harm. \u25cf Dr. Spencer\uff1a https:\/\/www.bbc.com\/news\/amp\/technology-51851292 Coronavirus: How can AI help fight the pandemic?  BBC \u25cf Dr. Spencer\uff1a https:\/\/cms.wj411.com\/portal\/index\/newshare_weibo.jsp?id=2217380&source=13 \u25cf \u5f90\u91ab\u5e2b\uff1a \u7fa9\u5927\u5229\u6b7b\u4ea1\u7387\u9ad8\u5f97\u96e2\u5947\uff01\u6bba\u4eba\u5147\u624b\u662f\u9023\u7e8c10\u5e74\u7684\u7dca\u7e2e\u653f\u7b56\uff01 \u622a\u81f33\u670813\u65e5\uff0c\u7fa9\u5927\u5229\u7684\u6b7b\u4ea1\u7387\u78346.7\uff05\uff0c\u5168\u7403\u4e4b\u6700\uff01 \u5168\u7403\u570b\u5bb6\u8001\u5316\u7a0b\u5ea6\u6392\u540d\uff1a \u51a0\u8ecd\uff1a\u65e5\u672c27% \u4e9e\u8ecd\uff1a\u7fa9\u5927\u522923% \u5b63\u8ecd\uff1a\u5fb7\u570b21% \u6b64\u6b21\u6b66\u6f22\u75c5\u6bd2\u6b7b\u4ea1\u7387\uff1a \u7fa9\u5927\u5229\uff1a6.7% \u65e5\u672c\uff1a2.8% \u5fb7\u570b\uff1a0.2% \u90fd\u7a81\u986f\u7fa9\u5927\u5229\u7684\u9ad8\u6b7b\u4ea1\u7387\u4e0d\u5408\u7406\u3002 \u7f8e\u570b\u5a92\u9ad4\u300a\u83ef\u723e\u8857\u65e5\u5831\u300b\uff08Wall Street Journal\uff09\u5f15\u7576\u5730\u570b\u5bb6\u885b\u751f\u5c40\u7d71\u8a08\u6578\u64da\uff1a \u81f3\u4eca\u6b66\u80ba\u6b7b\u8005\u4e2d\uff0c 58%\u5e74\u9f61\u8d85\u904e80\u6b72\u3001 31%\u843d\u572870\u591a\u6b72\u3002 \u5e15\u591a\u74e6\u5927\u5b78\uff08University of Padua\uff09\u75c5\u6bd2\u5b78\u5bb6\u5e15\u9b6f\uff08Giorgio Pal\u00f9\uff09\u8aaa\uff1a\u300c\u751f\u7269\u5b78\u7684\u89d2\u5ea6\u7121\u6cd5\u89e3\u91cb\uff0c\u552f\u4e00\u80af\u5b9a\u7684\u662f\uff0c\u7fa9\u5927\u5229\u582a\u7a31\u5168\u4e16\u754c\u4eba\u53e3\u6700\u5e74\u8001\u7684\u570b\u5bb6\u4e4b\u4e00\u3002\u300d \u25cf Dr. Chen\uff1a https:\/\/zh.wikipedia.org\/wiki\/%E5%AE%89%E4%B8%9C%E5%B0%BC%C2%B7%E5%BC%97%E5%A5%91 \u5b89\u4e86\uff01\uff08\u5ddd\u666e\u8001\u4eba\u958b\u807d\u6bd4\u4ed6\u9084\u8001\u7684\u5b89\u6771\u5c3c.\u5f17\u5951\u5c08\u5bb6\uff09 \u9019\u500b\u6642\u5019\uff0c\u642c\u6f14\u548c\u4e8b\u4f6c\u7684\u9673\u540c\u5b78\u53c8\u51fa\u4f86\u6253\u5713\u5834\u4e86\uff0c\u5176\u5be6\u9673\u540c\u5b78\u624d\u662f\u771f\u6b63\u7684\u91ab\u5b78\u5c08\u5bb6\uff0c\u56e0\u70ba\u4ed6\u670d\u52d9\u7684\u516c\u53f8\u662f\u5168\u5e02\u6700\u5927\u91ab\u7642\u96c6\u5718BD\u516c\u53f8\u3002 \u25b2\u64da\u6d88\u606f\u4eba\u58eb\u7a31\uff0c\u6839\u64da\u7f8e\u570b\u60c5\u5831\u6a5f\u69cb\u7684\u60c5\u5831\u986f\u793a\uff0c\u4e2d\u5171\u9ad8\u5c64\u6b63\u6e96\u5099\u300c\u672b\u65e5\u9003\u96e3\u8a08\u756b\u300d\u3002\uff08\u5716\uff0fAdobe stock\uff09\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=38009\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u81fa\u7f8e\u8ad6\u6230\u3000\u7b46\u6230\u6642\u75ab - 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As chloroquine is not available in Korea, doctors could consider hydroxychloroquine 400mg orally per day, they said. There is no evidence that using lopinavir\/ritonavir with chloroquine is more effective than monotherapies, they added. In contrast, Chinese doctors recommend in their journal article to take chloroquine 500mg orally twice per day. \u25cf Dr. Robin\uff1a Based on clinicaltrials.gov info, Remdesivir studies are IV infusion of 40 mL in 3 hours, loading dose of 200mg and maintenance dose of 100mg for 4 or 9 days. Assuming efficacious, it is difficult to implement in pandemic situation. Wouldn't SC infusion be much easier to implement in a pandemic situation? I am hoping to look into this via BMGF for its PK, safety\/efficacy and tolerability. Will contact you privately. \u25cf Dr. Y-C,Hung\uff1a These are recommendations based on no evidence, something we call it expert opinion, the lowest level in evidence-based medicine. \u5982\u679c\u662f clinical trials \u7684\u4e00\u90e8\u5206\uff0c\u90a3\u662f\u53ef\u4ee5\u63a5\u53d7\u7684\uff0c\u4f46\u662f\u7528\u5728\u6240\u6709\u4eba\u662f\u9055\u53cd\u91ab\u5b78\u4e0a\u7684\u7b2c\u4e00\u539f\u5247\uff0cDo no harm. \u25cf Dr. Spencer\uff1a https:\/\/www.bbc.com\/news\/amp\/technology-51851292 Coronavirus: How can AI help fight the pandemic?  BBC \u25cf Dr. Spencer\uff1a https:\/\/cms.wj411.com\/portal\/index\/newshare_weibo.jsp?id=2217380&source=13 \u25cf \u5f90\u91ab\u5e2b\uff1a \u7fa9\u5927\u5229\u6b7b\u4ea1\u7387\u9ad8\u5f97\u96e2\u5947\uff01\u6bba\u4eba\u5147\u624b\u662f\u9023\u7e8c10\u5e74\u7684\u7dca\u7e2e\u653f\u7b56\uff01 \u622a\u81f33\u670813\u65e5\uff0c\u7fa9\u5927\u5229\u7684\u6b7b\u4ea1\u7387\u78346.7\uff05\uff0c\u5168\u7403\u4e4b\u6700\uff01 \u5168\u7403\u570b\u5bb6\u8001\u5316\u7a0b\u5ea6\u6392\u540d\uff1a \u51a0\u8ecd\uff1a\u65e5\u672c27% \u4e9e\u8ecd\uff1a\u7fa9\u5927\u522923% \u5b63\u8ecd\uff1a\u5fb7\u570b21% \u6b64\u6b21\u6b66\u6f22\u75c5\u6bd2\u6b7b\u4ea1\u7387\uff1a \u7fa9\u5927\u5229\uff1a6.7% \u65e5\u672c\uff1a2.8% \u5fb7\u570b\uff1a0.2% \u90fd\u7a81\u986f\u7fa9\u5927\u5229\u7684\u9ad8\u6b7b\u4ea1\u7387\u4e0d\u5408\u7406\u3002 \u7f8e\u570b\u5a92\u9ad4\u300a\u83ef\u723e\u8857\u65e5\u5831\u300b\uff08Wall Street Journal\uff09\u5f15\u7576\u5730\u570b\u5bb6\u885b\u751f\u5c40\u7d71\u8a08\u6578\u64da\uff1a \u81f3\u4eca\u6b66\u80ba\u6b7b\u8005\u4e2d\uff0c 58%\u5e74\u9f61\u8d85\u904e80\u6b72\u3001 31%\u843d\u572870\u591a\u6b72\u3002 \u5e15\u591a\u74e6\u5927\u5b78\uff08University of Padua\uff09\u75c5\u6bd2\u5b78\u5bb6\u5e15\u9b6f\uff08Giorgio Pal\u00f9\uff09\u8aaa\uff1a\u300c\u751f\u7269\u5b78\u7684\u89d2\u5ea6\u7121\u6cd5\u89e3\u91cb\uff0c\u552f\u4e00\u80af\u5b9a\u7684\u662f\uff0c\u7fa9\u5927\u5229\u582a\u7a31\u5168\u4e16\u754c\u4eba\u53e3\u6700\u5e74\u8001\u7684\u570b\u5bb6\u4e4b\u4e00\u3002\u300d \u25cf Dr. Chen\uff1a https:\/\/zh.wikipedia.org\/wiki\/%E5%AE%89%E4%B8%9C%E5%B0%BC%C2%B7%E5%BC%97%E5%A5%91 \u5b89\u4e86\uff01\uff08\u5ddd\u666e\u8001\u4eba\u958b\u807d\u6bd4\u4ed6\u9084\u8001\u7684\u5b89\u6771\u5c3c.\u5f17\u5951\u5c08\u5bb6\uff09 \u9019\u500b\u6642\u5019\uff0c\u642c\u6f14\u548c\u4e8b\u4f6c\u7684\u9673\u540c\u5b78\u53c8\u51fa\u4f86\u6253\u5713\u5834\u4e86\uff0c\u5176\u5be6\u9673\u540c\u5b78\u624d\u662f\u771f\u6b63\u7684\u91ab\u5b78\u5c08\u5bb6\uff0c\u56e0\u70ba\u4ed6\u670d\u52d9\u7684\u516c\u53f8\u662f\u5168\u5e02\u6700\u5927\u91ab\u7642\u96c6\u5718BD\u516c\u53f8\u3002 \u25b2\u64da\u6d88\u606f\u4eba\u58eb\u7a31\uff0c\u6839\u64da\u7f8e\u570b\u60c5\u5831\u6a5f\u69cb\u7684\u60c5\u5831\u986f\u793a\uff0c\u4e2d\u5171\u9ad8\u5c64\u6b63\u6e96\u5099\u300c\u672b\u65e5\u9003\u96e3\u8a08\u756b\u300d\u3002\uff08\u5716\uff0fAdobe stock\uff09\" \/>\n<meta property=\"og:url\" content=\"https:\/\/pingtungtimes.com.tw\/?p=38009\" \/>\n<meta property=\"og:site_name\" content=\"\u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/pingtungnews\" \/>\n<meta property=\"article:published_time\" content=\"2020-03-15T10:05:36+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-03-15T10:05:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/pingtungtimes.com.tw\/wp-content\/uploads\/2020\/03\/p2630792a639206072-ss.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1080\" \/>\n\t<meta property=\"og:image:height\" content=\"606\" \/>\n\t<meta property=\"og:image:type\" 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\u89ba\u5f97\u53ef\u4ee5\u8f49\u8ff0\u7d66\u76f8\u95dc\u4eba\u54e1\u53c3\u8003\uff0c\u4f46\u5176\u7576\u4e8b\u4eba\u7684\u540d\u7a31\u90fd\u5df2\u8b8a\u9020\uff1a \u525b\u525b\u5f15\u767c\u7684\u4e00\u5834\u6d89\u53ca\u5169\u5cb8\u653f\u6cbb\u7684\u201c\u75ab\u60c5\u771f\u5047\u201d\u7684\u8faf\u8ad6\uff0c\u7531\u672c\u73ed\u7684\u9673\u540c\u5b78\u4ee5\u4e0b\u9762\u7684\u4e00\u6bb5\u8a71\u66ab\u6642\u4f86\u6b62\u606f\u6230\u706b\uff0c\u4e26\u91cd\u65b0\u9ede\u71c3\u53e6\u4e00\u5834\u91ab\u7642\u65b9\u6cd5\u7684\u6230\u706b\uff1a \u25cf Dr. Chen\uff1a \u5728\u7f8e\u770b\u83ef\u8a9e\u96fb\u8996, \u5927\u9678\u65b0\u805e\u5831\u5c0e\u7684\u7f8e\u570b\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1, \u53f0\u7063\u65b0\u805e\u5831\u5c0e\u7684\u5927\u9678\u65b0\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1. \u25cf Dr. Spencer\uff1a \u4ee5\u76ee\u524d\u5728\u6aa2\u6e2c\u4e0d\u8db3\u548c\u5df2\u78ba\u75b9\u75c5\u4eba\u7684\u5206\u4f48\u60c5\u6cc1\u4f86\u770b\uff0c\u7f8e\u570b\u75ab\u60c5\u7206\u767c\u662f\u7121\u53ef\u907f\u514d\u3002\u75ab\u60c5\u7206\u767c\u5f8c ICU \u76ee\u524d\u7684\u5e8a\u4f4d\u4e0d\u8db3\uff0c\u547c\u5438\u673a\u4e0d\u5920\uff0c\u9019\u90fd\u6703\u662f\u554f\u984c\u3002Lombardy, Italy \u662f\u6b50\u6d32\u533b\u7642\u6700\u5148\u9032\u7684\u5340\u57df\u4e4b\u4e00\uff0c\u770b\u770b\u4ed6\u5011\u73fe\u5728\u533b\u7642\u80fd\u529b\u9060\u9060\u900f\u652f\u7684\u6158\u72c0\u3002 \u25cf Dr. Y-C,Hung\uff1a \u554f\u984c\u662f\u6240\u4f7f\u7528\u7684\u5291\u91cf\u6709\u7121\u6b64\u6548\u7528\uff0c\u548c\u4ec0\u9ebc\u6642\u5019\u7528\u3002\u7406\u8ad6\u4e0a\u9019\u61c9\u8a72\u5f88\u65e9\u7528\uff0c\u7528\u5728\u4ec0\u9ebc\u6a23\u7684\u4eba\u3002\u591a\u6578\u4eba\u75c7\u72c0\u90fd\u5f88\u8efd\uff0c\u6240\u4ee5\u5373\u4f7f\u4e0d\u6cbb\u7642\u4e5f\u6703\u597d\u3002\u5728\u9019\u7a2e\u60c5\u6cc1\u4e0b\uff0c\u4f7f chloroquin \u6216\u662f\u5176\u4ed6\u85e5\u5373\u4f7f\u4ed6\u5011\u526f\u4f5c\u7528\u4e0d\u5927\u5728\u91ab\u5b78\u4e0a\u662f risk \u5927\u65bc benefit. \u5f88\u591a\u5728 in vitro \u7528\u7684\u5291\u91cf\u548c\u6fc3\u5ea6\u662f\u7d66\u4eba\u9ad4\u4f7f\u7528\u7684\u6642\u5019\u9054\u4e0d\u5230\u7684\u3002 \u7528\u5728\u6cbb\u7642\u7627\u75be\u4e0d\u540c\uff0c\u56e0\u70ba\u539f\u87f2\u5728\u7d05\u8840\u7403\u5167\uff0c chloroquin \u7684\u6fc3\u5ea6\u6bd4\u8f03\u5bb9\u6613\u9054\u5230\u3002corona virus \u662f\u5f71\u97ff\u80ba\u90e8\u8868\u76ae\u7d30\u80de\uff0c\u85e5\u5fc5\u9808\u5f9e\u5e95\u90e8\u7684\u8840\u7ba1\u6ef2\u900f\u9032\u4f86\uff0c\u6240\u4ee5\u53ef\u80fd\u9700\u8981\u5f88\u9ad8\u5291\u91cf\u624d\u80fd\u9054\u5230 in vitro \u7684\u6fc3\u5ea6\u3002\u5728\u505a\u7d30\u80de\u5be6\u9a57\u6642\uff0c\u85e5\u90fd\u662f\u76f4\u63a5\u653e\u5728\u7d30\u80de\u7684\u8868\u9762\u3002 \u25cf Dr. Spencer\uff1a In the journal from Korea: Quote: For the antiviral treatment, the doctors recommended lopinavir 400mg\\\/ritonavir 100mg (Kaletra two tablets, twice a day) or chloroquine 500mg orally per day. As chloroquine is not available in Korea, doctors could consider hydroxychloroquine 400mg orally per day, they said. There is no evidence that using lopinavir\\\/ritonavir with chloroquine is more effective than monotherapies, they added. In contrast, Chinese doctors recommend in their journal article to take chloroquine 500mg orally twice per day. \u25cf Dr. Robin\uff1a Based on clinicaltrials.gov info, Remdesivir studies are IV infusion of 40 mL in 3 hours, loading dose of 200mg and maintenance dose of 100mg for 4 or 9 days. Assuming efficacious, it is difficult to implement in pandemic situation. Wouldn't SC infusion be much easier to implement in a pandemic situation? I am hoping to look into this via BMGF for its PK, safety\\\/efficacy and tolerability. Will contact you privately. \u25cf Dr. Y-C,Hung\uff1a These are recommendations based on no evidence, something we call it expert opinion, the lowest level in evidence-based medicine. \u5982\u679c\u662f clinical trials \u7684\u4e00\u90e8\u5206\uff0c\u90a3\u662f\u53ef\u4ee5\u63a5\u53d7\u7684\uff0c\u4f46\u662f\u7528\u5728\u6240\u6709\u4eba\u662f\u9055\u53cd\u91ab\u5b78\u4e0a\u7684\u7b2c\u4e00\u539f\u5247\uff0cDo no harm. \u25cf Dr. Spencer\uff1a https:\\\/\\\/www.bbc.com\\\/news\\\/amp\\\/technology-51851292 Coronavirus: How can AI help fight the pandemic?  BBC \u25cf Dr. Spencer\uff1a https:\\\/\\\/cms.wj411.com\\\/portal\\\/index\\\/newshare_weibo.jsp?id=2217380&source=13 \u25cf \u5f90\u91ab\u5e2b\uff1a \u7fa9\u5927\u5229\u6b7b\u4ea1\u7387\u9ad8\u5f97\u96e2\u5947\uff01\u6bba\u4eba\u5147\u624b\u662f\u9023\u7e8c10\u5e74\u7684\u7dca\u7e2e\u653f\u7b56\uff01 \u622a\u81f33\u670813\u65e5\uff0c\u7fa9\u5927\u5229\u7684\u6b7b\u4ea1\u7387\u78346.7\uff05\uff0c\u5168\u7403\u4e4b\u6700\uff01 \u5168\u7403\u570b\u5bb6\u8001\u5316\u7a0b\u5ea6\u6392\u540d\uff1a \u51a0\u8ecd\uff1a\u65e5\u672c27% \u4e9e\u8ecd\uff1a\u7fa9\u5927\u522923% \u5b63\u8ecd\uff1a\u5fb7\u570b21% \u6b64\u6b21\u6b66\u6f22\u75c5\u6bd2\u6b7b\u4ea1\u7387\uff1a \u7fa9\u5927\u5229\uff1a6.7% \u65e5\u672c\uff1a2.8% \u5fb7\u570b\uff1a0.2% \u90fd\u7a81\u986f\u7fa9\u5927\u5229\u7684\u9ad8\u6b7b\u4ea1\u7387\u4e0d\u5408\u7406\u3002 \u7f8e\u570b\u5a92\u9ad4\u300a\u83ef\u723e\u8857\u65e5\u5831\u300b\uff08Wall Street Journal\uff09\u5f15\u7576\u5730\u570b\u5bb6\u885b\u751f\u5c40\u7d71\u8a08\u6578\u64da\uff1a \u81f3\u4eca\u6b66\u80ba\u6b7b\u8005\u4e2d\uff0c 58%\u5e74\u9f61\u8d85\u904e80\u6b72\u3001 31%\u843d\u572870\u591a\u6b72\u3002 \u5e15\u591a\u74e6\u5927\u5b78\uff08University of Padua\uff09\u75c5\u6bd2\u5b78\u5bb6\u5e15\u9b6f\uff08Giorgio Pal\u00f9\uff09\u8aaa\uff1a\u300c\u751f\u7269\u5b78\u7684\u89d2\u5ea6\u7121\u6cd5\u89e3\u91cb\uff0c\u552f\u4e00\u80af\u5b9a\u7684\u662f\uff0c\u7fa9\u5927\u5229\u582a\u7a31\u5168\u4e16\u754c\u4eba\u53e3\u6700\u5e74\u8001\u7684\u570b\u5bb6\u4e4b\u4e00\u3002\u300d \u25cf Dr. Chen\uff1a https:\\\/\\\/zh.wikipedia.org\\\/wiki\\\/%E5%AE%89%E4%B8%9C%E5%B0%BC%C2%B7%E5%BC%97%E5%A5%91 \u5b89\u4e86\uff01\uff08\u5ddd\u666e\u8001\u4eba\u958b\u807d\u6bd4\u4ed6\u9084\u8001\u7684\u5b89\u6771\u5c3c.\u5f17\u5951\u5c08\u5bb6\uff09 \u9019\u500b\u6642\u5019\uff0c\u642c\u6f14\u548c\u4e8b\u4f6c\u7684\u9673\u540c\u5b78\u53c8\u51fa\u4f86\u6253\u5713\u5834\u4e86\uff0c\u5176\u5be6\u9673\u540c\u5b78\u624d\u662f\u771f\u6b63\u7684\u91ab\u5b78\u5c08\u5bb6\uff0c\u56e0\u70ba\u4ed6\u670d\u52d9\u7684\u516c\u53f8\u662f\u5168\u5e02\u6700\u5927\u91ab\u7642\u96c6\u5718BD\u516c\u53f8\u3002 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\u525b\u525b\u5f15\u767c\u7684\u4e00\u5834\u6d89\u53ca\u5169\u5cb8\u653f\u6cbb\u7684\u201c\u75ab\u60c5\u771f\u5047\u201d\u7684\u8faf\u8ad6\uff0c\u7531\u672c\u73ed\u7684\u9673\u540c\u5b78\u4ee5\u4e0b\u9762\u7684\u4e00\u6bb5\u8a71\u66ab\u6642\u4f86\u6b62\u606f\u6230\u706b\uff0c\u4e26\u91cd\u65b0\u9ede\u71c3\u53e6\u4e00\u5834\u91ab\u7642\u65b9\u6cd5\u7684\u6230\u706b\uff1a \u25cf Dr. Chen\uff1a \u5728\u7f8e\u770b\u83ef\u8a9e\u96fb\u8996, \u5927\u9678\u65b0\u805e\u5831\u5c0e\u7684\u7f8e\u570b\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1, \u53f0\u7063\u65b0\u805e\u5831\u5c0e\u7684\u5927\u9678\u65b0\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1. \u25cf Dr. Spencer\uff1a \u4ee5\u76ee\u524d\u5728\u6aa2\u6e2c\u4e0d\u8db3\u548c\u5df2\u78ba\u75b9\u75c5\u4eba\u7684\u5206\u4f48\u60c5\u6cc1\u4f86\u770b\uff0c\u7f8e\u570b\u75ab\u60c5\u7206\u767c\u662f\u7121\u53ef\u907f\u514d\u3002\u75ab\u60c5\u7206\u767c\u5f8c ICU \u76ee\u524d\u7684\u5e8a\u4f4d\u4e0d\u8db3\uff0c\u547c\u5438\u673a\u4e0d\u5920\uff0c\u9019\u90fd\u6703\u662f\u554f\u984c\u3002Lombardy, Italy \u662f\u6b50\u6d32\u533b\u7642\u6700\u5148\u9032\u7684\u5340\u57df\u4e4b\u4e00\uff0c\u770b\u770b\u4ed6\u5011\u73fe\u5728\u533b\u7642\u80fd\u529b\u9060\u9060\u900f\u652f\u7684\u6158\u72c0\u3002 \u25cf Dr. Y-C,Hung\uff1a \u554f\u984c\u662f\u6240\u4f7f\u7528\u7684\u5291\u91cf\u6709\u7121\u6b64\u6548\u7528\uff0c\u548c\u4ec0\u9ebc\u6642\u5019\u7528\u3002\u7406\u8ad6\u4e0a\u9019\u61c9\u8a72\u5f88\u65e9\u7528\uff0c\u7528\u5728\u4ec0\u9ebc\u6a23\u7684\u4eba\u3002\u591a\u6578\u4eba\u75c7\u72c0\u90fd\u5f88\u8efd\uff0c\u6240\u4ee5\u5373\u4f7f\u4e0d\u6cbb\u7642\u4e5f\u6703\u597d\u3002\u5728\u9019\u7a2e\u60c5\u6cc1\u4e0b\uff0c\u4f7f chloroquin \u6216\u662f\u5176\u4ed6\u85e5\u5373\u4f7f\u4ed6\u5011\u526f\u4f5c\u7528\u4e0d\u5927\u5728\u91ab\u5b78\u4e0a\u662f risk \u5927\u65bc benefit. \u5f88\u591a\u5728 in vitro \u7528\u7684\u5291\u91cf\u548c\u6fc3\u5ea6\u662f\u7d66\u4eba\u9ad4\u4f7f\u7528\u7684\u6642\u5019\u9054\u4e0d\u5230\u7684\u3002 \u7528\u5728\u6cbb\u7642\u7627\u75be\u4e0d\u540c\uff0c\u56e0\u70ba\u539f\u87f2\u5728\u7d05\u8840\u7403\u5167\uff0c chloroquin \u7684\u6fc3\u5ea6\u6bd4\u8f03\u5bb9\u6613\u9054\u5230\u3002corona virus \u662f\u5f71\u97ff\u80ba\u90e8\u8868\u76ae\u7d30\u80de\uff0c\u85e5\u5fc5\u9808\u5f9e\u5e95\u90e8\u7684\u8840\u7ba1\u6ef2\u900f\u9032\u4f86\uff0c\u6240\u4ee5\u53ef\u80fd\u9700\u8981\u5f88\u9ad8\u5291\u91cf\u624d\u80fd\u9054\u5230 in vitro \u7684\u6fc3\u5ea6\u3002\u5728\u505a\u7d30\u80de\u5be6\u9a57\u6642\uff0c\u85e5\u90fd\u662f\u76f4\u63a5\u653e\u5728\u7d30\u80de\u7684\u8868\u9762\u3002 \u25cf Dr. Spencer\uff1a In the journal from Korea: Quote: For the antiviral treatment, the doctors recommended lopinavir 400mg\/ritonavir 100mg (Kaletra two tablets, twice a day) or chloroquine 500mg orally per day. As chloroquine is not available in Korea, doctors could consider hydroxychloroquine 400mg orally per day, they said. There is no evidence that using lopinavir\/ritonavir with chloroquine is more effective than monotherapies, they added. In contrast, Chinese doctors recommend in their journal article to take chloroquine 500mg orally twice per day. \u25cf Dr. Robin\uff1a Based on clinicaltrials.gov info, Remdesivir studies are IV infusion of 40 mL in 3 hours, loading dose of 200mg and maintenance dose of 100mg for 4 or 9 days. Assuming efficacious, it is difficult to implement in pandemic situation. Wouldn't SC infusion be much easier to implement in a pandemic situation? I am hoping to look into this via BMGF for its PK, safety\/efficacy and tolerability. Will contact you privately. \u25cf Dr. Y-C,Hung\uff1a These are recommendations based on no evidence, something we call it expert opinion, the lowest level in evidence-based medicine. \u5982\u679c\u662f clinical trials \u7684\u4e00\u90e8\u5206\uff0c\u90a3\u662f\u53ef\u4ee5\u63a5\u53d7\u7684\uff0c\u4f46\u662f\u7528\u5728\u6240\u6709\u4eba\u662f\u9055\u53cd\u91ab\u5b78\u4e0a\u7684\u7b2c\u4e00\u539f\u5247\uff0cDo no harm. \u25cf Dr. Spencer\uff1a https:\/\/www.bbc.com\/news\/amp\/technology-51851292 Coronavirus: How can AI help fight the pandemic?  BBC \u25cf Dr. Spencer\uff1a https:\/\/cms.wj411.com\/portal\/index\/newshare_weibo.jsp?id=2217380&source=13 \u25cf \u5f90\u91ab\u5e2b\uff1a \u7fa9\u5927\u5229\u6b7b\u4ea1\u7387\u9ad8\u5f97\u96e2\u5947\uff01\u6bba\u4eba\u5147\u624b\u662f\u9023\u7e8c10\u5e74\u7684\u7dca\u7e2e\u653f\u7b56\uff01 \u622a\u81f33\u670813\u65e5\uff0c\u7fa9\u5927\u5229\u7684\u6b7b\u4ea1\u7387\u78346.7\uff05\uff0c\u5168\u7403\u4e4b\u6700\uff01 \u5168\u7403\u570b\u5bb6\u8001\u5316\u7a0b\u5ea6\u6392\u540d\uff1a \u51a0\u8ecd\uff1a\u65e5\u672c27% \u4e9e\u8ecd\uff1a\u7fa9\u5927\u522923% \u5b63\u8ecd\uff1a\u5fb7\u570b21% \u6b64\u6b21\u6b66\u6f22\u75c5\u6bd2\u6b7b\u4ea1\u7387\uff1a \u7fa9\u5927\u5229\uff1a6.7% \u65e5\u672c\uff1a2.8% \u5fb7\u570b\uff1a0.2% \u90fd\u7a81\u986f\u7fa9\u5927\u5229\u7684\u9ad8\u6b7b\u4ea1\u7387\u4e0d\u5408\u7406\u3002 \u7f8e\u570b\u5a92\u9ad4\u300a\u83ef\u723e\u8857\u65e5\u5831\u300b\uff08Wall Street Journal\uff09\u5f15\u7576\u5730\u570b\u5bb6\u885b\u751f\u5c40\u7d71\u8a08\u6578\u64da\uff1a \u81f3\u4eca\u6b66\u80ba\u6b7b\u8005\u4e2d\uff0c 58%\u5e74\u9f61\u8d85\u904e80\u6b72\u3001 31%\u843d\u572870\u591a\u6b72\u3002 \u5e15\u591a\u74e6\u5927\u5b78\uff08University of Padua\uff09\u75c5\u6bd2\u5b78\u5bb6\u5e15\u9b6f\uff08Giorgio Pal\u00f9\uff09\u8aaa\uff1a\u300c\u751f\u7269\u5b78\u7684\u89d2\u5ea6\u7121\u6cd5\u89e3\u91cb\uff0c\u552f\u4e00\u80af\u5b9a\u7684\u662f\uff0c\u7fa9\u5927\u5229\u582a\u7a31\u5168\u4e16\u754c\u4eba\u53e3\u6700\u5e74\u8001\u7684\u570b\u5bb6\u4e4b\u4e00\u3002\u300d \u25cf Dr. Chen\uff1a https:\/\/zh.wikipedia.org\/wiki\/%E5%AE%89%E4%B8%9C%E5%B0%BC%C2%B7%E5%BC%97%E5%A5%91 \u5b89\u4e86\uff01\uff08\u5ddd\u666e\u8001\u4eba\u958b\u807d\u6bd4\u4ed6\u9084\u8001\u7684\u5b89\u6771\u5c3c.\u5f17\u5951\u5c08\u5bb6\uff09 \u9019\u500b\u6642\u5019\uff0c\u642c\u6f14\u548c\u4e8b\u4f6c\u7684\u9673\u540c\u5b78\u53c8\u51fa\u4f86\u6253\u5713\u5834\u4e86\uff0c\u5176\u5be6\u9673\u540c\u5b78\u624d\u662f\u771f\u6b63\u7684\u91ab\u5b78\u5c08\u5bb6\uff0c\u56e0\u70ba\u4ed6\u670d\u52d9\u7684\u516c\u53f8\u662f\u5168\u5e02\u6700\u5927\u91ab\u7642\u96c6\u5718BD\u516c\u53f8\u3002 \u25b2\u64da\u6d88\u606f\u4eba\u58eb\u7a31\uff0c\u6839\u64da\u7f8e\u570b\u60c5\u5831\u6a5f\u69cb\u7684\u60c5\u5831\u986f\u793a\uff0c\u4e2d\u5171\u9ad8\u5c64\u6b63\u6e96\u5099\u300c\u672b\u65e5\u9003\u96e3\u8a08\u756b\u300d\u3002\uff08\u5716\uff0fAdobe stock\uff09","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pingtungtimes.com.tw\/?p=38009","og_locale":"zh_TW","og_type":"article","og_title":"\u81fa\u7f8e\u8ad6\u6230\u3000\u7b46\u6230\u6642\u75ab - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","og_description":"\u3010\u674e\u91cd\u5fb7\uff0f\u5c08\u6b04\u5831\u5c0e2020\/3\/14\u3011\u3000\u91cd\u5fb7 \u56e0\u70ba\u653f\u6cbb\u7acb\u5834\u56e0\u7d20\u800c\u5728\u201c\u81fa\u5357\u4e00\u4e2d1976\u201d\u7fa4\u7d44\u4e2d\u81ea\u6211\u7981\u8a00\uff0c\u8a72\u7fa4\u7d44156\u4eba\u5927\u591a\u662f\u8207 \u91cd\u5fb7 \u540c\u5c46\u7684\u540c\u5b78\uff0c\u4f46\u662f\u591a\u6578\u662f\u535a\u58eb\uff0c\u91ab\u751f\u7279\u5225\u591a\uff0c\u4e5f\u6709\u7d04\u4e09\u5206\u4e4b\u4e00\u662f\u65c5\u5c45\u7f8e\u570b\u3002 \u7531\u65bc\u90fd\u662f\u83c1\u82f1\u4efd\u5b50\uff0c\u56e0\u6b64\u8ab0\u4e5f\u4e0d\u670d\u8ab0\uff0c\u5c24\u5176\u6975\u5c11\u7684\u4e00\u4e8c\u4f4d\u653f\u6cbb\u7acb\u5834\u50be\u4e2d\u7684\u4eba\u58eb\u7e3d\u6703\u5728\u7fa4\u7d44\u4e2d\u6311\u6230\u540c\u5b78\u7684\u601d\u60f3\u908f\u8f2f\uff0c\u70ba\u5176\u8a8d\u77e5\u7684\u7956\u570b\u8faf\u8b77\uff0c\u56e0\u6b64 \u91cd\u5fb7 \u8207\u5176\u4ed6\u8a31\u591a\u5177\u6709\u516c\u773e\u4eba\u7269\u8eab\u5206\u7684\u540c\u5b78\u66f4\u662f\u4e0d\u9858\u610f\u767c\u8868\u4efb\u4f55\u610f\u898b\uff0c\u4ee5\u514d\u6372\u5165\u7121\u8b02\u7684\u8ad6\u6230\u4e4b\u4e2d\u3002 \u4f46\u662f\u4ee5\u4e0b\u7684\u4e00\u500b\u6709\u95dc\u91ab\u5b78\u7684\u8ad6\u6230\uff0c\u91cd\u5fb7 \u89ba\u5f97\u53ef\u4ee5\u8f49\u8ff0\u7d66\u76f8\u95dc\u4eba\u54e1\u53c3\u8003\uff0c\u4f46\u5176\u7576\u4e8b\u4eba\u7684\u540d\u7a31\u90fd\u5df2\u8b8a\u9020\uff1a \u525b\u525b\u5f15\u767c\u7684\u4e00\u5834\u6d89\u53ca\u5169\u5cb8\u653f\u6cbb\u7684\u201c\u75ab\u60c5\u771f\u5047\u201d\u7684\u8faf\u8ad6\uff0c\u7531\u672c\u73ed\u7684\u9673\u540c\u5b78\u4ee5\u4e0b\u9762\u7684\u4e00\u6bb5\u8a71\u66ab\u6642\u4f86\u6b62\u606f\u6230\u706b\uff0c\u4e26\u91cd\u65b0\u9ede\u71c3\u53e6\u4e00\u5834\u91ab\u7642\u65b9\u6cd5\u7684\u6230\u706b\uff1a \u25cf Dr. Chen\uff1a \u5728\u7f8e\u770b\u83ef\u8a9e\u96fb\u8996, \u5927\u9678\u65b0\u805e\u5831\u5c0e\u7684\u7f8e\u570b\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1, \u53f0\u7063\u65b0\u805e\u5831\u5c0e\u7684\u5927\u9678\u65b0\u75ab\u60c5\u6bd4\u8f03\u53ef\u4fe1. \u25cf Dr. Spencer\uff1a \u4ee5\u76ee\u524d\u5728\u6aa2\u6e2c\u4e0d\u8db3\u548c\u5df2\u78ba\u75b9\u75c5\u4eba\u7684\u5206\u4f48\u60c5\u6cc1\u4f86\u770b\uff0c\u7f8e\u570b\u75ab\u60c5\u7206\u767c\u662f\u7121\u53ef\u907f\u514d\u3002\u75ab\u60c5\u7206\u767c\u5f8c ICU \u76ee\u524d\u7684\u5e8a\u4f4d\u4e0d\u8db3\uff0c\u547c\u5438\u673a\u4e0d\u5920\uff0c\u9019\u90fd\u6703\u662f\u554f\u984c\u3002Lombardy, Italy \u662f\u6b50\u6d32\u533b\u7642\u6700\u5148\u9032\u7684\u5340\u57df\u4e4b\u4e00\uff0c\u770b\u770b\u4ed6\u5011\u73fe\u5728\u533b\u7642\u80fd\u529b\u9060\u9060\u900f\u652f\u7684\u6158\u72c0\u3002 \u25cf Dr. Y-C,Hung\uff1a \u554f\u984c\u662f\u6240\u4f7f\u7528\u7684\u5291\u91cf\u6709\u7121\u6b64\u6548\u7528\uff0c\u548c\u4ec0\u9ebc\u6642\u5019\u7528\u3002\u7406\u8ad6\u4e0a\u9019\u61c9\u8a72\u5f88\u65e9\u7528\uff0c\u7528\u5728\u4ec0\u9ebc\u6a23\u7684\u4eba\u3002\u591a\u6578\u4eba\u75c7\u72c0\u90fd\u5f88\u8efd\uff0c\u6240\u4ee5\u5373\u4f7f\u4e0d\u6cbb\u7642\u4e5f\u6703\u597d\u3002\u5728\u9019\u7a2e\u60c5\u6cc1\u4e0b\uff0c\u4f7f chloroquin \u6216\u662f\u5176\u4ed6\u85e5\u5373\u4f7f\u4ed6\u5011\u526f\u4f5c\u7528\u4e0d\u5927\u5728\u91ab\u5b78\u4e0a\u662f risk \u5927\u65bc benefit. \u5f88\u591a\u5728 in vitro \u7528\u7684\u5291\u91cf\u548c\u6fc3\u5ea6\u662f\u7d66\u4eba\u9ad4\u4f7f\u7528\u7684\u6642\u5019\u9054\u4e0d\u5230\u7684\u3002 \u7528\u5728\u6cbb\u7642\u7627\u75be\u4e0d\u540c\uff0c\u56e0\u70ba\u539f\u87f2\u5728\u7d05\u8840\u7403\u5167\uff0c chloroquin \u7684\u6fc3\u5ea6\u6bd4\u8f03\u5bb9\u6613\u9054\u5230\u3002corona virus \u662f\u5f71\u97ff\u80ba\u90e8\u8868\u76ae\u7d30\u80de\uff0c\u85e5\u5fc5\u9808\u5f9e\u5e95\u90e8\u7684\u8840\u7ba1\u6ef2\u900f\u9032\u4f86\uff0c\u6240\u4ee5\u53ef\u80fd\u9700\u8981\u5f88\u9ad8\u5291\u91cf\u624d\u80fd\u9054\u5230 in vitro \u7684\u6fc3\u5ea6\u3002\u5728\u505a\u7d30\u80de\u5be6\u9a57\u6642\uff0c\u85e5\u90fd\u662f\u76f4\u63a5\u653e\u5728\u7d30\u80de\u7684\u8868\u9762\u3002 \u25cf Dr. Spencer\uff1a In the journal from Korea: Quote: For the antiviral treatment, the doctors recommended lopinavir 400mg\/ritonavir 100mg (Kaletra two tablets, twice a day) or chloroquine 500mg orally per day. As chloroquine is not available in Korea, doctors could consider hydroxychloroquine 400mg orally per day, they said. There is no evidence that using lopinavir\/ritonavir with chloroquine is more effective than monotherapies, they added. In contrast, Chinese doctors recommend in their journal article to take chloroquine 500mg orally twice per day. \u25cf Dr. Robin\uff1a Based on clinicaltrials.gov info, Remdesivir studies are IV infusion of 40 mL in 3 hours, loading dose of 200mg and maintenance dose of 100mg for 4 or 9 days. Assuming efficacious, it is difficult to implement in pandemic situation. Wouldn't SC infusion be much easier to implement in a pandemic situation? I am hoping to look into this via BMGF for its PK, safety\/efficacy and tolerability. Will contact you privately. \u25cf Dr. Y-C,Hung\uff1a These are recommendations based on no evidence, something we call it expert opinion, the lowest level in evidence-based medicine. \u5982\u679c\u662f clinical trials \u7684\u4e00\u90e8\u5206\uff0c\u90a3\u662f\u53ef\u4ee5\u63a5\u53d7\u7684\uff0c\u4f46\u662f\u7528\u5728\u6240\u6709\u4eba\u662f\u9055\u53cd\u91ab\u5b78\u4e0a\u7684\u7b2c\u4e00\u539f\u5247\uff0cDo no harm. \u25cf Dr. Spencer\uff1a https:\/\/www.bbc.com\/news\/amp\/technology-51851292 Coronavirus: How can AI help fight the pandemic?  BBC \u25cf Dr. Spencer\uff1a https:\/\/cms.wj411.com\/portal\/index\/newshare_weibo.jsp?id=2217380&source=13 \u25cf \u5f90\u91ab\u5e2b\uff1a \u7fa9\u5927\u5229\u6b7b\u4ea1\u7387\u9ad8\u5f97\u96e2\u5947\uff01\u6bba\u4eba\u5147\u624b\u662f\u9023\u7e8c10\u5e74\u7684\u7dca\u7e2e\u653f\u7b56\uff01 \u622a\u81f33\u670813\u65e5\uff0c\u7fa9\u5927\u5229\u7684\u6b7b\u4ea1\u7387\u78346.7\uff05\uff0c\u5168\u7403\u4e4b\u6700\uff01 \u5168\u7403\u570b\u5bb6\u8001\u5316\u7a0b\u5ea6\u6392\u540d\uff1a \u51a0\u8ecd\uff1a\u65e5\u672c27% \u4e9e\u8ecd\uff1a\u7fa9\u5927\u522923% \u5b63\u8ecd\uff1a\u5fb7\u570b21% \u6b64\u6b21\u6b66\u6f22\u75c5\u6bd2\u6b7b\u4ea1\u7387\uff1a \u7fa9\u5927\u5229\uff1a6.7% \u65e5\u672c\uff1a2.8% \u5fb7\u570b\uff1a0.2% \u90fd\u7a81\u986f\u7fa9\u5927\u5229\u7684\u9ad8\u6b7b\u4ea1\u7387\u4e0d\u5408\u7406\u3002 \u7f8e\u570b\u5a92\u9ad4\u300a\u83ef\u723e\u8857\u65e5\u5831\u300b\uff08Wall Street Journal\uff09\u5f15\u7576\u5730\u570b\u5bb6\u885b\u751f\u5c40\u7d71\u8a08\u6578\u64da\uff1a \u81f3\u4eca\u6b66\u80ba\u6b7b\u8005\u4e2d\uff0c 58%\u5e74\u9f61\u8d85\u904e80\u6b72\u3001 31%\u843d\u572870\u591a\u6b72\u3002 \u5e15\u591a\u74e6\u5927\u5b78\uff08University of Padua\uff09\u75c5\u6bd2\u5b78\u5bb6\u5e15\u9b6f\uff08Giorgio Pal\u00f9\uff09\u8aaa\uff1a\u300c\u751f\u7269\u5b78\u7684\u89d2\u5ea6\u7121\u6cd5\u89e3\u91cb\uff0c\u552f\u4e00\u80af\u5b9a\u7684\u662f\uff0c\u7fa9\u5927\u5229\u582a\u7a31\u5168\u4e16\u754c\u4eba\u53e3\u6700\u5e74\u8001\u7684\u570b\u5bb6\u4e4b\u4e00\u3002\u300d \u25cf Dr. Chen\uff1a https:\/\/zh.wikipedia.org\/wiki\/%E5%AE%89%E4%B8%9C%E5%B0%BC%C2%B7%E5%BC%97%E5%A5%91 \u5b89\u4e86\uff01\uff08\u5ddd\u666e\u8001\u4eba\u958b\u807d\u6bd4\u4ed6\u9084\u8001\u7684\u5b89\u6771\u5c3c.\u5f17\u5951\u5c08\u5bb6\uff09 \u9019\u500b\u6642\u5019\uff0c\u642c\u6f14\u548c\u4e8b\u4f6c\u7684\u9673\u540c\u5b78\u53c8\u51fa\u4f86\u6253\u5713\u5834\u4e86\uff0c\u5176\u5be6\u9673\u540c\u5b78\u624d\u662f\u771f\u6b63\u7684\u91ab\u5b78\u5c08\u5bb6\uff0c\u56e0\u70ba\u4ed6\u670d\u52d9\u7684\u516c\u53f8\u662f\u5168\u5e02\u6700\u5927\u91ab\u7642\u96c6\u5718BD\u516c\u53f8\u3002 \u25b2\u64da\u6d88\u606f\u4eba\u58eb\u7a31\uff0c\u6839\u64da\u7f8e\u570b\u60c5\u5831\u6a5f\u69cb\u7684\u60c5\u5831\u986f\u793a\uff0c\u4e2d\u5171\u9ad8\u5c64\u6b63\u6e96\u5099\u300c\u672b\u65e5\u9003\u96e3\u8a08\u756b\u300d\u3002\uff08\u5716\uff0fAdobe stock\uff09","og_url":"https:\/\/pingtungtimes.com.tw\/?p=38009","og_site_name":"\u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","article_publisher":"https:\/\/www.facebook.com\/pingtungnews","article_published_time":"2020-03-15T10:05:36+00:00","article_modified_time":"2020-03-15T10:05:41+00:00","og_image":[{"width":1080,"height":606,"url":"https:\/\/pingtungtimes.com.tw\/wp-content\/uploads\/2020\/03\/p2630792a639206072-ss.jpg","type":"image\/jpeg"}],"author":"fanjiang","twitter_card":"summary_large_image","twitter_misc":{"\u4f5c\u8005:":"fanjiang","\u9810\u4f30\u95b1\u8b80\u6642\u9593":"1 \u5206\u9418"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"NewsArticle","@id":"https:\/\/pingtungtimes.com.tw\/?p=38009#article","isPartOf":{"@id":"https:\/\/pingtungtimes.com.tw\/?p=38009"},"author":{"name":"fanjiang","@id":"https:\/\/pingtungtimes.com.tw\/#\/schema\/person\/90cf880d4d210d8db447ae0199435aa4"},"headline":"\u81fa\u7f8e\u8ad6\u6230\u3000\u7b46\u6230\u6642\u75ab","datePublished":"2020-03-15T10:05:36+00:00","dateModified":"2020-03-15T10:05:41+00:00","mainEntityOfPage":{"@id":"https:\/\/pingtungtimes.com.tw\/?p=38009"},"wordCount":265,"commentCount":2,"publisher":{"@id":"https:\/\/pingtungtimes.com.tw\/#organization"},"image":{"@id":"https:\/\/pingtungtimes.com.tw\/?p=38009#primaryimage"},"thumbnailUrl":"https:\/\/pingtungtimes.com.tw\/wp-content\/uploads\/2020\/03\/p2630792a639206072-ss.jpg","keywords":["\u6230\u706b","\u75ab\u60c5\u771f\u5047","\u8faf\u8ad6","\u91ab\u7642\u65b9\u6cd5"],"articleSection":["\u9577\u7167\u5c08\u6b04"],"inLanguage":"zh-TW","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/pingtungtimes.com.tw\/?p=38009#respond"]}]},{"@type":"WebPage","@id":"https:\/\/pingtungtimes.com.tw\/?p=38009","url":"https:\/\/pingtungtimes.com.tw\/?p=38009","name":"\u81fa\u7f8e\u8ad6\u6230\u3000\u7b46\u6230\u6642\u75ab - 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As chloroquine is not available in Korea, doctors could consider hydroxychloroquine 400mg orally per day, they said. There is no evidence that using lopinavir\/ritonavir with chloroquine is more effective than monotherapies, they added. In contrast, Chinese doctors recommend in their journal article to take chloroquine 500mg orally twice per day. \u25cf Dr. Robin\uff1a Based on clinicaltrials.gov info, Remdesivir studies are IV infusion of 40 mL in 3 hours, loading dose of 200mg and maintenance dose of 100mg for 4 or 9 days. Assuming efficacious, it is difficult to implement in pandemic situation. Wouldn't SC infusion be much easier to implement in a pandemic situation? I am hoping to look into this via BMGF for its PK, safety\/efficacy and tolerability. Will contact you privately. \u25cf Dr. Y-C,Hung\uff1a These are recommendations based on no evidence, something we call it expert opinion, the lowest level in evidence-based medicine. \u5982\u679c\u662f clinical trials \u7684\u4e00\u90e8\u5206\uff0c\u90a3\u662f\u53ef\u4ee5\u63a5\u53d7\u7684\uff0c\u4f46\u662f\u7528\u5728\u6240\u6709\u4eba\u662f\u9055\u53cd\u91ab\u5b78\u4e0a\u7684\u7b2c\u4e00\u539f\u5247\uff0cDo no harm. \u25cf Dr. Spencer\uff1a https:\/\/www.bbc.com\/news\/amp\/technology-51851292 Coronavirus: How can AI help fight the pandemic?  BBC \u25cf Dr. Spencer\uff1a https:\/\/cms.wj411.com\/portal\/index\/newshare_weibo.jsp?id=2217380&source=13 \u25cf \u5f90\u91ab\u5e2b\uff1a \u7fa9\u5927\u5229\u6b7b\u4ea1\u7387\u9ad8\u5f97\u96e2\u5947\uff01\u6bba\u4eba\u5147\u624b\u662f\u9023\u7e8c10\u5e74\u7684\u7dca\u7e2e\u653f\u7b56\uff01 \u622a\u81f33\u670813\u65e5\uff0c\u7fa9\u5927\u5229\u7684\u6b7b\u4ea1\u7387\u78346.7\uff05\uff0c\u5168\u7403\u4e4b\u6700\uff01 \u5168\u7403\u570b\u5bb6\u8001\u5316\u7a0b\u5ea6\u6392\u540d\uff1a \u51a0\u8ecd\uff1a\u65e5\u672c27% \u4e9e\u8ecd\uff1a\u7fa9\u5927\u522923% \u5b63\u8ecd\uff1a\u5fb7\u570b21% \u6b64\u6b21\u6b66\u6f22\u75c5\u6bd2\u6b7b\u4ea1\u7387\uff1a \u7fa9\u5927\u5229\uff1a6.7% \u65e5\u672c\uff1a2.8% \u5fb7\u570b\uff1a0.2% \u90fd\u7a81\u986f\u7fa9\u5927\u5229\u7684\u9ad8\u6b7b\u4ea1\u7387\u4e0d\u5408\u7406\u3002 \u7f8e\u570b\u5a92\u9ad4\u300a\u83ef\u723e\u8857\u65e5\u5831\u300b\uff08Wall Street Journal\uff09\u5f15\u7576\u5730\u570b\u5bb6\u885b\u751f\u5c40\u7d71\u8a08\u6578\u64da\uff1a \u81f3\u4eca\u6b66\u80ba\u6b7b\u8005\u4e2d\uff0c 58%\u5e74\u9f61\u8d85\u904e80\u6b72\u3001 31%\u843d\u572870\u591a\u6b72\u3002 \u5e15\u591a\u74e6\u5927\u5b78\uff08University of Padua\uff09\u75c5\u6bd2\u5b78\u5bb6\u5e15\u9b6f\uff08Giorgio Pal\u00f9\uff09\u8aaa\uff1a\u300c\u751f\u7269\u5b78\u7684\u89d2\u5ea6\u7121\u6cd5\u89e3\u91cb\uff0c\u552f\u4e00\u80af\u5b9a\u7684\u662f\uff0c\u7fa9\u5927\u5229\u582a\u7a31\u5168\u4e16\u754c\u4eba\u53e3\u6700\u5e74\u8001\u7684\u570b\u5bb6\u4e4b\u4e00\u3002\u300d \u25cf Dr. Chen\uff1a https:\/\/zh.wikipedia.org\/wiki\/%E5%AE%89%E4%B8%9C%E5%B0%BC%C2%B7%E5%BC%97%E5%A5%91 \u5b89\u4e86\uff01\uff08\u5ddd\u666e\u8001\u4eba\u958b\u807d\u6bd4\u4ed6\u9084\u8001\u7684\u5b89\u6771\u5c3c.\u5f17\u5951\u5c08\u5bb6\uff09 \u9019\u500b\u6642\u5019\uff0c\u642c\u6f14\u548c\u4e8b\u4f6c\u7684\u9673\u540c\u5b78\u53c8\u51fa\u4f86\u6253\u5713\u5834\u4e86\uff0c\u5176\u5be6\u9673\u540c\u5b78\u624d\u662f\u771f\u6b63\u7684\u91ab\u5b78\u5c08\u5bb6\uff0c\u56e0\u70ba\u4ed6\u670d\u52d9\u7684\u516c\u53f8\u662f\u5168\u5e02\u6700\u5927\u91ab\u7642\u96c6\u5718BD\u516c\u53f8\u3002 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