{"id":169526,"date":"2023-08-10T15:36:00","date_gmt":"2023-08-10T07:36:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=169526"},"modified":"2023-08-10T15:36:00","modified_gmt":"2023-08-10T07:36:00","slug":"%e8%97%b9%e7%9d%a6%e9%86%ab%e7%99%82%e5%ae%a3%e5%b8%83%e5%90%88%e4%bd%9c%e4%bc%99%e4%bc%b4vistagen%e7%9a%84fasedienol%ef%bc%88ph94b%ef%bc%89%e9%bc%bb%e5%99%b4%e5%8a%91%e5%9c%a8%e6%b2%bb%e7%99%82","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=169526","title":{"rendered":"\u85f9\u7766\u91ab\u7642\u5ba3\u5e03\u5408\u4f5c\u4f19\u4f34Vistagen\u7684Fasedienol\uff08PH94B\uff09\u9f3b\u5674\u5291\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u76843\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u4e2d\u53d6\u5f97\u7a4d\u6975\u7d50\u679c"},"content":{"rendered":"<div>\n<ul type=\"disc\">\n<li><i>15<\/i><i>\u5e74\u4f86\u793e\u4ea4\u7126\u616e\u969c\u7919\u7642\u6cd5\u5728\u7f8e\u570b\u7684\u9996\u500b\u967d\u6027\u7d50\u679c3<\/i><i>\u671f\u7814\u7a76<\/i><\/li>\n<li><i>\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u4e2d\uff0cFasedienol<\/i><i>\u7d44\u60a3\u8005\u5831\u544a\u7684\u4e3b\u89c0\u75db\u82e6\u611f\u89ba\u55ae\u4f4d\u91cf\u8868\uff08SUDS<\/i><i>\uff09\u8a55\u5206\u8b8a\u5316\u76f8\u6bd4\u5b89\u6170\u5291\u7d44\u986f\u8457\u6539\u5584\uff08\u4e3b\u8981\u7d42\u9ede\uff0cp=0.015<\/i><i>\uff09<\/i><\/li>\n<li><i>\u8a66\u9a57\u4e5f\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0c\u901a\u904e\u81e8\u5e8a\u6574\u9ad4\u5370\u8c61\u6539\u5584\uff08CGI-I<\/i><i>\uff09\u91cf\u8868\u8a55\u4f30\uff0cFasedienol<\/i><i>\u7d44\u60a3\u8005\u7684\u61c9\u7b54\u7387\u4e5f\u986f\u8457\u9ad8\u65bc\u5b89\u6170\u5291\u7d44\uff08\u6b21\u8981\u7d42\u9ede\uff0cp=0.033<\/i><i>\uff09\u3002<\/i><\/li>\n<li><i>Fasedienol<\/i><i>\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002<\/i><\/li>\n<li><i>\u5168\u7403\u67091.88<\/i><i>\u5104\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\uff0c\u5176\u4e2d\u7f8e\u570b\u8d85\u904e2500<\/i><i>\u842c\u60a3\u8005\uff0c\u4e2d\u570b\u81f3\u5c11\u67091130<\/i><i>\u842c\u60a3\u8005<sup>1,2,3<\/sup>\u00a0<\/i><\/li>\n<\/ul>\n<p>\u4e0a\u6d772023\u5e748\u670810\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u85f9\u7766\u91ab\u7642\uff08AffaMed Therapeutics\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u5408\u4f5c\u4f19\u4f34 Vistagen Therapeutics\uff08\u300cVistagen\u300d &#8211; \u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aVTGN\uff09\u4e00\u5bb6\u65e8\u5728\u6539\u8b8a\u7126\u616e\u3001\u6291\u90c1\u548c\u5176\u4ed6\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71 \uff08CNS\uff09 \u75be\u75c5\u60a3\u8005\u6cbb\u7642\u683c\u5c40\u7684\u81e8\u5e8a\u968e\u6bb5\u751f\u7269\u5236\u85e5\u516c\u53f8\uff0c \u5176PALISADE-2 \u8a55\u4f30Fasedienol \uff08PH94B\uff09 \u9f3b\u5674\u5291\u5728\u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u7642\u6548\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u76843 \u671f\u81e8\u5e8a\u8a66\u9a57\u53d6\u5f97\u4e86\u967d\u6027\u7d50\u679c\u3002\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0cFasedienol\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u5e73\u5747SUDS\u8a55\u5206\u8b8a\u5316\u6709\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff08p = 0.015\uff09\u3002\u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e4b\u9593\u6709\u986f\u8457\u5dee\u7570\uff08p = 0.033\uff09\u3002Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002<\/p>\n<p>2020\u5e746\u6708\uff0c\u85f9\u7766\u91ab\u7642\u8207VistaGen\u7c3d\u8a02\u4e86\u6230\u7565\u8a31\u53ef\u548c\u5408\u4f5c\u5354\u8b70\uff0c\u7372\u5f97\u4e86PH94B\u5728\u4e2d\u570b\u3001\u97d3\u570b\u548c\u6771\u5357\u4e9e\u7684\u81e8\u5e8a\u958b\u767c\u548c\u5546\u696d\u5316\u6b0a\u76ca\u3002<\/p>\n<p>\u300c\u6211\u5011\u5f88\u9ad8\u82083\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u7684\u7d50\u679c\u9032\u4e00\u6b65\u8b49\u5be6\u4e862\u671f\u7814\u7a76\u4e2d\u6240\u770b\u5230\u7684\u60c5\u6cc1\uff0c\u4e26\u986f\u793a\u4e86Fasedienol\u7684\u5de8\u5927\u6f5b\u529b\uff0c\u5176\u65b0\u7a4e\u800c\u7368\u7279\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u53ef\u4ee5\u6539\u8b8a\u7f8e\u570b\u8d85\u904e2500\u842c\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u53ca\u5168\u7403\u6578\u767e\u842c\u60a3\u8005\u7684\u6cbb\u7642\u53ef\u80fd\u6027\u300d\uff0cVistagen\u9996\u5e2d\u57f7\u884c\u5b98Shawn Singh\u8aaa\u3002\u300c\u4f5c\u70ba\u4e00\u985e\u65b0\u578b\u85e5\u7269\uff0c\u6211\u5011\u7684\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\u7ba1\u7dda\u5177\u6709\u6539\u8b8a\u773e\u591a\u6cbb\u7642\u9818\u57df\u683c\u5c40\u7684\u6f5b\u529b\u3002\u6b63\u59823\u671f\u8a66\u9a57\u6240\u8b49\u660e\u7684\u90a3\u6a23\uff0cFasedienol\u8655\u65bc\u8a72\u985e\u85e5\u7269\u7684\u9818\u5148\u5730\u4f4d\uff0c\u5176\u6f5b\u529b\u70ba\u6210\u70ba20\u591a\u5e74\u4f86\u9996\u500b\u91dd\u5c0d\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7684\u5168\u65b0\u85e5\u7269\u985e\u5225\u5960\u5b9a\u4e86\u57fa\u790e\u3002\u300d<\/p>\n<p>\u85f9\u7766\u91ab\u7642\u9996\u5e2d\u57f7\u884c\u5b98\u8d99\u5927\u582f\u535a\u58eb\u8a55\u8ad6\u9053\uff1a\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u770b\u5230PALISADE-2\u8a66\u9a57\u7684\u7d50\u679c\u8b49\u660e\u4e86Fasedienol\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u65b9\u9762\u7684\u6f5b\u529b\uff0c\u4e26\u671f\u5f85\u8207Vistagen\u5408\u4f5c\uff0c\u70ba\u4e2d\u570b\uff0c\u97d3\u570b\u548c\u6771\u5357\u4e9e\u65e5\u76ca\u589e\u9577\u7684\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u300d<\/p>\n<p><b>\u4e3b\u8981\u7642\u6548\u7d42\u9ede<\/b><\/p>\n<p>PALISADE-2\u8a66\u9a57\uff08n=141\uff09\u9054\u5230\u4e86\u4e3b\u8981\u7642\u6548\u7d42\u9ede\uff0c\u5373\u00a0Fasedienol\uff08n = 70\uff09\u6cbb\u7642\u7d44\u8207\u5b89\u6170\u5291\u7d44\uff08n = 71\uff09\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09\u7684\u5e73\u5747SUDS\u8a55\u5206\u76f8\u8f03\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u8b8a\u5316\u7684\u5dee\u7570\u3002\u8207\u5b89\u6170\u5291\u7d44\uff08LS\u5e73\u5747\u503c= -8.0\uff09\u76f8\u6bd4\uff0cFasedienol\u6cbb\u7642\u7d44SUDS\u5e73\u5747\u8a55\u5206\u8b8a\u5316\uff08\u6700\u5c0f\u4e8c\u4e58\uff08LS\uff09\u5e73\u5747\u503c= -13.8\uff09\u6709\u986f\u8457\u5dee\u7570\uff0c\u7d44\u9593\u5dee\u7570\u70ba-5.8\uff08p = 0.015\uff09\u3002<\/p>\n<p><b>\u6b21\u8981\u7642\u6548\u7d42\u9ede<\/b><\/p>\n<p>\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e0a\u6709\u986f\u8457\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u88ab\u8a55\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba37.7%\uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba21.4%\uff08n = 71\uff09\uff08p = 0.033\uff09\u3002<\/p>\n<p><b>\u63a2\u7d22\u6027\u7642\u6548\u7d42\u9ede<\/b><\/p>\n<p>\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e00\u500b\u91cd\u8981\u7684\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u901a\u904e\u60a3\u8005\u5c0d\u75c5\u60c5\u8b8a\u5316\u7684\u7e3d\u9ad4\u5370\u8c61\uff08PGI-C\uff09\u91cf\u8868\u8861\u91cf\u7684Fasedienol\u548c\u5b89\u6170\u5291\u4e4b\u9593\u61c9\u7b54\u7387\u7684\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u81ea\u6211\u8a55\u50f9\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba40.6% \uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n = 71\uff09\uff08p = 0.003\uff09\u3002<\/p>\n<p>\u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u5169\u7d44\u9593\u5f9e\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u5230\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09SUDS\u8a55\u5206\u6539\u5584\u81f3\u5c1120\u5206\uff08\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u6539\u5584\uff09\u7684\u60a3\u8005\u6bd4\u4f8b\uff0cFasedieno\u7d44\u70ba35.7%\uff08n=70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n=71\uff09\uff0c\u5169\u7d44\u4e4b\u9593\u6709\u986f\u8457\u7d71\u8a08\u5b78\u5dee\u7570\uff08p=0.020\uff09\u3002<\/p>\n<p><b>\u5b89\u5168\u6027<\/b><\/p>\n<p>\u7814\u7a76\u986f\u793aFasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u5831\u544a\u91cd\u5ea6\u6216\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08AEs\uff09\u3002\u5728\u6574\u500b\u7814\u7a76\u4e2d\uff0c\u6240\u6709\u6cbb\u7642\u671f\u9593\u51fa\u73fe\u7684\u4e0d\u826f\u4e8b\u4ef6\u5747\u70ba\u8f15\u5ea6\u6216\u4e2d\u5ea6\u3002\u5728Fasedienol\u6cbb\u7642\u7d44\u4e2d\uff0c\u672a\u5831\u544a\u767c\u751f\u7387\u8d85\u904e2%\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002<\/p>\n<p><b>\u95dc\u65bc 3 <\/b><b>\u671f PALISADE-2 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3 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border=\"1\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">1. National Health and Wellness Survey (NHWS), 2021.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">2. Stein, D.J., Lim, C.C.W., Roest, A.M. et al. The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative. BMC Med 15, 143 (2017).<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">3. Frost &amp; Sullivan. January 2022. Global Market Study of CNS and Opthalmic Treatment Market, 2022. Shanghai, China.<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>\u00a0<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>15\u5e74\u4f86\u793e\u4ea4\u7126\u616e\u969c\u7919\u7642\u6cd5\u5728\u7f8e\u570b&#8230;<\/p>\n","protected":false},"author":16,"featured_media":199219,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-169526","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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\u8a66\u9a57\u4e5f\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0c\u901a\u904e\u81e8\u5e8a\u6574\u9ad4\u5370\u8c61\u6539\u5584\uff08CGI-I\uff09\u91cf\u8868\u8a55\u4f30\uff0cFasedienol\u7d44\u60a3\u8005\u7684\u61c9\u7b54\u7387\u4e5f\u986f\u8457\u9ad8\u65bc\u5b89\u6170\u5291\u7d44\uff08\u6b21\u8981\u7d42\u9ede\uff0cp=0.033\uff09\u3002  Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002  \u5168\u7403\u67091.88\u5104\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\uff0c\u5176\u4e2d\u7f8e\u570b\u8d85\u904e2500\u842c\u60a3\u8005\uff0c\u4e2d\u570b\u81f3\u5c11\u67091130\u842c\u60a3\u80051,2,3\u00a0 \u4e0a\u6d772023\u5e748\u670810\u65e5 \/\u7f8e\u901a\u793e\/ -- \u85f9\u7766\u91ab\u7642\uff08AffaMed Therapeutics\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u5408\u4f5c\u4f19\u4f34 Vistagen Therapeutics\uff08\u300cVistagen\u300d - \u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aVTGN\uff09\u4e00\u5bb6\u65e8\u5728\u6539\u8b8a\u7126\u616e\u3001\u6291\u90c1\u548c\u5176\u4ed6\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71 \uff08CNS\uff09 \u75be\u75c5\u60a3\u8005\u6cbb\u7642\u683c\u5c40\u7684\u81e8\u5e8a\u968e\u6bb5\u751f\u7269\u5236\u85e5\u516c\u53f8\uff0c \u5176PALISADE-2 \u8a55\u4f30Fasedienol \uff08PH94B\uff09 \u9f3b\u5674\u5291\u5728\u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u7642\u6548\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u76843 \u671f\u81e8\u5e8a\u8a66\u9a57\u53d6\u5f97\u4e86\u967d\u6027\u7d50\u679c\u3002\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0cFasedienol\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u5e73\u5747SUDS\u8a55\u5206\u8b8a\u5316\u6709\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff08p = 0.015\uff09\u3002\u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e4b\u9593\u6709\u986f\u8457\u5dee\u7570\uff08p = 0.033\uff09\u3002Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002 2020\u5e746\u6708\uff0c\u85f9\u7766\u91ab\u7642\u8207VistaGen\u7c3d\u8a02\u4e86\u6230\u7565\u8a31\u53ef\u548c\u5408\u4f5c\u5354\u8b70\uff0c\u7372\u5f97\u4e86PH94B\u5728\u4e2d\u570b\u3001\u97d3\u570b\u548c\u6771\u5357\u4e9e\u7684\u81e8\u5e8a\u958b\u767c\u548c\u5546\u696d\u5316\u6b0a\u76ca\u3002 \u300c\u6211\u5011\u5f88\u9ad8\u82083\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u7684\u7d50\u679c\u9032\u4e00\u6b65\u8b49\u5be6\u4e862\u671f\u7814\u7a76\u4e2d\u6240\u770b\u5230\u7684\u60c5\u6cc1\uff0c\u4e26\u986f\u793a\u4e86Fasedienol\u7684\u5de8\u5927\u6f5b\u529b\uff0c\u5176\u65b0\u7a4e\u800c\u7368\u7279\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u53ef\u4ee5\u6539\u8b8a\u7f8e\u570b\u8d85\u904e2500\u842c\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u53ca\u5168\u7403\u6578\u767e\u842c\u60a3\u8005\u7684\u6cbb\u7642\u53ef\u80fd\u6027\u300d\uff0cVistagen\u9996\u5e2d\u57f7\u884c\u5b98Shawn Singh\u8aaa\u3002\u300c\u4f5c\u70ba\u4e00\u985e\u65b0\u578b\u85e5\u7269\uff0c\u6211\u5011\u7684\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\u7ba1\u7dda\u5177\u6709\u6539\u8b8a\u773e\u591a\u6cbb\u7642\u9818\u57df\u683c\u5c40\u7684\u6f5b\u529b\u3002\u6b63\u59823\u671f\u8a66\u9a57\u6240\u8b49\u660e\u7684\u90a3\u6a23\uff0cFasedienol\u8655\u65bc\u8a72\u985e\u85e5\u7269\u7684\u9818\u5148\u5730\u4f4d\uff0c\u5176\u6f5b\u529b\u70ba\u6210\u70ba20\u591a\u5e74\u4f86\u9996\u500b\u91dd\u5c0d\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7684\u5168\u65b0\u85e5\u7269\u985e\u5225\u5960\u5b9a\u4e86\u57fa\u790e\u3002\u300d \u85f9\u7766\u91ab\u7642\u9996\u5e2d\u57f7\u884c\u5b98\u8d99\u5927\u582f\u535a\u58eb\u8a55\u8ad6\u9053\uff1a\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u770b\u5230PALISADE-2\u8a66\u9a57\u7684\u7d50\u679c\u8b49\u660e\u4e86Fasedienol\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u65b9\u9762\u7684\u6f5b\u529b\uff0c\u4e26\u671f\u5f85\u8207Vistagen\u5408\u4f5c\uff0c\u70ba\u4e2d\u570b\uff0c\u97d3\u570b\u548c\u6771\u5357\u4e9e\u65e5\u76ca\u589e\u9577\u7684\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u300d \u4e3b\u8981\u7642\u6548\u7d42\u9ede PALISADE-2\u8a66\u9a57\uff08n=141\uff09\u9054\u5230\u4e86\u4e3b\u8981\u7642\u6548\u7d42\u9ede\uff0c\u5373\u00a0Fasedienol\uff08n = 70\uff09\u6cbb\u7642\u7d44\u8207\u5b89\u6170\u5291\u7d44\uff08n = 71\uff09\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09\u7684\u5e73\u5747SUDS\u8a55\u5206\u76f8\u8f03\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u8b8a\u5316\u7684\u5dee\u7570\u3002\u8207\u5b89\u6170\u5291\u7d44\uff08LS\u5e73\u5747\u503c= -8.0\uff09\u76f8\u6bd4\uff0cFasedienol\u6cbb\u7642\u7d44SUDS\u5e73\u5747\u8a55\u5206\u8b8a\u5316\uff08\u6700\u5c0f\u4e8c\u4e58\uff08LS\uff09\u5e73\u5747\u503c= -13.8\uff09\u6709\u986f\u8457\u5dee\u7570\uff0c\u7d44\u9593\u5dee\u7570\u70ba-5.8\uff08p = 0.015\uff09\u3002 \u6b21\u8981\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e0a\u6709\u986f\u8457\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u88ab\u8a55\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba37.7%\uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba21.4%\uff08n = 71\uff09\uff08p = 0.033\uff09\u3002 \u63a2\u7d22\u6027\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e00\u500b\u91cd\u8981\u7684\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u901a\u904e\u60a3\u8005\u5c0d\u75c5\u60c5\u8b8a\u5316\u7684\u7e3d\u9ad4\u5370\u8c61\uff08PGI-C\uff09\u91cf\u8868\u8861\u91cf\u7684Fasedienol\u548c\u5b89\u6170\u5291\u4e4b\u9593\u61c9\u7b54\u7387\u7684\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u81ea\u6211\u8a55\u50f9\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba40.6% \uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n = 71\uff09\uff08p = 0.003\uff09\u3002 \u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u5169\u7d44\u9593\u5f9e\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u5230\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09SUDS\u8a55\u5206\u6539\u5584\u81f3\u5c1120\u5206\uff08\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u6539\u5584\uff09\u7684\u60a3\u8005\u6bd4\u4f8b\uff0cFasedieno\u7d44\u70ba35.7%\uff08n=70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n=71\uff09\uff0c\u5169\u7d44\u4e4b\u9593\u6709\u986f\u8457\u7d71\u8a08\u5b78\u5dee\u7570\uff08p=0.020\uff09\u3002 \u5b89\u5168\u6027 \u7814\u7a76\u986f\u793aFasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u5831\u544a\u91cd\u5ea6\u6216\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08AEs\uff09\u3002\u5728\u6574\u500b\u7814\u7a76\u4e2d\uff0c\u6240\u6709\u6cbb\u7642\u671f\u9593\u51fa\u73fe\u7684\u4e0d\u826f\u4e8b\u4ef6\u5747\u70ba\u8f15\u5ea6\u6216\u4e2d\u5ea6\u3002\u5728Fasedienol\u6cbb\u7642\u7d44\u4e2d\uff0c\u672a\u5831\u544a\u767c\u751f\u7387\u8d85\u904e2%\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002 \u95dc\u65bc 3 \u671f PALISADE-2 \u8a66\u9a57 PALISADE-2\u662f\u4e00\u9805\u5728\u6210\u5e74\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u4e2d\u958b\u5c55\u7684\u591a\u4e2d\u5fc3\uff0c\u96a8\u6a5f\uff0c\u96d9\u76f2\uff0c\u5b89\u6170\u5291\u5c0d\u7167\u76843\u671f\u81e8\u5e8a\u7814\u7a76\u3002\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30Fasedienol\u6025\u6027\u4f7f\u7528\u5728\u6a21\u64ec\u5f15\u767c\u7126\u616e\u7684\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u7de9\u89e3\u6210\u5e74\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7126\u616e\u75c7\u72c0\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u4f7f\u7528\u60a3\u8005\u5831\u544a\u7684SUDS\u8a55\u5206\u9032\u884c\u8a55\u4f30\u3002 \u5165\u7d44\u7684\u60a3\u8005\u8a3a\u65b7\u70ba\u793e\u4ea4\u7126\u616e\u969c\u7919\uff0c\u4e26\u5728\u5165\u7d44\u6642\u8868\u73fe\u51fa\u660e\u986f\u7684\u793e\u4ea4\u7126\u616e\uff0cLSAS\u7684\u57fa\u7dda\u8a55\u5206\u81f3\u5c11\u70ba70\u3002\u5728\u7372\u5f97PALISADE-1\u7814\u7a76\u4e3b\u8981\u7d50\u679c\u5f8c\u66ab\u505c\u4e86\u672c\u7814\u7a76\u7684\u5165\u7d44\uff0c\u5171\u6709141\u540d\u60a3\u8005\u53c3\u52a0\u4e86\u7f8e\u570b\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u3002\u7368\u7acb\u7b2c\u4e09\u65b9\u751f\u7269\u7d71\u8a08\u5b78\u5bb6\u5c0d\u622a\u81f3\u66ab\u505c\u65e5\u671f\u7684\u8a66\u9a57\u4e2d\u96a8\u6a5f\u5206\u914d\u7684141\u540d\u60a3\u8005\u9032\u884c\u4e86\u4e2d\u671f\u5206\u6790\u3002\u7368\u7acb\u4e2d\u671f\u5206\u6790\u7684\u7d50\u679c\u8868\u660e\uff0c\u7e7c\u7e8cPALISADE-2\u4e0d\u6703\u662f\u7121\u6548\u7684\uff0c\u4f46\u9452\u65bc\u6062\u5fa9PALISADE-2\u6240\u6d89\u53ca\u7684\u8cbb\u7528\uff0c\u6642\u9593\u548c\u65b9\u6cd5\u7684\u5fa9\u96dc\u6027\uff0cVistagen\u6c7a\u5b9a\u6700\u4f73\u884c\u52d5\u65b9\u6848\u662f\u7d50\u675fPALISADE-2\u7814\u7a76\u3002 \u5c0d3\u671fPALISADE-2\u8a66\u9a57\u6578\u64da\u7684\u9032\u4e00\u6b65\u5206\u6790\u6b63\u5728\u9032\u884c\u4e2d\uff0c\u4e26\u8a08\u5283\u5728\u672a\u4f86\u7684\u79d1\u5b78\u6703\u8b70\u4e0a\u5c55\u793a\u9019\u4e9b\u7d50\u679c\u3002 \u95dc\u65bcFasedienol\u9f3b\u5674\u5291 Vistagen\u7684Fasedienol\uff08PH94B\uff09\u662f\u4e00\u7a2e\u9996\u5275\u7684\u5feb\u901f\u8d77\u6548\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\uff0c\u5177\u6709\u65b0\u7a4e\u7684\u4f5c\u7528\u6a5f\u5236\uff08MOA\uff09\uff0c\u53ef\u8abf\u7bc0\u8207\u6050\u61fc\u548c\u7126\u616e\u76f8\u95dc\u7684\u55c5\u89ba-\u674f\u4ec1\u6838\u795e\u7d93\u56de\u8def\uff0c\u4e26\u6e1b\u5f31\u4ea4\u611f\u81ea\u4e3b\u795e\u7d93\u7cfb\u7d71\u7684\u5f35\u529b\uff0c\u7121\u5168\u8eab\u5206\u5e03\uff0c\u7121GABA-A\u53d7\u9ad4\u589e\u5f37\u4f5c\u7528\uff0c\u4e5f\u4e0d\u76f4\u63a5\u4f5c\u7528\u65bc\u5927\u8166\u795e\u7d93\u5143\u3002Vistagen\u6b63\u5728\u958b\u767c\u5176\u7528\u65bc\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u7684 3 \u671f\u9805\u76ee\u3002Fasedienol\u7684\u65b0\u578b\u4f5c\u7528\u6a5f\u7406\u8207\u5df2\u6279\u51c6\u7684\u6240\u6709\u6297\u7126\u616e\u85e5\u7269\uff08\u5305\u62ec\u6240\u6709SSRIs\u548cSNRIs\u4ee5\u53ca\u9069\u61c9\u75c7\u5916\u8655\u65b9\u7684\u82ef\u4e8c\u6c2e\u5353\u985e\u85e5\u7269\uff09\u6709\u672c\u8cea\u5340\u5225\uff0c\u70ba\u4f4e\u5fae\u514b\u5291\u91cf\u7684\u9f3b\u5167\u7d66\u85e5\u3002 \u95dc\u65bc\u793e\u4ea4\u7126\u616e\u969c\u7919 \u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u5f71\u97ff\u8d85\u904e2500\u842c\u7f8e\u570b\u4eba\u548c1.88\u5104\u5168\u7403\u4eba\u53e3\uff0c\u5176\u4e2d\u4e2d\u570b\u81f3\u5c11\u67091130\u842c\u4eba1,2,3\u3002\u60a3\u6709\u793e\u4ea4\u7126\u616e\u969c\u7919\u7684\u4eba\u5728\u67d0\u4e9b\u793e\u4ea4\u5834\u5408\u6703\u611f\u5230\u5f37\u70c8\uff0c\u6301\u7e8c\u7684\u7126\u616e\u6216\u6050\u61fc\uff0c\u4f8b\u5982\u7d50\u8b58\u65b0\u670b\u53cb\uff0c\u5728\u5546\u52d9\u6703\u8b70\u4e0a\u767c\u8868\u8a55\u8ad6\uff0c\u7d04\u6703\uff0c\u53c3\u52a0\u5de5\u4f5c\u9762\u8a66\uff0c\u5728\u8ab2\u5802\u4e0a\u56de\u7b54\u554f\u984c\uff0c\u6216\u5728\u5546\u5e97\u8207\u6536\u9280\u54e1\u4ea4\u8ac7\u3002\u5373\u4f7f\u5728\u4eba\u524d\u505a\u65e5\u5e38\u4e8b\u60c5\uff0c\u56e0\u611f\u89ba\u5c37\u5c2c\u3001\u88ab\u8a55\u4f30\u3001\u7f9e\u8fb1\u3001\u8a55\u5224\u6216\u62d2\u7d55\uff0c\u800c\u5f15\u767c\u6df1\u523b\u7684\u7126\u616e\u6216\u5bb3\u6015\u3002\u793e\u4ea4\u7126\u616e\u969c\u7919\u53ef\u80fd\u6703\u59a8\u7919\u4e0a\u73ed\u3001\u4e0a\u5b78\u6216\u5728\u53ef\u80fd\u6d89\u53ca\u4eba\u969b\u4e92\u52d5\u7684\u60c5\u6cc1\u4e0b\u505a\u5404\u7a2e\u5404\u6a23\u7684\u4e8b\u60c5\u3002\u53ef\u80fd\u5c0e\u81f4\u56de\u907f\u548c\u6a5f\u6703\u6210\u672c\uff0c\u5f9e\u800c\u986f\u8457\u5f71\u97ff\u4e00\u500b\u4eba\u7684\u5c31\u696d\u548c\u793e\u6703\u6d3b\u52d5\uff0c\u4e26\u53ef\u80fd\u5c0d\u4ed6\u5011\u7684\u6574\u9ad4\u751f\u6d3b\u8cea\u91cf\u9020\u6210\u56b4\u91cd\u7834\u58de\u3002\u00a0 \u95dc\u65bc\u85f9\u7766\u91ab\u7642 \u85f9\u7766\u91ab\u7642\u662f\u4e00\u5bb6\u5168\u7403\u5275\u65b0\u91ab\u85e5\u79d1\u6280\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u958b\u767c\u548c\u5546\u696d\u5316\u9769\u65b0\u6027\u85e5\u7269\u3001\u6578\u5b57\u7642\u6cd5\u548c\u91ab\u85e5\u5668\u68b0\u7522\u54c1\uff0c\u4ee5\u6eff\u8db3\u5927\u4e2d\u83ef\u5730\u5340\u548c\u5168\u7403\u60a3\u8005\u5728\u773c\u79d1\u3001\u795e\u7d93\u548c\u7cbe\u795e\u7cfb\u7d71\u75be\u75c5\u6cbb\u7642\u9818\u57df\u5c1a\u672a\u6eff\u8db3\u7684\u95dc\u9375\u91ab\u7642\u9700\u6c42\u3002\u85f9\u7766\u91ab\u7642\u7684\u7ba1\u7406\u5718\u968a\u64c1\u6709\u5168\u9762\u7684\u5c08\u696d\u77e5\u8b58\u548c\u884c\u696d\u7d93\u9a57\uff0c\u4e26\u5148\u5f8c\u5728\u4e2d\u570b\u53ca\u5168\u7403\u9818\u5148\u8de8\u570b\u751f\u7269\u5236\u85e5\u516c\u53f8\u64d4\u4efb\u9ad8\u7d1a\u7ba1\u7406\u8077\u52d9\uff0c\u6210\u529f\u63a8\u9032\u548c\u4e3b\u5c0e\u5275\u65b0\u85e5\u7269\u767c\u73fe\u3001\u81e8\u5e8a\u958b\u767c\u3001\u6ce8\u518a\u4e8b\u52d9\u3001\u696d\u52d9\u62d3\u5c55\u3001\u751f\u7522\u5236\u9020\u548c\u5546\u696d\u904b\u71df\u696d\u52d9\u3002   1. National Health and Wellness Survey (NHWS), 2021.   2. Stein, D.J., Lim, C.C.W., Roest, A.M. et al. The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative. BMC Med 15, 143 (2017).   3. Frost &amp; Sullivan. January 2022. Global Market Study of CNS and Opthalmic Treatment Market, 2022. Shanghai, China.    \u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=169526\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u85f9\u7766\u91ab\u7642\u5ba3\u5e03\u5408\u4f5c\u4f19\u4f34Vistagen\u7684Fasedienol\uff08PH94B\uff09\u9f3b\u5674\u5291\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u76843\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u4e2d\u53d6\u5f97\u7a4d\u6975\u7d50\u679c - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" content=\"15\u5e74\u4f86\u793e\u4ea4\u7126\u616e\u969c\u7919\u7642\u6cd5\u5728\u7f8e\u570b\u7684\u9996\u500b\u967d\u6027\u7d50\u679c3\u671f\u7814\u7a76  \u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u4e2d\uff0cFasedienol\u7d44\u60a3\u8005\u5831\u544a\u7684\u4e3b\u89c0\u75db\u82e6\u611f\u89ba\u55ae\u4f4d\u91cf\u8868\uff08SUDS\uff09\u8a55\u5206\u8b8a\u5316\u76f8\u6bd4\u5b89\u6170\u5291\u7d44\u986f\u8457\u6539\u5584\uff08\u4e3b\u8981\u7d42\u9ede\uff0cp=0.015\uff09  \u8a66\u9a57\u4e5f\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0c\u901a\u904e\u81e8\u5e8a\u6574\u9ad4\u5370\u8c61\u6539\u5584\uff08CGI-I\uff09\u91cf\u8868\u8a55\u4f30\uff0cFasedienol\u7d44\u60a3\u8005\u7684\u61c9\u7b54\u7387\u4e5f\u986f\u8457\u9ad8\u65bc\u5b89\u6170\u5291\u7d44\uff08\u6b21\u8981\u7d42\u9ede\uff0cp=0.033\uff09\u3002  Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002  \u5168\u7403\u67091.88\u5104\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\uff0c\u5176\u4e2d\u7f8e\u570b\u8d85\u904e2500\u842c\u60a3\u8005\uff0c\u4e2d\u570b\u81f3\u5c11\u67091130\u842c\u60a3\u80051,2,3\u00a0 \u4e0a\u6d772023\u5e748\u670810\u65e5 \/\u7f8e\u901a\u793e\/ -- \u85f9\u7766\u91ab\u7642\uff08AffaMed Therapeutics\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u5408\u4f5c\u4f19\u4f34 Vistagen Therapeutics\uff08\u300cVistagen\u300d - \u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aVTGN\uff09\u4e00\u5bb6\u65e8\u5728\u6539\u8b8a\u7126\u616e\u3001\u6291\u90c1\u548c\u5176\u4ed6\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71 \uff08CNS\uff09 \u75be\u75c5\u60a3\u8005\u6cbb\u7642\u683c\u5c40\u7684\u81e8\u5e8a\u968e\u6bb5\u751f\u7269\u5236\u85e5\u516c\u53f8\uff0c \u5176PALISADE-2 \u8a55\u4f30Fasedienol \uff08PH94B\uff09 \u9f3b\u5674\u5291\u5728\u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u7642\u6548\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u76843 \u671f\u81e8\u5e8a\u8a66\u9a57\u53d6\u5f97\u4e86\u967d\u6027\u7d50\u679c\u3002\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0cFasedienol\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u5e73\u5747SUDS\u8a55\u5206\u8b8a\u5316\u6709\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff08p = 0.015\uff09\u3002\u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e4b\u9593\u6709\u986f\u8457\u5dee\u7570\uff08p = 0.033\uff09\u3002Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002 2020\u5e746\u6708\uff0c\u85f9\u7766\u91ab\u7642\u8207VistaGen\u7c3d\u8a02\u4e86\u6230\u7565\u8a31\u53ef\u548c\u5408\u4f5c\u5354\u8b70\uff0c\u7372\u5f97\u4e86PH94B\u5728\u4e2d\u570b\u3001\u97d3\u570b\u548c\u6771\u5357\u4e9e\u7684\u81e8\u5e8a\u958b\u767c\u548c\u5546\u696d\u5316\u6b0a\u76ca\u3002 \u300c\u6211\u5011\u5f88\u9ad8\u82083\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u7684\u7d50\u679c\u9032\u4e00\u6b65\u8b49\u5be6\u4e862\u671f\u7814\u7a76\u4e2d\u6240\u770b\u5230\u7684\u60c5\u6cc1\uff0c\u4e26\u986f\u793a\u4e86Fasedienol\u7684\u5de8\u5927\u6f5b\u529b\uff0c\u5176\u65b0\u7a4e\u800c\u7368\u7279\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u53ef\u4ee5\u6539\u8b8a\u7f8e\u570b\u8d85\u904e2500\u842c\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u53ca\u5168\u7403\u6578\u767e\u842c\u60a3\u8005\u7684\u6cbb\u7642\u53ef\u80fd\u6027\u300d\uff0cVistagen\u9996\u5e2d\u57f7\u884c\u5b98Shawn Singh\u8aaa\u3002\u300c\u4f5c\u70ba\u4e00\u985e\u65b0\u578b\u85e5\u7269\uff0c\u6211\u5011\u7684\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\u7ba1\u7dda\u5177\u6709\u6539\u8b8a\u773e\u591a\u6cbb\u7642\u9818\u57df\u683c\u5c40\u7684\u6f5b\u529b\u3002\u6b63\u59823\u671f\u8a66\u9a57\u6240\u8b49\u660e\u7684\u90a3\u6a23\uff0cFasedienol\u8655\u65bc\u8a72\u985e\u85e5\u7269\u7684\u9818\u5148\u5730\u4f4d\uff0c\u5176\u6f5b\u529b\u70ba\u6210\u70ba20\u591a\u5e74\u4f86\u9996\u500b\u91dd\u5c0d\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7684\u5168\u65b0\u85e5\u7269\u985e\u5225\u5960\u5b9a\u4e86\u57fa\u790e\u3002\u300d \u85f9\u7766\u91ab\u7642\u9996\u5e2d\u57f7\u884c\u5b98\u8d99\u5927\u582f\u535a\u58eb\u8a55\u8ad6\u9053\uff1a\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u770b\u5230PALISADE-2\u8a66\u9a57\u7684\u7d50\u679c\u8b49\u660e\u4e86Fasedienol\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u65b9\u9762\u7684\u6f5b\u529b\uff0c\u4e26\u671f\u5f85\u8207Vistagen\u5408\u4f5c\uff0c\u70ba\u4e2d\u570b\uff0c\u97d3\u570b\u548c\u6771\u5357\u4e9e\u65e5\u76ca\u589e\u9577\u7684\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u300d \u4e3b\u8981\u7642\u6548\u7d42\u9ede PALISADE-2\u8a66\u9a57\uff08n=141\uff09\u9054\u5230\u4e86\u4e3b\u8981\u7642\u6548\u7d42\u9ede\uff0c\u5373\u00a0Fasedienol\uff08n = 70\uff09\u6cbb\u7642\u7d44\u8207\u5b89\u6170\u5291\u7d44\uff08n = 71\uff09\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09\u7684\u5e73\u5747SUDS\u8a55\u5206\u76f8\u8f03\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u8b8a\u5316\u7684\u5dee\u7570\u3002\u8207\u5b89\u6170\u5291\u7d44\uff08LS\u5e73\u5747\u503c= -8.0\uff09\u76f8\u6bd4\uff0cFasedienol\u6cbb\u7642\u7d44SUDS\u5e73\u5747\u8a55\u5206\u8b8a\u5316\uff08\u6700\u5c0f\u4e8c\u4e58\uff08LS\uff09\u5e73\u5747\u503c= -13.8\uff09\u6709\u986f\u8457\u5dee\u7570\uff0c\u7d44\u9593\u5dee\u7570\u70ba-5.8\uff08p = 0.015\uff09\u3002 \u6b21\u8981\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e0a\u6709\u986f\u8457\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u88ab\u8a55\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba37.7%\uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba21.4%\uff08n = 71\uff09\uff08p = 0.033\uff09\u3002 \u63a2\u7d22\u6027\u7642\u6548\u7d42\u9ede 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\u95dc\u65bc\u85f9\u7766\u91ab\u7642 \u85f9\u7766\u91ab\u7642\u662f\u4e00\u5bb6\u5168\u7403\u5275\u65b0\u91ab\u85e5\u79d1\u6280\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u958b\u767c\u548c\u5546\u696d\u5316\u9769\u65b0\u6027\u85e5\u7269\u3001\u6578\u5b57\u7642\u6cd5\u548c\u91ab\u85e5\u5668\u68b0\u7522\u54c1\uff0c\u4ee5\u6eff\u8db3\u5927\u4e2d\u83ef\u5730\u5340\u548c\u5168\u7403\u60a3\u8005\u5728\u773c\u79d1\u3001\u795e\u7d93\u548c\u7cbe\u795e\u7cfb\u7d71\u75be\u75c5\u6cbb\u7642\u9818\u57df\u5c1a\u672a\u6eff\u8db3\u7684\u95dc\u9375\u91ab\u7642\u9700\u6c42\u3002\u85f9\u7766\u91ab\u7642\u7684\u7ba1\u7406\u5718\u968a\u64c1\u6709\u5168\u9762\u7684\u5c08\u696d\u77e5\u8b58\u548c\u884c\u696d\u7d93\u9a57\uff0c\u4e26\u5148\u5f8c\u5728\u4e2d\u570b\u53ca\u5168\u7403\u9818\u5148\u8de8\u570b\u751f\u7269\u5236\u85e5\u516c\u53f8\u64d4\u4efb\u9ad8\u7d1a\u7ba1\u7406\u8077\u52d9\uff0c\u6210\u529f\u63a8\u9032\u548c\u4e3b\u5c0e\u5275\u65b0\u85e5\u7269\u767c\u73fe\u3001\u81e8\u5e8a\u958b\u767c\u3001\u6ce8\u518a\u4e8b\u52d9\u3001\u696d\u52d9\u62d3\u5c55\u3001\u751f\u7522\u5236\u9020\u548c\u5546\u696d\u904b\u71df\u696d\u52d9\u3002   1. National Health and Wellness Survey (NHWS), 2021.   2. Stein, D.J., Lim, C.C.W., Roest, A.M. et al. The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative. BMC Med 15, 143 (2017).   3. Frost &amp; Sullivan. January 2022. Global Market Study of CNS and Opthalmic Treatment Market, 2022. 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- \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/?p=169526#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/?p=169526#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/logo-150.png\",\"datePublished\":\"2023-08-10T07:36:00+00:00\",\"description\":\"15\u5e74\u4f86\u793e\u4ea4\u7126\u616e\u969c\u7919\u7642\u6cd5\u5728\u7f8e\u570b\u7684\u9996\u500b\u967d\u6027\u7d50\u679c3\u671f\u7814\u7a76 \u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u4e2d\uff0cFasedienol\u7d44\u60a3\u8005\u5831\u544a\u7684\u4e3b\u89c0\u75db\u82e6\u611f\u89ba\u55ae\u4f4d\u91cf\u8868\uff08SUDS\uff09\u8a55\u5206\u8b8a\u5316\u76f8\u6bd4\u5b89\u6170\u5291\u7d44\u986f\u8457\u6539\u5584\uff08\u4e3b\u8981\u7d42\u9ede\uff0cp=0.015\uff09 \u8a66\u9a57\u4e5f\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0c\u901a\u904e\u81e8\u5e8a\u6574\u9ad4\u5370\u8c61\u6539\u5584\uff08CGI-I\uff09\u91cf\u8868\u8a55\u4f30\uff0cFasedienol\u7d44\u60a3\u8005\u7684\u61c9\u7b54\u7387\u4e5f\u986f\u8457\u9ad8\u65bc\u5b89\u6170\u5291\u7d44\uff08\u6b21\u8981\u7d42\u9ede\uff0cp=0.033\uff09\u3002 Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002 \u5168\u7403\u67091.88\u5104\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\uff0c\u5176\u4e2d\u7f8e\u570b\u8d85\u904e2500\u842c\u60a3\u8005\uff0c\u4e2d\u570b\u81f3\u5c11\u67091130\u842c\u60a3\u80051,2,3\u00a0 \u4e0a\u6d772023\u5e748\u670810\u65e5 \\\/\u7f8e\u901a\u793e\\\/ -- \u85f9\u7766\u91ab\u7642\uff08AffaMed Therapeutics\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u5408\u4f5c\u4f19\u4f34 Vistagen Therapeutics\uff08\u300cVistagen\u300d - \u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aVTGN\uff09\u4e00\u5bb6\u65e8\u5728\u6539\u8b8a\u7126\u616e\u3001\u6291\u90c1\u548c\u5176\u4ed6\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71 \uff08CNS\uff09 \u75be\u75c5\u60a3\u8005\u6cbb\u7642\u683c\u5c40\u7684\u81e8\u5e8a\u968e\u6bb5\u751f\u7269\u5236\u85e5\u516c\u53f8\uff0c \u5176PALISADE-2 \u8a55\u4f30Fasedienol \uff08PH94B\uff09 \u9f3b\u5674\u5291\u5728\u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u7642\u6548\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u76843 \u671f\u81e8\u5e8a\u8a66\u9a57\u53d6\u5f97\u4e86\u967d\u6027\u7d50\u679c\u3002\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0cFasedienol\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u5e73\u5747SUDS\u8a55\u5206\u8b8a\u5316\u6709\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff08p = 0.015\uff09\u3002\u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e4b\u9593\u6709\u986f\u8457\u5dee\u7570\uff08p = 0.033\uff09\u3002Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002 2020\u5e746\u6708\uff0c\u85f9\u7766\u91ab\u7642\u8207VistaGen\u7c3d\u8a02\u4e86\u6230\u7565\u8a31\u53ef\u548c\u5408\u4f5c\u5354\u8b70\uff0c\u7372\u5f97\u4e86PH94B\u5728\u4e2d\u570b\u3001\u97d3\u570b\u548c\u6771\u5357\u4e9e\u7684\u81e8\u5e8a\u958b\u767c\u548c\u5546\u696d\u5316\u6b0a\u76ca\u3002 \u300c\u6211\u5011\u5f88\u9ad8\u82083\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u7684\u7d50\u679c\u9032\u4e00\u6b65\u8b49\u5be6\u4e862\u671f\u7814\u7a76\u4e2d\u6240\u770b\u5230\u7684\u60c5\u6cc1\uff0c\u4e26\u986f\u793a\u4e86Fasedienol\u7684\u5de8\u5927\u6f5b\u529b\uff0c\u5176\u65b0\u7a4e\u800c\u7368\u7279\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u53ef\u4ee5\u6539\u8b8a\u7f8e\u570b\u8d85\u904e2500\u842c\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u53ca\u5168\u7403\u6578\u767e\u842c\u60a3\u8005\u7684\u6cbb\u7642\u53ef\u80fd\u6027\u300d\uff0cVistagen\u9996\u5e2d\u57f7\u884c\u5b98Shawn Singh\u8aaa\u3002\u300c\u4f5c\u70ba\u4e00\u985e\u65b0\u578b\u85e5\u7269\uff0c\u6211\u5011\u7684\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\u7ba1\u7dda\u5177\u6709\u6539\u8b8a\u773e\u591a\u6cbb\u7642\u9818\u57df\u683c\u5c40\u7684\u6f5b\u529b\u3002\u6b63\u59823\u671f\u8a66\u9a57\u6240\u8b49\u660e\u7684\u90a3\u6a23\uff0cFasedienol\u8655\u65bc\u8a72\u985e\u85e5\u7269\u7684\u9818\u5148\u5730\u4f4d\uff0c\u5176\u6f5b\u529b\u70ba\u6210\u70ba20\u591a\u5e74\u4f86\u9996\u500b\u91dd\u5c0d\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7684\u5168\u65b0\u85e5\u7269\u985e\u5225\u5960\u5b9a\u4e86\u57fa\u790e\u3002\u300d \u85f9\u7766\u91ab\u7642\u9996\u5e2d\u57f7\u884c\u5b98\u8d99\u5927\u582f\u535a\u58eb\u8a55\u8ad6\u9053\uff1a\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u770b\u5230PALISADE-2\u8a66\u9a57\u7684\u7d50\u679c\u8b49\u660e\u4e86Fasedienol\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u65b9\u9762\u7684\u6f5b\u529b\uff0c\u4e26\u671f\u5f85\u8207Vistagen\u5408\u4f5c\uff0c\u70ba\u4e2d\u570b\uff0c\u97d3\u570b\u548c\u6771\u5357\u4e9e\u65e5\u76ca\u589e\u9577\u7684\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u300d \u4e3b\u8981\u7642\u6548\u7d42\u9ede PALISADE-2\u8a66\u9a57\uff08n=141\uff09\u9054\u5230\u4e86\u4e3b\u8981\u7642\u6548\u7d42\u9ede\uff0c\u5373\u00a0Fasedienol\uff08n = 70\uff09\u6cbb\u7642\u7d44\u8207\u5b89\u6170\u5291\u7d44\uff08n = 71\uff09\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09\u7684\u5e73\u5747SUDS\u8a55\u5206\u76f8\u8f03\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u8b8a\u5316\u7684\u5dee\u7570\u3002\u8207\u5b89\u6170\u5291\u7d44\uff08LS\u5e73\u5747\u503c= -8.0\uff09\u76f8\u6bd4\uff0cFasedienol\u6cbb\u7642\u7d44SUDS\u5e73\u5747\u8a55\u5206\u8b8a\u5316\uff08\u6700\u5c0f\u4e8c\u4e58\uff08LS\uff09\u5e73\u5747\u503c= -13.8\uff09\u6709\u986f\u8457\u5dee\u7570\uff0c\u7d44\u9593\u5dee\u7570\u70ba-5.8\uff08p = 0.015\uff09\u3002 \u6b21\u8981\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e0a\u6709\u986f\u8457\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u88ab\u8a55\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba37.7%\uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba21.4%\uff08n = 71\uff09\uff08p = 0.033\uff09\u3002 \u63a2\u7d22\u6027\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e00\u500b\u91cd\u8981\u7684\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u901a\u904e\u60a3\u8005\u5c0d\u75c5\u60c5\u8b8a\u5316\u7684\u7e3d\u9ad4\u5370\u8c61\uff08PGI-C\uff09\u91cf\u8868\u8861\u91cf\u7684Fasedienol\u548c\u5b89\u6170\u5291\u4e4b\u9593\u61c9\u7b54\u7387\u7684\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u81ea\u6211\u8a55\u50f9\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba40.6% \uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n = 71\uff09\uff08p = 0.003\uff09\u3002 \u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u5169\u7d44\u9593\u5f9e\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u5230\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09SUDS\u8a55\u5206\u6539\u5584\u81f3\u5c1120\u5206\uff08\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u6539\u5584\uff09\u7684\u60a3\u8005\u6bd4\u4f8b\uff0cFasedieno\u7d44\u70ba35.7%\uff08n=70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n=71\uff09\uff0c\u5169\u7d44\u4e4b\u9593\u6709\u986f\u8457\u7d71\u8a08\u5b78\u5dee\u7570\uff08p=0.020\uff09\u3002 \u5b89\u5168\u6027 \u7814\u7a76\u986f\u793aFasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u5831\u544a\u91cd\u5ea6\u6216\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08AEs\uff09\u3002\u5728\u6574\u500b\u7814\u7a76\u4e2d\uff0c\u6240\u6709\u6cbb\u7642\u671f\u9593\u51fa\u73fe\u7684\u4e0d\u826f\u4e8b\u4ef6\u5747\u70ba\u8f15\u5ea6\u6216\u4e2d\u5ea6\u3002\u5728Fasedienol\u6cbb\u7642\u7d44\u4e2d\uff0c\u672a\u5831\u544a\u767c\u751f\u7387\u8d85\u904e2%\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002 \u95dc\u65bc 3 \u671f PALISADE-2 \u8a66\u9a57 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National Health and Wellness Survey (NHWS), 2021. 2. Stein, D.J., Lim, C.C.W., Roest, A.M. et al. The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative. BMC Med 15, 143 (2017). 3. Frost &amp; Sullivan. January 2022. Global Market Study of CNS and Opthalmic Treatment Market, 2022. 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\u8a66\u9a57\u4e5f\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0c\u901a\u904e\u81e8\u5e8a\u6574\u9ad4\u5370\u8c61\u6539\u5584\uff08CGI-I\uff09\u91cf\u8868\u8a55\u4f30\uff0cFasedienol\u7d44\u60a3\u8005\u7684\u61c9\u7b54\u7387\u4e5f\u986f\u8457\u9ad8\u65bc\u5b89\u6170\u5291\u7d44\uff08\u6b21\u8981\u7d42\u9ede\uff0cp=0.033\uff09\u3002  Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002  \u5168\u7403\u67091.88\u5104\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\uff0c\u5176\u4e2d\u7f8e\u570b\u8d85\u904e2500\u842c\u60a3\u8005\uff0c\u4e2d\u570b\u81f3\u5c11\u67091130\u842c\u60a3\u80051,2,3\u00a0 \u4e0a\u6d772023\u5e748\u670810\u65e5 \/\u7f8e\u901a\u793e\/ -- \u85f9\u7766\u91ab\u7642\uff08AffaMed Therapeutics\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u5408\u4f5c\u4f19\u4f34 Vistagen Therapeutics\uff08\u300cVistagen\u300d - \u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aVTGN\uff09\u4e00\u5bb6\u65e8\u5728\u6539\u8b8a\u7126\u616e\u3001\u6291\u90c1\u548c\u5176\u4ed6\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71 \uff08CNS\uff09 \u75be\u75c5\u60a3\u8005\u6cbb\u7642\u683c\u5c40\u7684\u81e8\u5e8a\u968e\u6bb5\u751f\u7269\u5236\u85e5\u516c\u53f8\uff0c \u5176PALISADE-2 \u8a55\u4f30Fasedienol \uff08PH94B\uff09 \u9f3b\u5674\u5291\u5728\u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u7642\u6548\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u76843 \u671f\u81e8\u5e8a\u8a66\u9a57\u53d6\u5f97\u4e86\u967d\u6027\u7d50\u679c\u3002\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0cFasedienol\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u5e73\u5747SUDS\u8a55\u5206\u8b8a\u5316\u6709\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff08p = 0.015\uff09\u3002\u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e4b\u9593\u6709\u986f\u8457\u5dee\u7570\uff08p = 0.033\uff09\u3002Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002 2020\u5e746\u6708\uff0c\u85f9\u7766\u91ab\u7642\u8207VistaGen\u7c3d\u8a02\u4e86\u6230\u7565\u8a31\u53ef\u548c\u5408\u4f5c\u5354\u8b70\uff0c\u7372\u5f97\u4e86PH94B\u5728\u4e2d\u570b\u3001\u97d3\u570b\u548c\u6771\u5357\u4e9e\u7684\u81e8\u5e8a\u958b\u767c\u548c\u5546\u696d\u5316\u6b0a\u76ca\u3002 \u300c\u6211\u5011\u5f88\u9ad8\u82083\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u7684\u7d50\u679c\u9032\u4e00\u6b65\u8b49\u5be6\u4e862\u671f\u7814\u7a76\u4e2d\u6240\u770b\u5230\u7684\u60c5\u6cc1\uff0c\u4e26\u986f\u793a\u4e86Fasedienol\u7684\u5de8\u5927\u6f5b\u529b\uff0c\u5176\u65b0\u7a4e\u800c\u7368\u7279\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u53ef\u4ee5\u6539\u8b8a\u7f8e\u570b\u8d85\u904e2500\u842c\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u53ca\u5168\u7403\u6578\u767e\u842c\u60a3\u8005\u7684\u6cbb\u7642\u53ef\u80fd\u6027\u300d\uff0cVistagen\u9996\u5e2d\u57f7\u884c\u5b98Shawn Singh\u8aaa\u3002\u300c\u4f5c\u70ba\u4e00\u985e\u65b0\u578b\u85e5\u7269\uff0c\u6211\u5011\u7684\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\u7ba1\u7dda\u5177\u6709\u6539\u8b8a\u773e\u591a\u6cbb\u7642\u9818\u57df\u683c\u5c40\u7684\u6f5b\u529b\u3002\u6b63\u59823\u671f\u8a66\u9a57\u6240\u8b49\u660e\u7684\u90a3\u6a23\uff0cFasedienol\u8655\u65bc\u8a72\u985e\u85e5\u7269\u7684\u9818\u5148\u5730\u4f4d\uff0c\u5176\u6f5b\u529b\u70ba\u6210\u70ba20\u591a\u5e74\u4f86\u9996\u500b\u91dd\u5c0d\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7684\u5168\u65b0\u85e5\u7269\u985e\u5225\u5960\u5b9a\u4e86\u57fa\u790e\u3002\u300d \u85f9\u7766\u91ab\u7642\u9996\u5e2d\u57f7\u884c\u5b98\u8d99\u5927\u582f\u535a\u58eb\u8a55\u8ad6\u9053\uff1a\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u770b\u5230PALISADE-2\u8a66\u9a57\u7684\u7d50\u679c\u8b49\u660e\u4e86Fasedienol\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u65b9\u9762\u7684\u6f5b\u529b\uff0c\u4e26\u671f\u5f85\u8207Vistagen\u5408\u4f5c\uff0c\u70ba\u4e2d\u570b\uff0c\u97d3\u570b\u548c\u6771\u5357\u4e9e\u65e5\u76ca\u589e\u9577\u7684\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u300d \u4e3b\u8981\u7642\u6548\u7d42\u9ede PALISADE-2\u8a66\u9a57\uff08n=141\uff09\u9054\u5230\u4e86\u4e3b\u8981\u7642\u6548\u7d42\u9ede\uff0c\u5373\u00a0Fasedienol\uff08n = 70\uff09\u6cbb\u7642\u7d44\u8207\u5b89\u6170\u5291\u7d44\uff08n = 71\uff09\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09\u7684\u5e73\u5747SUDS\u8a55\u5206\u76f8\u8f03\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u8b8a\u5316\u7684\u5dee\u7570\u3002\u8207\u5b89\u6170\u5291\u7d44\uff08LS\u5e73\u5747\u503c= -8.0\uff09\u76f8\u6bd4\uff0cFasedienol\u6cbb\u7642\u7d44SUDS\u5e73\u5747\u8a55\u5206\u8b8a\u5316\uff08\u6700\u5c0f\u4e8c\u4e58\uff08LS\uff09\u5e73\u5747\u503c= -13.8\uff09\u6709\u986f\u8457\u5dee\u7570\uff0c\u7d44\u9593\u5dee\u7570\u70ba-5.8\uff08p = 0.015\uff09\u3002 \u6b21\u8981\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e0a\u6709\u986f\u8457\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u88ab\u8a55\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba37.7%\uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba21.4%\uff08n = 71\uff09\uff08p = 0.033\uff09\u3002 \u63a2\u7d22\u6027\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e00\u500b\u91cd\u8981\u7684\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u901a\u904e\u60a3\u8005\u5c0d\u75c5\u60c5\u8b8a\u5316\u7684\u7e3d\u9ad4\u5370\u8c61\uff08PGI-C\uff09\u91cf\u8868\u8861\u91cf\u7684Fasedienol\u548c\u5b89\u6170\u5291\u4e4b\u9593\u61c9\u7b54\u7387\u7684\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u81ea\u6211\u8a55\u50f9\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba40.6% \uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n = 71\uff09\uff08p = 0.003\uff09\u3002 \u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u5169\u7d44\u9593\u5f9e\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u5230\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09SUDS\u8a55\u5206\u6539\u5584\u81f3\u5c1120\u5206\uff08\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u6539\u5584\uff09\u7684\u60a3\u8005\u6bd4\u4f8b\uff0cFasedieno\u7d44\u70ba35.7%\uff08n=70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n=71\uff09\uff0c\u5169\u7d44\u4e4b\u9593\u6709\u986f\u8457\u7d71\u8a08\u5b78\u5dee\u7570\uff08p=0.020\uff09\u3002 \u5b89\u5168\u6027 \u7814\u7a76\u986f\u793aFasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u5831\u544a\u91cd\u5ea6\u6216\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08AEs\uff09\u3002\u5728\u6574\u500b\u7814\u7a76\u4e2d\uff0c\u6240\u6709\u6cbb\u7642\u671f\u9593\u51fa\u73fe\u7684\u4e0d\u826f\u4e8b\u4ef6\u5747\u70ba\u8f15\u5ea6\u6216\u4e2d\u5ea6\u3002\u5728Fasedienol\u6cbb\u7642\u7d44\u4e2d\uff0c\u672a\u5831\u544a\u767c\u751f\u7387\u8d85\u904e2%\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002 \u95dc\u65bc 3 \u671f PALISADE-2 \u8a66\u9a57 PALISADE-2\u662f\u4e00\u9805\u5728\u6210\u5e74\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u4e2d\u958b\u5c55\u7684\u591a\u4e2d\u5fc3\uff0c\u96a8\u6a5f\uff0c\u96d9\u76f2\uff0c\u5b89\u6170\u5291\u5c0d\u7167\u76843\u671f\u81e8\u5e8a\u7814\u7a76\u3002\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30Fasedienol\u6025\u6027\u4f7f\u7528\u5728\u6a21\u64ec\u5f15\u767c\u7126\u616e\u7684\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u7de9\u89e3\u6210\u5e74\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7126\u616e\u75c7\u72c0\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u4f7f\u7528\u60a3\u8005\u5831\u544a\u7684SUDS\u8a55\u5206\u9032\u884c\u8a55\u4f30\u3002 \u5165\u7d44\u7684\u60a3\u8005\u8a3a\u65b7\u70ba\u793e\u4ea4\u7126\u616e\u969c\u7919\uff0c\u4e26\u5728\u5165\u7d44\u6642\u8868\u73fe\u51fa\u660e\u986f\u7684\u793e\u4ea4\u7126\u616e\uff0cLSAS\u7684\u57fa\u7dda\u8a55\u5206\u81f3\u5c11\u70ba70\u3002\u5728\u7372\u5f97PALISADE-1\u7814\u7a76\u4e3b\u8981\u7d50\u679c\u5f8c\u66ab\u505c\u4e86\u672c\u7814\u7a76\u7684\u5165\u7d44\uff0c\u5171\u6709141\u540d\u60a3\u8005\u53c3\u52a0\u4e86\u7f8e\u570b\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u3002\u7368\u7acb\u7b2c\u4e09\u65b9\u751f\u7269\u7d71\u8a08\u5b78\u5bb6\u5c0d\u622a\u81f3\u66ab\u505c\u65e5\u671f\u7684\u8a66\u9a57\u4e2d\u96a8\u6a5f\u5206\u914d\u7684141\u540d\u60a3\u8005\u9032\u884c\u4e86\u4e2d\u671f\u5206\u6790\u3002\u7368\u7acb\u4e2d\u671f\u5206\u6790\u7684\u7d50\u679c\u8868\u660e\uff0c\u7e7c\u7e8cPALISADE-2\u4e0d\u6703\u662f\u7121\u6548\u7684\uff0c\u4f46\u9452\u65bc\u6062\u5fa9PALISADE-2\u6240\u6d89\u53ca\u7684\u8cbb\u7528\uff0c\u6642\u9593\u548c\u65b9\u6cd5\u7684\u5fa9\u96dc\u6027\uff0cVistagen\u6c7a\u5b9a\u6700\u4f73\u884c\u52d5\u65b9\u6848\u662f\u7d50\u675fPALISADE-2\u7814\u7a76\u3002 \u5c0d3\u671fPALISADE-2\u8a66\u9a57\u6578\u64da\u7684\u9032\u4e00\u6b65\u5206\u6790\u6b63\u5728\u9032\u884c\u4e2d\uff0c\u4e26\u8a08\u5283\u5728\u672a\u4f86\u7684\u79d1\u5b78\u6703\u8b70\u4e0a\u5c55\u793a\u9019\u4e9b\u7d50\u679c\u3002 \u95dc\u65bcFasedienol\u9f3b\u5674\u5291 Vistagen\u7684Fasedienol\uff08PH94B\uff09\u662f\u4e00\u7a2e\u9996\u5275\u7684\u5feb\u901f\u8d77\u6548\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\uff0c\u5177\u6709\u65b0\u7a4e\u7684\u4f5c\u7528\u6a5f\u5236\uff08MOA\uff09\uff0c\u53ef\u8abf\u7bc0\u8207\u6050\u61fc\u548c\u7126\u616e\u76f8\u95dc\u7684\u55c5\u89ba-\u674f\u4ec1\u6838\u795e\u7d93\u56de\u8def\uff0c\u4e26\u6e1b\u5f31\u4ea4\u611f\u81ea\u4e3b\u795e\u7d93\u7cfb\u7d71\u7684\u5f35\u529b\uff0c\u7121\u5168\u8eab\u5206\u5e03\uff0c\u7121GABA-A\u53d7\u9ad4\u589e\u5f37\u4f5c\u7528\uff0c\u4e5f\u4e0d\u76f4\u63a5\u4f5c\u7528\u65bc\u5927\u8166\u795e\u7d93\u5143\u3002Vistagen\u6b63\u5728\u958b\u767c\u5176\u7528\u65bc\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u7684 3 \u671f\u9805\u76ee\u3002Fasedienol\u7684\u65b0\u578b\u4f5c\u7528\u6a5f\u7406\u8207\u5df2\u6279\u51c6\u7684\u6240\u6709\u6297\u7126\u616e\u85e5\u7269\uff08\u5305\u62ec\u6240\u6709SSRIs\u548cSNRIs\u4ee5\u53ca\u9069\u61c9\u75c7\u5916\u8655\u65b9\u7684\u82ef\u4e8c\u6c2e\u5353\u985e\u85e5\u7269\uff09\u6709\u672c\u8cea\u5340\u5225\uff0c\u70ba\u4f4e\u5fae\u514b\u5291\u91cf\u7684\u9f3b\u5167\u7d66\u85e5\u3002 \u95dc\u65bc\u793e\u4ea4\u7126\u616e\u969c\u7919 \u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u5f71\u97ff\u8d85\u904e2500\u842c\u7f8e\u570b\u4eba\u548c1.88\u5104\u5168\u7403\u4eba\u53e3\uff0c\u5176\u4e2d\u4e2d\u570b\u81f3\u5c11\u67091130\u842c\u4eba1,2,3\u3002\u60a3\u6709\u793e\u4ea4\u7126\u616e\u969c\u7919\u7684\u4eba\u5728\u67d0\u4e9b\u793e\u4ea4\u5834\u5408\u6703\u611f\u5230\u5f37\u70c8\uff0c\u6301\u7e8c\u7684\u7126\u616e\u6216\u6050\u61fc\uff0c\u4f8b\u5982\u7d50\u8b58\u65b0\u670b\u53cb\uff0c\u5728\u5546\u52d9\u6703\u8b70\u4e0a\u767c\u8868\u8a55\u8ad6\uff0c\u7d04\u6703\uff0c\u53c3\u52a0\u5de5\u4f5c\u9762\u8a66\uff0c\u5728\u8ab2\u5802\u4e0a\u56de\u7b54\u554f\u984c\uff0c\u6216\u5728\u5546\u5e97\u8207\u6536\u9280\u54e1\u4ea4\u8ac7\u3002\u5373\u4f7f\u5728\u4eba\u524d\u505a\u65e5\u5e38\u4e8b\u60c5\uff0c\u56e0\u611f\u89ba\u5c37\u5c2c\u3001\u88ab\u8a55\u4f30\u3001\u7f9e\u8fb1\u3001\u8a55\u5224\u6216\u62d2\u7d55\uff0c\u800c\u5f15\u767c\u6df1\u523b\u7684\u7126\u616e\u6216\u5bb3\u6015\u3002\u793e\u4ea4\u7126\u616e\u969c\u7919\u53ef\u80fd\u6703\u59a8\u7919\u4e0a\u73ed\u3001\u4e0a\u5b78\u6216\u5728\u53ef\u80fd\u6d89\u53ca\u4eba\u969b\u4e92\u52d5\u7684\u60c5\u6cc1\u4e0b\u505a\u5404\u7a2e\u5404\u6a23\u7684\u4e8b\u60c5\u3002\u53ef\u80fd\u5c0e\u81f4\u56de\u907f\u548c\u6a5f\u6703\u6210\u672c\uff0c\u5f9e\u800c\u986f\u8457\u5f71\u97ff\u4e00\u500b\u4eba\u7684\u5c31\u696d\u548c\u793e\u6703\u6d3b\u52d5\uff0c\u4e26\u53ef\u80fd\u5c0d\u4ed6\u5011\u7684\u6574\u9ad4\u751f\u6d3b\u8cea\u91cf\u9020\u6210\u56b4\u91cd\u7834\u58de\u3002\u00a0 \u95dc\u65bc\u85f9\u7766\u91ab\u7642 \u85f9\u7766\u91ab\u7642\u662f\u4e00\u5bb6\u5168\u7403\u5275\u65b0\u91ab\u85e5\u79d1\u6280\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u958b\u767c\u548c\u5546\u696d\u5316\u9769\u65b0\u6027\u85e5\u7269\u3001\u6578\u5b57\u7642\u6cd5\u548c\u91ab\u85e5\u5668\u68b0\u7522\u54c1\uff0c\u4ee5\u6eff\u8db3\u5927\u4e2d\u83ef\u5730\u5340\u548c\u5168\u7403\u60a3\u8005\u5728\u773c\u79d1\u3001\u795e\u7d93\u548c\u7cbe\u795e\u7cfb\u7d71\u75be\u75c5\u6cbb\u7642\u9818\u57df\u5c1a\u672a\u6eff\u8db3\u7684\u95dc\u9375\u91ab\u7642\u9700\u6c42\u3002\u85f9\u7766\u91ab\u7642\u7684\u7ba1\u7406\u5718\u968a\u64c1\u6709\u5168\u9762\u7684\u5c08\u696d\u77e5\u8b58\u548c\u884c\u696d\u7d93\u9a57\uff0c\u4e26\u5148\u5f8c\u5728\u4e2d\u570b\u53ca\u5168\u7403\u9818\u5148\u8de8\u570b\u751f\u7269\u5236\u85e5\u516c\u53f8\u64d4\u4efb\u9ad8\u7d1a\u7ba1\u7406\u8077\u52d9\uff0c\u6210\u529f\u63a8\u9032\u548c\u4e3b\u5c0e\u5275\u65b0\u85e5\u7269\u767c\u73fe\u3001\u81e8\u5e8a\u958b\u767c\u3001\u6ce8\u518a\u4e8b\u52d9\u3001\u696d\u52d9\u62d3\u5c55\u3001\u751f\u7522\u5236\u9020\u548c\u5546\u696d\u904b\u71df\u696d\u52d9\u3002   1. National Health and Wellness Survey (NHWS), 2021.   2. Stein, D.J., Lim, C.C.W., Roest, A.M. et al. The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative. BMC Med 15, 143 (2017).   3. Frost &amp; Sullivan. January 2022. Global Market Study of CNS and Opthalmic Treatment Market, 2022. Shanghai, China.    \u00a0","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/pingtungtimes.com.tw\/?p=169526","og_locale":"zh_TW","og_type":"article","og_title":"\u85f9\u7766\u91ab\u7642\u5ba3\u5e03\u5408\u4f5c\u4f19\u4f34Vistagen\u7684Fasedienol\uff08PH94B\uff09\u9f3b\u5674\u5291\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u76843\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u4e2d\u53d6\u5f97\u7a4d\u6975\u7d50\u679c - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831","og_description":"15\u5e74\u4f86\u793e\u4ea4\u7126\u616e\u969c\u7919\u7642\u6cd5\u5728\u7f8e\u570b\u7684\u9996\u500b\u967d\u6027\u7d50\u679c3\u671f\u7814\u7a76  \u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u4e2d\uff0cFasedienol\u7d44\u60a3\u8005\u5831\u544a\u7684\u4e3b\u89c0\u75db\u82e6\u611f\u89ba\u55ae\u4f4d\u91cf\u8868\uff08SUDS\uff09\u8a55\u5206\u8b8a\u5316\u76f8\u6bd4\u5b89\u6170\u5291\u7d44\u986f\u8457\u6539\u5584\uff08\u4e3b\u8981\u7d42\u9ede\uff0cp=0.015\uff09  \u8a66\u9a57\u4e5f\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0c\u901a\u904e\u81e8\u5e8a\u6574\u9ad4\u5370\u8c61\u6539\u5584\uff08CGI-I\uff09\u91cf\u8868\u8a55\u4f30\uff0cFasedienol\u7d44\u60a3\u8005\u7684\u61c9\u7b54\u7387\u4e5f\u986f\u8457\u9ad8\u65bc\u5b89\u6170\u5291\u7d44\uff08\u6b21\u8981\u7d42\u9ede\uff0cp=0.033\uff09\u3002  Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002  \u5168\u7403\u67091.88\u5104\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\uff0c\u5176\u4e2d\u7f8e\u570b\u8d85\u904e2500\u842c\u60a3\u8005\uff0c\u4e2d\u570b\u81f3\u5c11\u67091130\u842c\u60a3\u80051,2,3\u00a0 \u4e0a\u6d772023\u5e748\u670810\u65e5 \/\u7f8e\u901a\u793e\/ -- \u85f9\u7766\u91ab\u7642\uff08AffaMed Therapeutics\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u5408\u4f5c\u4f19\u4f34 Vistagen Therapeutics\uff08\u300cVistagen\u300d - \u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aVTGN\uff09\u4e00\u5bb6\u65e8\u5728\u6539\u8b8a\u7126\u616e\u3001\u6291\u90c1\u548c\u5176\u4ed6\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71 \uff08CNS\uff09 \u75be\u75c5\u60a3\u8005\u6cbb\u7642\u683c\u5c40\u7684\u81e8\u5e8a\u968e\u6bb5\u751f\u7269\u5236\u85e5\u516c\u53f8\uff0c \u5176PALISADE-2 \u8a55\u4f30Fasedienol \uff08PH94B\uff09 \u9f3b\u5674\u5291\u5728\u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u7642\u6548\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u76843 \u671f\u81e8\u5e8a\u8a66\u9a57\u53d6\u5f97\u4e86\u967d\u6027\u7d50\u679c\u3002\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0cFasedienol\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u5e73\u5747SUDS\u8a55\u5206\u8b8a\u5316\u6709\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff08p = 0.015\uff09\u3002\u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e4b\u9593\u6709\u986f\u8457\u5dee\u7570\uff08p = 0.033\uff09\u3002Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002 2020\u5e746\u6708\uff0c\u85f9\u7766\u91ab\u7642\u8207VistaGen\u7c3d\u8a02\u4e86\u6230\u7565\u8a31\u53ef\u548c\u5408\u4f5c\u5354\u8b70\uff0c\u7372\u5f97\u4e86PH94B\u5728\u4e2d\u570b\u3001\u97d3\u570b\u548c\u6771\u5357\u4e9e\u7684\u81e8\u5e8a\u958b\u767c\u548c\u5546\u696d\u5316\u6b0a\u76ca\u3002 \u300c\u6211\u5011\u5f88\u9ad8\u82083\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u7684\u7d50\u679c\u9032\u4e00\u6b65\u8b49\u5be6\u4e862\u671f\u7814\u7a76\u4e2d\u6240\u770b\u5230\u7684\u60c5\u6cc1\uff0c\u4e26\u986f\u793a\u4e86Fasedienol\u7684\u5de8\u5927\u6f5b\u529b\uff0c\u5176\u65b0\u7a4e\u800c\u7368\u7279\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u53ef\u4ee5\u6539\u8b8a\u7f8e\u570b\u8d85\u904e2500\u842c\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u53ca\u5168\u7403\u6578\u767e\u842c\u60a3\u8005\u7684\u6cbb\u7642\u53ef\u80fd\u6027\u300d\uff0cVistagen\u9996\u5e2d\u57f7\u884c\u5b98Shawn Singh\u8aaa\u3002\u300c\u4f5c\u70ba\u4e00\u985e\u65b0\u578b\u85e5\u7269\uff0c\u6211\u5011\u7684\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\u7ba1\u7dda\u5177\u6709\u6539\u8b8a\u773e\u591a\u6cbb\u7642\u9818\u57df\u683c\u5c40\u7684\u6f5b\u529b\u3002\u6b63\u59823\u671f\u8a66\u9a57\u6240\u8b49\u660e\u7684\u90a3\u6a23\uff0cFasedienol\u8655\u65bc\u8a72\u985e\u85e5\u7269\u7684\u9818\u5148\u5730\u4f4d\uff0c\u5176\u6f5b\u529b\u70ba\u6210\u70ba20\u591a\u5e74\u4f86\u9996\u500b\u91dd\u5c0d\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7684\u5168\u65b0\u85e5\u7269\u985e\u5225\u5960\u5b9a\u4e86\u57fa\u790e\u3002\u300d \u85f9\u7766\u91ab\u7642\u9996\u5e2d\u57f7\u884c\u5b98\u8d99\u5927\u582f\u535a\u58eb\u8a55\u8ad6\u9053\uff1a\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u770b\u5230PALISADE-2\u8a66\u9a57\u7684\u7d50\u679c\u8b49\u660e\u4e86Fasedienol\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u65b9\u9762\u7684\u6f5b\u529b\uff0c\u4e26\u671f\u5f85\u8207Vistagen\u5408\u4f5c\uff0c\u70ba\u4e2d\u570b\uff0c\u97d3\u570b\u548c\u6771\u5357\u4e9e\u65e5\u76ca\u589e\u9577\u7684\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u300d \u4e3b\u8981\u7642\u6548\u7d42\u9ede PALISADE-2\u8a66\u9a57\uff08n=141\uff09\u9054\u5230\u4e86\u4e3b\u8981\u7642\u6548\u7d42\u9ede\uff0c\u5373\u00a0Fasedienol\uff08n = 70\uff09\u6cbb\u7642\u7d44\u8207\u5b89\u6170\u5291\u7d44\uff08n = 71\uff09\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09\u7684\u5e73\u5747SUDS\u8a55\u5206\u76f8\u8f03\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u8b8a\u5316\u7684\u5dee\u7570\u3002\u8207\u5b89\u6170\u5291\u7d44\uff08LS\u5e73\u5747\u503c= -8.0\uff09\u76f8\u6bd4\uff0cFasedienol\u6cbb\u7642\u7d44SUDS\u5e73\u5747\u8a55\u5206\u8b8a\u5316\uff08\u6700\u5c0f\u4e8c\u4e58\uff08LS\uff09\u5e73\u5747\u503c= -13.8\uff09\u6709\u986f\u8457\u5dee\u7570\uff0c\u7d44\u9593\u5dee\u7570\u70ba-5.8\uff08p = 0.015\uff09\u3002 \u6b21\u8981\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e0a\u6709\u986f\u8457\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u88ab\u8a55\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba37.7%\uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba21.4%\uff08n = 71\uff09\uff08p = 0.033\uff09\u3002 \u63a2\u7d22\u6027\u7642\u6548\u7d42\u9ede 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  1. National Health and Wellness Survey (NHWS), 2021.   2. Stein, D.J., Lim, C.C.W., Roest, A.M. et al. The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative. BMC Med 15, 143 (2017).   3. Frost &amp; Sullivan. January 2022. Global Market Study of CNS and Opthalmic Treatment Market, 2022. 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\u8a66\u9a57\u4e5f\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0c\u901a\u904e\u81e8\u5e8a\u6574\u9ad4\u5370\u8c61\u6539\u5584\uff08CGI-I\uff09\u91cf\u8868\u8a55\u4f30\uff0cFasedienol\u7d44\u60a3\u8005\u7684\u61c9\u7b54\u7387\u4e5f\u986f\u8457\u9ad8\u65bc\u5b89\u6170\u5291\u7d44\uff08\u6b21\u8981\u7d42\u9ede\uff0cp=0.033\uff09\u3002 Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002 \u5168\u7403\u67091.88\u5104\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\uff0c\u5176\u4e2d\u7f8e\u570b\u8d85\u904e2500\u842c\u60a3\u8005\uff0c\u4e2d\u570b\u81f3\u5c11\u67091130\u842c\u60a3\u80051,2,3\u00a0 \u4e0a\u6d772023\u5e748\u670810\u65e5 \/\u7f8e\u901a\u793e\/ -- \u85f9\u7766\u91ab\u7642\uff08AffaMed Therapeutics\uff09\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u5408\u4f5c\u4f19\u4f34 Vistagen Therapeutics\uff08\u300cVistagen\u300d - \u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aVTGN\uff09\u4e00\u5bb6\u65e8\u5728\u6539\u8b8a\u7126\u616e\u3001\u6291\u90c1\u548c\u5176\u4ed6\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71 \uff08CNS\uff09 \u75be\u75c5\u60a3\u8005\u6cbb\u7642\u683c\u5c40\u7684\u81e8\u5e8a\u968e\u6bb5\u751f\u7269\u5236\u85e5\u516c\u53f8\uff0c \u5176PALISADE-2 \u8a55\u4f30Fasedienol \uff08PH94B\uff09 \u9f3b\u5674\u5291\u5728\u793e\u4ea4\u7126\u616e\u969c\u7919\uff08SAD\uff09\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u7642\u6548\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u76843 \u671f\u81e8\u5e8a\u8a66\u9a57\u53d6\u5f97\u4e86\u967d\u6027\u7d50\u679c\u3002\u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0cFasedienol\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u5e73\u5747SUDS\u8a55\u5206\u8b8a\u5316\u6709\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff08p = 0.015\uff09\u3002\u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e4b\u9593\u6709\u986f\u8457\u5dee\u7570\uff08p = 0.033\uff09\u3002Fasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e26\u986f\u793a\u51fa\u8207\u4e4b\u524d\u6240\u6709\u8a66\u9a57\u4e00\u81f4\u7684\u826f\u597d\u5b89\u5168\u6027\u3002 2020\u5e746\u6708\uff0c\u85f9\u7766\u91ab\u7642\u8207VistaGen\u7c3d\u8a02\u4e86\u6230\u7565\u8a31\u53ef\u548c\u5408\u4f5c\u5354\u8b70\uff0c\u7372\u5f97\u4e86PH94B\u5728\u4e2d\u570b\u3001\u97d3\u570b\u548c\u6771\u5357\u4e9e\u7684\u81e8\u5e8a\u958b\u767c\u548c\u5546\u696d\u5316\u6b0a\u76ca\u3002 \u300c\u6211\u5011\u5f88\u9ad8\u82083\u671f\u81e8\u5e8a\u8a66\u9a57PALISADE-2\u7684\u7d50\u679c\u9032\u4e00\u6b65\u8b49\u5be6\u4e862\u671f\u7814\u7a76\u4e2d\u6240\u770b\u5230\u7684\u60c5\u6cc1\uff0c\u4e26\u986f\u793a\u4e86Fasedienol\u7684\u5de8\u5927\u6f5b\u529b\uff0c\u5176\u65b0\u7a4e\u800c\u7368\u7279\u7684\u4f5c\u7528\u6a5f\u5236\uff0c\u53ef\u4ee5\u6539\u8b8a\u7f8e\u570b\u8d85\u904e2500\u842c\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u53ca\u5168\u7403\u6578\u767e\u842c\u60a3\u8005\u7684\u6cbb\u7642\u53ef\u80fd\u6027\u300d\uff0cVistagen\u9996\u5e2d\u57f7\u884c\u5b98Shawn Singh\u8aaa\u3002\u300c\u4f5c\u70ba\u4e00\u985e\u65b0\u578b\u85e5\u7269\uff0c\u6211\u5011\u7684\u4fe1\u606f\u7d20\u9f3b\u5674\u5291\u7ba1\u7dda\u5177\u6709\u6539\u8b8a\u773e\u591a\u6cbb\u7642\u9818\u57df\u683c\u5c40\u7684\u6f5b\u529b\u3002\u6b63\u59823\u671f\u8a66\u9a57\u6240\u8b49\u660e\u7684\u90a3\u6a23\uff0cFasedienol\u8655\u65bc\u8a72\u985e\u85e5\u7269\u7684\u9818\u5148\u5730\u4f4d\uff0c\u5176\u6f5b\u529b\u70ba\u6210\u70ba20\u591a\u5e74\u4f86\u9996\u500b\u91dd\u5c0d\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u7684\u5168\u65b0\u85e5\u7269\u985e\u5225\u5960\u5b9a\u4e86\u57fa\u790e\u3002\u300d \u85f9\u7766\u91ab\u7642\u9996\u5e2d\u57f7\u884c\u5b98\u8d99\u5927\u582f\u535a\u58eb\u8a55\u8ad6\u9053\uff1a\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u770b\u5230PALISADE-2\u8a66\u9a57\u7684\u7d50\u679c\u8b49\u660e\u4e86Fasedienol\u5728\u6cbb\u7642\u793e\u4ea4\u7126\u616e\u969c\u7919\u65b9\u9762\u7684\u6f5b\u529b\uff0c\u4e26\u671f\u5f85\u8207Vistagen\u5408\u4f5c\uff0c\u70ba\u4e2d\u570b\uff0c\u97d3\u570b\u548c\u6771\u5357\u4e9e\u65e5\u76ca\u589e\u9577\u7684\u793e\u4ea4\u7126\u616e\u969c\u7919\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002\u300d \u4e3b\u8981\u7642\u6548\u7d42\u9ede PALISADE-2\u8a66\u9a57\uff08n=141\uff09\u9054\u5230\u4e86\u4e3b\u8981\u7642\u6548\u7d42\u9ede\uff0c\u5373\u00a0Fasedienol\uff08n = 70\uff09\u6cbb\u7642\u7d44\u8207\u5b89\u6170\u5291\u7d44\uff08n = 71\uff09\u5728\u516c\u958b\u6f14\u8b1b\u6311\u6230\u671f\u9593\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09\u7684\u5e73\u5747SUDS\u8a55\u5206\u76f8\u8f03\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u8b8a\u5316\u7684\u5dee\u7570\u3002\u8207\u5b89\u6170\u5291\u7d44\uff08LS\u5e73\u5747\u503c= -8.0\uff09\u76f8\u6bd4\uff0cFasedienol\u6cbb\u7642\u7d44SUDS\u5e73\u5747\u8a55\u5206\u8b8a\u5316\uff08\u6700\u5c0f\u4e8c\u4e58\uff08LS\uff09\u5e73\u5747\u503c= -13.8\uff09\u6709\u986f\u8457\u5dee\u7570\uff0c\u7d44\u9593\u5dee\u7570\u70ba-5.8\uff08p = 0.015\uff09\u3002 \u6b21\u8981\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u6b21\u8981\u7d42\u9ede\uff0cFasedienol\u548c\u5b89\u6170\u5291\u5728\u4ee5\u81e8\u5e8a\u91ab\u751f\u8a55\u4f30\u7684CGI-I\u91cf\u8868\u61c9\u7b54\u7387\u4e0a\u6709\u986f\u8457\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u88ab\u8a55\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba37.7%\uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba21.4%\uff08n = 71\uff09\uff08p = 0.033\uff09\u3002 \u63a2\u7d22\u6027\u7642\u6548\u7d42\u9ede \u8a72\u8a66\u9a57\u9054\u5230\u4e86\u4e00\u500b\u91cd\u8981\u7684\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u901a\u904e\u60a3\u8005\u5c0d\u75c5\u60c5\u8b8a\u5316\u7684\u7e3d\u9ad4\u5370\u8c61\uff08PGI-C\uff09\u91cf\u8868\u8861\u91cf\u7684Fasedienol\u548c\u5b89\u6170\u5291\u4e4b\u9593\u61c9\u7b54\u7387\u7684\u5dee\u7570\u3002\u61c9\u7b54\u8005\u70ba\u81ea\u6211\u8a55\u50f9\u70ba\u300c\u7126\u616e\u975e\u5e38\u660e\u986f\u6e1b\u5c11\u300d\u6216\u300c\u7126\u616e\u660e\u986f\u6e1b\u5c11\u300d\u7684\u60a3\u8005\uff0cFasedienol\u7d44\u70ba40.6% \uff08n = 70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n = 71\uff09\uff08p = 0.003\uff09\u3002 \u8a72\u8a66\u9a57\u9084\u9054\u5230\u4e86\u63a2\u7d22\u6027\u7d42\u9ede\uff0c\u5373\u5169\u7d44\u9593\u5f9e\u8a2a\u89962\uff08\u57fa\u7dda\uff09\u5230\u8a2a\u89963\uff08\u6cbb\u7642\u5f8c\uff09SUDS\u8a55\u5206\u6539\u5584\u81f3\u5c1120\u5206\uff08\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u6539\u5584\uff09\u7684\u60a3\u8005\u6bd4\u4f8b\uff0cFasedieno\u7d44\u70ba35.7%\uff08n=70\uff09\uff0c\u5b89\u6170\u5291\u7d44\u70ba18.6%\uff08n=71\uff09\uff0c\u5169\u7d44\u4e4b\u9593\u6709\u986f\u8457\u7d71\u8a08\u5b78\u5dee\u7570\uff08p=0.020\uff09\u3002 \u5b89\u5168\u6027 \u7814\u7a76\u986f\u793aFasedienol\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u5831\u544a\u91cd\u5ea6\u6216\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff08AEs\uff09\u3002\u5728\u6574\u500b\u7814\u7a76\u4e2d\uff0c\u6240\u6709\u6cbb\u7642\u671f\u9593\u51fa\u73fe\u7684\u4e0d\u826f\u4e8b\u4ef6\u5747\u70ba\u8f15\u5ea6\u6216\u4e2d\u5ea6\u3002\u5728Fasedienol\u6cbb\u7642\u7d44\u4e2d\uff0c\u672a\u5831\u544a\u767c\u751f\u7387\u8d85\u904e2%\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002 \u95dc\u65bc 3 \u671f PALISADE-2 \u8a66\u9a57 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