{"id":283550,"date":"2024-12-13T07:20:00","date_gmt":"2024-12-12T23:20:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=283550"},"modified":"2024-12-13T07:20:00","modified_gmt":"2024-12-12T23:20:00","slug":"%e7%b6%ad%e8%bf%aa%e8%a5%bf%e5%a6%a5%e5%96%ae%e6%8a%97%e6%b2%bb%e7%99%82her2%e9%99%bd%e6%80%a7%e5%ad%98%e5%9c%a8%e8%82%9d%e8%bd%89%e7%a7%bb%e7%9a%84%e6%99%9a%e6%9c%9f%e4%b9%b3%e8%85%ba%e7%99%8c","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=283550","title":{"rendered":"\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u6cbb\u7642HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005III\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\u516c\u5e03\uff5c2024 SABCS"},"content":{"rendered":"<div>\n<table name=\"logo_release\" border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legendSpanClass\">\u7159\u53f0<\/span><span 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\u300c\u9019\u662f\u7b2c\u4e00\u500b\u8b49\u5be6HER2\u9776\u5411ADC\u5728HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u4e2d\u5177\u6709\u986f\u8457\u7642\u6548\u7684\u2162\u671f\u78ba\u8b49\u6027\u7814\u7a76\u3002\u300d\u738b\u4f73\u7389\u6559\u6388\u8868\u793a\uff0c\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u5c0d\u6bd4\u62c9\u5e15\u66ff\u5c3c\u806f\u5408\u5361\u57f9\u4ed6\u6ff1\u6539\u5584\u4e86\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\uff0c\u4e14\u986f\u793a\u51fa\u826f\u597d\u7684\u751f\u5b58\u7372\u76ca\u8da8\u52e2\uff0c\u5b89\u5168\u6027\u53ef\u63a7\uff0c\u6709\u671b\u70ba\u65e2\u5f80\u63a5\u53d7\u904e\u66f2\u59a5\u73e0\u55ae\u6297\u548c\u7d2b\u6749\u9187\u6cbb\u7642\u7684HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u63d0\u4f9b\u66f4\u7cbe\u51c6\u3001\u5f37\u6548\u3001\u5b89\u5168\u7684\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002 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content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u6cbb\u7642HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005III\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\u516c\u5e03\uff5c2024 SABCS - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u7159\u53f02024\u5e7412\u670813\u65e5 \/\u7f8e\u901a\u793e\/ -- \u7576\u5730\u6642\u959312\u670812\u65e5\u4e0a\u5348\uff0c\u5728\u7b2c47\u5c46\u8056\u5b89\u6771\u5c3c\u5967\u4e73\u817a\u764c\u7814\u8a0e\u6703\uff08SABCS\uff09\u300c\u65b0\u578bHER2\u7642\u6cd5\u300d\u7684\u91cd\u8981\u58c1\u5831\u5c08\u5834\uff08Poster Spotlight Sessions\uff09\uff0c\u69ae\u660c\u751f\u7269\u9996\u6b21\u5c0d\u5916\u516c\u5e03\u4e86\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u6cbb\u7642HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u2162\u671f\u81e8\u5e8a\u7814\u7a76\u6578\u64da\uff0c\u9019\u662f\u5168\u7403\u9996\u500b\u8b49\u5be6HER2 ADC\u5728HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u4e2d\u53d6\u5f97\u967d\u6027\u7d50\u679c\u7684\u78ba\u8b49\u6027\u2162\u671f\u7814\u7a76\uff0c\u4e2d\u570b\u91ab\u5b78\u79d1\u5b78\u9662\u816b\u7624\u91ab\u9662\u738b\u4f73\u7389\u6559\u6388\u4f5c\u532f\u5831\u8a0e\u8ad6\u3002SABCS\u662f\u4e73\u817a\u764c\u7814\u7a76\u9818\u57df\u898f\u6a21\u6700\u5927\u3001\u6700\u5177\u5f71\u97ff\u529b\u7684\u5e74\u5ea6\u76db\u6703\u4e4b\u4e00\uff0c\u6b64\u9805\u91cd\u78c5\u7814\u7a76\u6210\u679c\u7684\u516c\u5e03\u5438\u5f15\u4e86\u5168\u7403\u5c08\u5bb6\u5b78\u8005\u7684\u95dc\u6ce8\u3002     \u6578\u64da\u986f\u793a\uff0c\u7d0445%\u7684HER2\u967d\u6027\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u4f34\u6709\u809d\u8f49\u79fb\uff0c\u9810\u5f8c\u8f03\u5dee\uff0c5\u5e74\u751f\u5b58\u7387\u50c5\u70ba8%~12%\u3002 \u6b64\u6b21\u516c\u5e03\u7684\u662f\u4e00\u9805\u96a8\u6a5f\u3001\u958b\u653e\u3001\u591a\u4e2d\u5fc3\u7684\u2162\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u8a55\u50f9\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u5c0d\u6bd4\u62c9\u5e15\u66ff\u5c3c\u806f\u5408\u5361\u57f9\u4ed6\u6ff1\u6cbb\u7642HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u5171\u7d0d\u5165\u4e86104\u540d\u60a3\u8005\uff0c\u65e2\u5f80\u5747\u63a5\u53d7\u904e\u66f2\u59a5\u73e0\u55ae\u6297\u548c\u7d2b\u6749\u9187\u6cbb\u7642\u3002 \u622a\u81f32023\u5e7412\u670831\u65e5\uff08\u4e2d\u4f4d\u96a8\u8a2a17.2\u500b\u6708\uff09\uff0c\u6b64\u7814\u7a76\u6700\u7d42\u5206\u6790\u7d50\u679c\u986f\u793a\uff1a   \u6839\u64da\u7368\u7acb\u5be9\u67e5\u59d4\u54e1\u6703\uff08IRC\uff09\u8a55\u4f30\uff0c\u8207\u62c9\u5e15\u66ff\u5c3c\u806f\u5408\u5361\u57f9\u4ed6\u6ff1\u76f8\u6bd4\uff0c\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u986f\u8457\u5ef6\u9577\u4e86\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\uff0c\u75be\u75c5\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u4e8644%\u3002\u4e2d\u4f4dPFS\u5206\u5225\u70ba9.9vs4.9\u500b\u6708\uff0c\u98a8\u96aa\u6bd4=0.56 \uff09\uff0c\u96d9\u5074P=0.0143\u3002\u5b89\u5168\u6027\u6578\u64da\u8207\u5df2\u77e5\u98a8\u96aa\u76f8\u4f3c\uff0c\u5b89\u5168\u6027\u53ef\u63a7\u3002  \u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u6578\u64da\u5c1a\u4e0d\u6210\u719f\uff0c\u96d6\u7136\u62c9\u5e15\u66ff\u5c3c\u806f\u5408\u5361\u57f9\u4ed6\u6ff1\u7d44\u670921\u4f8b\u60a3\u8005\u75be\u75c5\u9032\u5c55\u5f8c\u63a5\u53d7\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u6cbb\u7642\uff0c\u4f46\u5df2\u89c0\u5bdf\u5230\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u7d44\u6709\u660e\u986f\u7684\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u7372\u76ca\u8da8\u52e2\uff0c\u5169\u7d44\u4e2d\u4f4dOS\u5206\u5225\u70baNE vs 25.92\u500b\u6708\uff08HR=0.56, 95%CI: 0.25-1.29\uff09\u3002  \u300c\u9019\u662f\u7b2c\u4e00\u500b\u8b49\u5be6HER2\u9776\u5411ADC\u5728HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u4e2d\u5177\u6709\u986f\u8457\u7642\u6548\u7684\u2162\u671f\u78ba\u8b49\u6027\u7814\u7a76\u3002\u300d\u738b\u4f73\u7389\u6559\u6388\u8868\u793a\uff0c\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u5c0d\u6bd4\u62c9\u5e15\u66ff\u5c3c\u806f\u5408\u5361\u57f9\u4ed6\u6ff1\u6539\u5584\u4e86\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\uff0c\u4e14\u986f\u793a\u51fa\u826f\u597d\u7684\u751f\u5b58\u7372\u76ca\u8da8\u52e2\uff0c\u5b89\u5168\u6027\u53ef\u63a7\uff0c\u6709\u671b\u70ba\u65e2\u5f80\u63a5\u53d7\u904e\u66f2\u59a5\u73e0\u55ae\u6297\u548c\u7d2b\u6749\u9187\u6cbb\u7642\u7684HER2\u967d\u6027\u5b58\u5728\u809d\u8f49\u79fb\u7684\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u63d0\u4f9b\u66f4\u7cbe\u51c6\u3001\u5f37\u6548\u3001\u5b89\u5168\u7684\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002 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\u6839\u64da\u7368\u7acb\u5be9\u67e5\u59d4\u54e1\u6703\uff08IRC\uff09\u8a55\u4f30\uff0c\u8207\u62c9\u5e15\u66ff\u5c3c\u806f\u5408\u5361\u57f9\u4ed6\u6ff1\u76f8\u6bd4\uff0c\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u986f\u8457\u5ef6\u9577\u4e86\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\uff0c\u75be\u75c5\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u4e8644%\u3002\u4e2d\u4f4dPFS\u5206\u5225\u70ba9.9vs4.9\u500b\u6708\uff0c\u98a8\u96aa\u6bd4=0.56 \uff09\uff0c\u96d9\u5074P=0.0143\u3002\u5b89\u5168\u6027\u6578\u64da\u8207\u5df2\u77e5\u98a8\u96aa\u76f8\u4f3c\uff0c\u5b89\u5168\u6027\u53ef\u63a7\u3002  \u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u6578\u64da\u5c1a\u4e0d\u6210\u719f\uff0c\u96d6\u7136\u62c9\u5e15\u66ff\u5c3c\u806f\u5408\u5361\u57f9\u4ed6\u6ff1\u7d44\u670921\u4f8b\u60a3\u8005\u75be\u75c5\u9032\u5c55\u5f8c\u63a5\u53d7\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u6cbb\u7642\uff0c\u4f46\u5df2\u89c0\u5bdf\u5230\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u7d44\u6709\u660e\u986f\u7684\u7e3d\u751f\u5b58\u671f\uff08OS\uff09\u7372\u76ca\u8da8\u52e2\uff0c\u5169\u7d44\u4e2d\u4f4dOS\u5206\u5225\u70baNE vs 25.92\u500b\u6708\uff08HR=0.56, 95%CI: 0.25-1.29\uff09\u3002  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\u6839\u64da\u7368\u7acb\u5be9\u67e5\u59d4\u54e1\u6703\uff08IRC\uff09\u8a55\u4f30\uff0c\u8207\u62c9\u5e15\u66ff\u5c3c\u806f\u5408\u5361\u57f9\u4ed6\u6ff1\u76f8\u6bd4\uff0c\u7dad\u8fea\u897f\u59a5\u55ae\u6297\u986f\u8457\u5ef6\u9577\u4e86\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\uff0c\u75be\u75c5\u9032\u5c55\u6216\u6b7b\u4ea1\u98a8\u96aa\u964d\u4f4e\u4e8644%\u3002\u4e2d\u4f4dPFS\u5206\u5225\u70ba9.9vs4.9\u500b\u6708\uff0c\u98a8\u96aa\u6bd4=0.56 \uff09\uff0c\u96d9\u5074P=0.0143\u3002\u5b89\u5168\u6027\u6578\u64da\u8207\u5df2\u77e5\u98a8\u96aa\u76f8\u4f3c\uff0c\u5b89\u5168\u6027\u53ef\u63a7\u3002  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