{"id":210721,"date":"2024-01-11T00:34:00","date_gmt":"2024-01-10T16:34:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=210721"},"modified":"2024-01-11T00:34:00","modified_gmt":"2024-01-10T16:34:00","slug":"venatorx-pharmaceuticals-%e8%88%87-menarini-group-%e9%81%94%e6%88%90%e5%95%86%e6%a5%ad%e5%8d%94%e8%ad%b0%ef%bc%8c%e5%9c%a8-96-%e5%80%8b%e5%9c%8b%e5%ae%b6%e6%8e%a8%e5%87%ba-cefepime-taniborbactam","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=210721","title":{"rendered":"Venatorx Pharmaceuticals \u8207 Menarini Group \u9054\u6210\u5546\u696d\u5354\u8b70\uff0c\u5728 96 \u500b\u570b\u5bb6\u63a8\u51fa Cefepime-Taniborbactam"},"content":{"rendered":"
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\u7f8e\u570b\u8cd3\u5915\u51e1\u5c3c\u4e9e\u5dde\u83ab\u723e\u6587\u53ca\u610f\u5927\u5229\u4f5b\u7f85\u502b\u65af<\/span>2024\u5e741\u670811\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — Venatorx Pharmaceuticals \u662f\u4e00\u5bb6\u79c1\u71df\u3001\u5546\u696d\u5316\u524d\u671f\u7684\u88fd\u85e5\u516c\u53f8\uff0c\u5c08\u6ce8\u65bc\u6539\u5584\u591a\u91cd\u8010\u85e5\u6027\u7d30\u83cc\u611f\u67d3\u548c\u96e3\u4ee5\u6cbb\u7642\u7684\u75c5\u6bd2\u611f\u67d3\u60a3\u8005\u4e4b\u5065\u5eb7\u3002\u8a72\u516c\u53f8\u8207\u610f\u5927\u5229\u751f\u7269\u88fd\u85e5\u96c6\u5718 Menarini Group \u4eca\u65e5\u5ba3\u4f48\u4ed6\u5011\u5df2\u9054\u6210\u5354\u8b70\uff0cMenarini \u5c07\u6703\u7372\u5f97\u7368\u5bb6\u6b0a\u5229\uff0c\u53ef\u65bc\u6b50\u6d32\u3001\u62c9\u4e01\u7f8e\u6d32\u3001\u4e2d\u6771\u3001\u571f\u8033\u5176\u3001\u5317\u975e\u548c\u7368\u7acb\u570b\u5bb6\u806f\u5408\u9ad4 (CIS) \u7684 96 \u500b\u570b\u5bb6\uff0c\u5728\u53d6\u5f97\u76f8\u95dc\u885b\u751f\u90e8\u9580\u7684\u6279\u51c6\u5f8c\uff0c\u5c07 cefepime-taniborbactam \u5546\u54c1\u5316\u3002\u6839\u64da\u5354\u8b70\u689d\u6b3e\uff0cVenatorx \u5c07\u7372\u5f97\u4e00\u7b46\u9810\u4ed8\u7279\u8a31\u6b0a\u8cbb\uff1b\u984d\u5916\u7684\u7814\u767c\u3001\u76e3\u7ba1\u548c\u57fa\u65bc\u92b7\u552e\u984d\u7684\u968e\u6bb5\u6027\u4ed8\u6b3e\uff0c\u4ee5\u53ca\u57fa\u65bc\u51c8\u92b7\u552e\u984d\u7684\u6f5b\u5728\u6b0a\u5229\u91d1\u3002<\/p>\n

Venatorx \u884c\u653f\u7e3d\u88c1\u00a0Christopher J. Burns \u535a\u58eb\u8868\u793a\uff1a\u300c\u900f\u904e\u00a0Menarini \u7684\u5168\u7403\u5546\u696d\u57fa\u790e\u8a2d\u65bd\uff0c\u4ee5\u53ca\u5c07\u6297\u751f\u7d20\u7b49\u50b3\u67d3\u75c5\u7522\u54c1\u5546\u54c1\u5316\u65b9\u9762\u7684\u91cd\u8981\u7d93\u9a57\uff0c\u8a72\u516c\u53f8\u662f\u5c07\u00a0cefepime-taniborbactam \u5f15\u5165\u91cd\u8981\u5730\u57df\u5e02\u5834\u7684\u7406\u60f3\u9078\u64c7\u3002\u300d\u4ed6\u53c8\u8868\u793a\uff1a\u300c\u958b\u767c\u5177\u6709\u5168\u9762\u8010\u85e5\u6027\u8986\u84cb\u7bc4\u570d\u7684\u65b0\u578b\u6297\u751f\u7d20\uff0c\u5c0d\u65bc\u61c9\u5c0d\u5168\u7403\u91cd\u5927\u672a\u6eff\u8db3\u91ab\u7642\u9700\u6c42\u81f3\u95dc\u91cd\u8981\uff0c\u4e26\u53ef\u4ee5\u70ba\u60a3\u8005\u548c\u91ab\u7642\u4fdd\u5065\u63d0\u4f9b\u5e0c\u671b\uff0c\u6709\u6548\u6cbb\u7642\u4e0d\u65b7\u589e\u9577\u7684\u8010\u85e5\u6027\u9769\u862d\u6c0f\u9670\u6027\u83cc\u611f\u67d3\u3002\u300d<\/p>\n

Menarini Group \u884c\u653f\u7e3d\u88c1\u00a0Elcin Barker Ergun \u8868\u793a\uff1a\u300c\u5728\u00a0Menarini\uff0c\u6211\u5011\u76f8\u4fe1\u00a0cefepime-taniborbactam \u7684\u52a0\u5165\u53ef\u4ee5\u64f4\u5927\u6211\u5011\u73fe\u6709\u7684\u00a0AMR \u6297\u611f\u67d3\u85e5\u7269\u7d44\u5408\uff0c\u4e26\u8b93\u6211\u5011\u6709\u6a5f\u6703\u53ef\u4ee5\u9032\u4e00\u6b65\u52a0\u5f37\u5efa\u7acb\u91cd\u8981\u6297\u751f\u7d20\uff0c\u4ee5\u91dd\u5c0d\u7d55\u5927\u591a\u6578\u5177\u6297\u751f\u7d20\u6297\u85e5\u6027\u7684\u91cd\u8981\u75c5\u539f\u9ad4\u3002\u300d\u4ed6\u53c8\u8868\u793a\uff1a\u300c\u85c9\u8457\u501f\u52a9\u6211\u5011\u7684\u5c08\u696d\u77e5\u8b58\u53ca\u00a0Menarini \u5ee3\u5927\u7684\u5546\u696d\u57fa\u790e\u8a2d\u65bd\uff0c\u6211\u5011\u5c07\u80fd\u5728\u53d6\u5f97\u76f8\u95dc\u885b\u751f\u90e8\u9580\u6279\u51c6\u5f8c\uff0c\u5b8c\u5584\u00a0cefepime-taniborbactam \u7684\u5546\u54c1\u5316\u904e\u7a0b\uff0c\u4e26\u78ba\u4fdd\u60a3\u8005\u80fd\u5728\u6211\u5011\u7684\u5168\u7403\u696d\u52d9\u7bc4\u570d\u53d6\u5f97\u9019\u7a2e\u85e5\u7269\u3002\u300d<\/p>\n

Cefepime-Taniborbactam <\/b>\u7c21\u4ecb<\/b><\/p>\n

Cefepime-taniborbactam \u662f\u4e00\u7a2e\u5728\u8a66\u9a57\u968e\u6bb5\u7684\u975c\u8108\u6ce8\u5c04\u00a0(IV) \u03b2-\u5167\u91af\u80fa\u985e\uff0f\u03b2-\u5167\u91af\u80fa\u9176\u985e\u6291\u5236\u5291\u00a0(BL\/BLI) \u6297\u751f\u7d20\u7d44\u5408\uff0c\u5176\u958b\u767c\u76ee\u7684\u662f\u7528\u65bc\u6cbb\u7642\u814e\u76c2\u814e\u708e\u7b49\u8907\u96dc\u6027\u6ccc\u5c3f\u9053\u611f\u67d3\u00a0(cUTI)\uff0c\u4ee5\u53ca\u91ab\u9662\u611f\u67d3\u6027\u7d30\u83cc\u6027\u80ba\u708e\u548c\u547c\u5438\u5668\u76f8\u95dc\u7d30\u83cc\u6027\u80ba\u708e\u00a0(HABP\/VABP)\u3002Cefepime-taniborbactam \u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u5df2\u63d0\u4ea4\u7f8e\u570b\u00a0FDA \u4ee5\u63a5\u53d7\u7528\u65bc\u814e\u76c2\u814e\u708e\u7b49\u00a0cUTI \u7684\u5be9\u67e5\uff0cPDUFA \u65e5\u671f\u70ba\u00a02024 \u5e74\u00a02 \u6708\u00a022 \u65e5\u3002\u00a0<\/p>\n

Cefepime \u662f\u7b2c\u56db\u4ee3\u982d\u5b62\u83cc\u7d20\uff0c\u73fe\u6642\u5ee3\u6cdb\u7528\u65bc\u00a0\u03b2-\u5167\u91af\u80fa\u985e\u00a0(BL) \u6297\u751f\u7d20\uff0c\u5c0d\u654f\u611f\u7684\u9769\u862d\u6c0f\u9670\u6027\u83cc\u548c\u9769\u862d\u6c0f\u967d\u6027\u83cc\u5177\u6709\u8d85\u904e\u4e8c\u5341\u5e74\u7684\u5b89\u5168\u6027\u548c\u81e8\u5e8a\u6548\u7528\u3002Taniborbactam \u662f\u00a0\u03b2-\u5167\u91af\u80fa\u9176\u985e\u6291\u5236\u5291\u00a0(BLI)\uff0c\u8207\u00a0cefepime \u914d\u5408\u4f7f\u7528\uff0c\u76ee\u524d\u6b63\u5728\u7814\u7a76\u7528\u4f5c\u60a3\u6709\u56e0\u5177\u6297\u751f\u7d20\u6297\u85e5\u6027\u7684\u9769\u862d\u6c0f\u9670\u6027\u83cc\u5f15\u8d77\u7684\u7d30\u83cc\u611f\u67d3\u4e4b\u75c5\u4eba\u7684\u5177\u6f5b\u529b\u6cbb\u7642\u9078\u9805\uff0c\u7279\u5225\u662f\u91dd\u5c0d\u8d85\u5ee3\u6548\u6027\u7684\u00a0\u03b2-\u5167\u91af\u80fa\u9176\u00a0(ESBL) \u8868\u73fe\u7684\u8178\u687f\u83cc\u3001\u6297\u78b3\u9752\u9ef4\u70ef\u8178\u687f\u83cc\u00a0(CRE)\uff0c\u4ee5\u53ca\u591a\u91cd\u8010\u85e5\u6027\u00a0(MDR) \u7da0\u81bf\u687f\u83cc\u00a0(MDR-PA)\uff0c\u5176\u4e2d\u5305\u62ec\u6297\u78b3\u9752\u9ef4\u70ef\u7da0\u81bf\u687f\u83cc\u00a0(CRPA)\u3002<\/p>\n

Cefepime-taniborbactam \u5df2\u7372\u7f8e\u570b\u98df\u7269\u53ca\u85e5\u7269\u76e3\u7763\u7ba1\u7406\u5c40\u00a0(FDA) \u7684\u5408\u683c\u611f\u67d3\u6027\u75be\u75c5\u7522\u54c1\u8cc7\u683c\u00a0(QIDP) \u53ca\u5feb\u901f\u5be9\u67e5\u8a8d\u5b9a\uff0c\u53ef\u7528\u65bc\u6cbb\u7642\u00a0cUTI \u548c\u00a0HABP\/VABP\u3002<\/p>\n

\u8cc7\u52a9\u5408\u5925\u6a5f\u69cb\u548c\u5408\u4f5c\u5925\u4f34<\/b><\/p>\n

Cefepime-taniborbactam \u7684\u958b\u767c\u59cb\u65bc\u7f8e\u570b\u570b\u5bb6\u904e\u654f\u548c\u50b3\u67d3\u75c5\u7814\u7a76\u6240\u3001\u7f8e\u570b\u570b\u5bb6\u885b\u751f\u9662\u3001\u7f8e\u570b\u885b\u751f\u53ca\u516c\u5171\u670d\u52d9\u90e8\u7684\u806f\u90a6\u8cc7\u91d1\uff0c\u5408\u540c\u7de8\u865f\u70ba\u00a0HHSN272201300019C\uff1bWellcome Trust \u734e\u91d1\u7de8\u865f\u70ba\u00a0360G-Wellcome-101999\/Z\/13\/Z \u7684\u8cc7\u91d1\uff1b\u4ee5\u53ca\u751f\u7269\u91ab\u5b78\u9032\u968e\u7814\u7a76\u53ca\u958b\u767c\u59d4\u54e1\u6703\u00a0(BARDA) \u548c\u7f8e\u570b\u885b\u751f\u53ca\u516c\u5171\u670d\u52d9\u90e8\u6230\u7565\u6e96\u5099\u548c\u61c9\u5c0d\u7ba1\u7406\u7f72\u5f8c\u7e8c\u63d0\u4f9b\u7684\u806f\u90a6\u8cc7\u91d1\uff0c\u5408\u540c\u7de8\u865f\u70ba\u00a0HHSO100201900007C \u548c\u00a075A50122C00080\u3002<\/p>\n

\u5728\u00a02018 \u5e74\u00a09 \u6708\uff0cVenatorx \u8207\u00a0Everest Medicines \u9054\u6210\u7368\u5bb6\u8a31\u53ef\u5354\u8b70<\/a>\uff0c\u4ee5\u652f\u6301\u5728\u4e2d\u83ef\u4eba\u6c11\u5171\u548c\u570b\u3001\u6fb3\u9580\u3001\u9999\u6e2f\u3001\u53f0\u7063\u3001\u5357\u97d3\u548c\u6771\u5357\u4e9e\u90e8\u5206\u570b\u5bb6\uff08\u5408\u7a31\u70ba\u300c\u5730\u5340\u300d\uff09\u9032\u884c\u00a0cefepime-taniborbactam \u7684\u958b\u767c\u3001\u8a3b\u518a\u548c\u5546\u54c1\u5316\u3002<\/p>\n

\u5728\u00a02020 \u5e74\u00a04 \u6708\uff0cVenatorx \u8207\u00a0GARDP \u5ba3\u4f48\u5408\u4f5c<\/a>\uff0c\u52a0\u5feb\u6210\u4eba\u53ca\u5152\u7ae5\u7528\u00a0cefepime-taniborbactam \u7684\u958b\u767c\u548c\u63d0\u4f9b\u3002Venatorx \u5411\u00a0GARDP \u6388\u4e88\u5728\u00a0cefepime-taniborbactam \u53d6\u5f97\u81e8\u5e8a\u4f7f\u7528\u6279\u51c6\u5f8c\uff0c\u65bc\u7279\u5b9a\u4f4e\u6536\u5165\u548c\u4e2d\u4f4e\u6536\u5165\u570b\u5bb6\u7368\u5bb6\u5206\u914d\u53ca\u5206\u92b7\u9019\u7a2e\u85e5\u7269\u7684\u6b0a\u5229\u3002<\/p>\n

\u5728\u00a02023 \u5e74\u00a011 \u6708\uff0cVenatorx \u8207\u00a0Melinta Therapeutics \u9054\u6210\u7368\u5bb6\u8a31\u53ef\u5354\u8b70\uff0c\u5728\u7f8e\u570b\u5c07\u00a0cefepime-taniborbactam \u5546\u54c1\u5316\u3002<\/p>\n

Venatorx Pharmaceuticals, Inc. <\/b>\u7c21\u4ecb<\/b><\/p>\n

Venatorx \u662f\u4e00\u5bb6\u79c1\u71df\u3001\u5546\u696d\u5316\u524d\u671f\u7684\u88fd\u85e5\u516c\u53f8\uff0c\u5c08\u6ce8\u6539\u5584\u60a3\u6709\u96e3\u4ee5\u6cbb\u7642\u7684\u6297\u85e5\u6027\u9769\u862d\u6c0f\u9670\u6027\u83cc\u611f\u67d3\u53ca\u75c5\u6bd2\u611f\u67d3\u60a3\u8005\u7684\u5065\u5eb7\u72c0\u6cc1\u3002Venatorx \u7684\u4e3b\u8981\u9805\u76ee\u00a0cefepime-taniborbactam \u662f\u4e00\u7a2e\u5728\u8a66\u9a57\u968e\u6bb5\u7684\u6297\u751f\u7d20\uff0c\u5176\u5df2\u5728\u6210\u4eba\u8eab\u4e0a\u5b8c\u6210\u91dd\u5c0d\u814e\u76c2\u814e\u708e\u7b49\u8907\u96dc\u6027\u6ccc\u5c3f\u9053\u611f\u67d3\u00a0(cUTI) \u7684\u00a03 \u671f\u81e8\u5e8a\u7814\u7a76\u00a0(NCT03840148<\/a>)\uff0c\u5176\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u6b63\u5728\u63a5\u53d7\u00a0FDA \u5be9\u67e5\uff0cPDUFA \u65e5\u671f\u70ba\u00a02024 \u5e74\u00a02 \u6708\u00a022 \u65e5\u3002\u5728\u00a02022 \u5e74\u00a010 \u6708\uff0cBARDA \u5411\u00a0Venatorx \u6388\u4e88\u751f\u7269\u9632\u79a6\u8a08\u5283\uff08Project Bioshield\uff09\u5408\u540c\uff0c\u91d1\u984d\u9ad8\u9054\u00a03.18 \u5104\u7f8e\u5143\uff0c\u4ee5\u958b\u767c\u53ca\u63a1\u8cfc\u00a0cefepime-taniborbactam \u4f86\u7528\u65bc\u6cbb\u7642\u6297\u85e5\u6027\u9769\u862d\u6c0f\u9670\u6027\u83cc\u611f\u67d3\uff0c\u5305\u62ec\u985e\u9f3b\u75bd\u3002\u4f5c\u70ba\u5176\u5ee3\u5927\u8a08\u5283\u7684\u4e00\u90e8\u5206\uff0cVenatorx \u4ea6\u5728\u958b\u767c\u4e00\u7a2e\u53e3\u670d\u7684\u00a0BL\/BLI \u6297\u83cc\u85e5\u7269\uff0c\u540d\u70ba\u00a0ceftibuten-ledaborbactam etzadroxil\uff0c\u6839\u64da\u8fd1\u671f\u5ba3\u4f48\u7684\u00a0BARDA \u65b0\u5408\u540c\uff0c\u9019\u7a2e\u85e5\u7269\u5c07\u6703\u76f4\u63a5\u9032\u5165\u5168\u7403\u00a03 \u671f\u00a0cUTI \u81e8\u5e8a\u8a66\u9a57\u3002\u5982\u9700\u66f4\u591a\u95dc\u65bc\u00a0Venatorx \u53ca\u5176\u6297\u611f\u67d3\u85e5\u7269\u7d44\u5408\u7684\u8cc7\u8a0a\uff0c\u8acb\u700f\u89bd\u00a0www.venatorx.com<\/a>\u3002<\/p>\n

Menarini Group <\/b>\u7c21\u4ecb<\/b><\/p>\n

Menarini Group \u662f\u4e00\u5bb6\u9818\u5148\u7684\u570b\u969b\u91ab\u85e5\u548c\u8a3a\u65b7\u516c\u53f8\uff0c\u5e74\u71df\u696d\u984d\u8d85\u904e\u00a044 \u5104\u7f8e\u5143\uff0c\u64c1\u6709\u8d85\u904e\u00a017,000 \u540d\u54e1\u5de5\u3002Menarini \u5c08\u6ce8\u65bc\u6cbb\u7642\u9700\u6c42\u9ad8\u5ea6\u672a\u6eff\u8db3\u7684\u9818\u57df\uff0c\u5176\u7522\u54c1\u6db5\u84cb\u5fc3\u81df\u75c5\u5b78\u3001\u816b\u7624\u5b78\u3001\u547c\u5438\u75c5\u5b78\u3001\u80c3\u8178\u75c5\u5b78\u3001\u50b3\u67d3\u75c5\u5b78\u3001\u7cd6\u5c3f\u75c5\u5b78\u3001\u708e\u75c7\u548c\u93ae\u75db\u7b49\u9818\u57df\u3002Menarini \u64c1\u6709\u00a018 \u500b\u751f\u7522\u57fa\u5730\u548c\u00a09 \u500b\u7814\u767c\u4e2d\u5fc3\uff0c\u7522\u54c1\u92b7\u5f80\u5168\u7403\u00a0140 \u500b\u570b\u5bb6\/\u5730\u5340\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u76f8\u95dc\u8cc7\u8a0a\uff0c\u8acb\u700f\u89bd\u00a0www.menarini.com<\/a>\u3002<\/p>\n

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\u4eca\u65e5\u5ba3\u4f48\u4ed6\u5011\u5df2\u9054\u6210\u5354\u8b70\uff0cMenarini \u5c07\u6703\u7372\u5f97\u7368\u5bb6\u6b0a\u5229\uff0c\u53ef\u65bc\u6b50\u6d32\u3001\u62c9\u4e01\u7f8e\u6d32\u3001\u4e2d\u6771\u3001\u571f\u8033\u5176\u3001\u5317\u975e\u548c\u7368\u7acb\u570b\u5bb6\u806f\u5408\u9ad4 (CIS) \u7684 96 \u500b\u570b\u5bb6\uff0c\u5728\u53d6\u5f97\u76f8\u95dc\u885b\u751f\u90e8\u9580\u7684\u6279\u51c6\u5f8c\uff0c\u5c07 cefepime-taniborbactam \u5546\u54c1\u5316\u3002\u6839\u64da\u5354\u8b70\u689d\u6b3e\uff0cVenatorx \u5c07\u7372\u5f97\u4e00\u7b46\u9810\u4ed8\u7279\u8a31\u6b0a\u8cbb\uff1b\u984d\u5916\u7684\u7814\u767c\u3001\u76e3\u7ba1\u548c\u57fa\u65bc\u92b7\u552e\u984d\u7684\u968e\u6bb5\u6027\u4ed8\u6b3e\uff0c\u4ee5\u53ca\u57fa\u65bc\u51c8\u92b7\u552e\u984d\u7684\u6f5b\u5728\u6b0a\u5229\u91d1\u3002 Venatorx \u884c\u653f\u7e3d\u88c1\u00a0Christopher J. Burns \u535a\u58eb\u8868\u793a\uff1a\u300c\u900f\u904e\u00a0Menarini \u7684\u5168\u7403\u5546\u696d\u57fa\u790e\u8a2d\u65bd\uff0c\u4ee5\u53ca\u5c07\u6297\u751f\u7d20\u7b49\u50b3\u67d3\u75c5\u7522\u54c1\u5546\u54c1\u5316\u65b9\u9762\u7684\u91cd\u8981\u7d93\u9a57\uff0c\u8a72\u516c\u53f8\u662f\u5c07\u00a0cefepime-taniborbactam \u5f15\u5165\u91cd\u8981\u5730\u57df\u5e02\u5834\u7684\u7406\u60f3\u9078\u64c7\u3002\u300d\u4ed6\u53c8\u8868\u793a\uff1a\u300c\u958b\u767c\u5177\u6709\u5168\u9762\u8010\u85e5\u6027\u8986\u84cb\u7bc4\u570d\u7684\u65b0\u578b\u6297\u751f\u7d20\uff0c\u5c0d\u65bc\u61c9\u5c0d\u5168\u7403\u91cd\u5927\u672a\u6eff\u8db3\u91ab\u7642\u9700\u6c42\u81f3\u95dc\u91cd\u8981\uff0c\u4e26\u53ef\u4ee5\u70ba\u60a3\u8005\u548c\u91ab\u7642\u4fdd\u5065\u63d0\u4f9b\u5e0c\u671b\uff0c\u6709\u6548\u6cbb\u7642\u4e0d\u65b7\u589e\u9577\u7684\u8010\u85e5\u6027\u9769\u862d\u6c0f\u9670\u6027\u83cc\u611f\u67d3\u3002\u300d Menarini Group \u884c\u653f\u7e3d\u88c1\u00a0Elcin Barker Ergun \u8868\u793a\uff1a\u300c\u5728\u00a0Menarini\uff0c\u6211\u5011\u76f8\u4fe1\u00a0cefepime-taniborbactam \u7684\u52a0\u5165\u53ef\u4ee5\u64f4\u5927\u6211\u5011\u73fe\u6709\u7684\u00a0AMR \u6297\u611f\u67d3\u85e5\u7269\u7d44\u5408\uff0c\u4e26\u8b93\u6211\u5011\u6709\u6a5f\u6703\u53ef\u4ee5\u9032\u4e00\u6b65\u52a0\u5f37\u5efa\u7acb\u91cd\u8981\u6297\u751f\u7d20\uff0c\u4ee5\u91dd\u5c0d\u7d55\u5927\u591a\u6578\u5177\u6297\u751f\u7d20\u6297\u85e5\u6027\u7684\u91cd\u8981\u75c5\u539f\u9ad4\u3002\u300d\u4ed6\u53c8\u8868\u793a\uff1a\u300c\u85c9\u8457\u501f\u52a9\u6211\u5011\u7684\u5c08\u696d\u77e5\u8b58\u53ca\u00a0Menarini \u5ee3\u5927\u7684\u5546\u696d\u57fa\u790e\u8a2d\u65bd\uff0c\u6211\u5011\u5c07\u80fd\u5728\u53d6\u5f97\u76f8\u95dc\u885b\u751f\u90e8\u9580\u6279\u51c6\u5f8c\uff0c\u5b8c\u5584\u00a0cefepime-taniborbactam \u7684\u5546\u54c1\u5316\u904e\u7a0b\uff0c\u4e26\u78ba\u4fdd\u60a3\u8005\u80fd\u5728\u6211\u5011\u7684\u5168\u7403\u696d\u52d9\u7bc4\u570d\u53d6\u5f97\u9019\u7a2e\u85e5\u7269\u3002\u300d Cefepime-Taniborbactam \u7c21\u4ecb Cefepime-taniborbactam \u662f\u4e00\u7a2e\u5728\u8a66\u9a57\u968e\u6bb5\u7684\u975c\u8108\u6ce8\u5c04\u00a0(IV) \u03b2-\u5167\u91af\u80fa\u985e\uff0f\u03b2-\u5167\u91af\u80fa\u9176\u985e\u6291\u5236\u5291\u00a0(BL\/BLI) \u6297\u751f\u7d20\u7d44\u5408\uff0c\u5176\u958b\u767c\u76ee\u7684\u662f\u7528\u65bc\u6cbb\u7642\u814e\u76c2\u814e\u708e\u7b49\u8907\u96dc\u6027\u6ccc\u5c3f\u9053\u611f\u67d3\u00a0(cUTI)\uff0c\u4ee5\u53ca\u91ab\u9662\u611f\u67d3\u6027\u7d30\u83cc\u6027\u80ba\u708e\u548c\u547c\u5438\u5668\u76f8\u95dc\u7d30\u83cc\u6027\u80ba\u708e\u00a0(HABP\/VABP)\u3002Cefepime-taniborbactam \u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u5df2\u63d0\u4ea4\u7f8e\u570b\u00a0FDA \u4ee5\u63a5\u53d7\u7528\u65bc\u814e\u76c2\u814e\u708e\u7b49\u00a0cUTI 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