{"id":380018,"date":"2025-11-07T21:30:00","date_gmt":"2025-11-07T13:30:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=380018"},"modified":"2025-11-07T21:30:00","modified_gmt":"2025-11-07T13:30:00","slug":"%e9%a8%b0%e7%9b%9b%e5%8d%9a%e8%97%a5%e5%ae%a3%e4%bd%88%e5%9c%a8%e3%80%8a%e8%87%aa%e7%84%b6-%e9%86%ab%e5%ad%b8%e3%80%8b%e7%99%bc%e8%a1%a8ensure-ii%e6%9c%9f%e7%a0%94%e7%a9%b6%e7%b5%90%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=380018","title":{"rendered":"\u9a30\u76db\u535a\u85e5\u5ba3\u4f48\u5728\u300a\u81ea\u7136-\u91ab\u5b78\u300b\u767c\u8868ENSURE II\u671f\u7814\u7a76\u7d50\u679c"},"content":{"rendered":"<div>\n<table name=\"logo_release\" border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul type=\"disc\">\n<li><i>\u7814\u7a76\u7d50\u679c\u70ba\u5c0f\u5e72\u64fe\u6838\u7cd6\u6838\u9178\uff08<\/i><i>siRNA<\/i><i>\uff09\u53ca\u6cbb\u7642\u6027\u75ab\u82d7\u5728\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u7652\u7b56\u7565\u4e2d\u7684\u8ca2\u737b\u63d0\u4f9b\u4e86\u79d1\u5b78\u6d1e\u898b<\/i><\/li>\n<\/ul>\n<p><span class=\"legendSpanClass\">\u4e2d\u570b\u5317\u4eac\u548c\u7f8e\u570b\u5317\u5361\u7f85\u840a\u7d0d\u5dde\u9054\u52d2\u59c6\u5e02<\/span><span class=\"legendSpanClass\">2025\u5e7411\u67087\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; <a href=\"https:\/\/www.briibio.com\/cn\/\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">\u9a30\u76db\u535a\u85e5\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8<\/a>\uff08\u300c\u9a30\u76db\u535a\u85e5\u300d\u6216\u300c\u516c\u53f8\u300d\uff0c\u80a1\u7968\u4ee3\u78bc\uff1a2137.HK\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u65bc\u91dd\u5c0d\u60a3\u8005\u9700\u6c42\u672a\u88ab\u6eff\u8db3\u7684\u75be\u75c5\u958b\u767c\u6cbb\u7642\u65b9\u6848\uff0c\u4ee5\u6539\u5584\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u548c\u6cbb\u7642\u9078\u64c7\u7684\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\u5176ENSURE II\u671f\u7814\u7a76\u7d50\u679c\u5df2\u767c\u8868\u65bc\u540c\u884c\u8a55\u5be9\u671f\u520a\u300a\u81ea\u7136-\u91ab\u5b78\u300b\u3002\u7814\u7a76\u8a55\u4f30\u4e86siRNA\u85e5\u7269elebsiran\u806f\u5408\u805a\u4e59\u4e8c\u9187\u5e72\u64fe\u7d20\u03b1\uff08PEG-IFN\u03b1\uff09\u6cbb\u7642\u65b9\u6848\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u4e26\u5c07PEG-IFN\u03b1\u55ae\u85e5\u6cbb\u7642\u65b9\u6848\u4f5c\u70ba\u5c0d\u7167\u7d44\u3002\u6b64\u5916\uff0c\u8a72\u7814\u7a76\u9084\u63a2\u8a0e\u4e86\u4e59\u809d\u6cbb\u7642\u6027\u75ab\u82d7BRII-179\u5728\u8b58\u5225\u514d\u75ab\u61c9\u7b54\u60a3\u8005\u53ca\u63d0\u9ad8\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6e05\u9664\u7387\u4e2d\u7684\u6f5b\u5728\u4f5c\u7528\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p>\u6a19\u984c\u70ba\u300aElebsiran\u548cPEG-IFN\u03b1\u6cbb\u7642\u6162\u6027\u4e59\u578b\u809d\u708e\u611f\u67d3\uff1a\u4e00\u9805\u90e8\u5206\u96a8\u6a5f\u3001\u958b\u653e\u6a19\u7c64\u7684II\u671f\u81e8\u5e8a\u8a66\u9a57\u300b\u7684\u6587\u7ae0\u73fe\u5df2\u4e0a\u7dda\u3010<a href=\"https:\/\/www.nature.com\/articles\/s41591-025-04049-z\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">\u93c8\u63a5<\/a>\u3011\u3002<\/p>\n<p>ENSURE\u7814\u7a76\u5728\u75c5\u6bd2\u6291\u5236\u7684\u6162\u6027HBV\u60a3\u8005\u4e2d\u5206\u5169\u90e8\u5206\u9032\u884c\u3002\u5728\u7b2c\u4e00\u90e8\u5206\uff08\u968a\u52171-3\uff09\u4e2d\uff0c\u672a\u63a5\u53d7\u904eBRII-179\u7d66\u85e5\u7684\u53c3\u8207\u8005\u96a8\u6a5f\u63a5\u53d748\u5468\u7684PEG-IFN\u03b1\u55ae\u85e5\u6cbb\u7642\uff0c\u6216\u806f\u5408elebsiran\u6cbb\u7642\uff08\u6bcf4\u5468\u7d66\u85e5\u4e00\u6b21\uff08Q4W\uff09\uff0c\u5291\u91cf\u70ba200mg\u6216100mg\uff09\u3002\u5728\u7b2c\u4e8c\u90e8\u5206\uff08\u968a\u52174\uff09\u4e2d\uff0c\u5728\u5148\u524d\u5df2\u5b8c\u6210\u7684II\u671f\u7814\u7a76\uff08BRII-179-835-001\uff09\u4e2d\u63a5\u53d7\u904e9\u5291elebsiran\u806f\u5408BRII-179\u7d66\u85e5\u7684\u53c3\u8207\u8005\uff0c\u6839\u64da\u4e59\u809d\u8868\u9762\u6297\u9ad4\uff08anti-HBs\uff09\u6ef4\u5ea6\u5cf0\u503c\u6c34\u5e73\uff08\u5206\u5225\u70ba\u226510 IU\/L\u6216&lt;10 IU\/L\uff09\u88ab\u5206\u985e\u70baBRII-179\u6297-HBs\u61c9\u7b54\u8005\u6216\u7121\u61c9\u7b54\u8005\uff0c\u96a8\u5f8c\u5728ENSURE\u7814\u7a76\u4e2d\u63a5\u53d748\u5468\u7684elebsiran\uff08100 mg Q4W\uff09\u806f\u5408\u6bcf\u9031PEG-IFN\u03b1\u6cbb\u7642\u3002<\/p>\n<p>\u8a72\u8ad6\u6587\u7684\u95dc\u9375\u7d50\u679c\u5305\u62ec\uff1a<\/p>\n<ul type=\"disc\">\n<li><b>\u968a\u52171-3\uff1a<\/b>\u5728\u6cbb\u7642\u7d50\u675f\u5f8c24\u5468\uff0c\u5728\u968a\u52172\uff08elebsiran 200mg + PEG-IFN\u03b1\uff09\u768419\u540d\u53c3\u8207\u8005\u4e2d4\u4f8b\uff0821.1%\uff09\u5be6\u73fe\u4e86HBsAg\u6e05\u9664\uff1b\u5728\u968a\u52173\uff08elebsiran 100 mg + PEG-IFN\u03b1\uff09\u768418 \u540d\u53c3\u8207\u8005\u4e2d6\u4f8b\uff0833.3%\uff09\u5be6\u73fe\u4e86HBsAg\u6e05\u9664\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u968a\u52171\uff08PEG-IFN\u03b1\u55ae\u85e5\uff0918\u540d\u53c3\u8207\u8005\u4e2d\u50c5\u67091\u4f8b\uff085.6%\uff09\u5be6\u73fe\u4e86HBsAg\u6e05\u9664\u3002<\/li>\n<li><b>\u968a\u52174\uff1a<\/b>\u5728\u6cbb\u7642\u7d50\u675f\u5f8c24\u5468\uff0c\u53c3\u8207\u8005\u4e2dBRII-179\u6297-HBs\u61c9\u7b54\u8005\u7684\u61c9\u7b54\u7387\u70ba41.1%\uff0819\u540d\u53c3\u8207\u8005\u4e2d8\u540d\uff09\uff0c\u986f\u8457\u9ad8\u65bc\u7121\u61c9\u7b54\u8005\uff0812\u540d\u53c3\u8207\u8005\u4e2d1\u540d\uff0c8.3%\uff09\u3002\u6240\u6709 31\u540d\u53c3\u8207\u8005\u4e2d\u67099\u540d\uff0829.0%\uff09\u5be6\u73fe\u4e86HBsAg\u6e05\u9664\u3002\u6b64\u5916\uff0cBRII-179\u6297-HBs\u61c9\u7b54\u8005\u6bd4\u7121\u61c9\u7b54\u8005\u66f4\u5feb\u901f\u5730\u5be6\u73fe\u4e86HBsAg\u964d\u4f4e\u548c\u6e05\u9664\u3002<\/li>\n<li>\u5728\u6240\u6709\u7814\u7a76\u968a\u5217\u4e2d\uff0cElebsiran\u8207PEG-IFN\u03b1\u806f\u5408\u7642\u6cd5\u7e3d\u9ad4\u5b89\u5168\u4e14\u8010\u53d7\u6027\u826f\u597d\u3002<\/li>\n<\/ul>\n<p>\u7b2c1-3\u968a\u5217\u63a1\u7528\u7684\u96a8\u6a5f\u3001\u967d\u6027\u5c0d\u7167\u8a2d\u8a08\uff0c\u662f\u9a57\u8b49elebsiran\u806f\u7528\u76f8\u8f03\u65bcPEG-IFN\u03b1\u55ae\u85e5\u6cbb\u7642\u81e8\u5e8a\u7372\u76ca\u7684\u91d1\u6a19\u6e96\uff0c\u70ba\u672a\u4f86siRNA\u85e5\u7269\u5728\u4e59\u578b\u809d\u708e\u529f\u80fd\u6027\u6cbb\u7652\u4e0a\u7684\u7814\u767c\u63d0\u4f9b\u4e86\u91cd\u8981\u57fa\u6e96\u3002<\/p>\n<p>\u968a\u52174\u7684\u5275\u65b0\u8a2d\u8a08\u63a2\u7d22\u4e86\u4e00\u7a2e\u57fa\u65bc\u60a3\u8005\u53cd\u61c9\u7684\u6cbb\u7642\u65b9\u6848\uff0c\u65e8\u5728\u5be6\u73fe\u66f4\u500b\u6027\u5316\u7684\u6cbb\u7642\u6c7a\u7b56\uff0c\u65e2\u80fd\u6700\u5927\u5316\u9ad8\u7372\u76ca\u4eba\u7fa4\u7684\u61c9\u7b54\u7387\uff0c\u53c8\u80fd\u907f\u514d\u5176\u4ed6\u60a3\u8005\u63a5\u53d7\u4e0d\u5fc5\u8981\u4e14\u5197\u9577\u7684\u6cbb\u7642\u3002<\/p>\n<p>\u5176\u4ed6\u91cd\u8981\u89c0\u5bdf\u7d50\u679c\u5305\u62ec\uff1a1) BRII-179\u806f\u5408elebsiran\u6cbb\u7642\u7684\u7d93\u6cbb\u53c3\u8207\u8005\u51fa\u73feHBsAg\u964d\u4f4e\u548c\u6e05\u9664\u7684\u901f\u5ea6\u66f4\u5feb\uff0c\u8868\u660eBRII-179\u53ef\u80fd\u901a\u904e\u6fc0\u6d3b\u514d\u75ab\u7cfb\u7d71\uff0c\u589e\u5f37\u5176\u5c0d\u5f8c\u7e8c\u6cbb\u7652\u6027\u7642\u6cd5\u7684\u97ff\u61c9\u80fd\u529b\uff1b2) 50%\uff084\/8\uff09\u5be6\u73feHBsAg\u6301\u7e8c\u6e05\u9664\u7684\u6297-HBs\u61c9\u7b54\u8005\u5728\u5148\u524dBRII-179-835-001\u7814\u7a76\u4e2d\u5165\u7d44\u6642\u57fa\u7ddaHBsAg\u6c34\u5e73\u8d85\u904e1,500 IU\/mL\uff0c\u8868\u660eBRII-179\u53ef\u80fd\u5728HBsAg\u57fa\u7dda\u6c34\u5e73\u8f03\u9ad8\u7684\u60a3\u8005\u4e2d\u8a98\u5c0e\u6297-HBs\u61c9\u7b54\u3002\u6191\u501f\u5176\u826f\u597d\u7684\u5b89\u5168\u6027\u7279\u5fb5\uff0cBRII-179\u6709\u671b\u5728\u4e0d\u540cHBsAg\u57fa\u7dda\u6c34\u5e73\u7684\u60a3\u8005\u4e2d\u767c\u63ee\u7368\u7279\u7684\u60a3\u8005\u514d\u75ab\u548c\u5bcc\u96c6\u4f5c\u7528\uff0c\u5f9e\u800c\u64f4\u5927\u672a\u4f86\u6cbb\u7652\u6027\u6cbb\u7642\u65b9\u6848\u7684\u9069\u7528\u4eba\u7fa4\u7bc4\u570d\u3002<\/p>\n<p>ENSURE\u7814\u7a76\u7684\u9996\u5e2d\u7814\u7a76\u8005\u8cc8\u7e7c\u6771\u6559\u6388\u8868\u793a\uff1a\u300cENSURE\u7814\u7a76\u65e8\u5728\u70ba\u6162\u6027\u4e59\u578b\u809d\u708e\u7684\u6cbb\u7652\u6027\u7642\u6cd5\u63d0\u4f9b\u4e9f\u9700\u7684\u79d1\u5b78\u4f9d\u64da\u4e26\u56de\u7b54\u5176\u4e2d\u4e00\u4e9b\u95dc\u9375\u7684\u79d1\u5b78\u554f\u984c\u3002\u4ee4\u4eba\u9f13\u821e\u7684\u662f\uff0c24\u5468\u96a8\u8a2a\u6578\u64da\u8207\u6cbb\u7642\u7d50\u675f\u6642\u7684\u7d50\u679c\u8da8\u52e2\u4e00\u81f4\uff0c\u8a72\u7d50\u679c\u70baelebsiran\u7684\u984d\u5916\u81e8\u5e8a\u7372\u76ca\u63d0\u4f9b\u4e86\u9032\u4e00\u6b65\u7684\u652f\u6301\uff0c\u540c\u6642\u63d0\u793a\u4e86BRII-179\u5728\u6fc0\u6d3b\u6162\u6027\u4e59\u809d\u60a3\u8005\u514d\u75ab\u4e26\u5bcc\u96c6\u8a72\u4eba\u7fa4\u4ee5\u5be6\u73fe\u66f4\u9ad8\u529f\u80fd\u6027\u6cbb\u7652\u7387\u65b9\u9762\u7684\u6f5b\u5728\u65b0\u4f5c\u7528\u3002\u6211\u5011\u671f\u5f85\u5728\u5f8c\u7e8c\u7684\u9a57\u8b49\u6027\u7814\u7a76\u4e2d\u9032\u4e00\u6b65\u78ba\u8a8d\u9019\u4e9b\u767c\u73fe\u3002\u300d<\/p>\n<p><b>\u95dc\u65bc\u4e59\u578b\u809d\u708e<\/b><\/p>\n<p>\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u662f\u4e16\u754c\u4e0a\u6700\u91cd\u5927\u7684\u611f\u67d3\u6027\u75be\u75c5\u5a01\u8105\u4e4b\u4e00\uff0c\u5168\u7403\u611f\u67d3\u4eba\u6578\u8d85\u904e2.54\u5104\u3002<sup>[1]<\/sup>\u6162\u6027HBV\u611f\u67d3\u662f\u809d\u81df\u75be\u75c5\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u6bcf\u5e74\u7d04\u670982\u842c\u4eba\u6b7b\u65bc\u6162\u6027HBV\u611f\u67d3\u7684\u4f75\u767c\u75c7\u3002<sup>[1]<\/sup>\u4e2d\u570b\u6162\u6027HBV\u611f\u67d3\u4eba\u6578\u90548,700\u842c\uff0c\u975e\u5e38\u503c\u5f97\u95dc\u6ce8\u3002<sup>[2]<\/sup><\/p>\n<p><b>\u95dc\u65bcBRII-179<\/b><\/p>\n<p>BRII-179\u662f\u4e00\u7a2e\u57fa\u65bc\u91cd\u7d44\u86cb\u767d\u8cea\u7684\u65b0\u578bHBV \u514d\u75ab\u6cbb\u7642\u5019\u9078\u85e5\u7269\uff0c\u53ef\u8868\u9054HBV\u7684Pre-S1\u3001Pre-S2\u548cS\u8868\u9762\u6297\u539f\uff0c\u65e8\u5728\u8a98\u5c0e\u589e\u5f37\u548c\u5ee3\u6cdb\u7684B\u7d30\u80de\u548cT\u7d30\u80de\u514d\u75ab\u61c9\u7b54\u30022023\u5e7411\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88BRII-179\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\u8a8d\u5b9a\u3002<\/p>\n<p><b>\u95dc\u65bcElebsiran<\/b><\/p>\n<p>Elebsiran\u662f\u4e00\u7a2e\u7d93\u76ae\u4e0b\u6ce8\u5c04\u7d66\u85e5\u7684\u9776\u5411\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u7684\u5c0f\u5e72\u64fe\u6838\u7cd6\u6838\u9178\uff08siRNA\uff09\u7814\u7a76\u6027\u85e5\u7269\uff0c\u65e8\u5728\u964d\u89e3HBV RNA\u8f49\u9304\u672c\u53ca\u9650\u5236\u4e59\u578b\u809d\u708e\u8868\u9762\u6297\u539f\u7684\u7522\u751f\uff0c\u5176\u5177\u6709\u91dd\u5c0dHBV\u53ca\u4e01\u578b\u809d\u708e\u75c5\u6bd2\uff08HDV\uff09\u7684\u76f4\u63a5\u6297\u75c5\u6bd2\u6d3b\u6027\u3002\u5176\u662f\u9996\u500b\u9032\u5165\u81e8\u5e8a\u7684\u63a1\u7528\u589e\u5f37\u7a69\u5b9a\u5316\u5b78\u589e\u5f37\u6280\u8853\u7684siRNA\uff0c\u4ee5\u589e\u5f37\u7a69\u5b9a\u6027\u4e26\u6700\u5927\u7a0b\u5ea6\u5730\u6e1b\u5c11\u812b\u9776\u6d3b\u6027\uff0c\u5f9e\u800c\u6709\u53ef\u80fd\u63d0\u9ad8\u6cbb\u7642\u6307\u6578\u3002\u9a30\u76db\u535a\u85e5\u65bc2020\u5e74\u5f9eVir Biotechnology, Inc. \u7372\u5f97\u4e86\u5728\u5927\u4e2d\u83ef\u5730\u5340\u958b\u767c\u548c\u5546\u696d\u5316elebsiran\u7684\u7368\u5bb6\u6b0a\u76ca\u30022024\u5e745\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88elebsiran\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\u8a8d\u5b9a\u3002<\/p>\n<p><b>\u95dc\u65bc\u9a30\u76db\u535a\u85e5<\/b><\/p>\n<p>\u9a30\u76db\u535a\u85e5\uff08\u80a1\u7968\u4ee3\u78bc\uff1a2137.HK\uff09\u662f\u4e00\u5bb6\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u91dd\u5c0d\u5b58\u5728\u5de8\u5927\u672a\u88ab\u6eff\u8db3\u7684\u60a3\u8005\u9700\u6c42\u3001\u6cbb\u7642\u624b\u6bb5\u6709\u9650\uff0c\u4ee5\u53ca\u7d66\u60a3\u8005\u5e36\u4f86\u56b4\u91cd\u793e\u6703\u6b67\u8996\u7684\u91cd\u5927\u516c\u5171\u885b\u751f\u6311\u6230\u958b\u767c\u5275\u65b0\u7642\u6cd5\u3002\u516c\u53f8\u5c08\u6ce8\u65bc\u611f\u67d3\u6027\u75be\u75c5\uff0c\u6b63\u5728\u63a8\u9032\u4e00\u689d\u6db5\u84cb\u591a\u7a2e\u7368\u7279\u5019\u9078\u85e5\u7269\u7684\u7522\u54c1\u7ba1\u7dda\uff0c\u91cd\u9ede\u5305\u62ec\u91dd\u5c0d\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u7684\u9818\u5148\u9805\u76ee\u3002\u5728\u5bcc\u6709\u9060\u898b\u5353\u8b58\u548c\u7d93\u9a57\u8c50\u5bcc\u7684\u9818\u5c0e\u5718\u968a\u5e36\u9818\u4e0b\uff0c\u516c\u53f8\u5728\u4f4d\u65bc\u7f85\u5229-\u9054\u52d2\u59c6\u3001\u820a\u91d1\u5c71\u7063\u5340\u3001\u5317\u4eac\u548c\u4e0a\u6d77\u7684\u4e3b\u8981\u751f\u7269\u6280\u8853\u4e2d\u5fc3\u958b\u5c55\u696d\u52d9\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u00a0<a href=\"https:\/\/www.briibio.com\/cn\/\" target=\"_blank\" rel=\"nofollow\" style=\"color: #0000FF\">www.briibio.com<\/a>\u3002<\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">[1] World\u00a0Health Organization. (April 2024). Global hepatitis report 2024: action for access in low- and middle-income countries. World Health Organization. Retrieved from\u00a0<a href=\"https:\/\/www.who.int\/publications\/i\/item\/9789240091672\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow\" style=\"color: #0000FF\">https:\/\/www.who.int\/publications\/i\/item\/9789240091672<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">[2] World Health Organization. Hepatitis. World Health Organization. Retrieved from\u00a0<a href=\"https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C.\" target=\"_blank\" class=\"prnews_a\" rel=\"nofollow\" style=\"color: #0000FF\">https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C.<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>\u00a0<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u7d50\u679c\u70ba\u5c0f\u5e72\u64fe\u6838\u7cd6\u6838\u9178\uff08si&#8230;<\/p>\n","protected":false},"author":16,"featured_media":380019,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-380018","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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BRII-179\u806f\u5408elebsiran\u6cbb\u7642\u7684\u7d93\u6cbb\u53c3\u8207\u8005\u51fa\u73feHBsAg\u964d\u4f4e\u548c\u6e05\u9664\u7684\u901f\u5ea6\u66f4\u5feb\uff0c\u8868\u660eBRII-179\u53ef\u80fd\u901a\u904e\u6fc0\u6d3b\u514d\u75ab\u7cfb\u7d71\uff0c\u589e\u5f37\u5176\u5c0d\u5f8c\u7e8c\u6cbb\u7652\u6027\u7642\u6cd5\u7684\u97ff\u61c9\u80fd\u529b\uff1b2) 50%\uff084\/8\uff09\u5be6\u73feHBsAg\u6301\u7e8c\u6e05\u9664\u7684\u6297-HBs\u61c9\u7b54\u8005\u5728\u5148\u524dBRII-179-835-001\u7814\u7a76\u4e2d\u5165\u7d44\u6642\u57fa\u7ddaHBsAg\u6c34\u5e73\u8d85\u904e1,500 IU\/mL\uff0c\u8868\u660eBRII-179\u53ef\u80fd\u5728HBsAg\u57fa\u7dda\u6c34\u5e73\u8f03\u9ad8\u7684\u60a3\u8005\u4e2d\u8a98\u5c0e\u6297-HBs\u61c9\u7b54\u3002\u6191\u501f\u5176\u826f\u597d\u7684\u5b89\u5168\u6027\u7279\u5fb5\uff0cBRII-179\u6709\u671b\u5728\u4e0d\u540cHBsAg\u57fa\u7dda\u6c34\u5e73\u7684\u60a3\u8005\u4e2d\u767c\u63ee\u7368\u7279\u7684\u60a3\u8005\u514d\u75ab\u548c\u5bcc\u96c6\u4f5c\u7528\uff0c\u5f9e\u800c\u64f4\u5927\u672a\u4f86\u6cbb\u7652\u6027\u6cbb\u7642\u65b9\u6848\u7684\u9069\u7528\u4eba\u7fa4\u7bc4\u570d\u3002 ENSURE\u7814\u7a76\u7684\u9996\u5e2d\u7814\u7a76\u8005\u8cc8\u7e7c\u6771\u6559\u6388\u8868\u793a\uff1a\u300cENSURE\u7814\u7a76\u65e8\u5728\u70ba\u6162\u6027\u4e59\u578b\u809d\u708e\u7684\u6cbb\u7652\u6027\u7642\u6cd5\u63d0\u4f9b\u4e9f\u9700\u7684\u79d1\u5b78\u4f9d\u64da\u4e26\u56de\u7b54\u5176\u4e2d\u4e00\u4e9b\u95dc\u9375\u7684\u79d1\u5b78\u554f\u984c\u3002\u4ee4\u4eba\u9f13\u821e\u7684\u662f\uff0c24\u5468\u96a8\u8a2a\u6578\u64da\u8207\u6cbb\u7642\u7d50\u675f\u6642\u7684\u7d50\u679c\u8da8\u52e2\u4e00\u81f4\uff0c\u8a72\u7d50\u679c\u70baelebsiran\u7684\u984d\u5916\u81e8\u5e8a\u7372\u76ca\u63d0\u4f9b\u4e86\u9032\u4e00\u6b65\u7684\u652f\u6301\uff0c\u540c\u6642\u63d0\u793a\u4e86BRII-179\u5728\u6fc0\u6d3b\u6162\u6027\u4e59\u809d\u60a3\u8005\u514d\u75ab\u4e26\u5bcc\u96c6\u8a72\u4eba\u7fa4\u4ee5\u5be6\u73fe\u66f4\u9ad8\u529f\u80fd\u6027\u6cbb\u7652\u7387\u65b9\u9762\u7684\u6f5b\u5728\u65b0\u4f5c\u7528\u3002\u6211\u5011\u671f\u5f85\u5728\u5f8c\u7e8c\u7684\u9a57\u8b49\u6027\u7814\u7a76\u4e2d\u9032\u4e00\u6b65\u78ba\u8a8d\u9019\u4e9b\u767c\u73fe\u3002\u300d \u95dc\u65bc\u4e59\u578b\u809d\u708e \u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u662f\u4e16\u754c\u4e0a\u6700\u91cd\u5927\u7684\u611f\u67d3\u6027\u75be\u75c5\u5a01\u8105\u4e4b\u4e00\uff0c\u5168\u7403\u611f\u67d3\u4eba\u6578\u8d85\u904e2.54\u5104\u3002\u6162\u6027HBV\u611f\u67d3\u662f\u809d\u81df\u75be\u75c5\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u6bcf\u5e74\u7d04\u670982\u842c\u4eba\u6b7b\u65bc\u6162\u6027HBV\u611f\u67d3\u7684\u4f75\u767c\u75c7\u3002\u4e2d\u570b\u6162\u6027HBV\u611f\u67d3\u4eba\u6578\u90548,700\u842c\uff0c\u975e\u5e38\u503c\u5f97\u95dc\u6ce8\u3002 \u95dc\u65bcBRII-179 BRII-179\u662f\u4e00\u7a2e\u57fa\u65bc\u91cd\u7d44\u86cb\u767d\u8cea\u7684\u65b0\u578bHBV \u514d\u75ab\u6cbb\u7642\u5019\u9078\u85e5\u7269\uff0c\u53ef\u8868\u9054HBV\u7684Pre-S1\u3001Pre-S2\u548cS\u8868\u9762\u6297\u539f\uff0c\u65e8\u5728\u8a98\u5c0e\u589e\u5f37\u548c\u5ee3\u6cdb\u7684B\u7d30\u80de\u548cT\u7d30\u80de\u514d\u75ab\u61c9\u7b54\u30022023\u5e7411\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88BRII-179\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\u8a8d\u5b9a\u3002 \u95dc\u65bcElebsiran Elebsiran\u662f\u4e00\u7a2e\u7d93\u76ae\u4e0b\u6ce8\u5c04\u7d66\u85e5\u7684\u9776\u5411\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u7684\u5c0f\u5e72\u64fe\u6838\u7cd6\u6838\u9178\uff08siRNA\uff09\u7814\u7a76\u6027\u85e5\u7269\uff0c\u65e8\u5728\u964d\u89e3HBV RNA\u8f49\u9304\u672c\u53ca\u9650\u5236\u4e59\u578b\u809d\u708e\u8868\u9762\u6297\u539f\u7684\u7522\u751f\uff0c\u5176\u5177\u6709\u91dd\u5c0dHBV\u53ca\u4e01\u578b\u809d\u708e\u75c5\u6bd2\uff08HDV\uff09\u7684\u76f4\u63a5\u6297\u75c5\u6bd2\u6d3b\u6027\u3002\u5176\u662f\u9996\u500b\u9032\u5165\u81e8\u5e8a\u7684\u63a1\u7528\u589e\u5f37\u7a69\u5b9a\u5316\u5b78\u589e\u5f37\u6280\u8853\u7684siRNA\uff0c\u4ee5\u589e\u5f37\u7a69\u5b9a\u6027\u4e26\u6700\u5927\u7a0b\u5ea6\u5730\u6e1b\u5c11\u812b\u9776\u6d3b\u6027\uff0c\u5f9e\u800c\u6709\u53ef\u80fd\u63d0\u9ad8\u6cbb\u7642\u6307\u6578\u3002\u9a30\u76db\u535a\u85e5\u65bc2020\u5e74\u5f9eVir Biotechnology, Inc. \u7372\u5f97\u4e86\u5728\u5927\u4e2d\u83ef\u5730\u5340\u958b\u767c\u548c\u5546\u696d\u5316elebsiran\u7684\u7368\u5bb6\u6b0a\u76ca\u30022024\u5e745\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88elebsiran\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\u8a8d\u5b9a\u3002 \u95dc\u65bc\u9a30\u76db\u535a\u85e5 \u9a30\u76db\u535a\u85e5\uff08\u80a1\u7968\u4ee3\u78bc\uff1a2137.HK\uff09\u662f\u4e00\u5bb6\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u91dd\u5c0d\u5b58\u5728\u5de8\u5927\u672a\u88ab\u6eff\u8db3\u7684\u60a3\u8005\u9700\u6c42\u3001\u6cbb\u7642\u624b\u6bb5\u6709\u9650\uff0c\u4ee5\u53ca\u7d66\u60a3\u8005\u5e36\u4f86\u56b4\u91cd\u793e\u6703\u6b67\u8996\u7684\u91cd\u5927\u516c\u5171\u885b\u751f\u6311\u6230\u958b\u767c\u5275\u65b0\u7642\u6cd5\u3002\u516c\u53f8\u5c08\u6ce8\u65bc\u611f\u67d3\u6027\u75be\u75c5\uff0c\u6b63\u5728\u63a8\u9032\u4e00\u689d\u6db5\u84cb\u591a\u7a2e\u7368\u7279\u5019\u9078\u85e5\u7269\u7684\u7522\u54c1\u7ba1\u7dda\uff0c\u91cd\u9ede\u5305\u62ec\u91dd\u5c0d\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u7684\u9818\u5148\u9805\u76ee\u3002\u5728\u5bcc\u6709\u9060\u898b\u5353\u8b58\u548c\u7d93\u9a57\u8c50\u5bcc\u7684\u9818\u5c0e\u5718\u968a\u5e36\u9818\u4e0b\uff0c\u516c\u53f8\u5728\u4f4d\u65bc\u7f85\u5229-\u9054\u52d2\u59c6\u3001\u820a\u91d1\u5c71\u7063\u5340\u3001\u5317\u4eac\u548c\u4e0a\u6d77\u7684\u4e3b\u8981\u751f\u7269\u6280\u8853\u4e2d\u5fc3\u958b\u5c55\u696d\u52d9\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u00a0www.briibio.com\u3002           World\u00a0Health Organization. (April 2024). Global hepatitis report 2024: action for access in low- and middle-income countries. World Health Organization. Retrieved from\u00a0https:\/\/www.who.int\/publications\/i\/item\/9789240091672         World Health Organization. Hepatitis. World Health Organization. Retrieved from\u00a0https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C.         \u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=380018\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u9a30\u76db\u535a\u85e5\u5ba3\u4f48\u5728\u300a\u81ea\u7136-\u91ab\u5b78\u300b\u767c\u8868ENSURE II\u671f\u7814\u7a76\u7d50\u679c - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u7814\u7a76\u7d50\u679c\u70ba\u5c0f\u5e72\u64fe\u6838\u7cd6\u6838\u9178\uff08siRNA\uff09\u53ca\u6cbb\u7642\u6027\u75ab\u82d7\u5728\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u7652\u7b56\u7565\u4e2d\u7684\u8ca2\u737b\u63d0\u4f9b\u4e86\u79d1\u5b78\u6d1e\u898b  \u4e2d\u570b\u5317\u4eac\u548c\u7f8e\u570b\u5317\u5361\u7f85\u840a\u7d0d\u5dde\u9054\u52d2\u59c6\u5e022025\u5e7411\u67087\u65e5 \/\u7f8e\u901a\u793e\/ -- \u9a30\u76db\u535a\u85e5\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u300c\u9a30\u76db\u535a\u85e5\u300d\u6216\u300c\u516c\u53f8\u300d\uff0c\u80a1\u7968\u4ee3\u78bc\uff1a2137.HK\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u65bc\u91dd\u5c0d\u60a3\u8005\u9700\u6c42\u672a\u88ab\u6eff\u8db3\u7684\u75be\u75c5\u958b\u767c\u6cbb\u7642\u65b9\u6848\uff0c\u4ee5\u6539\u5584\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u548c\u6cbb\u7642\u9078\u64c7\u7684\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\u5176ENSURE II\u671f\u7814\u7a76\u7d50\u679c\u5df2\u767c\u8868\u65bc\u540c\u884c\u8a55\u5be9\u671f\u520a\u300a\u81ea\u7136-\u91ab\u5b78\u300b\u3002\u7814\u7a76\u8a55\u4f30\u4e86siRNA\u85e5\u7269elebsiran\u806f\u5408\u805a\u4e59\u4e8c\u9187\u5e72\u64fe\u7d20\u03b1\uff08PEG-IFN\u03b1\uff09\u6cbb\u7642\u65b9\u6848\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u4e26\u5c07PEG-IFN\u03b1\u55ae\u85e5\u6cbb\u7642\u65b9\u6848\u4f5c\u70ba\u5c0d\u7167\u7d44\u3002\u6b64\u5916\uff0c\u8a72\u7814\u7a76\u9084\u63a2\u8a0e\u4e86\u4e59\u809d\u6cbb\u7642\u6027\u75ab\u82d7BRII-179\u5728\u8b58\u5225\u514d\u75ab\u61c9\u7b54\u60a3\u8005\u53ca\u63d0\u9ad8\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6e05\u9664\u7387\u4e2d\u7684\u6f5b\u5728\u4f5c\u7528\u3002     \u6a19\u984c\u70ba\u300aElebsiran\u548cPEG-IFN\u03b1\u6cbb\u7642\u6162\u6027\u4e59\u578b\u809d\u708e\u611f\u67d3\uff1a\u4e00\u9805\u90e8\u5206\u96a8\u6a5f\u3001\u958b\u653e\u6a19\u7c64\u7684II\u671f\u81e8\u5e8a\u8a66\u9a57\u300b\u7684\u6587\u7ae0\u73fe\u5df2\u4e0a\u7dda\u3010\u93c8\u63a5\u3011\u3002 ENSURE\u7814\u7a76\u5728\u75c5\u6bd2\u6291\u5236\u7684\u6162\u6027HBV\u60a3\u8005\u4e2d\u5206\u5169\u90e8\u5206\u9032\u884c\u3002\u5728\u7b2c\u4e00\u90e8\u5206\uff08\u968a\u52171-3\uff09\u4e2d\uff0c\u672a\u63a5\u53d7\u904eBRII-179\u7d66\u85e5\u7684\u53c3\u8207\u8005\u96a8\u6a5f\u63a5\u53d748\u5468\u7684PEG-IFN\u03b1\u55ae\u85e5\u6cbb\u7642\uff0c\u6216\u806f\u5408elebsiran\u6cbb\u7642\uff08\u6bcf4\u5468\u7d66\u85e5\u4e00\u6b21\uff08Q4W\uff09\uff0c\u5291\u91cf\u70ba200mg\u6216100mg\uff09\u3002\u5728\u7b2c\u4e8c\u90e8\u5206\uff08\u968a\u52174\uff09\u4e2d\uff0c\u5728\u5148\u524d\u5df2\u5b8c\u6210\u7684II\u671f\u7814\u7a76\uff08BRII-179-835-001\uff09\u4e2d\u63a5\u53d7\u904e9\u5291elebsiran\u806f\u5408BRII-179\u7d66\u85e5\u7684\u53c3\u8207\u8005\uff0c\u6839\u64da\u4e59\u809d\u8868\u9762\u6297\u9ad4\uff08anti-HBs\uff09\u6ef4\u5ea6\u5cf0\u503c\u6c34\u5e73\uff08\u5206\u5225\u70ba\u226510 IU\/L\u6216&lt;10 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\u7372\u5f97\u4e86\u5728\u5927\u4e2d\u83ef\u5730\u5340\u958b\u767c\u548c\u5546\u696d\u5316elebsiran\u7684\u7368\u5bb6\u6b0a\u76ca\u30022024\u5e745\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88elebsiran\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\u8a8d\u5b9a\u3002 \u95dc\u65bc\u9a30\u76db\u535a\u85e5 \u9a30\u76db\u535a\u85e5\uff08\u80a1\u7968\u4ee3\u78bc\uff1a2137.HK\uff09\u662f\u4e00\u5bb6\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u91dd\u5c0d\u5b58\u5728\u5de8\u5927\u672a\u88ab\u6eff\u8db3\u7684\u60a3\u8005\u9700\u6c42\u3001\u6cbb\u7642\u624b\u6bb5\u6709\u9650\uff0c\u4ee5\u53ca\u7d66\u60a3\u8005\u5e36\u4f86\u56b4\u91cd\u793e\u6703\u6b67\u8996\u7684\u91cd\u5927\u516c\u5171\u885b\u751f\u6311\u6230\u958b\u767c\u5275\u65b0\u7642\u6cd5\u3002\u516c\u53f8\u5c08\u6ce8\u65bc\u611f\u67d3\u6027\u75be\u75c5\uff0c\u6b63\u5728\u63a8\u9032\u4e00\u689d\u6db5\u84cb\u591a\u7a2e\u7368\u7279\u5019\u9078\u85e5\u7269\u7684\u7522\u54c1\u7ba1\u7dda\uff0c\u91cd\u9ede\u5305\u62ec\u91dd\u5c0d\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u7684\u9818\u5148\u9805\u76ee\u3002\u5728\u5bcc\u6709\u9060\u898b\u5353\u8b58\u548c\u7d93\u9a57\u8c50\u5bcc\u7684\u9818\u5c0e\u5718\u968a\u5e36\u9818\u4e0b\uff0c\u516c\u53f8\u5728\u4f4d\u65bc\u7f85\u5229-\u9054\u52d2\u59c6\u3001\u820a\u91d1\u5c71\u7063\u5340\u3001\u5317\u4eac\u548c\u4e0a\u6d77\u7684\u4e3b\u8981\u751f\u7269\u6280\u8853\u4e2d\u5fc3\u958b\u5c55\u696d\u52d9\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u00a0www.briibio.com\u3002           World\u00a0Health Organization. (April 2024). Global hepatitis report 2024: action for access in low- and middle-income countries. World Health Organization. Retrieved from\u00a0https:\/\/www.who.int\/publications\/i\/item\/9789240091672         World Health Organization. Hepatitis. World Health Organization. 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\u7372\u5f97\u4e86\u5728\u5927\u4e2d\u83ef\u5730\u5340\u958b\u767c\u548c\u5546\u696d\u5316elebsiran\u7684\u7368\u5bb6\u6b0a\u76ca\u30022024\u5e745\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88elebsiran\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\u8a8d\u5b9a\u3002 \u95dc\u65bc\u9a30\u76db\u535a\u85e5 \u9a30\u76db\u535a\u85e5\uff08\u80a1\u7968\u4ee3\u78bc\uff1a2137.HK\uff09\u662f\u4e00\u5bb6\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u91dd\u5c0d\u5b58\u5728\u5de8\u5927\u672a\u88ab\u6eff\u8db3\u7684\u60a3\u8005\u9700\u6c42\u3001\u6cbb\u7642\u624b\u6bb5\u6709\u9650\uff0c\u4ee5\u53ca\u7d66\u60a3\u8005\u5e36\u4f86\u56b4\u91cd\u793e\u6703\u6b67\u8996\u7684\u91cd\u5927\u516c\u5171\u885b\u751f\u6311\u6230\u958b\u767c\u5275\u65b0\u7642\u6cd5\u3002\u516c\u53f8\u5c08\u6ce8\u65bc\u611f\u67d3\u6027\u75be\u75c5\uff0c\u6b63\u5728\u63a8\u9032\u4e00\u689d\u6db5\u84cb\u591a\u7a2e\u7368\u7279\u5019\u9078\u85e5\u7269\u7684\u7522\u54c1\u7ba1\u7dda\uff0c\u91cd\u9ede\u5305\u62ec\u91dd\u5c0d\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u7684\u9818\u5148\u9805\u76ee\u3002\u5728\u5bcc\u6709\u9060\u898b\u5353\u8b58\u548c\u7d93\u9a57\u8c50\u5bcc\u7684\u9818\u5c0e\u5718\u968a\u5e36\u9818\u4e0b\uff0c\u516c\u53f8\u5728\u4f4d\u65bc\u7f85\u5229-\u9054\u52d2\u59c6\u3001\u820a\u91d1\u5c71\u7063\u5340\u3001\u5317\u4eac\u548c\u4e0a\u6d77\u7684\u4e3b\u8981\u751f\u7269\u6280\u8853\u4e2d\u5fc3\u958b\u5c55\u696d\u52d9\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u00a0www.briibio.com\u3002           World\u00a0Health Organization. (April 2024). Global hepatitis report 2024: action for access in low- and middle-income countries. World Health Organization. Retrieved from\u00a0https:\/\/www.who.int\/publications\/i\/item\/9789240091672         World Health Organization. Hepatitis. World Health Organization. Retrieved from\u00a0https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C.         \u00a0","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pingtungtimes.com.tw\/?p=380018","og_locale":"zh_TW","og_type":"article","og_title":"\u9a30\u76db\u535a\u85e5\u5ba3\u4f48\u5728\u300a\u81ea\u7136-\u91ab\u5b78\u300b\u767c\u8868ENSURE II\u671f\u7814\u7a76\u7d50\u679c - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","og_description":"\u7814\u7a76\u7d50\u679c\u70ba\u5c0f\u5e72\u64fe\u6838\u7cd6\u6838\u9178\uff08siRNA\uff09\u53ca\u6cbb\u7642\u6027\u75ab\u82d7\u5728\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u7652\u7b56\u7565\u4e2d\u7684\u8ca2\u737b\u63d0\u4f9b\u4e86\u79d1\u5b78\u6d1e\u898b  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\u7372\u5f97\u4e86\u5728\u5927\u4e2d\u83ef\u5730\u5340\u958b\u767c\u548c\u5546\u696d\u5316elebsiran\u7684\u7368\u5bb6\u6b0a\u76ca\u30022024\u5e745\u6708\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u6388\u4e88elebsiran\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\u8a8d\u5b9a\u3002 \u95dc\u65bc\u9a30\u76db\u535a\u85e5 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          World\u00a0Health Organization. (April 2024). Global hepatitis report 2024: action for access in low- and middle-income countries. World Health Organization. Retrieved from\u00a0https:\/\/www.who.int\/publications\/i\/item\/9789240091672         World Health Organization. Hepatitis. World Health Organization. Retrieved from\u00a0https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C.         \u00a0","og_url":"https:\/\/pingtungtimes.com.tw\/?p=380018","og_site_name":"\u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","article_publisher":"https:\/\/www.facebook.com\/pingtungnews","article_published_time":"2025-11-07T13:30:00+00:00","og_image":[{"width":1706,"height":960,"url":"https:\/\/pingtungtimes.com.tw\/wp-content\/uploads\/2023\/02\/logo-150.png","type":"image\/jpeg"}],"author":"\u7f8e\u901a\u793e","twitter_card":"summary_large_image","twitter_misc":{"\u4f5c\u8005:":"\u7f8e\u901a\u793e","\u9810\u4f30\u95b1\u8b80\u6642\u9593":"1 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