{"id":272717,"date":"2024-10-31T13:00:00","date_gmt":"2024-10-31T05:00:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=272717"},"modified":"2024-10-31T13:00:00","modified_gmt":"2024-10-31T05:00:00","slug":"%e5%9c%8b%e7%94%a2pd-l1%e9%a6%96%e5%ba%a6%e5%9c%a8%e8%8b%b1%e5%9c%8b%e7%8d%b2%e6%89%b9%ef%bc%81%e5%9f%ba%e7%9f%b3%e8%97%a5%e6%a5%ad%e5%ae%a3%e5%b8%83%e8%88%92%e6%a0%bc%e5%88%a9%e5%96%ae%e6%8a%97","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=272717","title":{"rendered":"\u570b\u7522PD-L1\u9996\u5ea6\u5728\u82f1\u570b\u7372\u6279\uff01\u57fa\u77f3\u85e5\u696d\u5ba3\u5e03\u8212\u683c\u5229\u55ae\u6297\u7372\u82f1\u570b\u85e5\u54c1\u548c\u91ab\u7642\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\u6279\u51c6 \u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u975e\u5c0f\u7d30\u80de\u80ba\u764c"},"content":{"rendered":"<div>\n<ul type=\"disc\">\n<li>\u9019\u662f\u7e7c\u6b50\u76df\u59d4\u54e1\u6703\u6279\u51c6\u5f8c\uff0c\u8212\u683c\u5229\u55ae\u6297\u5728\u4e2d\u570b\u5883\u5916\u7372\u5f97\u7684\u7b2c\u4e8c\u9805\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u7684\u6279\u51c6\u3002<\/li>\n<li>\u6b64\u6b21\u6279\u51c6\u662f\u57fa\u65bc\u8212\u683c\u5229\u55ae\u6297III\u671f\u81e8\u5e8a\u7814\u7a76GEMSTONE-302\u7684\u7d50\u679c\uff0c\u8a72\u7814\u7a76\u5df2\u8b49\u660e\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u53ef\u986f\u8457\u5ef6\u9577\u521d\u6cbb\u8f49\u79fb\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\u548c\u7e3d\u751f\u5b58\u671f\u3002<\/li>\n<li>GEMSTONE-302\u7814\u7a76\u7684\u9577\u671f\u6cbb\u7642\u548c\u751f\u5b58\u6578\u64da\u5df2\u57282024\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\uff08ESMO\uff09\u5e74\u6703\u4e0a\u516c\u5e03\u3002<\/li>\n<li>\u8212\u683c\u5229\u55ae\u6297\u5176\u4ed6\u9069\u61c9\u75c7\u5728\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u7b49\u76e3\u7ba1\u6a5f\u69cb\u7684\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u6b63\u5728\u9032\u884c\u4e2d\u3002<\/li>\n<li>\u57fa\u77f3\u85e5\u696d\u5df2\u8207Ewopharma\u9054\u6210\u8212\u683c\u5229\u55ae\u6297\u5728\u4e2d\u6b50\u3001\u6771\u6b50\u548c\u745e\u58eb\u7684\u5546\u696d\u5316\u6230\u7565\u5408\u4f5c\uff0c\u9810\u8a08\u8fd1\u671f\u5c07\u5728\u897f\u6b50\u3001\u62c9\u4e01\u7f8e\u6d32\u3001\u4e2d\u6771\u3001\u6771\u5357\u4e9e\u7b49\u5730\u5340\u9054\u6210\u66f4\u591a\u7684\u5546\u696d\u5408\u4f5c\u5354\u8b70\u3002<\/li>\n<\/ul>\n<p id=\"temp_ReleaseStart\"><span class=\"legendSpanClass\">\u4e2d\u570b\u8607\u5dde<\/span><span class=\"legendSpanClass\">2024\u5e7410\u670831\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u57fa\u77f3\u85e5\u696d\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc\uff1a2616\uff09\uff0c\u4e00\u5bb6\u5c08\u6ce8\u65bc\u6297\u816b\u7624\u85e5\u7269\u7814\u767c\u7684\u5275\u65b0\u9a45\u52d5\u578b\u751f\u7269\u91ab\u85e5\u4f01\u696d\uff0c\u4eca\u65e5\u5ba3\u5e03\uff0c\u82f1\u570b\u85e5\u54c1\u548c\u91ab\u7642\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\uff08MHRA\uff09\u5df2\u6279\u51c6\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u542b\u9251\u5316\u7642\u7528\u65bc\u7121EGFR\u654f\u611f\u7a81\u8b8a, \u6216\u7121ALK, ROS1, RET\u57fa\u56e0\u7d44\u816b\u7624\u8b8a\u7570\u7684\u8f49\u79fb\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u6210\u4eba\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002\u9019\u662f\u7e7c\u6b50\u76df\u59d4\u54e1\u6703\u6279\u51c6\u4e4b\u5f8c\uff0c\u8212\u683c\u5229\u55ae\u6297\u5728\u6d77\u5916\u5e02\u5834\u7372\u5f97\u7684\u7b2c\u4e8c\u9805\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u7684\u6279\u51c6\u3002<\/p>\n<p class=\"prntaj\">\u57fa\u77f3\u85e5\u696d\u9996\u5e2d\u57f7\u884c\u5b98\u3001\u7814\u767c\u7e3d\u88c1\u3001\u57f7\u884c\u8463\u4e8b\u694a\u5efa\u65b0\u535a\u58eb\u8868\u793a\uff1a\u300c\u8212\u683c\u5229\u55ae\u6297\u5728\u82f1\u570b\u7372\u6279\uff0c\u6a19\u5fd7\u8457\u6211\u5011\u5168\u7403\u5316\u5e03\u5c40\u7684\u53c8\u4e00\u91cd\u8981\u88e1\u7a0b\u7891\u3002\u8212\u683c\u5229\u55ae\u6297\u662f\u9996\u500b\u6210\u529f\u51fa\u6d77\u7684\u570b\u7522PD-L1\u55ae\u6297\uff0c\u5728\u767b\u9678\u5168\u7403\u7b2c\u4e8c\u5927\u91ab\u85e5\u5e02\u5834\u2014\u2014\u6b50\u76df\u4e4b\u5f8c\uff0c\u8212\u683c\u5229\u300e\u518d\u4e0b\u4e00\u57ce\u300f\uff0c\u62ff\u5230\u82f1\u570b\u9019\u4e00\u91cd\u8981\u6d77\u5916\u5e02\u5834\u7684\u300e\u5165\u5834\u5238\u300f\u3002\u5728\u4eca\u5e74ESMO\u4e0a\u516c\u5e03\u7684\u9577\u671f\u751f\u5b58\u6578\u64da\uff0c\u66f4\u662f\u9032\u4e00\u6b65\u978f\u56fa\u4e86\u8212\u683c\u5229\u55ae\u6297\u5728\u8f49\u79fb\u6027NSCLC\u4e00\u7dda\u6cbb\u7642\u683c\u5c40\u4e2d\u7684\u91cd\u8981\u5730\u4f4d\u3002\u300d<\/p>\n<p class=\"prntaj\">\u694a\u535a\u58eb\u88dc\u5145\u9053\uff1a\u300c\u6d77\u5916\u5546\u696d\u5316\u548c\u6ce8\u518a\u65b9\u9762\uff0c\u6211\u5011\u6b63\u7a4d\u6975\u8207\u4f86\u81ea\u897f\u6b50\u3001\u62c9\u7f8e\u3001\u4e2d\u6771\u3001\u6771\u5357\u4e9e\u3001\u52a0\u62ff\u5927\u7b49\u5730\u5340\u7684\u5408\u4f5c\u4f19\u4f34\u6d3d\u8ac7\uff0c\u9810\u8a08\u8fd1\u671f\u5c07\u9054\u6210\u5176\u4e2d\u591a\u9805\u5546\u696d\u5408\u4f5c\u3002\u540c\u6642\uff0c\u6211\u5011\u5728\u7a4d\u6975\u8207\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u7b49\u570b\u969b\u76e3\u7ba1\u6a5f\u69cb\u6e9d\u901a\u8212\u683c\u5229\u55ae\u6297\u5176\u4ed6\u9069\u61c9\u75c7\uff0c\u5982III\u671fNSCLC\u3001\u4e00\u7dda\u80c3\u764c\u3001\u4e00\u7dda\u98df\u7ba1\u9c57\u764c\u7684\u4e0a\u5e02\u7533\u8acb\uff0c\u671f\u5f85\u70ba\u5168\u7403\u66f4\u591a\u60a3\u8005\u5e36\u4f86\u5275\u65b0\u7684\u6cbb\u7642\u65b9\u6848\u3002\u300d<\/p>\n<p class=\"prntaj\">\u6b64\u6b21\u7372\u6279\u4e3b\u8981\u662f\u57fa\u65bc\u4e00\u9805\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u96d9\u76f2\u7684III\u671f\u81e8\u5e8a\u7814\u7a76\u2014\u2014GEMSTONE-302\u7684\u7d50\u679c\u3002\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u5c0d\u6bd4\u5b89\u6170\u5291\u806f\u5408\u5316\u7642\uff0c\u53ef\u986f\u8457\u5ef6\u9577\u521d\u6cbb\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\u548c\u7e3d\u751f\u5b58\u671f\u3002\u8a72\u7814\u7a76\u6578\u64da\u5df2\u5728\u300a\u67f3\u8449\u5200\u00b7\u816b\u7624\u5b78\u300b\uff08Lancet Oncology\uff09\u548c\u300a\u81ea\u7136\u00b7\u764c\u75c7\u300b\uff08Nature Cancer\uff09\u4e0a\u767c\u8868\uff0c\u4e26\u66fe\u591a\u6b21\u5728\u570b\u969b\u5b78\u8853\u6703\u8b70\u4e0a\u4ee5\u53e3\u982d\u532f\u5831\u548c\u58c1\u5831\u5f62\u5f0f\u516c\u5e03\u3002<\/p>\n<p class=\"prntaj\"><b>\u95dc\u65bc\u8212\u683c\u5229\u55ae\u6297\u6ce8\u5c04\u6db2<\/b><\/p>\n<p class=\"prntaj\">\u8212\u683c\u5229\u55ae\u6297\u662f\u7531\u57fa\u77f3\u85e5\u696d\u7814\u767c\u7684\u6297PD-L1\u55ae\u514b\u9686\u6297\u9ad4\uff0c\u8212\u683c\u5229\u55ae\u6297\u7684\u958b\u767c\u662f\u57fa\u65bc\u7f8e\u570bLigand\u516c\u53f8\u6388\u6b0a\u5f15\u9032\u7684OmniRat<sup>\u00ae<\/sup>\u8f49\u57fa\u56e0\u52d5\u7269\u5e73\u53f0\u3002\u8a72\u5e73\u53f0\u53ef\u4e00\u7ad9\u5f0f\u7522\u751f\u5168\u4eba\u6e90\u6297\u9ad4\u3002\u4f5c\u70ba\u4e00\u7a2e\u5168\u4eba\u6e90\u5168\u9577\u6297PD-L1\u55ae\u514b\u9686\u6297\u9ad4\uff0c\u8212\u683c\u5229\u55ae\u6297\u662f\u4e00\u7a2e\u6700\u63a5\u8fd1\u4eba\u9ad4\u7684\u5929\u7136G\u578b\u514d\u75ab\u7403\u86cb\u767d4\uff08IgG4\uff09\u55ae\u6297\u85e5\u7269\uff0c\u80fd\u964d\u4f4e\u5728\u60a3\u8005\u9ad4\u5167\u7522\u751f\u514d\u75ab\u539f\u6027\u53ca\u76f8\u95dc\u6bd2\u6027\u7684\u6f5b\u5728\u98a8\u96aa\uff0c\u8207\u540c\u985e\u85e5\u7269\u76f8\u6bd4\u8212\u683c\u5229\u55ae\u6297\u5c07\u5177\u6709\u7368\u7279\u512a\u52e2\u3002\u8212\u683c\u5229\u55ae\u6297\u7368\u7279\u5206\u5b50\u8a2d\u8a08\u4f7f\u5176\u5177\u5099\u96d9\u91cd\u4f5c\u7528\u6a5f\u5236\uff0c\u4e0d\u50c5\u963b\u65b7PD-1\/PD-L1\u76f8\u4e92\u4f5c\u7528\uff0c\u9084\u80fd\u901a\u904e\u4ecb\u5c0ePD-L1\u8868\u9054\u967d\u6027\u7684\u816b\u7624\u7d30\u80de\u8207\u816b\u7624\u76f8\u95dc\u5de8\u566c\u7d30\u80de\uff08TAMs\uff09\uff0c\u5728\u8a98\u5c0e\u6297\u9ad4\u4f9d\u8cf4\u6027\u7d30\u80de\u541e\u566c\uff08ADCP\uff09\u7684\u540c\u6642\u4e0d\u640d\u5bb3\u6548\u61c9\u6027T\u7d30\u80de\u3002\u9019\u7a2e\u5dee\u7570\u5316\u8a2d\u8a08\u4f7f\u8212\u683c\u5229\u55ae\u6297\u5728\u4e0d\u540c\u985e\u578b\u7684\u816b\u7624\u4e2d\u5c55\u73fe\u51fa\u4e86\u6f5b\u5728\u540c\u985e\u6700\u512a\u7684\u7642\u6548\u548c\u5b89\u5168\u6027\u3002<\/p>\n<p class=\"prntaj\">\u76ee\u524d\uff0c\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u5df2\u6279\u51c6\u8212\u683c\u5229\u55ae\u6297\uff08\u5546\u54c1\u540d\uff1a\u64c7\u6377\u7f8e<sup>\u00ae<\/sup>\uff09\u4e94\u9805\u9069\u61c9\u75c7\uff1a<\/p>\n<ul type=\"disc\">\n<li>\u806f\u5408\u5316\u7642\u4e00\u7dda\u6cbb\u7642\u8f49\u79fb\u6027\u9c57\u72c0\u548c\u975e\u9c57\u72c0NSCLC\u60a3\u8005\uff1b<\/li>\n<li>\u6cbb\u7642\u540c\u6b65\u6216\u5e8f\u8cab\u653e\u5316\u7642\u5f8c\u672a\u51fa\u73fe\u75be\u75c5\u9032\u5c55\u7684\u3001\u4e0d\u53ef\u5207\u9664\u3001III\u671fNSCLC\u60a3\u8005\uff1b<\/li>\n<li>\u6cbb\u7642\u5fa9\u767c\u6216\u96e3\u6cbb\u6027\u7d50\u5916NK\/T\u7d30\u80de\u6dcb\u5df4\u7624\u60a3\u8005\uff1b<\/li>\n<li>\u806f\u5408\u6c1f\u5c3f\u5627\u5576\u985e\u548c\u9251\u985e\u5316\u7642\u85e5\u7269\u4e00\u7dda\u6cbb\u7642\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\uff0c\u5fa9\u767c\u6216\u8f49\u79fb\u6027\u98df\u7ba1\u9c57\u764c\u60a3\u8005\uff1b<\/li>\n<li>\u806f\u5408\u542b\u6c1f\u5c3f\u5627\u5576\u985e\u548c\u9251\u985e\u85e5\u7269\u5316\u7642\u7528\u65bc\u8868\u9054PD-L1\uff08\u7d9c\u5408\u967d\u6027\u8a55\u5206[CPS]\u22655\uff09\u7684\u4e0d\u53ef\u624b\u8853\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027\u80c3\u53ca\u80c3\u98df\u7ba1\u7d50\u5408\u90e8\u817a\u764c\u7684\u4e00\u7dda\u6cbb\u7642\u3002<\/li>\n<\/ul>\n<p class=\"prntaj\">\u6b50\u76df\u59d4\u54e1\u6703\uff08EC\uff09\u5df2\u6279\u51c6\u8212\u683c\u5229\u55ae\u6297\uff08\u5546\u54c1\u540d\uff1aCejemly<sup>\u00ae<\/sup>\uff09\u806f\u5408\u542b\u9251\u5316\u7642\u7528\u65bc\u7121EGFR\u654f\u611f\u7a81\u8b8a, \u6216\u7121ALK, ROS1, RET\u57fa\u56e0\u7d44\u816b\u7624\u8b8a\u7570\u7684\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002<\/p>\n<p class=\"prntaj\">\u82f1\u570b\u85e5\u54c1\u548c\u91ab\u7642\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\uff08MHRA\uff09\u5df2\u6279\u51c6\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u542b\u9251\u5316\u7642\u7528\u65bc\u7121EGFR\u654f\u611f\u7a81\u8b8a, \u6216\u7121ALK, ROS1, RET\u57fa\u56e0\u7d44\u816b\u7624\u8b8a\u7570\u7684\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002<\/p>\n<p class=\"prntaj\"><b>\u95dc\u65bc\u57fa\u77f3\u85e5\u696d<\/b><\/p>\n<p class=\"prntaj\">\u57fa\u77f3\u85e5\u696d\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc: 2616\uff09\u6210\u7acb\u65bc2015\u5e74\u5e95\uff0c\u662f\u4e00\u5bb6\u5c08\u6ce8\u65bc\u6297\u816b\u7624\u85e5\u7269\u7814\u767c\u7684\u5275\u65b0\u9a45\u52d5\u578b\u751f\u7269\u91ab\u85e5\u4f01\u696d\uff0c\u81f4\u529b\u65bc\u6eff\u8db3\u4e2d\u570b\u548c\u5168\u7403\u764c\u75c7\u60a3\u8005\u7684\u6bb7\u5207\u91ab\u7642\u9700\u6c42\u3002\u622a\u81f3\u76ee\u524d\uff0c\u516c\u53f8\u5df2\u6210\u529f\u4e0a\u5e024\u6b3e\u5275\u65b0\u85e5\u3001\u7372\u627916\u9805\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\u4ee5\u53ca9\u9805\u9069\u61c9\u75c7\u3002\u7576\u524d\u7814\u767c\u7ba1\u7dda\u5747\u8861\u914d\u7f6e\u4e86\u6f5b\u5728\u540c\u985e\u9996\u5275\u6216\u540c\u985e\u6700\u4f73\u7684\u6297\u9ad4\u5076\u806f\u85e5\u7269\uff08ADC\uff09\u3001\u591a\u7279\u7570\u6027\u6297\u9ad4\u3001\u4ee5\u53ca\u514d\u75ab\u7642\u6cd5\u548c\u7cbe\u51c6\u6cbb\u7642\u85e5\u7269\u5728\u5167\u768416\u6b3e\u5019\u9078\u85e5\u7269\u3002\u540c\u6642\uff0c\u57fa\u77f3\u85e5\u696d\u64c1\u6709\u4e00\u652f\u8cc7\u6df1\u7ba1\u7406\u5718\u968a\uff0c\u300c\u5168\u93c8\u689d\u300d\u8986\u84cb\u81e8\u5e8a\u524d\u63a2\u7d22\u3001\u81e8\u5e8a\u8f49\u5316\u3001\u81e8\u5e8a\u958b\u767c\u3001\u85e5\u7269\u751f\u7522\u3001\u5546\u52d9\u62d3\u5c55\u3001\u5546\u696d\u904b\u71df\u7b49\u95dc\u9375\u74b0\u7bc0\u3002<\/p>\n<p class=\"prntaj\">\u5982\u9700\u4e86\u89e3\u6709\u95dc\u57fa\u77f3\u85e5\u696d\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\uff1a<a href=\"http:\/\/www.cstonepharma.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.cstonepharma.com<\/a>\u3002<br \/>\u6295\u8cc7\u8005\u95dc\u7cfb: <a href=\"mailto:ir@cstonepharma.com\" target=\"_blank\" rel=\"nofollow noopener\">ir@cstonepharma.com<\/a><br \/>\u5a92\u9ad4\u95dc\u7cfb: <a href=\"mailto:pr@cstonepharma.com\" target=\"_blank\" rel=\"nofollow noopener\">pr@cstonepharma.com<\/a><\/p>\n<p class=\"prntaj\"><b>\u524d\u77bb\u6027\u8072\u660e<\/b><\/p>\n<p class=\"prntaj\">\u672c\u6587\u6240\u4f5c\u51fa\u7684\u524d\u77bb\u6027\u9673\u8ff0\u50c5\u8207\u672c\u6587\u4f5c\u51fa\u8a72\u9673\u8ff0\u7576\u65e5\u7684\u4e8b\u4ef6\u6216\u8cc7\u6599\u6709\u95dc\u3002\u9664\u6cd5\u5f8b\u898f\u5b9a\u5916\uff0c\u65bc\u4f5c\u51fa\u524d\u77bb\u6027\u9673\u8ff0\u7576\u65e5\u4e4b\u5f8c\uff0c\u7121\u8ad6\u662f\u5426\u51fa\u73fe\u65b0\u8cc7\u6599\u3001\u672a\u4f86\u4e8b\u4ef6\u6216\u5176\u4ed6\u60c5\u6cc1\uff0c\u6211\u5011\u4e26\u7121\u8cac\u4efb\u66f4\u65b0\u6216\u516c\u958b\u4fee\u6539\u4efb\u4f55\u524d\u77bb\u6027\u9673\u8ff0\u53ca\u9810\u6599\u4e4b\u5916\u7684\u4e8b\u4ef6\u3002\u8acb\u7d30\u95b1\u672c\u6587\uff0c\u4e26\u7406\u89e3\u6211\u5011\u7684\u5be6\u969b\u672a\u4f86\u696d\u7e3e\u6216\u8868\u73fe\u53ef\u80fd\u8207\u9810\u671f\u6709\u91cd\u5927\u5dee\u7570\u3002\u672c\u6587\u5167\u6240\u6709\u9673\u8ff0\u4e43\u672c\u6587\u7ae0\u520a\u767c\u65e5\u671f\u4f5c\u51fa\uff0c\u53ef\u80fd\u56e0\u672a\u4f86\u767c\u5c55\u800c\u51fa\u73fe\u8b8a\u52d5<span id=\"spanHghlt774d\">\u3002<\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u9019\u662f\u7e7c\u6b50\u76df\u59d4\u54e1\u6703\u6279\u51c6\u5f8c\uff0c\u8212\u683c\u5229&#8230;<\/p>\n","protected":false},"author":16,"featured_media":199219,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-272717","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u570b\u7522PD-L1\u9996\u5ea6\u5728\u82f1\u570b\u7372\u6279\uff01\u57fa\u77f3\u85e5\u696d\u5ba3\u5e03\u8212\u683c\u5229\u55ae\u6297\u7372\u82f1\u570b\u85e5\u54c1\u548c\u91ab\u7642\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\u6279\u51c6 \u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u975e\u5c0f\u7d30\u80de\u80ba\u764c - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831<\/title>\n<meta name=\"description\" content=\"\u9019\u662f\u7e7c\u6b50\u76df\u59d4\u54e1\u6703\u6279\u51c6\u5f8c\uff0c\u8212\u683c\u5229\u55ae\u6297\u5728\u4e2d\u570b\u5883\u5916\u7372\u5f97\u7684\u7b2c\u4e8c\u9805\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u7684\u6279\u51c6\u3002  \u6b64\u6b21\u6279\u51c6\u662f\u57fa\u65bc\u8212\u683c\u5229\u55ae\u6297III\u671f\u81e8\u5e8a\u7814\u7a76GEMSTONE-302\u7684\u7d50\u679c\uff0c\u8a72\u7814\u7a76\u5df2\u8b49\u660e\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u53ef\u986f\u8457\u5ef6\u9577\u521d\u6cbb\u8f49\u79fb\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\u548c\u7e3d\u751f\u5b58\u671f\u3002  GEMSTONE-302\u7814\u7a76\u7684\u9577\u671f\u6cbb\u7642\u548c\u751f\u5b58\u6578\u64da\u5df2\u57282024\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\uff08ESMO\uff09\u5e74\u6703\u4e0a\u516c\u5e03\u3002  \u8212\u683c\u5229\u55ae\u6297\u5176\u4ed6\u9069\u61c9\u75c7\u5728\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u7b49\u76e3\u7ba1\u6a5f\u69cb\u7684\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u6b63\u5728\u9032\u884c\u4e2d\u3002  \u57fa\u77f3\u85e5\u696d\u5df2\u8207Ewopharma\u9054\u6210\u8212\u683c\u5229\u55ae\u6297\u5728\u4e2d\u6b50\u3001\u6771\u6b50\u548c\u745e\u58eb\u7684\u5546\u696d\u5316\u6230\u7565\u5408\u4f5c\uff0c\u9810\u8a08\u8fd1\u671f\u5c07\u5728\u897f\u6b50\u3001\u62c9\u4e01\u7f8e\u6d32\u3001\u4e2d\u6771\u3001\u6771\u5357\u4e9e\u7b49\u5730\u5340\u9054\u6210\u66f4\u591a\u7684\u5546\u696d\u5408\u4f5c\u5354\u8b70\u3002  \u4e2d\u570b\u8607\u5dde2024\u5e7410\u670831\u65e5 \/\u7f8e\u901a\u793e\/ -- \u57fa\u77f3\u85e5\u696d\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc\uff1a2616\uff09\uff0c\u4e00\u5bb6\u5c08\u6ce8\u65bc\u6297\u816b\u7624\u85e5\u7269\u7814\u767c\u7684\u5275\u65b0\u9a45\u52d5\u578b\u751f\u7269\u91ab\u85e5\u4f01\u696d\uff0c\u4eca\u65e5\u5ba3\u5e03\uff0c\u82f1\u570b\u85e5\u54c1\u548c\u91ab\u7642\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\uff08MHRA\uff09\u5df2\u6279\u51c6\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u542b\u9251\u5316\u7642\u7528\u65bc\u7121EGFR\u654f\u611f\u7a81\u8b8a, \u6216\u7121ALK, ROS1, RET\u57fa\u56e0\u7d44\u816b\u7624\u8b8a\u7570\u7684\u8f49\u79fb\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u6210\u4eba\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002\u9019\u662f\u7e7c\u6b50\u76df\u59d4\u54e1\u6703\u6279\u51c6\u4e4b\u5f8c\uff0c\u8212\u683c\u5229\u55ae\u6297\u5728\u6d77\u5916\u5e02\u5834\u7372\u5f97\u7684\u7b2c\u4e8c\u9805\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u7684\u6279\u51c6\u3002 \u57fa\u77f3\u85e5\u696d\u9996\u5e2d\u57f7\u884c\u5b98\u3001\u7814\u767c\u7e3d\u88c1\u3001\u57f7\u884c\u8463\u4e8b\u694a\u5efa\u65b0\u535a\u58eb\u8868\u793a\uff1a\u300c\u8212\u683c\u5229\u55ae\u6297\u5728\u82f1\u570b\u7372\u6279\uff0c\u6a19\u5fd7\u8457\u6211\u5011\u5168\u7403\u5316\u5e03\u5c40\u7684\u53c8\u4e00\u91cd\u8981\u88e1\u7a0b\u7891\u3002\u8212\u683c\u5229\u55ae\u6297\u662f\u9996\u500b\u6210\u529f\u51fa\u6d77\u7684\u570b\u7522PD-L1\u55ae\u6297\uff0c\u5728\u767b\u9678\u5168\u7403\u7b2c\u4e8c\u5927\u91ab\u85e5\u5e02\u5834\u2014\u2014\u6b50\u76df\u4e4b\u5f8c\uff0c\u8212\u683c\u5229\u300e\u518d\u4e0b\u4e00\u57ce\u300f\uff0c\u62ff\u5230\u82f1\u570b\u9019\u4e00\u91cd\u8981\u6d77\u5916\u5e02\u5834\u7684\u300e\u5165\u5834\u5238\u300f\u3002\u5728\u4eca\u5e74ESMO\u4e0a\u516c\u5e03\u7684\u9577\u671f\u751f\u5b58\u6578\u64da\uff0c\u66f4\u662f\u9032\u4e00\u6b65\u978f\u56fa\u4e86\u8212\u683c\u5229\u55ae\u6297\u5728\u8f49\u79fb\u6027NSCLC\u4e00\u7dda\u6cbb\u7642\u683c\u5c40\u4e2d\u7684\u91cd\u8981\u5730\u4f4d\u3002\u300d \u694a\u535a\u58eb\u88dc\u5145\u9053\uff1a\u300c\u6d77\u5916\u5546\u696d\u5316\u548c\u6ce8\u518a\u65b9\u9762\uff0c\u6211\u5011\u6b63\u7a4d\u6975\u8207\u4f86\u81ea\u897f\u6b50\u3001\u62c9\u7f8e\u3001\u4e2d\u6771\u3001\u6771\u5357\u4e9e\u3001\u52a0\u62ff\u5927\u7b49\u5730\u5340\u7684\u5408\u4f5c\u4f19\u4f34\u6d3d\u8ac7\uff0c\u9810\u8a08\u8fd1\u671f\u5c07\u9054\u6210\u5176\u4e2d\u591a\u9805\u5546\u696d\u5408\u4f5c\u3002\u540c\u6642\uff0c\u6211\u5011\u5728\u7a4d\u6975\u8207\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u7b49\u570b\u969b\u76e3\u7ba1\u6a5f\u69cb\u6e9d\u901a\u8212\u683c\u5229\u55ae\u6297\u5176\u4ed6\u9069\u61c9\u75c7\uff0c\u5982III\u671fNSCLC\u3001\u4e00\u7dda\u80c3\u764c\u3001\u4e00\u7dda\u98df\u7ba1\u9c57\u764c\u7684\u4e0a\u5e02\u7533\u8acb\uff0c\u671f\u5f85\u70ba\u5168\u7403\u66f4\u591a\u60a3\u8005\u5e36\u4f86\u5275\u65b0\u7684\u6cbb\u7642\u65b9\u6848\u3002\u300d \u6b64\u6b21\u7372\u6279\u4e3b\u8981\u662f\u57fa\u65bc\u4e00\u9805\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u96d9\u76f2\u7684III\u671f\u81e8\u5e8a\u7814\u7a76\u2014\u2014GEMSTONE-302\u7684\u7d50\u679c\u3002\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u5316\u7642\u5c0d\u6bd4\u5b89\u6170\u5291\u806f\u5408\u5316\u7642\uff0c\u53ef\u986f\u8457\u5ef6\u9577\u521d\u6cbb\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u7121\u9032\u5c55\u751f\u5b58\u671f\u548c\u7e3d\u751f\u5b58\u671f\u3002\u8a72\u7814\u7a76\u6578\u64da\u5df2\u5728\u300a\u67f3\u8449\u5200\u00b7\u816b\u7624\u5b78\u300b\uff08Lancet Oncology\uff09\u548c\u300a\u81ea\u7136\u00b7\u764c\u75c7\u300b\uff08Nature Cancer\uff09\u4e0a\u767c\u8868\uff0c\u4e26\u66fe\u591a\u6b21\u5728\u570b\u969b\u5b78\u8853\u6703\u8b70\u4e0a\u4ee5\u53e3\u982d\u532f\u5831\u548c\u58c1\u5831\u5f62\u5f0f\u516c\u5e03\u3002 \u95dc\u65bc\u8212\u683c\u5229\u55ae\u6297\u6ce8\u5c04\u6db2 \u8212\u683c\u5229\u55ae\u6297\u662f\u7531\u57fa\u77f3\u85e5\u696d\u7814\u767c\u7684\u6297PD-L1\u55ae\u514b\u9686\u6297\u9ad4\uff0c\u8212\u683c\u5229\u55ae\u6297\u7684\u958b\u767c\u662f\u57fa\u65bc\u7f8e\u570bLigand\u516c\u53f8\u6388\u6b0a\u5f15\u9032\u7684OmniRat\u00ae\u8f49\u57fa\u56e0\u52d5\u7269\u5e73\u53f0\u3002\u8a72\u5e73\u53f0\u53ef\u4e00\u7ad9\u5f0f\u7522\u751f\u5168\u4eba\u6e90\u6297\u9ad4\u3002\u4f5c\u70ba\u4e00\u7a2e\u5168\u4eba\u6e90\u5168\u9577\u6297PD-L1\u55ae\u514b\u9686\u6297\u9ad4\uff0c\u8212\u683c\u5229\u55ae\u6297\u662f\u4e00\u7a2e\u6700\u63a5\u8fd1\u4eba\u9ad4\u7684\u5929\u7136G\u578b\u514d\u75ab\u7403\u86cb\u767d4\uff08IgG4\uff09\u55ae\u6297\u85e5\u7269\uff0c\u80fd\u964d\u4f4e\u5728\u60a3\u8005\u9ad4\u5167\u7522\u751f\u514d\u75ab\u539f\u6027\u53ca\u76f8\u95dc\u6bd2\u6027\u7684\u6f5b\u5728\u98a8\u96aa\uff0c\u8207\u540c\u985e\u85e5\u7269\u76f8\u6bd4\u8212\u683c\u5229\u55ae\u6297\u5c07\u5177\u6709\u7368\u7279\u512a\u52e2\u3002\u8212\u683c\u5229\u55ae\u6297\u7368\u7279\u5206\u5b50\u8a2d\u8a08\u4f7f\u5176\u5177\u5099\u96d9\u91cd\u4f5c\u7528\u6a5f\u5236\uff0c\u4e0d\u50c5\u963b\u65b7PD-1\/PD-L1\u76f8\u4e92\u4f5c\u7528\uff0c\u9084\u80fd\u901a\u904e\u4ecb\u5c0ePD-L1\u8868\u9054\u967d\u6027\u7684\u816b\u7624\u7d30\u80de\u8207\u816b\u7624\u76f8\u95dc\u5de8\u566c\u7d30\u80de\uff08TAMs\uff09\uff0c\u5728\u8a98\u5c0e\u6297\u9ad4\u4f9d\u8cf4\u6027\u7d30\u80de\u541e\u566c\uff08ADCP\uff09\u7684\u540c\u6642\u4e0d\u640d\u5bb3\u6548\u61c9\u6027T\u7d30\u80de\u3002\u9019\u7a2e\u5dee\u7570\u5316\u8a2d\u8a08\u4f7f\u8212\u683c\u5229\u55ae\u6297\u5728\u4e0d\u540c\u985e\u578b\u7684\u816b\u7624\u4e2d\u5c55\u73fe\u51fa\u4e86\u6f5b\u5728\u540c\u985e\u6700\u512a\u7684\u7642\u6548\u548c\u5b89\u5168\u6027\u3002 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\u806f\u5408\u542b\u6c1f\u5c3f\u5627\u5576\u985e\u548c\u9251\u985e\u85e5\u7269\u5316\u7642\u7528\u65bc\u8868\u9054PD-L1\uff08\u7d9c\u5408\u967d\u6027\u8a55\u5206\u22655\uff09\u7684\u4e0d\u53ef\u624b\u8853\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027\u80c3\u53ca\u80c3\u98df\u7ba1\u7d50\u5408\u90e8\u817a\u764c\u7684\u4e00\u7dda\u6cbb\u7642\u3002  \u6b50\u76df\u59d4\u54e1\u6703\uff08EC\uff09\u5df2\u6279\u51c6\u8212\u683c\u5229\u55ae\u6297\uff08\u5546\u54c1\u540d\uff1aCejemly\u00ae\uff09\u806f\u5408\u542b\u9251\u5316\u7642\u7528\u65bc\u7121EGFR\u654f\u611f\u7a81\u8b8a, \u6216\u7121ALK, ROS1, RET\u57fa\u56e0\u7d44\u816b\u7624\u8b8a\u7570\u7684\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002 \u82f1\u570b\u85e5\u54c1\u548c\u91ab\u7642\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\uff08MHRA\uff09\u5df2\u6279\u51c6\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u542b\u9251\u5316\u7642\u7528\u65bc\u7121EGFR\u654f\u611f\u7a81\u8b8a, \u6216\u7121ALK, ROS1, RET\u57fa\u56e0\u7d44\u816b\u7624\u8b8a\u7570\u7684\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002 \u95dc\u65bc\u57fa\u77f3\u85e5\u696d \u57fa\u77f3\u85e5\u696d\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc: 2616\uff09\u6210\u7acb\u65bc2015\u5e74\u5e95\uff0c\u662f\u4e00\u5bb6\u5c08\u6ce8\u65bc\u6297\u816b\u7624\u85e5\u7269\u7814\u767c\u7684\u5275\u65b0\u9a45\u52d5\u578b\u751f\u7269\u91ab\u85e5\u4f01\u696d\uff0c\u81f4\u529b\u65bc\u6eff\u8db3\u4e2d\u570b\u548c\u5168\u7403\u764c\u75c7\u60a3\u8005\u7684\u6bb7\u5207\u91ab\u7642\u9700\u6c42\u3002\u622a\u81f3\u76ee\u524d\uff0c\u516c\u53f8\u5df2\u6210\u529f\u4e0a\u5e024\u6b3e\u5275\u65b0\u85e5\u3001\u7372\u627916\u9805\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\u4ee5\u53ca9\u9805\u9069\u61c9\u75c7\u3002\u7576\u524d\u7814\u767c\u7ba1\u7dda\u5747\u8861\u914d\u7f6e\u4e86\u6f5b\u5728\u540c\u985e\u9996\u5275\u6216\u540c\u985e\u6700\u4f73\u7684\u6297\u9ad4\u5076\u806f\u85e5\u7269\uff08ADC\uff09\u3001\u591a\u7279\u7570\u6027\u6297\u9ad4\u3001\u4ee5\u53ca\u514d\u75ab\u7642\u6cd5\u548c\u7cbe\u51c6\u6cbb\u7642\u85e5\u7269\u5728\u5167\u768416\u6b3e\u5019\u9078\u85e5\u7269\u3002\u540c\u6642\uff0c\u57fa\u77f3\u85e5\u696d\u64c1\u6709\u4e00\u652f\u8cc7\u6df1\u7ba1\u7406\u5718\u968a\uff0c\u300c\u5168\u93c8\u689d\u300d\u8986\u84cb\u81e8\u5e8a\u524d\u63a2\u7d22\u3001\u81e8\u5e8a\u8f49\u5316\u3001\u81e8\u5e8a\u958b\u767c\u3001\u85e5\u7269\u751f\u7522\u3001\u5546\u52d9\u62d3\u5c55\u3001\u5546\u696d\u904b\u71df\u7b49\u95dc\u9375\u74b0\u7bc0\u3002 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name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=272717\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u570b\u7522PD-L1\u9996\u5ea6\u5728\u82f1\u570b\u7372\u6279\uff01\u57fa\u77f3\u85e5\u696d\u5ba3\u5e03\u8212\u683c\u5229\u55ae\u6297\u7372\u82f1\u570b\u85e5\u54c1\u548c\u91ab\u7642\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\u6279\u51c6 \u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u975e\u5c0f\u7d30\u80de\u80ba\u764c - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u9019\u662f\u7e7c\u6b50\u76df\u59d4\u54e1\u6703\u6279\u51c6\u5f8c\uff0c\u8212\u683c\u5229\u55ae\u6297\u5728\u4e2d\u570b\u5883\u5916\u7372\u5f97\u7684\u7b2c\u4e8c\u9805\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u7684\u6279\u51c6\u3002  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\u57fa\u77f3\u85e5\u696d\u5df2\u8207Ewopharma\u9054\u6210\u8212\u683c\u5229\u55ae\u6297\u5728\u4e2d\u6b50\u3001\u6771\u6b50\u548c\u745e\u58eb\u7684\u5546\u696d\u5316\u6230\u7565\u5408\u4f5c\uff0c\u9810\u8a08\u8fd1\u671f\u5c07\u5728\u897f\u6b50\u3001\u62c9\u4e01\u7f8e\u6d32\u3001\u4e2d\u6771\u3001\u6771\u5357\u4e9e\u7b49\u5730\u5340\u9054\u6210\u66f4\u591a\u7684\u5546\u696d\u5408\u4f5c\u5354\u8b70\u3002  \u4e2d\u570b\u8607\u5dde2024\u5e7410\u670831\u65e5 \/\u7f8e\u901a\u793e\/ -- \u57fa\u77f3\u85e5\u696d\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc\uff1a2616\uff09\uff0c\u4e00\u5bb6\u5c08\u6ce8\u65bc\u6297\u816b\u7624\u85e5\u7269\u7814\u767c\u7684\u5275\u65b0\u9a45\u52d5\u578b\u751f\u7269\u91ab\u85e5\u4f01\u696d\uff0c\u4eca\u65e5\u5ba3\u5e03\uff0c\u82f1\u570b\u85e5\u54c1\u548c\u91ab\u7642\u4fdd\u5065\u7528\u54c1\u7ba1\u7406\u5c40\uff08MHRA\uff09\u5df2\u6279\u51c6\u8212\u683c\u5229\u55ae\u6297\u806f\u5408\u542b\u9251\u5316\u7642\u7528\u65bc\u7121EGFR\u654f\u611f\u7a81\u8b8a, 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2616\uff09\u6210\u7acb\u65bc2015\u5e74\u5e95\uff0c\u662f\u4e00\u5bb6\u5c08\u6ce8\u65bc\u6297\u816b\u7624\u85e5\u7269\u7814\u767c\u7684\u5275\u65b0\u9a45\u52d5\u578b\u751f\u7269\u91ab\u85e5\u4f01\u696d\uff0c\u81f4\u529b\u65bc\u6eff\u8db3\u4e2d\u570b\u548c\u5168\u7403\u764c\u75c7\u60a3\u8005\u7684\u6bb7\u5207\u91ab\u7642\u9700\u6c42\u3002\u622a\u81f3\u76ee\u524d\uff0c\u516c\u53f8\u5df2\u6210\u529f\u4e0a\u5e024\u6b3e\u5275\u65b0\u85e5\u3001\u7372\u627916\u9805\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\u4ee5\u53ca9\u9805\u9069\u61c9\u75c7\u3002\u7576\u524d\u7814\u767c\u7ba1\u7dda\u5747\u8861\u914d\u7f6e\u4e86\u6f5b\u5728\u540c\u985e\u9996\u5275\u6216\u540c\u985e\u6700\u4f73\u7684\u6297\u9ad4\u5076\u806f\u85e5\u7269\uff08ADC\uff09\u3001\u591a\u7279\u7570\u6027\u6297\u9ad4\u3001\u4ee5\u53ca\u514d\u75ab\u7642\u6cd5\u548c\u7cbe\u51c6\u6cbb\u7642\u85e5\u7269\u5728\u5167\u768416\u6b3e\u5019\u9078\u85e5\u7269\u3002\u540c\u6642\uff0c\u57fa\u77f3\u85e5\u696d\u64c1\u6709\u4e00\u652f\u8cc7\u6df1\u7ba1\u7406\u5718\u968a\uff0c\u300c\u5168\u93c8\u689d\u300d\u8986\u84cb\u81e8\u5e8a\u524d\u63a2\u7d22\u3001\u81e8\u5e8a\u8f49\u5316\u3001\u81e8\u5e8a\u958b\u767c\u3001\u85e5\u7269\u751f\u7522\u3001\u5546\u52d9\u62d3\u5c55\u3001\u5546\u696d\u904b\u71df\u7b49\u95dc\u9375\u74b0\u7bc0\u3002 \u5982\u9700\u4e86\u89e3\u6709\u95dc\u57fa\u77f3\u85e5\u696d\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\uff1awww.cstonepharma.com\u3002\u6295\u8cc7\u8005\u95dc\u7cfb: ir@cstonepharma.com\u5a92\u9ad4\u95dc\u7cfb: pr@cstonepharma.com \u524d\u77bb\u6027\u8072\u660e 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RET\u57fa\u56e0\u7d44\u816b\u7624\u8b8a\u7570\u7684\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002 \u95dc\u65bc\u57fa\u77f3\u85e5\u696d \u57fa\u77f3\u85e5\u696d\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc: 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RET\u57fa\u56e0\u7d44\u816b\u7624\u8b8a\u7570\u7684\u8f49\u79fb\u6027NSCLC\u60a3\u8005\u7684\u4e00\u7dda\u6cbb\u7642\u3002 \u95dc\u65bc\u57fa\u77f3\u85e5\u696d \u57fa\u77f3\u85e5\u696d\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc: 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