{"id":164796,"date":"2023-07-20T08:10:00","date_gmt":"2023-07-20T00:10:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=164796"},"modified":"2023-07-20T08:10:00","modified_gmt":"2023-07-20T00:10:00","slug":"%e7%94%98%e8%90%8a%e5%ae%a3%e4%bd%88%e6%b3%95%e5%b0%bc%e9%86%87x%e5%8f%97%e9%ab%94%e6%bf%80%e5%8b%95%e5%8a%91asc42%e6%b2%bb%e7%99%82%e5%8e%9f%e7%99%bc%e6%80%a7%e8%86%bd%e6%b1%81%e6%80%a7%e8%86%bd","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=164796","title":{"rendered":"\u7518\u840a\u5ba3\u4f48\u6cd5\u5c3c\u9187X\u53d7\u9ad4\u6fc0\u52d5\u5291ASC42\u6cbb\u7642\u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u7684II\u671f\u81e8\u5e8a\u8a66\u9a57\u5b8c\u6210\u60a3\u8005\u5165\u7d44"},"content":{"rendered":"<div>\n<p><i>&#8212;<\/i><i>\u7518\u840a\u9810\u8a08\u5c07\u65bc<\/i><i>2023<\/i><i>\u5e74\u5e95\u516c\u4f48<\/i><i>II<\/i><i>\u671f\u81e8\u5e8a\u8a66\u9a57\u7684\u9802\u7dda\u6578\u64da<\/i><\/p>\n<p>\u4e0a\u6d772023\u5e747\u670820\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; 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Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases [J]. Hepatology 2019, 69(1): 394-419. DOI: 10.1002\/hep.30145.<\/p>\n<p>[2] Nevens, Frederik et al. &#8220;A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.&#8221; The New England journal of medicine vol. 375,7 (2016): 631-43. doi:10.1056\/NEJMoa1509840.<\/p>\n<p>[3] \u4e2d\u83ef\u91ab\u5b78\u6703\u98a8\u6fd5\u75c5\u5b78\u5206\u6703, \u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u8a3a\u7642\u898f\u7bc4(2021)[J]. \u4e2d\u83ef\u5167\u79d1\u96dc\u8a8c, 2021, 60(8): 709-15. DOI: 10.3760\/cma.j.cn112138-20210520-00360.<\/p>\n<p>[4] Lu M, Zhou Y, Haller I V, et al. Increasing Prevalence of Primary Biliary Cholangitis and Reduced Mortality With Treatment [J]. Clin Gastroenterol Hepatol 2018, 16(8): 1342-50 e1. DOI: 10.1016\/j.cgh.2017.12.033.<\/p>\n<p><b>\u95dc\u65bc\u6b4c\u79ae<\/b><\/p>\n<p>\u6b4c\u79ae\u662f\u4e00\u5bb6\u5728\u9999\u6e2f\u8b49\u5238\u4ea4\u6613\u6240\u4e0a\u5e02\uff081672.HK\uff09\u7684\u5275\u65b0\u7814\u767c\u9a45\u52d5\u578b\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u6db5\u84cb\u4e86\u5f9e\u65b0\u85e5\u7814\u767c\u81f3\u751f\u7522\u548c\u5546\u696d\u5316\u7684\u5b8c\u6574\u50f9\u503c\u93c8\u3002\u6b4c\u79ae\u7684\u7ba1\u7406\u5718\u968a\u5177\u5099\u6df1\u539a\u7684\u5c08\u696d\u77e5\u8b58\u53ca\u512a\u79c0\u7684\u904e\u5f80\u6210\u5c31\uff0c\u5728\u5718\u968a\u7684\u5e36\u9818\u4e0b\uff0c\u6b4c\u79ae\u805a\u7126\u4e09\u5927\u81e8\u5e8a\u9700\u6c42\u5c1a\u672a\u6eff\u8db3\u7684\u91ab\u7642\u9818\u57df\uff1a\u75c5\u6bd2\u6027\u75be\u75c5\u3001\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e\u548c\u816b\u7624\uff0c\u4e26\u4ee5\u5168\u7403\u5316\u7684\u8996\u91ce\u9032\u884c\u4f48\u5c40\u3002\u6191\u501f\u5353\u8d8a\u7684\u57f7\u884c\u529b\uff0c\u6b4c\u79ae\u5feb\u901f\u63a8\u9032\u85e5\u7269\u7ba1\u7dda\u958b\u767c\uff0c\u722d\u53d6\u5728\u570b\u969b\u7af6\u722d\u4e2d\u4f54\u64da\u9818\u5148\u5730\u4f4d\u3002\u6b4c\u79ae\u76ee\u524d\u64c1\u670920+\u6b3e\u5728\u7814\u85e5\u7269, \u6700\u524d\u6cbf\u7684\u5019\u9078\u85e5\u7269\u5305\u62ecASC10\uff08\u547c\u5438\u9053\u5408\u80de\u75c5\u6bd2\u611f\u67d3\uff09\u3001ASC22\uff08\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u7652\uff09\u3001ASC40\uff08\u75e4\u7621\uff09\u3001ASC40\uff08\u5fa9\u767c\u6027\u81a0\u8cea\u6bcd\u7d30\u80de\u7624\uff09\u3001ASC40(\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e)\u3001ASC41(\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e)\u53caASC61\uff08\u665a\u671f\u5be6\u9ad4\u7624\uff09\u3002<\/p>\n<p>\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u656c\u8acb\u767b\u9304\u7db2\u7ad9\uff1a<a href=\"http:\/\/www.ascletis.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.ascletis.com<\/a>\u3002\u00a0<\/p>\n<p>\u00a0<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&#8212;\u7518\u840a\u9810\u8a08\u5c07\u65bc20&#8230;<\/p>\n","protected":false},"author":16,"featured_media":199219,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-164796","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases . Hepatology 2019, 69(1): 394-419. DOI: 10.1002\/hep.30145.  Nevens, Frederik et al. &quot;A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.&quot; The New England journal of medicine vol. 375,7 (2016): 631-43. doi:10.1056\/NEJMoa1509840.  \u4e2d\u83ef\u91ab\u5b78\u6703\u98a8\u6fd5\u75c5\u5b78\u5206\u6703, \u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u8a3a\u7642\u898f\u7bc4(2021). \u4e2d\u83ef\u5167\u79d1\u96dc\u8a8c, 2021, 60(8): 709-15. DOI: 10.3760\/cma.j.cn112138-20210520-00360.  Lu M, Zhou Y, Haller I V, et al. Increasing Prevalence of Primary Biliary Cholangitis and Reduced Mortality With Treatment . Clin Gastroenterol Hepatol 2018, 16(8): 1342-50 e1. 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Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases . Hepatology 2019, 69(1): 394-419. DOI: 10.1002\/hep.30145.  Nevens, Frederik et al. &quot;A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.&quot; The New England journal of medicine vol. 375,7 (2016): 631-43. doi:10.1056\/NEJMoa1509840.  \u4e2d\u83ef\u91ab\u5b78\u6703\u98a8\u6fd5\u75c5\u5b78\u5206\u6703, \u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u8a3a\u7642\u898f\u7bc4(2021). \u4e2d\u83ef\u5167\u79d1\u96dc\u8a8c, 2021, 60(8): 709-15. DOI: 10.3760\/cma.j.cn112138-20210520-00360.  Lu M, Zhou Y, Haller I V, et al. Increasing Prevalence of Primary Biliary Cholangitis and Reduced Mortality With Treatment . Clin Gastroenterol Hepatol 2018, 16(8): 1342-50 e1. DOI: 10.1016\/j.cgh.2017.12.033. \u95dc\u65bc\u6b4c\u79ae \u6b4c\u79ae\u662f\u4e00\u5bb6\u5728\u9999\u6e2f\u8b49\u5238\u4ea4\u6613\u6240\u4e0a\u5e02\uff081672.HK\uff09\u7684\u5275\u65b0\u7814\u767c\u9a45\u52d5\u578b\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u6db5\u84cb\u4e86\u5f9e\u65b0\u85e5\u7814\u767c\u81f3\u751f\u7522\u548c\u5546\u696d\u5316\u7684\u5b8c\u6574\u50f9\u503c\u93c8\u3002\u6b4c\u79ae\u7684\u7ba1\u7406\u5718\u968a\u5177\u5099\u6df1\u539a\u7684\u5c08\u696d\u77e5\u8b58\u53ca\u512a\u79c0\u7684\u904e\u5f80\u6210\u5c31\uff0c\u5728\u5718\u968a\u7684\u5e36\u9818\u4e0b\uff0c\u6b4c\u79ae\u805a\u7126\u4e09\u5927\u81e8\u5e8a\u9700\u6c42\u5c1a\u672a\u6eff\u8db3\u7684\u91ab\u7642\u9818\u57df\uff1a\u75c5\u6bd2\u6027\u75be\u75c5\u3001\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e\u548c\u816b\u7624\uff0c\u4e26\u4ee5\u5168\u7403\u5316\u7684\u8996\u91ce\u9032\u884c\u4f48\u5c40\u3002\u6191\u501f\u5353\u8d8a\u7684\u57f7\u884c\u529b\uff0c\u6b4c\u79ae\u5feb\u901f\u63a8\u9032\u85e5\u7269\u7ba1\u7dda\u958b\u767c\uff0c\u722d\u53d6\u5728\u570b\u969b\u7af6\u722d\u4e2d\u4f54\u64da\u9818\u5148\u5730\u4f4d\u3002\u6b4c\u79ae\u76ee\u524d\u64c1\u670920+\u6b3e\u5728\u7814\u85e5\u7269, \u6700\u524d\u6cbf\u7684\u5019\u9078\u85e5\u7269\u5305\u62ecASC10\uff08\u547c\u5438\u9053\u5408\u80de\u75c5\u6bd2\u611f\u67d3\uff09\u3001ASC22\uff08\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u7652\uff09\u3001ASC40\uff08\u75e4\u7621\uff09\u3001ASC40\uff08\u5fa9\u767c\u6027\u81a0\u8cea\u6bcd\u7d30\u80de\u7624\uff09\u3001ASC40(\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e)\u3001ASC41(\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e)\u53caASC61\uff08\u665a\u671f\u5be6\u9ad4\u7624\uff09\u3002 \u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u656c\u8acb\u767b\u9304\u7db2\u7ad9\uff1awww.ascletis.com\u3002\u00a0 \u00a0\" \/>\n<meta property=\"og:url\" content=\"https:\/\/pingtungtimes.com.tw\/?p=164796\" \/>\n<meta property=\"og:site_name\" content=\"\u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/pingtungnews\" \/>\n<meta property=\"article:published_time\" content=\"2023-07-20T00:10:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/pingtungtimes.com.tw\/wp-content\/uploads\/2023\/02\/logo-150.png\" \/>\n<meta name=\"author\" content=\"\u7f8e\u901a\u793e\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/pingtungtimes.com.tw\/wp-content\/uploads\/2023\/02\/logo-150.png\" \/>\n<meta name=\"twitter:label1\" content=\"\u4f5c\u8005:\" \/>\n\t<meta name=\"twitter:data1\" content=\"\u7f8e\u901a\u793e\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u9810\u4f30\u95b1\u8b80\u6642\u9593\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 \u5206\u9418\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/?p=164796#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/?p=164796\"},\"author\":{\"name\":\"\u7f8e\u901a\u793e\",\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/#\\\/schema\\\/person\\\/683b937f29ec1537972f6c41e22a2cf3\"},\"headline\":\"\u7518\u840a\u5ba3\u4f48\u6cd5\u5c3c\u9187X\u53d7\u9ad4\u6fc0\u52d5\u5291ASC42\u6cbb\u7642\u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u7684II\u671f\u81e8\u5e8a\u8a66\u9a57\u5b8c\u6210\u60a3\u8005\u5165\u7d44\",\"datePublished\":\"2023-07-20T00:10:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/?p=164796\"},\"wordCount\":145,\"publisher\":{\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/?p=164796#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/wp-content\\\/uploads\\\/2023\\\/02\\\/logo-150.png\",\"articleSection\":[\"\u7f8e\u901a\u793e\"],\"inLanguage\":\"zh-TW\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/?p=164796\",\"url\":\"https:\\\/\\\/pingtungtimes.com.tw\\\/?p=164796\",\"name\":\"\u7518\u840a\u5ba3\u4f48\u6cd5\u5c3c\u9187X\u53d7\u9ad4\u6fc0\u52d5\u5291ASC42\u6cbb\u7642\u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u7684II\u671f\u81e8\u5e8a\u8a66\u9a57\u5b8c\u6210\u60a3\u8005\u5165\u7d44 - 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Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases . Hepatology 2019, 69(1): 394-419. DOI: 10.1002\\\/hep.30145. Nevens, Frederik et al. \\\"A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.\\\" The New England journal of medicine vol. 375,7 (2016): 631-43. doi:10.1056\\\/NEJMoa1509840. \u4e2d\u83ef\u91ab\u5b78\u6703\u98a8\u6fd5\u75c5\u5b78\u5206\u6703, \u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u8a3a\u7642\u898f\u7bc4(2021). \u4e2d\u83ef\u5167\u79d1\u96dc\u8a8c, 2021, 60(8): 709-15. DOI: 10.3760\\\/cma.j.cn112138-20210520-00360. Lu M, Zhou Y, Haller I V, et al. Increasing Prevalence of Primary Biliary Cholangitis and Reduced Mortality With Treatment . Clin Gastroenterol Hepatol 2018, 16(8): 1342-50 e1. DOI: 10.1016\\\/j.cgh.2017.12.033. \u95dc\u65bc\u6b4c\u79ae 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Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases . Hepatology 2019, 69(1): 394-419. DOI: 10.1002\/hep.30145.  Nevens, Frederik et al. \"A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.\" The New England journal of medicine vol. 375,7 (2016): 631-43. doi:10.1056\/NEJMoa1509840.  \u4e2d\u83ef\u91ab\u5b78\u6703\u98a8\u6fd5\u75c5\u5b78\u5206\u6703, \u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u8a3a\u7642\u898f\u7bc4(2021). \u4e2d\u83ef\u5167\u79d1\u96dc\u8a8c, 2021, 60(8): 709-15. DOI: 10.3760\/cma.j.cn112138-20210520-00360.  Lu M, Zhou Y, Haller I V, et al. Increasing Prevalence of Primary Biliary Cholangitis and Reduced Mortality With Treatment . Clin Gastroenterol Hepatol 2018, 16(8): 1342-50 e1. 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Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases . Hepatology 2019, 69(1): 394-419. DOI: 10.1002\/hep.30145.  Nevens, Frederik et al. \"A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.\" The New England journal of medicine vol. 375,7 (2016): 631-43. doi:10.1056\/NEJMoa1509840.  \u4e2d\u83ef\u91ab\u5b78\u6703\u98a8\u6fd5\u75c5\u5b78\u5206\u6703, \u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u8a3a\u7642\u898f\u7bc4(2021). \u4e2d\u83ef\u5167\u79d1\u96dc\u8a8c, 2021, 60(8): 709-15. DOI: 10.3760\/cma.j.cn112138-20210520-00360.  Lu M, Zhou Y, Haller I V, et al. Increasing Prevalence of Primary Biliary Cholangitis and Reduced Mortality With Treatment . Clin Gastroenterol Hepatol 2018, 16(8): 1342-50 e1. 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Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases . Hepatology 2019, 69(1): 394-419. DOI: 10.1002\/hep.30145. Nevens, Frederik et al. \"A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.\" The New England journal of medicine vol. 375,7 (2016): 631-43. doi:10.1056\/NEJMoa1509840. \u4e2d\u83ef\u91ab\u5b78\u6703\u98a8\u6fd5\u75c5\u5b78\u5206\u6703, \u539f\u767c\u6027\u81bd\u6c41\u6027\u81bd\u7ba1\u708e\u8a3a\u7642\u898f\u7bc4(2021). \u4e2d\u83ef\u5167\u79d1\u96dc\u8a8c, 2021, 60(8): 709-15. DOI: 10.3760\/cma.j.cn112138-20210520-00360. Lu M, Zhou Y, Haller I V, et al. Increasing Prevalence of Primary Biliary Cholangitis and Reduced Mortality With Treatment . Clin Gastroenterol Hepatol 2018, 16(8): 1342-50 e1. 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