{"id":260431,"date":"2024-09-09T16:29:00","date_gmt":"2024-09-09T08:29:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=260431"},"modified":"2024-09-09T16:29:00","modified_gmt":"2024-09-09T08:29:00","slug":"esmo-2024-trop2-adc%e8%98%86%e5%ba%b7%e6%b2%99%e5%a6%a5%e7%8f%a0%e5%96%ae%e6%8a%97%e4%b8%89%e9%a0%85%e7%a0%94%e7%a9%b6%e7%b5%90%e6%9e%9c%e4%ba%ae%e7%9b%b82024%e5%b9%b4%e6%ad%90%e6%b4%b2%e8%85%ab","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=260431","title":{"rendered":"ESMO 2024 | TROP2 ADC\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297\u4e09\u9805\u7814\u7a76\u7d50\u679c\u4eae\u76f82024\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\u5e74\u6703"},"content":{"rendered":"
\n

\u6210\u90fd<\/span>2024\u5e749\u67089\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — 2024\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\uff08ESMO\uff09\u5e74\u6703\u5c07\u65bc9\u670813\u65e5\u81f317\u65e5\u5728\u897f\u73ed\u7259\u5df4\u585e\u7f85\u7d0d\u8209\u884c\u3002\u56db\u5ddd\u79d1\u502b\u535a\u6cf0\u751f\u7269\u91ab\u85e5\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7c21\u7a31”\u79d1\u502b\u535a\u6cf0”\uff0c<\/b>6990.HK<\/b>\uff09\u5c07\u5728<\/b>2024ESMO\u5e74\u6703\u4e0a\u516c\u4f48\u4e09\u9805\u81e8\u5e8a\u7814\u7a76\u7d50\u679c\u3002<\/b><\/p>\n

\n

<\/span><\/p>\n<\/p><\/div>\n

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2\u3001<\/b>\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297<\/b>(sac-TMT\uff09\u55ae\u85e5\u7642\u6cd5\u7528\u65bc\u65e2\u5f80\u63a5\u53d7\u904e\u6cbb\u7642\u7684\u665a\u671f\u5b50\u5bae\u5167\u819c\u764c(EC)\u53ca\u5375\u5de2\u764c(OC)\u60a3\u8005\u76842\u671f\u7814\u7a76\u7684\u5b89\u5168\u6027\u53ca\u7642\u6548<\/b>\u3002<\/p>\n

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CC<\/b><\/p>\n

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EC\u53caOC<\/b><\/p>\n

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\u5206\u5225\u670972.7%\u53ca67.5%\u7684EC\u548cOC\u60a3\u8005\u767c\u751f\u22653\u7d1aTRAE\u3002\u6700\u5e38\u898b\u7684\u22653\u7d1a TRAE\uff08\u226515%)\uff08EC\u53caOC\uff09\u70ba\u4e2d\u6027\u7c92\u7d30\u80de\u8a08\u6578\u6e1b\u5c11\uff0843.2%\u53ca30.0%\uff09\u3001\u767d\u7d30\u80de\u8a08\u6578\u6e1b\u5c11\uff0840.9%\u53ca22.5%\uff09\u3001\u8ca7\u8840\uff0829.5%\u53ca35.0%\uff09\u53ca\u53e3\u8154\u708e\uff0829.5%\u53ca35.0%\uff09\u3002\u5206\u5225\u67091\u4f8b (2.3%\uff09\u548c5\u4f8b\uff0812.5%\uff09\u7684EC\u548cOC\u60a3\u8005\u51fa\u73fe\u5c0e\u81f4\u505c\u85e5\u7684TRAE\u3002<\/p>\n

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TNBC<\/b><\/p>\n

\u65e2\u5f80\u63a5\u53d7\u904e\u22652\u7a2e\u6cbb\u7642\uff08\u5176\u4e2d\u81f3\u5c111\u7a2e\u6cbb\u7642\u91dd\u5c0d\u8f49\u79fb\u6027\u968e\u6bb5\uff09\u7684\u5c40\u90e8\u5fa9\u767c\u6216\u8f49\u79fb\u6027TNBC\u60a3\u8005\u96a8\u6a5f\u63a5\u53d7\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u6216\u7814\u7a76\u8005\u9078\u64c7\u65b9\u6848\uff08TPC\uff1a\u827e\u65e5\u5e03\u6797\u3001\u5361\u57f9\u4ed6\u6ff1\u3001\u5409\u897f\u4ed6\u6ff1\u6216\u9577\u6625\u745e\u6ff1\uff09\u3002\u4e3b\u8981\u7d42\u9ede\u70ba\u76f2\u614b\u7368\u7acb\u4e2d\u5fc3\u5be9\u95b1\u59d4\u54e1\u6703(BICR)\u8a55\u4f30\u7684PFS\u3002<\/p>\n

\u622a\u81f32023\u5e7411\u670830\u65e5\uff0c\u63a5\u53d7\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u6cbb\u7642\u7684\u60a3\u8005\u4e2d\u670924.6%\uff0832\/130\uff09\u65e2\u5f80\u63a5\u53d7\u904ePD-(L)1\u6291\u5236\u5291\u6cbb\u7642\uff0c\u63a5\u53d7TPC\u6cbb\u7642\u7684\u60a3\u8005\u4e2d\u670927.1%\uff0836\/133\uff09\u65e2\u5f80\u63a5\u53d7\u904ePD-(L)1\u6291\u5236\u5291\u6cbb\u7642\u3002\u5728\u8a72\u4e9e\u7d44\u4e2d\u89c0\u5bdf\u5230\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u5c0d\u6bd4TPC\u5177\u6709\u81e8\u5e8a\u7372\u76ca\u3002BICR\u8a55\u4f30\u7684\u4e2d\u4f4dPFS\u70ba5.6\u500b\u6708\u5c0d\u6bd42.7\u500b\u6708\uff08HR 0.31\uff1b95% CI 0.17-0.54\uff09\uff0cBICR\u8a55\u4f30\u7684\u63a5\u53d7\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u6cbb\u7642\u60a3\u8005\u7684ORR\u70ba56.3%\uff0c\u800c\u63a5\u53d7TPC\u6cbb\u7642\u60a3\u8005\u7684ORR\u70ba5.6%\u3002\u5c0d\u65bc\u65e2\u5f80\u672a\u63a5\u53d7\u904ePD-(L)1\u6291\u5236\u5291\u6cbb\u7642\u7684\u60a3\u8005\uff0c\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u5c0d\u6bd4TPC\u5728\u7642\u6548\u65b9\u9762\u6709\u985e\u4f3c\u7684\u6539\u5584\u3002\u4e2d\u4f4dPFS\u70ba7.2\u500b\u6708\u5c0d\u6bd42.3\u500b\u6708\uff08HR 0.34\uff1b95% CI 0.23-0.48\uff09\uff0cORR\u70ba41.8%\u5c0d\u6bd414.4%\u3002<\/p>\n

\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u7d44\u4e2d\u65e2\u5f80\u63a5\u53d7\u904e\u6216\u672a\u63a5\u53d7\u904ePD-(L)1\u6291\u5236\u5291\u6cbb\u7642\u7684\u60a3\u8005\u4e4b\u9593\u7684\u5b89\u5168\u6027\u8cc7\u6599\u76f8\u4f3c\u3002<\/p>\n

\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u7528\u65bc\u65e2\u5f80\u63a5\u53d7\u904e\u6cbb\u7642\u7684\u5c40\u90e8\u5fa9\u767c\u6216\u8f49\u79fb\u6027TNBC\u60a3\u8005\u76843\u671f\u7814\u7a76(OptiTROP-Breast01)\u7d50\u679c\u5df2\u65bc2024\u5e746\u67082\u65e5\u57282024\u5e74ASCO\u5e74\u6703\u4e0a\u9032\u884c\u4e86\u516c\u4f48\uff0c\u8a73\u60c5\u8f09\u65bc\u672c\u516c\u53f82024\u5e74\u4e2d\u671f\u696d\u7e3e\u516c\u544a\u53ca\u65e5\u671f\u70ba2024\u5e745\u670824\u65e5\u7684\u516c\u544a\u3002<\/p>\n

\u4e00\u9805\u7531\u9ed8\u6c99\u6771\u767c\u8d77\u7684\u8a55\u4f30\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u806f\u5408\u5e15\u535a\u5229\u73e0\u55ae\u6297\u5c0d\u6bd4TPC\u7528\u65bc\u65e2\u5f80\u63a5\u53d7\u904e\u65b0\u8f14\u52a9\u6cbb\u7642\u4e14\u672a\u9054\u5230\u75c5\u7406\u5b78\u5b8c\u5168\u7de9\u89e3(pCR)\u7684TNBC\u60a3\u8005\u76843\u671f\u5168\u7403\u7814\u7a76(NCT06393374)\uff0c\u53ca\u672c\u516c\u53f8\u767c\u8d77\u7684\u4e00\u9805\u8a55\u4f30\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u5728\u4e2d\u570b\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u4e0d\u53ef\u624b\u8853\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u5fa9\u767c\u6216\u8f49\u79fb\u6027PD-L1\u9670\u6027TNBC\u60a3\u8005\u76843\u671f\u7814\u7a76(NCT06279364)\u5747\u6b63\u5728\u9032\u884c\u4e2d\u3002<\/p>\n

\u65bc2022\u5e745\u6708\uff0c\u672c\u516c\u53f8\u6388\u4e88\u9ed8\u6c99\u6771\uff08\u7f8e\u570b\u65b0\u6fa4\u897f\u5dde\u7f85\u5a01\u5e02\u9ed8\u514b\u516c\u53f8\u7684\u5546\u865f\uff09\u5728\u5927\u4e2d\u83ef\u5340\uff08\u5305\u62ec\u4e2d\u570b\u5167\u5730\u3001\u9999\u6e2f\u3001\u6fb3\u9580\u4ee5\u53ca\u81fa\u7063\uff09\u4ee5\u5916\u7684\u6240\u6709\u5730\u5340\u958b\u767c\u3001\u4f7f\u7528\u3001\u88fd\u9020\u53ca\u5546\u696d\u5316\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT) \u7684\u7368\u5bb6\u6b0a\u5229\u3002\u53ef\u745e\u9054\u00ae\u70ba\u7f8e\u570b\u65b0\u6fa4\u897f\u5dde\u7f85\u5a01\u5e02\u9ed8\u514b\u516c\u53f8\u7684\u9644\u5c6c\u516c\u53f8Merck Sharp & Dohme LLC\u7684\u6ce8\u518a\u5546\u6a19\u3002<\/p>\n

\u5bae\u9838\u764c\u767c\u75c5\u7387\u5c45\u5a66\u79d1\u4e09\u5927\u60e1\u6027\u816b\u7624\u4e4b\u9996\uff0c\u662f\u5c0e\u81f4\u5973\u6027\u764c\u75c7\u6b7b\u4ea1\u7684\u7b2c\u56db\u5927\u539f\u56e0\u3002\u64da\u300a\u4e2d\u570b\u60e1\u6027\u816b\u7624\u5b78\u79d1\u767c\u5c55\u5831\u544a\uff082023\uff09\u300b\u986f\u793a\uff0c\u4e2d\u570b\u5a66\u79d1\u816b\u7624\u7684\u767c\u75c5\u7387\u7e7c\u7e8c\u5448\u73fe\u4e0a\u5347\u7684\u8da8\u52e2\uff0c\u5176\u4e2d\u5bae\u9838\u764c\u5e74\u767c\u75c5\u4f8b\u6578\u70ba119300\u4f8b\uff0c\u5e74\u6b7b\u4ea1\u75c5\u4f8b\u6578\u70ba37200\u4f8b[1]<\/sup>\u3002\u5b50\u5bae\u5167\u819c\u764c(EC)\u4f5c\u70ba\u7e7c\u5bae\u9838\u764c(CC)\u4e4b\u5f8c\u7b2c\u4e8c\u7a2e\u5e38\u898b\u7684\u5a66\u79d1\u60e1\u6027\u816b\u7624\uff0c\u5360\u5a66\u79d1\u60e1\u6027\u816b\u7624\u768420%\uff5e30%\uff0c2022\u5e74\u6211\u570b\u65b0\u767c\u75c5\u4f8b7.77\u842c\u4f8b\uff0c\u6b7b\u4ea1\u75c5\u4f8b1.35\u842c\u4f8b[2]<\/sup>\uff1b\u624b\u8853\u662f\u5b50\u5bae\u5167\u819c\u764c\u7684\u4e3b\u8981\u6cbb\u7642\u624b\u6bb5\uff0c\u9664\u4e0d\u80fd\u8010\u53d7\u624b\u8853\u6216\u665a\u671f\u7121\u6cd5\u624b\u8853\u7684\u60a3\u8005\u5916\uff0c\u90fd\u61c9\u9032\u884c\u624b\u8853\u6cbb\u7642\u4e26\u8f14\u4ee5\u653e\u5c04\u6cbb\u7642\u3001\u5316\u5b78\u6cbb\u7642\u3001\u6fc0\u7d20\u548c\u514d\u75ab\u9776\u5411\u6cbb\u7642\u7b49\u7d9c\u5408\u6cbb\u7642\u3002\u6b64\u5916\uff0c\u5375\u5de2\u764c\u4f5c\u70ba\u7b2c\u4e09\u7a2e\u5e38\u898b\u7684\u5a66\u79d1\u60e1\u6027\u816b\u7624\uff0c\u5176\u767c\u75c5\u7387\u4e5f\u5c45\u9ad8\u4e0d\u4e0b\u30022022\u5e74\u6211\u570b\u5375\u5de2\u764c(OC)\u65b0\u767c\u60a3\u8005\u6578\u70ba6.11\u842c\u4eba[2]<\/sup>,\u767c\u75c5\u7387\u4f4d\u5c45\u5973\u6027\u751f\u6b96\u7cfb\u7d71\u816b\u7624\u7684\u7b2c3\u4f4d\u5143[3]<\/sup>\u3002<\/p>\n

\u9664\u4e86\u4ee5\u4e0a\u4e09\u7a2e\u5e38\u898b\u7684\u5a66\u79d1\u60e1\u6027\u816b\u7624\uff0c\u4e73\u817a\u764c\u4e5f\u540c\u6a23\u5a01\u8105\u8457\u5973\u6027\u7684\u751f\u547d\u5065\u5eb7\u3002\u5176\u4e2d\uff0c\u4e09\u9670\u6027\u4e73\u817a\u764c\u5177\u6709\u7368\u7279\u7684\u751f\u7269\u884c\u70ba\u5b78\u7279\u5fb5\uff0c\u53c8\u88ab\u7a31\u70ba”\u6700\u6bd2”\u4e73\u817a\u764c\u30022022\u5e74\u4e2d\u570b\u60e1\u6027\u816b\u7624\u6d41\u884c\u8cc7\u6599\u5206\u6790\u986f\u793a\uff0c\u4e2d\u570b\u5973\u6027\u4e73\u817a\u764c\u5e74\u65b0\u767c\u75c5\u4f8b35.7\u842c\uff0c\u6b7b\u4ea1\u75c5\u4f8b7.5\u842c[4]<\/sup>\u3002\u4e09\u9670\u6027\u4e73\u817a\u764c\u7f3a\u4e4f\u6709\u6548\u7684\u6cbb\u7642\u9776\u9ede\uff0c\u5316\u7642\u662f\u81e8\u5e8a\u4e2d\u6700\u4e3b\u8981\u7684\u7cfb\u7d71\u6cbb\u7642\u624b\u6bb5[5]<\/sup>\uff0c\u4f46\u5f80\u5f80\u7642\u6548\u6b20\u4f73\uff0c\u4e14\u6bd2\u526f\u4f5c\u7528\u8f03\u5927\uff0c\u9810\u5f8c\u8207\u5176\u4ed6\u4e9e\u578b\u4e73\u817a\u764c\u76f8\u6bd4\u53ef\u8b02\u5929\u5dee\u5730\u5225[6]<\/sup>\uff0c\u4e9f\u9700\u901a\u904e\u63a2\u7d22\u66f4\u591a\u7684\u6cbb\u7642\u624b\u6bb5\u63d0\u5347\u81e8\u5e8a\u7372\u76ca\u3002<\/p>\n

\u6b64\u6b21\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT)\u5728ESMO\u5927\u6703\u516c\u4f48\u7684\u91dd\u5c0d\u4e0d\u540c\u9069\u61c9\u75c7\u7684\u7814\u7a76\u6210\u679c\uff0c\u6709\u671b\u9032\u4e00\u6b65\u6eff\u8db3\u5305\u62ec\u4e09\u9670\u6027\u4e73\u817a\u764c\u5728\u5167\u7684\u5a66\u79d1\u816b\u7624\u7684\u6cbb\u7642\u9700\u6c42\uff0c\u4f7f\u66f4\u591a\u7684\u81e8\u5e8a\u60a3\u8005\u7372\u76ca\u3002<\/p>\n

\n

\"\"<\/a>
<\/span><\/p>\n<\/p><\/div>\n

\u79d1\u502b\u535a\u6cf0\u9996\u5e2d\u57f7\u884c\u5b98\u845b\u5747\u53cb\u535a\u58eb\u8868\u793a\uff1a\u300c<\/span>\u5805\u6301\u6e90\u982d\u5275\u65b0\uff0c\u81ea\u8eab\u64c1\u6709\u570b\u969b\u4e00\u6d41\u7684\u5275\u65b0\u80fd\u529b\uff0c\u662f\u5275\u65b0\u85e5\u4f01\u696d\u53ef\u6301\u7e8c\u767c\u5c55\u7684\u5148\u6c7a\u689d\u4ef6\u3002\u975e\u5e38\u9ad8\u8208TROP2 ADC\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297\u5728ESMO\u5927\u6703\u516c\u4f48\u7684\u591a\u500b\u5a66\u79d1\u816b\u7624\u9069\u61c9\u75c7\u7814\u7a76\u4e2d\uff0c\u5728\u591a\u9805\u8cc7\u6599\u6210\u679c\u4e0a\u5c55\u73fe\u51fa\u512a\u7570\u7684\u81e8\u5e8a\u7642\u6548\u548c\u5b89\u5168\u6027\u3002\u79d1\u502b\u535a\u6cf0\u59cb\u7d42\u81f4\u529b\u65bc\u89e3\u6c7a\u4e2d\u570b\u4e43\u81f3\u5168\u7403\u672a\u6eff\u8db3\u7684\u91ab\u7642\u9700\u6c42\uff0c\u80f8\u61f7\u5168\u7403\u60a3\u8005\uff0c\u4ee5\u60a3\u8005\u7372\u76ca\u70ba\u9996\u8981\u76ee\u6a19\u3002\u59cb\u7d42\u61f7\u63e3\u60a3\u8005\u7b2c\u4e00\u7684\u535a\u611b\u4e4b\u5fc3\uff0c\u6211\u5011\u671f\u5f85\u80fd\u70ba\u5168\u7403\u60a3\u8005\u63d0\u4f9b\u81e8\u5e8a\u50f9\u503c\u986f\u8457\u4e14\u6027\u50f9\u6bd4\u512a\u7570\u7684\u4e2d\u570bADC\u5275\u65b0\u85e5\u3002\u300d<\/span><\/p>\n

\u53c3\u8003\u6587\u737b\uff1a<\/p>\n

\n\n\n\n\n\n\n\n
\n

[1]\u300a\u4e2d\u570b\u60e1\u6027\u816b\u7624\u5b78\u79d1\u767c\u5c55\u5831\u544a\uff082023\uff09\u300b.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[2]\u00a0Han\u00a0B,\u00a0Zheng\u00a0R,\u00a0Zeng\u00a0H,\u00a0Wang\u00a0S,\u00a0Sun\u00a0K,\u00a0Chen\u00a0R,\u00a0Li\u00a0L,\u00a0Wei\u00a0W,\u00a0He\u00a0J.\u00a0Cancer\u00a0incidence\u00a0and\u00a0mortality\u00a0in\u00a0China,\u00a02022.\u00a0J\u00a0Natl\u00a0Cancer\u00a0Center.\u00a02024;4(1).<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[3] Ovarian Cancer datamonitor.
[4].Han,\u00a0Bingfeng,\u00a0et\u00a0al.\u00a0“Cancer\u00a0incidence\u00a0and\u00a0mortality\u00a0in\u00a0China,\u00a02022.”\u00a0Journal\u00a0of\u00a0the\u00a0National\u00a0Cancer\u00a0Center\u00a04.1\u00a0(2024):\u00a047-53.\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[5]. [\u4e2d\u570b\u81e8\u5e8a\u816b\u7624\u5b78\u6703(CSCO)(2024)]\u4e73\u817a\u764c\u8a3a\u7642\u6307\u5357.<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

[6]. https:\/\/seer.cancer.gov\/statfacts\/html\/breast-subtypes.html<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n

\u00a0<\/p>\n

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ADC\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297\u5728ESMO\u5927\u6703\u516c\u4f48\u7684\u591a\u500b\u5a66\u79d1\u816b\u7624\u9069\u61c9\u75c7\u7814\u7a76\u4e2d\uff0c\u5728\u591a\u9805\u8cc7\u6599\u6210\u679c\u4e0a\u5c55\u73fe\u51fa\u512a\u7570\u7684\u81e8\u5e8a\u7642\u6548\u548c\u5b89\u5168\u6027\u3002\u79d1\u502b\u535a\u6cf0\u59cb\u7d42\u81f4\u529b\u65bc\u89e3\u6c7a\u4e2d\u570b\u4e43\u81f3\u5168\u7403\u672a\u6eff\u8db3\u7684\u91ab\u7642\u9700\u6c42\uff0c\u80f8\u61f7\u5168\u7403\u60a3\u8005\uff0c\u4ee5\u60a3\u8005\u7372\u76ca\u70ba\u9996\u8981\u76ee\u6a19\u3002\u59cb\u7d42\u61f7\u63e3\u60a3\u8005\u7b2c\u4e00\u7684\u535a\u611b\u4e4b\u5fc3\uff0c\u6211\u5011\u671f\u5f85\u80fd\u70ba\u5168\u7403\u60a3\u8005\u63d0\u4f9b\u81e8\u5e8a\u50f9\u503c\u986f\u8457\u4e14\u6027\u50f9\u6bd4\u512a\u7570\u7684\u4e2d\u570bADC\u5275\u65b0\u85e5\u3002\u300d \u53c3\u8003\u6587\u737b\uff1a \u300a\u4e2d\u570b\u60e1\u6027\u816b\u7624\u5b78\u79d1\u767c\u5c55\u5831\u544a\uff082023\uff09\u300b. \u00a0Han\u00a0B,\u00a0Zheng\u00a0R,\u00a0Zeng\u00a0H,\u00a0Wang\u00a0S,\u00a0Sun\u00a0K,\u00a0Chen\u00a0R,\u00a0Li\u00a0L,\u00a0Wei\u00a0W,\u00a0He\u00a0J.\u00a0Cancer\u00a0incidence\u00a0and\u00a0mortality\u00a0in\u00a0China,\u00a02022.\u00a0J\u00a0Natl\u00a0Cancer\u00a0Center.\u00a02024;4(1). Ovarian Cancer datamonitor..Han,\u00a0Bingfeng,\u00a0et\u00a0al.\u00a0"Cancer\u00a0incidence\u00a0and\u00a0mortality\u00a0in\u00a0China,\u00a02022."\u00a0Journal\u00a0of\u00a0the\u00a0National\u00a0Cancer\u00a0Center\u00a04.1\u00a0(2024):\u00a047-53.\u00a0 . \u4e73\u817a\u764c\u8a3a\u7642\u6307\u5357. . https:\/\/seer.cancer.gov\/statfacts\/html\/breast-subtypes.html \u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=260431\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ESMO 2024 | TROP2 ADC\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297\u4e09\u9805\u7814\u7a76\u7d50\u679c\u4eae\u76f82024\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\u5e74\u6703 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u6210\u90fd2024\u5e749\u67089\u65e5 \/\u7f8e\u901a\u793e\/ -- 2024\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\uff08ESMO\uff09\u5e74\u6703\u5c07\u65bc9\u670813\u65e5\u81f317\u65e5\u5728\u897f\u73ed\u7259\u5df4\u585e\u7f85\u7d0d\u8209\u884c\u3002\u56db\u5ddd\u79d1\u502b\u535a\u6cf0\u751f\u7269\u91ab\u85e5\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7c21\u7a31"\u79d1\u502b\u535a\u6cf0"\uff0c6990.HK\uff09\u5c07\u57282024ESMO\u5e74\u6703\u4e0a\u516c\u4f48\u4e09\u9805\u81e8\u5e8a\u7814\u7a76\u7d50\u679c\u3002 1\u3001\u8606\u5eb7\u6c99\u59a5\u73e0\u55ae\u6297(sac-TMT\uff0c\u524d\u7a31SKB264\/MK-2870)\u806f\u5408\u5e15\u535a\u5229\u73e0\u55ae\u6297\uff08\u53ef\u745e\u9054\u00ae\uff09\u7528\u65bc\u5fa9\u767c\u6216\u8f49\u79fb\u6027\u5bae\u9838\u764c(CC)\u60a3\u8005\u7684\u7642\u6548\u53ca\u5b89\u5168\u6027\u3002 \u6642\u9593\uff1a\u7576\u5730\u6642\u95932024\u5e749\u670815\u65e514:55\u81f315:00 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\u00a0Han\u00a0B,\u00a0Zheng\u00a0R,\u00a0Zeng\u00a0H,\u00a0Wang\u00a0S,\u00a0Sun\u00a0K,\u00a0Chen\u00a0R,\u00a0Li\u00a0L,\u00a0Wei\u00a0W,\u00a0He\u00a0J.\u00a0Cancer\u00a0incidence\u00a0and\u00a0mortality\u00a0in\u00a0China,\u00a02022.\u00a0J\u00a0Natl\u00a0Cancer\u00a0Center.\u00a02024;4(1). 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