{"id":235391,"date":"2024-05-07T08:10:00","date_gmt":"2024-05-07T00:10:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=235391"},"modified":"2024-05-07T08:10:00","modified_gmt":"2024-05-07T00:10:00","slug":"%e4%bf%a1%e9%81%94%e7%94%9f%e7%89%a9ibi343-cldn-18-2-adc-%e7%8d%b2%e5%9c%8b%e5%ae%b6%e8%97%a5%e5%93%81%e7%9b%a3%e7%9d%a3%e7%ae%a1%e7%90%86%e5%b1%80%e7%b4%8d%e5%85%a5%e7%aa%81%e7%a0%b4%e6%80%a7","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=235391","title":{"rendered":"\u4fe1\u9054\u751f\u7269IBI343 (CLDN 18.2 ADC) \u7372\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u7d0d\u5165\u7a81\u7834\u6027\u6cbb\u7642\u85e5\u7269\u54c1\u7a2e\uff0c\u6cbb\u7642\u665a\u671f\u80c3\/\u80c3\u98df\u7ba1\u4ea4\u754c\u8655\u817a\u764c\u60a3\u8005"},"content":{"rendered":"<div>\n<p>\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde2024\u5e745\u67087\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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href=\"https:\/\/www.cde.org.cn\/main\/xxgk\/listpage\/da6efd086c099b7fc949121166f0130c\" target=\"_blank\" rel=\"nofollow noopener\">\u9019\u88e1<\/a>\u67e5\u770b\u5df2\u7d0d\u5165\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\u540d\u55ae\u3002<\/p>\n<p><b>\u95dc\u65bc\u80c3<\/b><b>\/<\/b><b>\u80c3\u98df\u7ba1\u4ea4\u754c\u8655\u817a\u764c<\/b><\/p>\n<p>\u80c3\u764c\u662f\u4e16\u754c\u4e0a\u6700\u5e38\u898b\u7684\u60e1\u6027\u816b\u7624\u4e4b\u4e00\uff0c\u662f\u5168\u7403\u8303\u570d\u5167\u56e0\u764c\u75c7\u5c0e\u81f4\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\u3002\u8f49\u79fb\u6027\u80c3\u764c\u60a3\u80055\u5e74\u751f\u5b58\u7387\u4e0d\u8db3 5%<sup>[i]<\/sup>\u3002\u4e2d\u570b\u3001\u65e5\u672c\u7b49\u662f\u80c3\u764c\u9ad8\u767c\u5340<sup>[ii]<\/sup>\u3002\u76ee\u524d\uff0c\u6c1f\u5627\u5576\u548c\u9251\u985e\u806f\u5408\u6cbb\u7642\u7684\u5316\u7642\u53ca\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u6cbb\u7642\u662f\u665a\u671f\u8f49\u79fb\u6027\u80c3\u764c\u60a3\u8005\u7684\u6a19\u51c6\u6cbb\u7642\u3002\u7cfb\u7d71\u6027\u6cbb\u7642\u5c0d\u665a\u671f\u80c3\u764c\u7684\u7642\u6548\u6709\u9650\uff0c\u5c24\u5176\u5c0d\u65bc\u4e09\u7dda\u53ca\u4ee5\u4e0a\u80c3\u764c\u60a3\u8005\u7684\u9810\u5f8c\u901a\u5e38\u8f03\u5dee\uff0c\u53ef\u9078\u7684\u6cbb\u7642\u624b\u6bb5\u5c11\uff0c\u9810\u671f\u751f\u5b58\u8f03\u77ed\uff0c\u4e2d\u4f4d\u751f\u5b58\u671f\u7d04\u534a\u5e74<sup>[iii]<\/sup>\u3002<\/p>\n<p>\u7dca\u5bc6\u9023\u63a5\u5206\u5b50\u5bb6\u65cf\u6210\u54e1\u00a0Claudin 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href=\"http:\/\/www.innoventbio.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.innoventbio.com<\/a>\u6216\u516c\u53f8\u9818\u82f1\u8cec\u865fwww.linkedin.com\/company\/innovent-biologics\/\u3002<\/p>\n<p><i>\u8072\u660e\uff1a<\/i><i>1.\u4fe1\u9054\u751f\u7269\u4e0d\u63a8\u85a6\u672a\u7372\u6279\u7684\u85e5\u54c1\/\u9069\u61c9\u75c7\u7684\u4f7f\u7528\u3002<br 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(a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002<\/p>\n<p>\u53c3\u8003\u6587\u737b<\/p>\n<div>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">[i] Lasithiotakis K, Antoniou SA, Antoniou GA, Kaklamanos I, Zoras O. Gastrectomy for stage IV gastric cancer. a systematic review and meta-analysis. Anticancer Res. May 2014;34(5):2079-85<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">[ii] Xu B, Wang JM. Epidemiological study of gastric cancer[J]. Chin J Cancer Prev Treat, 2006,13(1): 81-87.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">[iii]\u00a0Chan WL, Lam KO, So TH, et al. Third-line systemic treatment in advanced\/metastatic gastric cancer: a comprehensive review. Ther Adv Med Oncol. 2019;11:1758835919859990.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">[iv]\u00a0Sahin U, Koslowski M, Dhaene K, et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. Clin Cancer Res. 2008;14(23):7624-7634.<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>\u00a0<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde2024\u5e74&#8230;<\/p>\n","protected":false},"author":16,"featured_media":199219,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-235391","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u4fe1\u9054\u751f\u7269IBI343 (CLDN 18.2 ADC) 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\u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u96c7\u54e1\u4ee3\u7406\u6982\u4e0d\u627f\u64d4 (a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002 \u53c3\u8003\u6587\u737b           Lasithiotakis K, Antoniou SA, Antoniou GA, Kaklamanos I, Zoras O. Gastrectomy for stage IV gastric cancer. a systematic review and meta-analysis. Anticancer Res. May 2014;34(5):2079-85         Xu B, Wang JM. Epidemiological study of gastric cancer. Chin J Cancer Prev Treat, 2006,13(1): 81-87.         \u00a0Chan WL, Lam KO, So TH, et al. Third-line systemic treatment in advanced\/metastatic gastric cancer: a comprehensive review. Ther Adv Med Oncol. 2019;11:1758835919859990.         \u00a0Sahin U, Koslowski M, Dhaene K, et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. Clin Cancer Res. 2008;14(23):7624-7634.         \u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=235391\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u4fe1\u9054\u751f\u7269IBI343 (CLDN 18.2 ADC) \u7372\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u7d0d\u5165\u7a81\u7834\u6027\u6cbb\u7642\u85e5\u7269\u54c1\u7a2e\uff0c\u6cbb\u7642\u665a\u671f\u80c3\/\u80c3\u98df\u7ba1\u4ea4\u754c\u8655\u817a\u764c\u60a3\u8005 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde2024\u5e745\u67087\u65e5 \/\u7f8e\u901a\u793e\/ -- 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\u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u96c7\u54e1\u4ee3\u7406\u6982\u4e0d\u627f\u64d4 (a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002 \u53c3\u8003\u6587\u737b           Lasithiotakis K, Antoniou SA, Antoniou GA, Kaklamanos I, Zoras O. Gastrectomy for stage IV gastric cancer. a systematic review and meta-analysis. Anticancer Res. May 2014;34(5):2079-85         Xu B, Wang JM. Epidemiological study of gastric cancer. Chin J Cancer Prev Treat, 2006,13(1): 81-87.         \u00a0Chan WL, Lam KO, So TH, et al. Third-line systemic treatment in advanced\/metastatic gastric cancer: a comprehensive review. Ther Adv Med Oncol. 2019;11:1758835919859990.         \u00a0Sahin U, Koslowski M, Dhaene K, et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. 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Gastrectomy for stage IV gastric cancer. a systematic review and meta-analysis. Anticancer Res. May 2014;34(5):2079-85 Xu B, Wang JM. Epidemiological study of gastric cancer. Chin J Cancer Prev Treat, 2006,13(1): 81-87. \u00a0Chan WL, Lam KO, So TH, et al. Third-line systemic treatment in advanced\\\/metastatic gastric cancer: a comprehensive review. Ther Adv Med Oncol. 2019;11:1758835919859990. \u00a0Sahin U, Koslowski M, Dhaene K, et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. 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\u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u96c7\u54e1\u4ee3\u7406\u6982\u4e0d\u627f\u64d4 (a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002 \u53c3\u8003\u6587\u737b           Lasithiotakis K, Antoniou SA, Antoniou GA, Kaklamanos I, Zoras O. Gastrectomy for stage IV gastric cancer. a systematic review and meta-analysis. Anticancer Res. May 2014;34(5):2079-85         Xu B, Wang JM. Epidemiological study of gastric cancer. Chin J Cancer Prev Treat, 2006,13(1): 81-87.         \u00a0Chan WL, Lam KO, So TH, et al. Third-line systemic treatment in advanced\/metastatic gastric cancer: a comprehensive review. Ther Adv Med Oncol. 2019;11:1758835919859990.         \u00a0Sahin U, Koslowski M, Dhaene K, et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. Clin Cancer Res. 2008;14(23):7624-7634.         \u00a0","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pingtungtimes.com.tw\/?p=235391","og_locale":"zh_TW","og_type":"article","og_title":"\u4fe1\u9054\u751f\u7269IBI343 (CLDN 18.2 ADC) \u7372\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u7d0d\u5165\u7a81\u7834\u6027\u6cbb\u7642\u85e5\u7269\u54c1\u7a2e\uff0c\u6cbb\u7642\u665a\u671f\u80c3\/\u80c3\u98df\u7ba1\u4ea4\u754c\u8655\u817a\u764c\u60a3\u8005 - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","og_description":"\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde2024\u5e745\u67087\u65e5 \/\u7f8e\u901a\u793e\/ -- 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\u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u96c7\u54e1\u4ee3\u7406\u6982\u4e0d\u627f\u64d4 (a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002 \u53c3\u8003\u6587\u737b           Lasithiotakis K, Antoniou SA, Antoniou GA, Kaklamanos I, Zoras O. Gastrectomy for stage IV gastric cancer. a systematic review and meta-analysis. Anticancer Res. May 2014;34(5):2079-85         Xu B, Wang JM. Epidemiological study of gastric cancer. Chin J Cancer Prev Treat, 2006,13(1): 81-87.         \u00a0Chan WL, Lam KO, So TH, et al. Third-line systemic treatment in advanced\/metastatic gastric cancer: a comprehensive review. Ther Adv Med Oncol. 2019;11:1758835919859990.         \u00a0Sahin U, Koslowski M, Dhaene K, et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. 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Gastrectomy for stage IV gastric cancer. a systematic review and meta-analysis. Anticancer Res. May 2014;34(5):2079-85 Xu B, Wang JM. Epidemiological study of gastric cancer. Chin J Cancer Prev Treat, 2006,13(1): 81-87. \u00a0Chan WL, Lam KO, So TH, et al. Third-line systemic treatment in advanced\/metastatic gastric cancer: a comprehensive review. Ther Adv Med Oncol. 2019;11:1758835919859990. \u00a0Sahin U, Koslowski M, Dhaene K, et al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. 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