{"id":316986,"date":"2025-04-26T08:00:00","date_gmt":"2025-04-26T00:00:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=316986"},"modified":"2025-04-26T08:00:00","modified_gmt":"2025-04-26T00:00:00","slug":"%e4%bf%a1%e9%81%94%e7%94%9f%e7%89%a9%e5%ae%a3%e4%bd%88%e8%88%87%e5%a5%a7%e8%b3%bd%e5%ba%b7%e5%90%88%e4%bd%9c%e7%9a%84%e7%ac%ac%e4%b8%89%e4%bb%a3egfr-tki-%e8%82%ba%e7%99%8c%e9%9d%b6%e5%90%91%e8%97%a5","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=316986","title":{"rendered":"\u4fe1\u9054\u751f\u7269\u5ba3\u4f48\u8207\u5967\u8cfd\u5eb7\u5408\u4f5c\u7684\u7b2c\u4e09\u4ee3EGFR TKI \u80ba\u764c\u9776\u5411\u85e5\u7269\u5967\u58f9\u65b0\u00ae\uff08\u5229\u5384\u66ff\u5c3c\u7247\uff09\u4e00\u7dda\u9069\u61c9\u75c7\u7372\u6279\u4e0a\u5e02"},"content":{"rendered":"<div>\n<p id=\"temp_ReleaseStart\"> <span class=\"legendSpanClass\">\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde<\/span> <span class=\"legendSpanClass\">2025\u5e744\u670826\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u4fe1\u9054\u751f\u7269\u88fd\u85e5\u96c6\u5718\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u80a1\u7968\u4ee3\u78bc\uff1a01801\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u65bc\u7814\u767c\u3001\u751f\u7522\u548c\u92b7\u552e\u816b\u7624\u3001\u81ea\u8eab\u514d\u75ab\u3001\u4ee3\u8b1d\u3001\u773c\u79d1\u7b49\u91cd\u5927\u75be\u75c5\u9818\u57df\u5275\u65b0\u85e5\u7269\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\u7b2c\u4e09\u4ee3\u8868\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u9ad4\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5291\uff08EGFR-TKI\uff09\u9776\u5411\u85e5\u7269\u5967\u58f9\u65b0<sup>\u00ae<\/sup>\uff08\u5229\u5384\u66ff\u5c3c\u7247\uff09\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\u7372\u5f97\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c\u7528\u65bc\u5177\u6709\u8868\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u9ad4\uff08EGFR\uff09\u5916\u986f\u5b5019\u7f3a\u5931\uff0819DEL\uff09\u6216\u5916\u986f\u5b5021\u7f6e\u63db\u7a81\u8b8a\uff08L858R\uff09\u7684\u5c40\u90e8\u665a\u671f\u6216\u5fa9\u767c\u8f49\u79fb\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u6210\u4eba\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002\u5967\u58f9\u65b0<sup>\u00ae<\/sup>\uff08\u5229\u5384\u66ff\u5c3c\u7247\uff09\u662f\u76ee\u524d\u552f\u4e00\u7372\u6279\u4e0a\u5e02\u7684\uff0c\u4ee5\u8418\u80fa\u7d50\u69cb\u70ba\u57fa\u790e\u7684\u7b2c\u4e09\u4ee3EGFR-TKI\u85e5\u7269\u3002\u6b64\u524d\uff0c\u4fe1\u9054\u751f\u7269\u8207\u5967\u8cfd\u5eb7\u85e5\u696d\u5c31\u5229\u5384\u66ff\u5c3c\u7247\u5728\u4e2d\u570b\u5df2\u9054\u6210\u7368\u5bb6\u5546\u696d\u5316\u5408\u4f5c\u3002<\/p>\n<p class=\"prntaj\">\u6b64\u6b21\u65b0\u9069\u61c9\u75c7\u7372\u6279\u662f\u57fa\u65bc\u4e00\u9805\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u967d\u6027\u5c0d\u7167III\u671f\u81e8\u5e8a\u7814\u7a76\u7684\u7a4d\u6975\u7d50\u679c\u3002\u8a72\u7814\u7a76\u5171\u7d0d\u5165337\u4f8b\u672a\u7d93\u7cfb\u7d71\u6027\u6cbb\u7642\u7684EGFR\u654f\u611f\u7a81\u8b8a\u967d\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027NSCLC\u60a3\u8005\uff0c\u63091:1\u6bd4\u4f8b\u96a8\u6a5f\u63a5\u53d7\u5229\u5384\u66ff\u5c3c\u6216\u5409\u975e\u66ff\u5c3c\u6cbb\u7642\u3002\u4e3b\u8981\u7814\u7a76\u7d42\u9ede\u662f\u7368\u7acb\u5be9\u8a55\u59d4\u54e1\u6703\uff08IRC\uff09\u8a55\u4f30\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u3002<\/p>\n<p class=\"prntaj\">\u7d50\u679c\u986f\u793a\uff0c\u8207\u5409\u975e\u66ff\u5c3c\u76f8\u6bd4\uff0c\u5229\u5384\u66ff\u5c3c\u986f\u8457\u5ef6\u9577\u4e86\u521d\u6cbbEGFR\u654f\u611f\u7a81\u8b8a\u967d\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684<b>\u4e2d\u4f4d<\/b><b>PFS<\/b><b>\uff08<\/b><b>20.7<\/b><b>\u500b\u6708<\/b><b>vs 9.7<\/b><b>\u500b\u6708\uff09\uff0c\u75be\u75c5\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u986f\u8457\u964d\u4f4e<\/b><b>56%<\/b>\uff08HR 0.44[95% CI: 0.34, 0.58]\uff0cp\uff1c0.0001\uff09\u3002\u5728\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\uff08CNS\uff09\u5b58\u5728\u53ef\u6e2c\u91cf\u75c5\u7076\u60a3\u8005\u4e2d\uff0c\u8207\u5409\u975e\u66ff\u5c3c\u76f8\u6bd4\uff0c\u5229\u5384\u66ff\u5c3c\u986f\u8457\u5ef6\u9577\u4e86<b>\u4e2d\u4f4d<\/b><b>CNS PFS<\/b><b>\uff08<\/b><b>20.7<\/b><b>\u500b\u6708<\/b><b>vs 7.1<\/b><b>\u500b\u6708\uff09\uff0c\u75be\u75c5\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u9ad8\u9054<\/b><b>72%<\/b>(HR 0.28[95% CI: 0.10, 0.82]\uff0cp=0.0136)\uff0c\u986f\u793a\u5c0d\u65bc\u8166\u8f49\u79fb\u60a3\u8005\u5177\u6709\u7a81\u51fa\u7684\u7642\u6548\u3002\u5229\u5384\u66ff\u5c3c\u4e3b\u8981\u4e0d\u826f\u53cd\u61c9\u70baEGFR\u9776\u9ede\u5e38\u898b\u4e0d\u826f\u53cd\u61c9\uff0c\u60a3\u8005\u8010\u53d7\u6027\u8f03\u597d\uff0c\u8a66\u9a57\u672a\u89c0\u5bdf\u5230\u65b0\u7684\u5b89\u5168\u6027\u4fe1\u865f\u3002\u8a72III\u671f\u81e8\u5e8a\u7814\u7a76\u7684\u76f8\u95dc\u6578\u64da\u53ca\u5206\u6790\u5c07\u5728\u6b0a\u5a01\u5b78\u8853\u671f\u520a\u4e0a\u767c\u8868\u3002<\/p>\n<p class=\"prntaj\"> <b>\u5229\u5384\u66ff\u5c3c\u4e00\u7dda\u6cbb\u7642\u665a\u671f\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u4e09\u671f\u81e8\u5e8a\u8a66\u9a57\u7684\u4e3b\u8981\u7814\u7a76\u8005\u3001\u4e2d\u570b\u91ab\u5b78\u79d1\u5b78\u9662\u816b\u7624\u91ab\u9662\u77f3\u9060\u51f1\u6559\u6388\u8868\u793a\uff1a<\/b>\u300c\u5229\u5384\u66ff\u5c3c\u5728EGFR\u57fa\u56e0\u654f\u611f\u7a81\u8b8a\u967d\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u4e2d\u8868\u73fe\u51fa\u4e86\u512a\u7570\u7684\u7642\u6548\u548c\u5b89\u5168\u6027\uff0c\u5c0d\u65bc\u8166\u8f49\u79fb\u60a3\u8005\u4ea6\u8868\u73fe\u51fa\u986f\u8457\u7684\u7642\u6548\uff0c\u4e00\u7dda\u9069\u61c9\u75c7\u7684\u7372\u6279\u70ba\u4e2d\u570bEGFR\u7a81\u8b8a\u967d\u6027NSCLC\u60a3\u8005\u5e36\u4f86\u4e86\u4e00\u7a2e\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u300d<\/p>\n<p class=\"prntaj\"> <b>\u4fe1\u9054\u751f\u7269\u88fd\u85e5\u96c6\u5718\u9ad8\u7d1a\u526f\u7e3d\u88c1\u5468\u8f1d\u535a\u58eb<\/b>\u8868\u793a\uff1a\u300c\u5f88\u9ad8\u8208\u5967\u58f9\u65b0<sup>\u00ae<\/sup>\uff08\u5229\u5384\u66ff\u5c3c\u7247\uff09\u7684\u4e00\u4e8c\u7dda\u9069\u61c9\u75c7\u63a5\u9023\u7372\u6279\uff0c\u4f5c\u70ba\u65b0\u4e00\u4ee3EGFR-TKI\u6709\u671b\u986f\u8457\u63d0\u5347\u7a81\u8b8a\u60a3\u8005\u751f\u5b58\u7372\u76ca\uff0c\u7d66\u5ee3\u6cdb\u7684EGFR\u7a81\u8b8a\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u4fe1\u9054\u751f\u7269\u5728\u80ba\u764c\u7cbe\u6e96\u7642\u6cd5\u9818\u57df\u64c1\u6709\u5305\u62ec\u5967\u58f9\u65b0<sup>\u00ae<\/sup>\u3001\u777f\u59a5<sup>\u00ae<\/sup>\u3001\u9054\u4f2f\u6a02<sup>\u00ae<\/sup>\u3001\u9054\u4f2f\u7279<sup>\u00ae<\/sup>\u7b49\u8c50\u539a\u7684\u9776\u5411\u85e5\u7269\u7d44\u5408\uff0c\u5354\u540c\u50f9\u503c\u6301\u7e8c\u63d0\u5347\u3002\u6211\u5011\u5c07\u8207\u5967\u8cfd\u5eb7\u85e5\u696d\u5354\u5fc3\u540c\u529b\uff0c\u4f7f\u5f97\u5967\u58f9\u65b0<sup>\u00ae<\/sup>\uff08\u5229\u5384\u66ff\u5c3c\u7247\uff09\u70baEGFR\u7a81\u8b8a\u7684NSCLC\u60a3\u8005\u9ede\u4eae\u7cbe\u6e96\u6cbb\u7642\u65b0\u66d9\u5149\u3002\u300d<\/p>\n<p class=\"prntaj\"> <b>\u5967\u8cfd\u5eb7\u85e5\u696d\u7e3d\u7d93\u7406\u99ac\u7af6\u98db\u5148\u751f\u8868\u793a\uff1a<\/b>\u300c\u5728\u77ed\u77ed\u6578\u6708\u5167\uff0c\u5229\u5384\u66ff\u5c3c\u5148\u5f8c\u7372\u6279\u4e86\u4e8c\u7dda\u548c\u4e00\u7dda\u9069\u61c9\u75c7\u3002\u4e00\u7dda\u9069\u61c9\u75c7\u7684\u7372\u6279\u4e0d\u50c5\u7d66EGFR\u7a81\u8b8a\u967d\u6027NSCLC\u60a3\u8005\u6cbb\u7642\u5e36\u4f86\u4e86\u65b0\u9078\u64c7\uff0c\u66f4\u6a19\u8a8c\u8457\u5229\u5384\u66ff\u5c3c\u9069\u61c9\u75c7\u6210\u529f\u5f9e\u5f8c\u7dda\u62d3\u5c55\u81f3\u4e00\u7dda\u60a3\u8005\uff0c\u81e8\u5e8a\u9069\u7528\u60a3\u8005\u7fa4\u9ad4\u4e0d\u65b7\u64f4\u5927\u3002\u540c\u6642\uff0c\u5967\u8cfd\u5eb7\u9084\u5728\u62d3\u5c55\u5229\u5384\u66ff\u5c3c\u806f\u5408cMET\u6291\u5236\u5291\uff08ASKC202\uff09\u806f\u5408\u7528\u85e5\u81e8\u5e8a\u8a66\u9a57\uff0c\u6cbb\u7642\u7b2c\u4e09\u4ee3 EGFR-TKI\u8010\u85e5\u7684NSCLC\u60a3\u8005\u3002\u6211\u5011\u671f\u5f85\u8207\u5408\u4f5c\u5925\u4f34\u4fe1\u9054\u751f\u7269\u651c\u624b\u4e26\u80a9\uff0c\u63a8\u52d5\u5229\u5384\u66ff\u5c3c\u52a0\u901f\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u3002\u300d<\/p>\n<p class=\"prntaj\"> <b>\u95dc\u65bcEGFR\u7a81\u8b8aNSCLC<\/b> <\/p>\n<p class=\"prntaj\">\u80ba\u764c\u662f\u5168\u7403\u767c\u75c5\u7387\u548c\u6b7b\u4ea1\u7387\u6700\u9ad8\u7684\u60e1\u6027\u816b\u7624\u4e4b\u4e00<sup>[1]<\/sup>\uff0c\u5176\u4e2dNSCLC\u662f\u6700\u5e38\u898b\u7684\u75c5\u7406\u985e\u578b\uff0c\u7d04\u5360\u6240\u6709\u80ba\u764c\u768485%\u3002\u7d0470%\u7684NSCLC\u60a3\u8005\u5728\u8a3a\u65b7\u6642\u5df2\u662f\u4e0d\u9069\u65bc\u624b\u8853\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027\u75be\u75c5\u3002EGFR\u662fNSCLC\u4e2d\u6700\u5e38\u898b\u7684\u9a45\u52d5\u57fa\u56e0\uff0c30%~50%\u7684\u4e9e\u88d4NSCLC\u60a3\u8005\u5b58\u5728EGFR\u57fa\u56e0\u7a81\u8b8a\uff0cEGFR-TKI\u662f\u8a72\u985e\u60a3\u8005\u4e00\u7dda\u6a19\u6e96\u6cbb\u7642\u63a8\u85a6\uff0c\u5176\u4e2d\u7b2c\u4e09\u4ee3EGFR-TKI\u5177\u6709\u5ee3\u6cdb\u7684\u9069\u7528\u4eba\u7fa4\u3002<\/p>\n<p class=\"prntaj\"> <b>\u95dc\u65bc\u5229\u5384\u66ff\u5c3c\u7247<\/b> <\/p>\n<p class=\"prntaj\">\u5229\u5384\u66ff\u5c3c\u662f\u5177\u6709\u81ea\u4e3b\u77e5\u8b58\u7522\u6b0a\u3001\u5168\u65b0\u5206\u5b50\u5be6\u9ad4\u3001\u6d3b\u6027\u986f\u8457\u7684\u53e3\u670d\u7684\u7b2c\u4e09\u4ee3EGFR-TKI\u3002<\/p>\n<p class=\"prntaj\">\u622a\u81f3\u76ee\u524d\uff0c\u5229\u5384\u66ff\u5c3c\u7247\uff08\u5967\u58f9\u65b0<sup>\u00ae<\/sup>\uff09\u5df2\u5728\u4e2d\u570b\u7372\u62792\u9805\u9069\u61c9\u75c7\uff1a\uff081\uff09\u65e2\u5f80\u7d93EGFR\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5291\uff08TKI\uff09\u6cbb\u7642\u6642\u6216\u6cbb\u7642\u5f8c\u51fa\u73fe\u75be\u75c5\u9032\u5c55\uff0c\u4e26\u4e14\u7d93\u6aa2\u6e2c\u78ba\u8a8d\u5b58\u5728EGFR T790M\u7a81\u8b8a\u967d\u6027\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u6210\u4eba\u60a3\u8005\u7684\u6cbb\u7642\uff1b\uff082\uff09\u5177\u6709\u8868\u76ae\u751f\u9577\u56e0\u5b50\u53d7\u9ad4\uff08EGFR\uff09\u5916\u986f\u5b50 19 \u7f3a\u5931\uff0819DEL\uff09\u6216\u5916\u986f\u5b50 21\u7f6e\u63db\u7a81\u8b8a\uff08L858R\uff09\u7684\u5c40\u90e8\u665a\u671f\u6216\u5fa9\u767c\u8f49\u79fb\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u6210\u4eba\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002<\/p>\n<p class=\"prntaj\">2024\u5e7410\u6708\uff0c\u4fe1\u9054\u751f\u7269\u8207\u5967\u8cfd\u5eb7\u5c31\u5229\u5384\u66ff\u5c3c\u7247\u5728\u4e2d\u570b\u9054\u6210\u7368\u5bb6\u5546\u696d\u5316\u5408\u4f5c\u3002<\/p>\n<p> <b>\u95dc\u65bc\u4fe1\u9054\u751f\u7269<\/b> <\/p>\n<p>\u300c\u59cb\u65bc\u4fe1\uff0c\u9054\u65bc\u884c\u300d\uff0c\u958b\u767c\u51fa\u8001\u767e\u59d3\u7528\u5f97\u8d77\u7684\u9ad8\u8cea\u91cf\u751f\u7269\u85e5\uff0c\u662f\u4fe1\u9054\u751f\u7269\u7684\u4f7f\u547d\u548c\u76ee\u6a19\u3002\u4fe1\u9054\u751f\u7269\u6210\u7acb\u65bc2011\u5e74\uff0c\u81f4\u529b\u65bc\u7814\u767c\u3001\u751f\u7522\u548c\u92b7\u552e\u816b\u7624\u3001\u81ea\u8eab\u514d\u75ab\u3001\u4ee3\u8b1d\u3001\u773c\u79d1\u7b49\u91cd\u5927\u75be\u75c5\u9818\u57df\u7684\u5275\u65b0\u85e5\u7269\uff0c\u8b93\u6211\u5011\u7684\u5de5\u4f5c\u60e0\u53ca\u66f4\u591a\u7684\u751f\u547d\u3002\u516c\u53f8\u5df2\u670915\u500b\u7522\u54c1\u7372\u5f97\u6279\u51c6\u4e0a\u5e02\uff0c\u5b83\u5011\u5206\u5225\u662f\u4fe1\u8fea\u5229\u55ae\u6297\u6ce8\u5c04\u6db2\uff08\u9054\u4f2f\u8212<sup>\u00ae<\/sup>\uff09\uff0c\u8c9d\u4f10\u73e0\u55ae\u6297\u6ce8\u5c04\u6db2\uff08\u9054\u6538\u540c<sup>\u00ae<\/sup>\uff09\uff0c\u963f\u9054\u6728\u55ae\u6297\u6ce8\u5c04\u6db2\uff08\u8607\u7acb\u4fe1<sup>\u00ae<\/sup>\uff09\uff0c\u5229\u59a5\u6614\u55ae\u6297\u6ce8\u5c04\u6db2\uff08\u9054\u4f2f\u83ef<sup>\u00ae<\/sup>\uff09\uff0c\u4f69\u7c73\u66ff\u5c3c\u7247\uff08\u9054\u4f2f\u5766<sup>\u00ae<\/sup>\uff09\uff0c\u5967\u96f7\u5df4\u66ff\u5c3c\u7247\uff08\u8010\u7acb\u514b<sup>\u00ae<\/sup>\uff09\uff0c 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Anderson 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class=\"prntaj\">\u8a73\u60c5\u8acb\u8a2a\u554f\u516c\u53f8\u7db2\u7ad9\uff1awww.innoventbio.com\u6216\u516c\u53f8\u9818\u82f1\u8cec\u865fwww.linkedin.com\/<\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"> <span class=\"prnews_span\"> <i>\u8072\u660e\uff1a<\/i> <i>1.\u4fe1\u9054\u751f\u7269\u4e0d\u63a8\u85a6\u672a\u7372\u6279\u7684\u85e5\u54c1\/\u9069\u61c9\u75c7\u7684\u4f7f\u7528\u3002<\/i> <\/span> <\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"> <span class=\"prnews_span\"> <i>2.\u96f7\u83ab\u897f\u5c24\u55ae\u6297\u6ce8\u5c04\u6db2\uff08\u5e0c\u5189\u64c7<span class=\"prnews_span\"><sup>\u00ae<\/sup><\/span>\uff09\uff0c\u585e\u666e\u66ff\u5c3c\u81a0\u56ca\uff08\u777f\u59a5<span class=\"prnews_span\"><sup>\u00ae<\/sup><\/span>\uff09\u548c\u5339\u59a5\u5e03\u66ff\u5c3c\u7247\uff08\u6377\u5e15\u529b<span class=\"prnews_span\"><sup>\u00ae<\/sup><\/span>\uff09\u7531\u79ae\u4f86\u516c\u53f8\u7814\u767c<\/i> <\/span> <\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p class=\"prntaj\"> <b>\u95dc\u65bc\u5967\u8cfd\u5eb7\u85e5\u696d<\/b> <\/p>\n<p>\u5967\u8cfd\u5eb7\u85e5\u696d\u6210\u7acb\u65bc2003\u5e74\uff0c\u662f\u4e00\u5bb6\u5275\u65b0\u8207\u7814\u767c\u9a45\u52d5\u7684\u91ab\u85e5\u88fd\u9020\u4f01\u696d\u3002\u516c\u53f8\u81ea\u4e3b\u7814\u767c\u4e86\u4e2d\u570b\u7b2c\u4e00\u652f\u570b\u7522\u5316\u8cea\u5b50\u6cf5\u6291\u5236\u5291\uff08PPI\uff09\u6ce8\u5c04\u5291\uff0c\u7d93\u4e8c\u5341\u591a\u5e74\u7684\u767c\u5c55\uff0c\u85e5\u7269\u6cbb\u7642\u9818\u57df\u5df2\u8986\u84cb\u6d88\u5316\u3001\u6297\u816b\u7624\u3001\u6297\u611f\u67d3\u548c\u6162\u6027\u75c5\u56db\u5927\u9818\u57df\u3002\u5728\u4e2d\u570b\u91ab\u85e5\u7d30\u5206\u5e02\u5834\u5177\u6709\u8f03\u9ad8\u7684\u54c1\u724c\u5f71\u97ff\u529b\u3002<\/p>\n<p>\u5967\u8cfd\u5eb7\u85e5\u696d\u901a\u904e\u81ea\u4e3b\u7814\u767c\u8207\u5f15\u9032\u5408\u4f5c\u96d9\u5411\u767c\u529b\uff0c\u91cd\u9ede\u805a\u7126\u5c0f\u5206\u5b50\u9776\u5411\u5275\u65b0\u85e5\u548c\u816b\u7624\u514d\u75ab\u751f\u7269\u5275\u65b0\u85e5\u7684\u7814\u767c\u3002\u76ee\u524d\u4e3b\u8981\u5728\u7814\u9805\u76ee\u5171\u8a0848\u9805\uff0c\u5305\u62ec\u5df2\u516c\u958b\u768410\u9805\u91cd\u9ede\u5728\u7814\u5316\u5b78\u3001\u751f\u7269\u5275\u65b0\u85e5\u3002\u5176\u4e2dASKC109\uff08\u9ea5\u82bd\u915a\u9435\u81a0\u56ca\uff09\u3001ASKB589\uff08Claudin18.2\u55ae\u6297\uff09\u8655\u65bc\u81e8\u5e8aIII\u671f\u7814\u7a76\u968e\u6bb5\uff0c\u53e6\u6709\u591a\u6b3e\u5275\u65b0\u85e5\u8655\u65bc\u65e9\u671f\u81e8\u5e8a\u53ca\u81e8\u5e8a\u524d\u7814\u7a76\u968e\u6bb5\u3002<\/p>\n<p>\u5967\u8cfd\u5eb7\u85e5\u696d\u79c9\u6301\u300c\u70ba\u5065\u5eb7 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(a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002<\/p>\n<p> <i>\u53c3\u8003\u6587\u737b<\/i> <\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"> <span class=\"prnews_span\">[1] Bray F, et al. Global cancer statistics 2022. CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322\/caac.21834. Epub 2024 Apr 4. PMID: 38572751.<\/span> <\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>\u00a0<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde 2025&#8230;<\/p>\n","protected":false},"author":16,"featured_media":199219,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-316986","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u4fe1\u9054\u751f\u7269\u5ba3\u4f48\u8207\u5967\u8cfd\u5eb7\u5408\u4f5c\u7684\u7b2c\u4e09\u4ee3EGFR TKI 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\u9019\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u4e43\u57fa\u65bc\u672c\u516c\u53f8\u7ba1\u7406\u5c64\u5728\u505a\u51fa\u8868\u8ff0\u6642\u5c0d\u672a\u4f86\u4e8b\u52d9\u7684\u73fe\u6709\u770b\u6cd5\u3001\u5047\u8a2d\u3001\u671f\u671b\u3001\u4f30\u8a08\u3001\u9810\u6e2c\u548c\u7406\u89e3\u3002\u9019\u4e9b\u8868\u8ff0\u4e26\u975e\u5c0d\u672a\u4f86\u767c\u5c55\u7684\u4fdd\u8b49\uff0c\u6703\u53d7\u5230\u98a8\u96aa\u3001\u4e0d\u78ba\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u97ff\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u7bc4\u570d\uff0c\u96e3\u4ee5\u9810\u8a08\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u5011\u7684\u696d\u52d9\u3001\u7af6\u722d\u74b0\u5883\u3001\u653f\u6cbb\u3001\u7d93\u6fdf\u3001\u6cd5\u5f8b\u548c\u793e\u6703\u60c5\u6cc1\u7684\u672a\u4f86\u8b8a\u5316\u53ca\u767c\u5c55\u7684\u5f71\u97ff\uff0c\u5be6\u969b\u7d50\u679c\u53ef\u80fd\u6703\u8207\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8cc7\u6599\u6709\u8f03\u5927\u5dee\u5225\u3002 \u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u50f1\u54e1\u4ee3\u7406\u6982\u4e0d\u627f\u64d4 (a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002  \u53c3\u8003\u6587\u737b            Bray F, et al. Global cancer statistics 2022. CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322\/caac.21834. Epub 2024 Apr 4. PMID: 38572751.         \u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=316986\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u4fe1\u9054\u751f\u7269\u5ba3\u4f48\u8207\u5967\u8cfd\u5eb7\u5408\u4f5c\u7684\u7b2c\u4e09\u4ee3EGFR TKI \u80ba\u764c\u9776\u5411\u85e5\u7269\u5967\u58f9\u65b0\u00ae\uff08\u5229\u5384\u66ff\u5c3c\u7247\uff09\u4e00\u7dda\u9069\u61c9\u75c7\u7372\u6279\u4e0a\u5e02 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde 2025\u5e744\u670826\u65e5 \/\u7f8e\u901a\u793e\/ -- 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\u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u50f1\u54e1\u4ee3\u7406\u6982\u4e0d\u627f\u64d4 (a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002  \u53c3\u8003\u6587\u737b            Bray F, et al. Global cancer statistics 2022. CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322\/caac.21834. Epub 2024 Apr 4. 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Global cancer statistics 2022. CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322\\\/caac.21834. Epub 2024 Apr 4. 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Global cancer statistics 2022. CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322\/caac.21834. Epub 2024 Apr 4. PMID: 38572751.         \u00a0","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pingtungtimes.com.tw\/?p=316986","og_locale":"zh_TW","og_type":"article","og_title":"\u4fe1\u9054\u751f\u7269\u5ba3\u4f48\u8207\u5967\u8cfd\u5eb7\u5408\u4f5c\u7684\u7b2c\u4e09\u4ee3EGFR TKI \u80ba\u764c\u9776\u5411\u85e5\u7269\u5967\u58f9\u65b0\u00ae\uff08\u5229\u5384\u66ff\u5c3c\u7247\uff09\u4e00\u7dda\u9069\u61c9\u75c7\u7372\u6279\u4e0a\u5e02 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","og_description":"\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde 2025\u5e744\u670826\u65e5 \/\u7f8e\u901a\u793e\/ -- 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Global cancer statistics 2022. CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322\/caac.21834. Epub 2024 Apr 4. 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Global cancer statistics 2022. CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322\/caac.21834. Epub 2024 Apr 4. 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