{"id":249336,"date":"2024-07-18T14:42:00","date_gmt":"2024-07-18T06:42:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=249336"},"modified":"2024-07-18T14:42:00","modified_gmt":"2024-07-18T06:42:00","slug":"%e8%bc%9d%e7%91%9e%e5%ae%a3%e4%bd%88%e6%9c%ac%e6%9c%88%e8%b5%b7%e4%be%9b%e6%87%89%e9%a6%96%e6%ac%be%e6%93%81%e6%9c%89%e9%9b%99%e9%81%a9%e6%87%89%e7%97%87%e7%9a%84%e5%91%bc%e5%90%b8%e9%81%93%e5%90%88","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=249336","title":{"rendered":"\u8f1d\u745e\u5ba3\u4f48\u672c\u6708\u8d77\u4f9b\u61c9\u9996\u6b3e\u64c1\u6709\u96d9\u9069\u61c9\u75c7\u7684\u547c\u5438\u9053\u5408\u80de\u75c5\u6bd2\u75ab\u82d7\u4e88\u9999\u6e2f"},"content":{"rendered":"<div>\n<table name=\"logo_release\" border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul type=\"disc\">\n<li><i>\u9996\u500b<\/i><i>\u53ca<\/i><i>\u552f\u4e00\u4e00\u6b3e\u6709\u6548\u540c\u6642\u91dd\u5c0d<\/i><i>RSV A<\/i><i>\u53ca<\/i><i>RSV B<\/i><i>\u75c5\u6bd2<\/i><i>\u7684\u4e8c\u50f9\u55ae\u5291\u75ab\u82d7\u65e9\u524d\u7372\u9999\u6e2f\u53ca\u6fb3\u9580\u885b\u751f\u90e8\u9580\u6279\u51c6\uff0c\u672c\u6708\u8d77\uff08<\/i><i>2024<\/i><i>\u5e74<\/i><i>7<\/i><i>\u6708\uff09\u4f9b\u61c9\u4e88\u9999\u6e2f<\/i><i>\u4f7f\u7528<\/i><\/li>\n<li><i>\u5e6b\u52a9<\/i><i>60<\/i><i>\u6b72\u6216\u4ee5\u4e0a\u9577\u8005\u53ca\u5b30\u5152\uff08\u65bc\u5b55\u5a66\u61f7\u5b55\u671f\u9593\u63a5\u7a2e<\/i><i>*<\/i><i>\uff09\u62b5\u6297<\/i><i>RSV<\/i><i>\u75c5\u6bd2<\/i><i><sup>1,2<\/sup><\/i><\/li>\n<li><i>\u4e8c\u50f9<\/i><i>RSV<\/i><i>\u878d\u5408\u524d<\/i><i>F<\/i><i>\u86cb\u767d\uff08<\/i><i>RSVpreF<\/i><i>\uff09\u75ab\u82d7\u70ba\u91dd\u5c0d<\/i><i>RSV<\/i><i>\u75c5\u6bd2<\/i><i>\u5e36\u4f86\u53e6\u4e00\u500b\u9078\u64c7<\/i><\/li>\n<li><i>RSV<\/i><i>\u75c5\u6bd2\u662f\u5c0e\u81f4<\/i><i>1<\/i><i>\u6b72\u4ee5\u4e0b\u5e7c\u7ae5\u4f4f\u9662\u7684\u5e38\u898b\u547c\u5438\u9053\u75c5\u6bd2\uff0c\u6b7b\u4ea1\u7387\u6bd4\u6d41\u611f\u9ad8\uff0c\u4ea6\u662f\u9999\u6e2f\u4f4f\u9662\u9577\u8005\u7684\u5e38\u898b\u81f4\u547d\u539f\u56e0<\/i><\/li>\n<\/ul>\n<p><span class=\"legendSpanClass\">\u9999\u6e2f\u548c\u6fb3\u9580<\/span><span class=\"legendSpanClass\">2024\u5e747\u670818\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u4eca\u5929\uff0c\u8f1d\u745e\u5ba3\u4f48\u65bc\u9999\u6e2f\u63a8\u51fa\u4e8c\u50f9RSVpreF\u75ab\u82d7\uff0c\u7528\u65bc\u91dd\u5c0d60\u6b72\u6216\u4ee5\u4e0a\u9577\u8005\u56e0RSV\u75c5\u6bd2\u5f15\u8d77\u7684\u4e0b\u547c\u5438\u9053\u75be\u75c5\uff08LRTD\uff09\uff0c\u4ee5\u53ca\u521d\u751f\u81f3\u516d\u500b\u6708\u5927\u5b30\u5152\uff08\u65bc\u5b55\u5a66\u61f7\u5b55\u671f\u9593\u63a5\u7a2e*\uff09\u56e0RSV\u75c5\u6bd2\u5f15\u8d77\u7684LRTD\u548c\u56b4\u91cdLRTD\u3002<sup>1<\/sup>\u8f1d\u745e\u662f\u76ee\u524d\u552f\u4e00\u4e00\u9593\u516c\u53f8\u63d0\u4f9b\u540c\u6642\u9069\u7528\u65bc\u9577\u8005\u53ca\u5b55\u5a66\u7684RSV\u75ab\u82d7\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p>RSV \u662f\u4e00\u7a2e\u50b3\u67d3\u6027\u75c5\u6bd2\uff0c\u662f\u5f15\u81f4\u5168\u7403\u5404\u5730\u547c\u5438\u7cfb\u7d71\u75be\u75c5\u7684\u5e38\u898b\u8d77\u56e0\u3002<sup>3,4<\/sup>\u00a0\u8a72\u75c5\u6bd2\u6703\u640d\u5bb3\u80ba\u90e8\u548c\u547c\u5438\u9053\uff0c\u53ef\u80fd\u5c0e\u81f4\u5b30\u5152\uff08\u5c24\u5176\u662f\u65e9\u7522\u62166\u500b\u6708\u4ee5\u4e0b\u5b30\u5152\uff09\u4ee5\u53ca\u9ad8\u98a8\u96aa\u9577\u8005\u7fa4\u7d44\u51fa\u73fe\u56b4\u91cd\u4f75\u767c\u75c7\u6216\u6b7b\u4ea1\u3002<sup>4-6<\/sup>\u00a0\u65bc2019\u5e74\uff0c\u5168\u7403\u5df2\u9304\u5f973,300\u842c\u5b97\u8207RSV\u76f8\u95dc\u7684\u6025\u6027\u4e0b\u547c\u5438\u9053\u611f\u67d3\uff0c\u5176\u4e2d101,400\u5b97\u6b7b\u4ea1\u500b\u6848\u6d89\u53ca5\u6b72\u6216\u4ee5\u4e0b\u5152\u7ae5\u3002<sup>7<\/sup>\u00a0\u81f3\u65bc65\u6b72\u6216\u4ee5\u4e0a\u9577\u8005\uff0c\u57282015\u5e74\uff0c\u5168\u7403\u75be\u75c5\u8ca0\u64d4\u6578\u5b57\u4f30\u8a08\u70ba33.6\u842c\u4eba\u5165\u9662\u300114,100\u4eba\u5728\u4f4f\u9662\u671f\u9593\u6b7b\u4ea1\u3002<sup>8 <\/sup>\u5728\u9999\u6e2f\uff0cRSV\u75c5\u6bd2\u662f\u5c0e\u81f4\u4e00\u6b72\u4ee5\u4e0b\u5e7c\u7ae5\u4f4f\u9662\u7684\u982d\u865f\u547c\u5438\u9053\u75c5\u6bd2\uff08\u4f54\u8d85\u904e\u4e00\u534a\u6848\u4f8b\uff09\uff0c<sup>9<\/sup>\u00a0\u4ea6\u662f\u4f4f\u9662\u9577\u8005\u6b7b\u4ea1\u7684\u5e38\u898b\u539f\u56e0\u3002<sup>10<\/sup><\/p>\n<p><b>\u8f1d\u745e\u9999\u6e2f\u53ca\u6fb3\u9580\u5340\u57df\u7e3d\u7d93\u7406<\/b><b><span class=\"xn-person\">Krishnamoorthy Sundaresan<\/span><\/b>\u8868\u793a\uff1a\u300c\u9019\u6b3e\u4e8c\u50f9RSVpreF\u75ab\u82d7\u5728\u5e02\u5834\u63a8\u51fa\uff0c\u518d\u4e00\u6b21\u8868\u660e\u6211\u5011\u56de\u61c9\u516c\u5171\u885b\u751f\u9700\u8981\u7684\u6c7a\u5fc3\u3002\u900f\u904e\u6b64\u75ab\u82d7\uff0c\u6211\u5011\u53ef\u70ba\u514d\u75ab\u529b\u8f03\u5f31\u7684\u7fa4\u7d44 \u2013 \u5b30\u5152\u548c\u9577\u8005\u00a0\u2013 \u63d0\u4f9b\u91dd\u5c0dRSV\u75c5\u6bd2\u7684\u4fdd\u8b77\u3002\u300d<sup>11<\/sup>\u00a0<\/p>\n<p>RSV\u75be\u75c5\u4e3b\u8981\u7531RSV A\u53caRSV B\u5169\u7a2e\u75c5\u6bd2\u4e9e\u7fa4\u5f15\u8d77\uff0c\u5169\u7a2e\u75c5\u6bd2\u53ef\u5171\u540c\u6d41\u884c\u6216\u96a8\u8457\u6bcf\u500b\u9031\u671f\u4ea4\u66ff\u4e3b\u5c0e\u3002<sup>12<\/sup>\u00a0\u9019\u6b3e\u4e8c\u50f9\u75ab\u82d7\u4e0d\u542b\u4f50\u5291\uff0c\u4e26\u7531\u5169\u7a2e\u878d\u5408\u524dF\u86cb\u767d\u7d44\u6210\uff0c\u4ee5\u767c\u63ee\u91dd\u5c0dRSV A\u548cB\u75c5\u6bd2\u7a2e\u985e\u7684\u7406\u60f3\u6548\u679c\uff0c\u4e26\u5df2\u8b49\u660e\u70ba\u5b89\u5168\u6709\u6548\u3002<sup>11<\/sup><\/p>\n<p><b>\u8f1d\u745e\u9999\u6e2f\u53ca\u6fb3\u9580\u91ab\u5b78\u7e3d\u76e3<\/b><b><span class=\"xn-person\">Eugenia Ng<\/span><\/b>\u8868\u793a\uff1a\u300c\u6b64\u75ab\u82d7\u4ea6\u914d\u5408\u9999\u6e2f\u885b\u751f\u7f72\u7684\u57fa\u5c64\u91ab\u7642\u5065\u5eb7\u85cd\u5716\uff0c\u63a8\u52d5\u9810\u9632\u52dd\u65bc\u6cbb\u7642\u7684\u6982\u5ff5\uff0c\u4ee5\u6539\u5584\u5e02\u6c11\u5065\u5eb7\u3002\u73fe\u5728\u9664\u4e86\u9577\u8005\u4e4b\u5916\uff0c\u521d\u751f\u81f3\u516d\u500b\u6708\u5927\u5b30\u5152\u4ea6\u53ef\u5f97\u5230\u4fdd\u8b77\uff0c\u5e6b\u52a9\u4ed6\u5011\u62b5\u6297\u56b4\u91cdRSV\u75be\u75c5\uff0c\u800cRSV\u75be\u75c5\u5728\u9019\u4e9b\u5b30\u5152\u4e2d\u5c0e\u81f4\u7684\u75be\u75c5\u8ca0\u64d4\u6700\u9ad8\u3002\u300d\u5728\u9999\u6e2f\uff0c\u6bcf\u5e74\u6bcf1\u842c\u540d6\u500b\u6708\u6216\u4ee5\u4e0b\u5b30\u5152\u4e2d\uff0c\u5c31\u6709233.4\u81f3311.2\u540d\u56e0\u611f\u67d3RSV\u75c5\u6bd2\u800c\u9700\u8981\u5165\u9662\u63a5\u53d7\u6cbb\u7642\u3002<sup>13<\/sup><\/p>\n<p>\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u6700\u65b0\u4e8c\u50f9RSV\u75ab\u82d7\u7684\u76f8\u95dc\u8cc7\u8a0a\uff0c\u8acb\u5411\u6240\u5c6c\u5730\u5340\u7684\u91ab\u8b77\u4eba\u54e1\u67e5\u8a62\u3002<\/p>\n<p><sup>*<\/sup>\u6709\u95dc\u5efa\u8b70\u7684\u61f7\u5b55\u9031\u671f\u63a5\u7a2e\u6642\u9593\u8868\uff0c\u8acb\u53c3\u95b1\u6240\u5c6c\u5730\u5340\u7684\u8655\u65b9\u4fe1\u606f\u3002<\/p>\n<p><b>About RSVpreF Vaccine<\/b><\/p>\n<p>Pfizer currently is the only company with an RSV vaccine to help protect older adults, as well as infants through maternal immunization. This bivalent vaccine was designed to provide broad protection against all RSV-LRTD, regardless of the virus subgroup. The RSV fusion protein (F) in the prefusion conformation is a major target of virus infection blocking antibodies and is the basis of Pfizer&#8217;s RSV vaccine. Sequence variability in F between RSV subgroup A and B strains clusters in potent neutralizing antibody binding sites on prefusion F.<\/p>\n<p><b>About Pfizer: Breakthroughs That Change Patients&#8217; Lives\u202f <\/b><\/p>\n<p>At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world&#8217;s premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For 175 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at <a href=\"http:\/\/www.pfizer.com.hk\/\" target=\"_blank\" rel=\"nofollow noopener\">www.Pfizer.com.hk<\/a>. In addition, to learn more, please visit us on <a href=\"http:\/\/www.pfizer.com.hk\/\" target=\"_blank\" rel=\"nofollow noopener\">www.Pfizer.com.hk<\/a>.\u202f<\/p>\n<p><b>References:<\/b><\/p>\n<ol type=\"1\">\n<li>Respiratory syncytial virus vaccine Prescribing Information. Pfizer Corporation Hong Kong Limited: Version <span class=\"xn-chron\">MAR 2024<\/span>.<\/li>\n<li>Respiratory syncytial virus vaccine (bivalent, recombinant) Package Leaflet. Pfizer Europe. Version: 08\/2023.<\/li>\n<li>World Health Organization. Respiratory Syncytial Virus (RSV) disease.\u00a0Available at: <a href=\"http:\/\/www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccine-standardization\/respiratory-syncytial-virus-disease%C2%A0\" target=\"_blank\" rel=\"nofollow noopener\"><span id=\"spanHghlt3a20\">www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccine-standardization\/respiratory-syncytial-virus-disease<\/span><\/a>. Accessed <span class=\"xn-chron\">May 2024<\/span>.<\/li>\n<li>Centers for Disease Control and Prevention. RSV transmission.\u00a0Available at: <a href=\"http:\/\/www.cdc.gov\/rsv\/about\/transmission.html\" target=\"_blank\" rel=\"nofollow noopener\"><span id=\"spanHghlt17b3\">www.cdc.gov\/rsv\/about\/transmission.html<\/span><\/a>. Accessed <span class=\"xn-chron\">May 2024<\/span>.<\/li>\n<li>Centers for Disease Control and Prevention. Respiratory syncytial virus infection (RSV) \u2013 Older adults are at high risk for severe RSV infection fact sheet. Available at: <a href=\"http:\/\/www.cdc.gov\/rsv\/factsheet-older-adults.pdf\" target=\"_blank\" rel=\"nofollow noopener\">www.cdc.gov\/rsv\/factsheet-older-adults.pdf<\/a>. Accessed <span class=\"xn-chron\">May 2024<\/span>.<\/li>\n<li>Centers for Disease Control and Prevention. RSV in Infants and Young Children.\u00a0Available at: <a href=\"http:\/\/www.cdc.gov\/rsv\/high-risk\/infants-young-children.html\" target=\"_blank\" rel=\"nofollow noopener\"><span id=\"spanHghlt56d8\">www.cdc.gov\/rsv\/high-risk\/infants-young-children.html<\/span><\/a>. Accessed <span class=\"xn-chron\">May 2024<\/span>.<\/li>\n<li>Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.\u00a0<i>Lancet<\/i> 2022;399:2047-2064.<\/li>\n<li>Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus-associated acute respiratory infection in older adults in 2015: A systematic review and meta-analysis. <i>J Infect Dis<\/i> 2020;222:S577-S583.<\/li>\n<li>Chan PKS, Tam WWS, Lee TC, et al. Hospitalization incidence, mortality and seasonality of common respiratory viruses over a period of 15 years in a developed subtropical city. <i>Medicine (<span class=\"xn-location\">Baltimore<\/span>) <\/i>2015;94:e2024.<\/li>\n<li>Wang Y, Fekadu G, You JHS. Comparative Cost-Effectiveness Analysis of Respiratory Syncytial Virus Vaccines for Older Adults in Hong Kong.\u00a0<i>Vaccines<\/i> 2023;11(10):1605. <a href=\"https:\/\/doi.org\/10.3390\/vaccines11101605\" rel=\"nofollow\">https:\/\/doi.org\/10.3390\/vaccines11101605<\/a><\/li>\n<li>Awosika AO, Patel P. Respiratory Syncytial Virus Prefusion F (RSVPreF3) Vaccine. [Updated 2024 Mar 19]. In: StatPearls [Internet]. <span class=\"xn-person\">Treasure Island<\/span> (FL): StatPearls Publishing; 2024 Jan-. Available from: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK594261\/\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK594261\/<\/a><\/li>\n<li>Ciarlitto, C., Vittucci, A.C., Antilici, L. et al. Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in <span class=\"xn-location\">Italy<\/span>. <i>Ital J Pediatr<\/i> 2019;45(115). <a href=\"https:\/\/doi.org\/10.1186\/s13052-019-0704-0\" rel=\"nofollow\">https:\/\/doi.org\/10.1186\/s13052-019-0704-0<\/a><\/li>\n<li>Chiu SS, Chan KH, Chen H, et al. Virologically Confirmed Population-based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in <span class=\"xn-location\">Hong Kong<\/span>. <i>Pediatr Infect Dis J<\/i>\u00a02010;29(12):1088-1092.\u00a0<\/li>\n<\/ol>\n<p>PP-A1G-HKG-0058 JUL 2024<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u9996\u500b\u53ca\u552f\u4e00\u4e00\u6b3e\u6709\u6548\u540c\u6642\u91dd\u5c0dRS&#8230;<\/p>\n","protected":false},"author":16,"featured_media":249337,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-249336","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u6700\u65b0\u4e8c\u50f9RSV\u75ab\u82d7\u7684\u76f8\u95dc\u8cc7\u8a0a\uff0c\u8acb\u5411\u6240\u5c6c\u5730\u5340\u7684\u91ab\u8b77\u4eba\u54e1\u67e5\u8a62\u3002 *\u6709\u95dc\u5efa\u8b70\u7684\u61f7\u5b55\u9031\u671f\u63a5\u7a2e\u6642\u9593\u8868\uff0c\u8acb\u53c3\u95b1\u6240\u5c6c\u5730\u5340\u7684\u8655\u65b9\u4fe1\u606f\u3002 About RSVpreF Vaccine Pfizer currently is the only company with an RSV vaccine to help protect older adults, as well as infants through maternal immunization. This bivalent vaccine was designed to provide broad protection against all RSV-LRTD, regardless of the virus subgroup. The RSV fusion protein (F) in the prefusion conformation is a major target of virus infection blocking antibodies and is the basis of Pfizer&#039;s RSV vaccine. Sequence variability in F between RSV subgroup A and B strains clusters in potent neutralizing antibody binding sites on prefusion F. About Pfizer: Breakthroughs That Change Patients&#039; Lives\u202f  At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world&#039;s premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For 175 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at www.Pfizer.com.hk. In addition, to learn more, please visit us on www.Pfizer.com.hk.\u202f References:   Respiratory syncytial virus vaccine Prescribing Information. Pfizer Corporation Hong Kong Limited: Version MAR 2024.  Respiratory syncytial virus vaccine (bivalent, recombinant) Package Leaflet. Pfizer Europe. Version: 08\/2023.  World Health Organization. Respiratory Syncytial Virus (RSV) disease.\u00a0Available at: www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccine-standardization\/respiratory-syncytial-virus-disease. Accessed May 2024.  Centers for Disease Control and Prevention. RSV transmission.\u00a0Available at: www.cdc.gov\/rsv\/about\/transmission.html. Accessed May 2024.  Centers for Disease Control and Prevention. Respiratory syncytial virus infection (RSV) \u2013 Older adults are at high risk for severe RSV infection fact sheet. Available at: www.cdc.gov\/rsv\/factsheet-older-adults.pdf. Accessed May 2024.  Centers for Disease Control and Prevention. RSV in Infants and Young Children.\u00a0Available at: www.cdc.gov\/rsv\/high-risk\/infants-young-children.html. Accessed May 2024.  Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.\u00a0Lancet 2022;399:2047-2064.  Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus-associated acute respiratory infection in older adults in 2015: A systematic review and meta-analysis. J Infect Dis 2020;222:S577-S583.  Chan PKS, Tam WWS, Lee TC, et al. Hospitalization incidence, mortality and seasonality of common respiratory viruses over a period of 15 years in a developed subtropical city. Medicine (Baltimore) 2015;94:e2024.  Wang Y, Fekadu G, You JHS. Comparative Cost-Effectiveness Analysis of Respiratory Syncytial Virus Vaccines for Older Adults in Hong Kong.\u00a0Vaccines 2023;11(10):1605. https:\/\/doi.org\/10.3390\/vaccines11101605  Awosika AO, Patel P. Respiratory Syncytial Virus Prefusion F (RSVPreF3) Vaccine. . In: StatPearls . Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK594261\/  Ciarlitto, C., Vittucci, A.C., Antilici, L. et al. Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in Italy. Ital J Pediatr 2019;45(115). https:\/\/doi.org\/10.1186\/s13052-019-0704-0  Chiu SS, Chan KH, Chen H, et al. Virologically Confirmed Population-based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong. 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B\u5169\u7a2e\u75c5\u6bd2\u4e9e\u7fa4\u5f15\u8d77\uff0c\u5169\u7a2e\u75c5\u6bd2\u53ef\u5171\u540c\u6d41\u884c\u6216\u96a8\u8457\u6bcf\u500b\u9031\u671f\u4ea4\u66ff\u4e3b\u5c0e\u300212\u00a0\u9019\u6b3e\u4e8c\u50f9\u75ab\u82d7\u4e0d\u542b\u4f50\u5291\uff0c\u4e26\u7531\u5169\u7a2e\u878d\u5408\u524dF\u86cb\u767d\u7d44\u6210\uff0c\u4ee5\u767c\u63ee\u91dd\u5c0dRSV A\u548cB\u75c5\u6bd2\u7a2e\u985e\u7684\u7406\u60f3\u6548\u679c\uff0c\u4e26\u5df2\u8b49\u660e\u70ba\u5b89\u5168\u6709\u6548\u300211 \u8f1d\u745e\u9999\u6e2f\u53ca\u6fb3\u9580\u91ab\u5b78\u7e3d\u76e3Eugenia Ng\u8868\u793a\uff1a\u300c\u6b64\u75ab\u82d7\u4ea6\u914d\u5408\u9999\u6e2f\u885b\u751f\u7f72\u7684\u57fa\u5c64\u91ab\u7642\u5065\u5eb7\u85cd\u5716\uff0c\u63a8\u52d5\u9810\u9632\u52dd\u65bc\u6cbb\u7642\u7684\u6982\u5ff5\uff0c\u4ee5\u6539\u5584\u5e02\u6c11\u5065\u5eb7\u3002\u73fe\u5728\u9664\u4e86\u9577\u8005\u4e4b\u5916\uff0c\u521d\u751f\u81f3\u516d\u500b\u6708\u5927\u5b30\u5152\u4ea6\u53ef\u5f97\u5230\u4fdd\u8b77\uff0c\u5e6b\u52a9\u4ed6\u5011\u62b5\u6297\u56b4\u91cdRSV\u75be\u75c5\uff0c\u800cRSV\u75be\u75c5\u5728\u9019\u4e9b\u5b30\u5152\u4e2d\u5c0e\u81f4\u7684\u75be\u75c5\u8ca0\u64d4\u6700\u9ad8\u3002\u300d\u5728\u9999\u6e2f\uff0c\u6bcf\u5e74\u6bcf1\u842c\u540d6\u500b\u6708\u6216\u4ee5\u4e0b\u5b30\u5152\u4e2d\uff0c\u5c31\u6709233.4\u81f3311.2\u540d\u56e0\u611f\u67d3RSV\u75c5\u6bd2\u800c\u9700\u8981\u5165\u9662\u63a5\u53d7\u6cbb\u7642\u300213 \u5982\u6b32\u4e86\u89e3\u66f4\u591a\u6700\u65b0\u4e8c\u50f9RSV\u75ab\u82d7\u7684\u76f8\u95dc\u8cc7\u8a0a\uff0c\u8acb\u5411\u6240\u5c6c\u5730\u5340\u7684\u91ab\u8b77\u4eba\u54e1\u67e5\u8a62\u3002 *\u6709\u95dc\u5efa\u8b70\u7684\u61f7\u5b55\u9031\u671f\u63a5\u7a2e\u6642\u9593\u8868\uff0c\u8acb\u53c3\u95b1\u6240\u5c6c\u5730\u5340\u7684\u8655\u65b9\u4fe1\u606f\u3002 About RSVpreF Vaccine Pfizer currently is the only company with an RSV vaccine to help protect older adults, as well as infants through maternal immunization. This bivalent vaccine was designed to provide broad protection against all RSV-LRTD, regardless of the virus subgroup. The RSV fusion protein (F) in the prefusion conformation is a major target of virus infection blocking antibodies and is the basis of Pfizer&#039;s RSV vaccine. Sequence variability in F between RSV subgroup A and B strains clusters in potent neutralizing antibody binding sites on prefusion F. About Pfizer: Breakthroughs That Change Patients&#039; Lives\u202f  At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world&#039;s premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For 175 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at www.Pfizer.com.hk. In addition, to learn more, please visit us on www.Pfizer.com.hk.\u202f References:   Respiratory syncytial virus vaccine Prescribing Information. Pfizer Corporation Hong Kong Limited: Version MAR 2024.  Respiratory syncytial virus vaccine (bivalent, recombinant) Package Leaflet. Pfizer Europe. Version: 08\/2023.  World Health Organization. Respiratory Syncytial Virus (RSV) disease.\u00a0Available at: www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccine-standardization\/respiratory-syncytial-virus-disease. Accessed May 2024.  Centers for Disease Control and Prevention. RSV transmission.\u00a0Available at: www.cdc.gov\/rsv\/about\/transmission.html. Accessed May 2024.  Centers for Disease Control and Prevention. Respiratory syncytial virus infection (RSV) \u2013 Older adults are at high risk for severe RSV infection fact sheet. Available at: www.cdc.gov\/rsv\/factsheet-older-adults.pdf. Accessed May 2024.  Centers for Disease Control and Prevention. RSV in Infants and Young Children.\u00a0Available at: www.cdc.gov\/rsv\/high-risk\/infants-young-children.html. Accessed May 2024.  Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.\u00a0Lancet 2022;399:2047-2064.  Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus-associated acute respiratory infection in older adults in 2015: A systematic review and meta-analysis. J Infect Dis 2020;222:S577-S583.  Chan PKS, Tam WWS, Lee TC, et al. Hospitalization incidence, mortality and seasonality of common respiratory viruses over a period of 15 years in a developed subtropical city. Medicine (Baltimore) 2015;94:e2024.  Wang Y, Fekadu G, You JHS. Comparative Cost-Effectiveness Analysis of Respiratory Syncytial Virus Vaccines for Older Adults in Hong Kong.\u00a0Vaccines 2023;11(10):1605. https:\/\/doi.org\/10.3390\/vaccines11101605  Awosika AO, Patel P. Respiratory Syncytial Virus Prefusion F (RSVPreF3) Vaccine. . In: StatPearls . Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK594261\/  Ciarlitto, C., Vittucci, A.C., Antilici, L. et al. Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in Italy. Ital J Pediatr 2019;45(115). https:\/\/doi.org\/10.1186\/s13052-019-0704-0  Chiu SS, Chan KH, Chen H, et al. Virologically Confirmed Population-based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong. 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\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u6700\u65b0\u4e8c\u50f9RSV\u75ab\u82d7\u7684\u76f8\u95dc\u8cc7\u8a0a\uff0c\u8acb\u5411\u6240\u5c6c\u5730\u5340\u7684\u91ab\u8b77\u4eba\u54e1\u67e5\u8a62\u3002 *\u6709\u95dc\u5efa\u8b70\u7684\u61f7\u5b55\u9031\u671f\u63a5\u7a2e\u6642\u9593\u8868\uff0c\u8acb\u53c3\u95b1\u6240\u5c6c\u5730\u5340\u7684\u8655\u65b9\u4fe1\u606f\u3002 About RSVpreF Vaccine Pfizer currently is the only company with an RSV vaccine to help protect older adults, as well as infants through maternal immunization. This bivalent vaccine was designed to provide broad protection against all RSV-LRTD, regardless of the virus subgroup. The RSV fusion protein (F) in the prefusion conformation is a major target of virus infection blocking antibodies and is the basis of Pfizer's RSV vaccine. Sequence variability in F between RSV subgroup A and B strains clusters in potent neutralizing antibody binding sites on prefusion F. About Pfizer: Breakthroughs That Change Patients' Lives\u202f At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For 175 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at www.Pfizer.com.hk. In addition, to learn more, please visit us on www.Pfizer.com.hk.\u202f References: Respiratory syncytial virus vaccine Prescribing Information. Pfizer Corporation Hong Kong Limited: Version MAR 2024. Respiratory syncytial virus vaccine (bivalent, recombinant) Package Leaflet. Pfizer Europe. Version: 08\\\/2023. World Health Organization. Respiratory Syncytial Virus (RSV) disease.\u00a0Available at: www.who.int\\\/teams\\\/health-product-policy-and-standards\\\/standards-and-specifications\\\/vaccine-standardization\\\/respiratory-syncytial-virus-disease. Accessed May 2024. Centers for Disease Control and Prevention. RSV transmission.\u00a0Available at: www.cdc.gov\\\/rsv\\\/about\\\/transmission.html. Accessed May 2024. Centers for Disease Control and Prevention. Respiratory syncytial virus infection (RSV) \u2013 Older adults are at high risk for severe RSV infection fact sheet. Available at: www.cdc.gov\\\/rsv\\\/factsheet-older-adults.pdf. Accessed May 2024. Centers for Disease Control and Prevention. RSV in Infants and Young Children.\u00a0Available at: www.cdc.gov\\\/rsv\\\/high-risk\\\/infants-young-children.html. Accessed May 2024. Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.\u00a0Lancet 2022;399:2047-2064. Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus-associated acute respiratory infection in older adults in 2015: A systematic review and meta-analysis. J Infect Dis 2020;222:S577-S583. Chan PKS, Tam WWS, Lee TC, et al. Hospitalization incidence, mortality and seasonality of common respiratory viruses over a period of 15 years in a developed subtropical city. Medicine (Baltimore) 2015;94:e2024. Wang Y, Fekadu G, You JHS. Comparative Cost-Effectiveness Analysis of Respiratory Syncytial Virus Vaccines for Older Adults in Hong Kong.\u00a0Vaccines 2023;11(10):1605. https:\\\/\\\/doi.org\\\/10.3390\\\/vaccines11101605 Awosika AO, Patel P. Respiratory Syncytial Virus Prefusion F (RSVPreF3) Vaccine. . In: StatPearls . Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https:\\\/\\\/www.ncbi.nlm.nih.gov\\\/books\\\/NBK594261\\\/ Ciarlitto, C., Vittucci, A.C., Antilici, L. et al. Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in Italy. Ital J Pediatr 2019;45(115). https:\\\/\\\/doi.org\\\/10.1186\\\/s13052-019-0704-0 Chiu SS, Chan KH, Chen H, et al. Virologically Confirmed Population-based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong. 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\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u6700\u65b0\u4e8c\u50f9RSV\u75ab\u82d7\u7684\u76f8\u95dc\u8cc7\u8a0a\uff0c\u8acb\u5411\u6240\u5c6c\u5730\u5340\u7684\u91ab\u8b77\u4eba\u54e1\u67e5\u8a62\u3002 *\u6709\u95dc\u5efa\u8b70\u7684\u61f7\u5b55\u9031\u671f\u63a5\u7a2e\u6642\u9593\u8868\uff0c\u8acb\u53c3\u95b1\u6240\u5c6c\u5730\u5340\u7684\u8655\u65b9\u4fe1\u606f\u3002 About RSVpreF Vaccine Pfizer currently is the only company with an RSV vaccine to help protect older adults, as well as infants through maternal immunization. This bivalent vaccine was designed to provide broad protection against all RSV-LRTD, regardless of the virus subgroup. The RSV fusion protein (F) in the prefusion conformation is a major target of virus infection blocking antibodies and is the basis of Pfizer's RSV vaccine. Sequence variability in F between RSV subgroup A and B strains clusters in potent neutralizing antibody binding sites on prefusion F. About Pfizer: Breakthroughs That Change Patients' Lives\u202f  At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For 175 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at www.Pfizer.com.hk. In addition, to learn more, please visit us on www.Pfizer.com.hk.\u202f References:   Respiratory syncytial virus vaccine Prescribing Information. Pfizer Corporation Hong Kong Limited: Version MAR 2024.  Respiratory syncytial virus vaccine (bivalent, recombinant) Package Leaflet. Pfizer Europe. Version: 08\/2023.  World Health Organization. Respiratory Syncytial Virus (RSV) disease.\u00a0Available at: www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccine-standardization\/respiratory-syncytial-virus-disease. Accessed May 2024.  Centers for Disease Control and Prevention. RSV transmission.\u00a0Available at: www.cdc.gov\/rsv\/about\/transmission.html. Accessed May 2024.  Centers for Disease Control and Prevention. Respiratory syncytial virus infection (RSV) \u2013 Older adults are at high risk for severe RSV infection fact sheet. Available at: www.cdc.gov\/rsv\/factsheet-older-adults.pdf. Accessed May 2024.  Centers for Disease Control and Prevention. RSV in Infants and Young Children.\u00a0Available at: www.cdc.gov\/rsv\/high-risk\/infants-young-children.html. Accessed May 2024.  Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.\u00a0Lancet 2022;399:2047-2064.  Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus-associated acute respiratory infection in older adults in 2015: A systematic review and meta-analysis. J Infect Dis 2020;222:S577-S583.  Chan PKS, Tam WWS, Lee TC, et al. Hospitalization incidence, mortality and seasonality of common respiratory viruses over a period of 15 years in a developed subtropical city. Medicine (Baltimore) 2015;94:e2024.  Wang Y, Fekadu G, You JHS. Comparative Cost-Effectiveness Analysis of Respiratory Syncytial Virus Vaccines for Older Adults in Hong Kong.\u00a0Vaccines 2023;11(10):1605. https:\/\/doi.org\/10.3390\/vaccines11101605  Awosika AO, Patel P. Respiratory Syncytial Virus Prefusion F (RSVPreF3) Vaccine. . In: StatPearls . Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK594261\/  Ciarlitto, C., Vittucci, A.C., Antilici, L. et al. Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in Italy. Ital J Pediatr 2019;45(115). https:\/\/doi.org\/10.1186\/s13052-019-0704-0  Chiu SS, Chan KH, Chen H, et al. Virologically Confirmed Population-based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong. Pediatr Infect Dis J\u00a02010;29(12):1088-1092.\u00a0  PP-A1G-HKG-0058 JUL 2024","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pingtungtimes.com.tw\/?p=249336","og_locale":"zh_TW","og_type":"article","og_title":"\u8f1d\u745e\u5ba3\u4f48\u672c\u6708\u8d77\u4f9b\u61c9\u9996\u6b3e\u64c1\u6709\u96d9\u9069\u61c9\u75c7\u7684\u547c\u5438\u9053\u5408\u80de\u75c5\u6bd2\u75ab\u82d7\u4e88\u9999\u6e2f - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","og_description":"\u9996\u500b\u53ca\u552f\u4e00\u4e00\u6b3e\u6709\u6548\u540c\u6642\u91dd\u5c0dRSV A\u53caRSV B\u75c5\u6bd2\u7684\u4e8c\u50f9\u55ae\u5291\u75ab\u82d7\u65e9\u524d\u7372\u9999\u6e2f\u53ca\u6fb3\u9580\u885b\u751f\u90e8\u9580\u6279\u51c6\uff0c\u672c\u6708\u8d77\uff082024\u5e747\u6708\uff09\u4f9b\u61c9\u4e88\u9999\u6e2f\u4f7f\u7528  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\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u6700\u65b0\u4e8c\u50f9RSV\u75ab\u82d7\u7684\u76f8\u95dc\u8cc7\u8a0a\uff0c\u8acb\u5411\u6240\u5c6c\u5730\u5340\u7684\u91ab\u8b77\u4eba\u54e1\u67e5\u8a62\u3002 *\u6709\u95dc\u5efa\u8b70\u7684\u61f7\u5b55\u9031\u671f\u63a5\u7a2e\u6642\u9593\u8868\uff0c\u8acb\u53c3\u95b1\u6240\u5c6c\u5730\u5340\u7684\u8655\u65b9\u4fe1\u606f\u3002 About RSVpreF Vaccine Pfizer currently is the only company with an RSV vaccine to help protect older adults, as well as infants through maternal immunization. This bivalent vaccine was designed to provide broad protection against all RSV-LRTD, regardless of the virus subgroup. The RSV fusion protein (F) in the prefusion conformation is a major target of virus infection blocking antibodies and is the basis of Pfizer's RSV vaccine. Sequence variability in F between RSV subgroup A and B strains clusters in potent neutralizing antibody binding sites on prefusion F. About Pfizer: Breakthroughs That Change Patients' Lives\u202f  At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For 175 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at www.Pfizer.com.hk. In addition, to learn more, please visit us on www.Pfizer.com.hk.\u202f References:   Respiratory syncytial virus vaccine Prescribing Information. Pfizer Corporation Hong Kong Limited: Version MAR 2024.  Respiratory syncytial virus vaccine (bivalent, recombinant) Package Leaflet. Pfizer Europe. Version: 08\/2023.  World Health Organization. Respiratory Syncytial Virus (RSV) disease.\u00a0Available at: www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccine-standardization\/respiratory-syncytial-virus-disease. Accessed May 2024.  Centers for Disease Control and Prevention. RSV transmission.\u00a0Available at: www.cdc.gov\/rsv\/about\/transmission.html. Accessed May 2024.  Centers for Disease Control and Prevention. Respiratory syncytial virus infection (RSV) \u2013 Older adults are at high risk for severe RSV infection fact sheet. Available at: www.cdc.gov\/rsv\/factsheet-older-adults.pdf. Accessed May 2024.  Centers for Disease Control and Prevention. RSV in Infants and Young Children.\u00a0Available at: www.cdc.gov\/rsv\/high-risk\/infants-young-children.html. Accessed May 2024.  Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.\u00a0Lancet 2022;399:2047-2064.  Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus-associated acute respiratory infection in older adults in 2015: A systematic review and meta-analysis. J Infect Dis 2020;222:S577-S583.  Chan PKS, Tam WWS, Lee TC, et al. Hospitalization incidence, mortality and seasonality of common respiratory viruses over a period of 15 years in a developed subtropical city. Medicine (Baltimore) 2015;94:e2024.  Wang Y, Fekadu G, You JHS. Comparative Cost-Effectiveness Analysis of Respiratory Syncytial Virus Vaccines for Older Adults in Hong Kong.\u00a0Vaccines 2023;11(10):1605. https:\/\/doi.org\/10.3390\/vaccines11101605  Awosika AO, Patel P. Respiratory Syncytial Virus Prefusion F (RSVPreF3) Vaccine. . In: StatPearls . Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK594261\/  Ciarlitto, C., Vittucci, A.C., Antilici, L. et al. Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in Italy. Ital J Pediatr 2019;45(115). https:\/\/doi.org\/10.1186\/s13052-019-0704-0  Chiu SS, Chan KH, Chen H, et al. Virologically Confirmed Population-based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong. 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\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u6700\u65b0\u4e8c\u50f9RSV\u75ab\u82d7\u7684\u76f8\u95dc\u8cc7\u8a0a\uff0c\u8acb\u5411\u6240\u5c6c\u5730\u5340\u7684\u91ab\u8b77\u4eba\u54e1\u67e5\u8a62\u3002 *\u6709\u95dc\u5efa\u8b70\u7684\u61f7\u5b55\u9031\u671f\u63a5\u7a2e\u6642\u9593\u8868\uff0c\u8acb\u53c3\u95b1\u6240\u5c6c\u5730\u5340\u7684\u8655\u65b9\u4fe1\u606f\u3002 About RSVpreF Vaccine Pfizer currently is the only company with an RSV vaccine to help protect older adults, as well as infants through maternal immunization. This bivalent vaccine was designed to provide broad protection against all RSV-LRTD, regardless of the virus subgroup. The RSV fusion protein (F) in the prefusion conformation is a major target of virus infection blocking antibodies and is the basis of Pfizer's RSV vaccine. Sequence variability in F between RSV subgroup A and B strains clusters in potent neutralizing antibody binding sites on prefusion F. About Pfizer: Breakthroughs That Change Patients' Lives\u202f At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products, including innovative medicines and vaccines. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For 175 years, we have worked to make a difference for all who rely on us. We routinely post information that may be important to investors on our website at www.Pfizer.com.hk. In addition, to learn more, please visit us on www.Pfizer.com.hk.\u202f References: Respiratory syncytial virus vaccine Prescribing Information. Pfizer Corporation Hong Kong Limited: Version MAR 2024. Respiratory syncytial virus vaccine (bivalent, recombinant) Package Leaflet. Pfizer Europe. Version: 08\/2023. World Health Organization. Respiratory Syncytial Virus (RSV) disease.\u00a0Available at: www.who.int\/teams\/health-product-policy-and-standards\/standards-and-specifications\/vaccine-standardization\/respiratory-syncytial-virus-disease. Accessed May 2024. Centers for Disease Control and Prevention. RSV transmission.\u00a0Available at: www.cdc.gov\/rsv\/about\/transmission.html. Accessed May 2024. Centers for Disease Control and Prevention. Respiratory syncytial virus infection (RSV) \u2013 Older adults are at high risk for severe RSV infection fact sheet. Available at: www.cdc.gov\/rsv\/factsheet-older-adults.pdf. Accessed May 2024. Centers for Disease Control and Prevention. RSV in Infants and Young Children.\u00a0Available at: www.cdc.gov\/rsv\/high-risk\/infants-young-children.html. Accessed May 2024. Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis.\u00a0Lancet 2022;399:2047-2064. Shi T, Denouel A, Tietjen AK, et al. Global disease burden estimates of respiratory syncytial virus-associated acute respiratory infection in older adults in 2015: A systematic review and meta-analysis. J Infect Dis 2020;222:S577-S583. Chan PKS, Tam WWS, Lee TC, et al. Hospitalization incidence, mortality and seasonality of common respiratory viruses over a period of 15 years in a developed subtropical city. Medicine (Baltimore) 2015;94:e2024. Wang Y, Fekadu G, You JHS. Comparative Cost-Effectiveness Analysis of Respiratory Syncytial Virus Vaccines for Older Adults in Hong Kong.\u00a0Vaccines 2023;11(10):1605. https:\/\/doi.org\/10.3390\/vaccines11101605 Awosika AO, Patel P. Respiratory Syncytial Virus Prefusion F (RSVPreF3) Vaccine. . In: StatPearls . Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK594261\/ Ciarlitto, C., Vittucci, A.C., Antilici, L. et al. Respiratory Syncityal Virus A and B: three bronchiolitis seasons in a third level hospital in Italy. Ital J Pediatr 2019;45(115). https:\/\/doi.org\/10.1186\/s13052-019-0704-0 Chiu SS, Chan KH, Chen H, et al. Virologically Confirmed Population-based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong. 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