{"id":158903,"date":"2023-06-25T20:00:00","date_gmt":"2023-06-25T12:00:00","guid":{"rendered":"https:\/\/pingtungtimes.com.tw\/?p=158903"},"modified":"2023-06-25T20:00:00","modified_gmt":"2023-06-25T12:00:00","slug":"%e9%a8%b0%e7%9b%9b%e5%8d%9a%e8%97%a5%e5%ae%a3%e5%b8%83%e5%85%b6%e5%90%88%e4%bd%9c%e4%bc%99%e4%bc%b4%e5%9c%a82023%e5%b9%b4easltm%e5%a4%a7%e6%9c%83%e4%b8%8a%e5%85%ac%e5%b8%83%e7%9a%84%e6%9c%80","status":"publish","type":"post","link":"https:\/\/pingtungtimes.com.tw\/?p=158903","title":{"rendered":"\u9a30\u76db\u535a\u85e5\u5ba3\u5e03\u5176\u5408\u4f5c\u4f19\u4f34\u57282023\u5e74EASL(TM)\u5927\u6703\u4e0a\u516c\u5e03\u7684\u6700\u65b0\u6578\u64da\u5f37\u8abf\u4e86HBV\u529f\u80fd\u6027\u6cbb\u6108\u7684\u6f5b\u529b"},"content":{"rendered":"<div>\n<table name=\"logo_release\" border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul type=\"disc\">\n<li><i>BRII-835+PEG-IFN-<\/i><i>\u237a<\/i><i>\u7814\u7a76\u7684\u6700\u65b0\u7a81\u7834<\/i><i>\uff08<\/i><i>late<\/i>&#8211;<i>breaking\uff09<\/i><i>\u6578\u64da\u8868\u660e\uff0c\u6cbb\u7642\u7d50\u675f\u6642\u7684\u6297\u4e59\u809d\u8868\u9762\u6297\u9ad4\uff08<\/i><i>HBs\uff09\u6ef4\u5ea6\u8207\u6cbb\u7642\u7d50\u675f\u5f8c24\u5468\u7684\u4e59\u809d\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6301\u7e8c\u4e0b\u964d\u76f8\u95dc<\/i><\/li>\n<li><i>\u65b0\u6578\u64da\u986f\u793a\uff0c\u63a5\u7a2e<\/i><i>VBI\u7684<\/i><i>\u4e09<\/i><i>\u6297\u539f\u9810\u9632\u6027\u4e59\u578b\u809d\u708e\u75ab\u82d7<\/i><i>PreHevbrio<sup>\u00ae<\/sup>\u5f8c\uff0c\u6297HBs\u6ef4\u5ea6<\/i><i>\u8868\u73fe\u51fa<\/i><i>\u66f4\u4f73\u7684\u7a69\u5065\u6027\u548c\u6301\u4e45\u6027<\/i><\/li>\n<li><i>\u6578\u64da\u652f\u6301\u7e7c\u7e8c\u958b\u767c<\/i><i>BRII-835\u3001BRII-877\u548cBRII-179\uff0c\u4ee5<\/i><i>\u5be6\u73fe<\/i><i>\u5728\u5ee3\u6cdb<\/i><i>HBV\u60a3\u8005\u4eba\u7fa4\u4e2d<\/i><i>\u7684<\/i><i>\u6700\u4f73\u529f\u80fd\u6027\u6cbb\u6108<\/i><i>\u6548\u679c<\/i><\/li>\n<\/ul>\n<p>\u4e2d\u570b\u5317\u4eac\u548c\u7f8e\u570b\u5317\u5361\u7f85\u4f86\u7d0d\u5dde\u9054\u52d2\u59c62023\u5e746\u670825\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; <a href=\"https:\/\/www.briibio.com\/cn\" target=\"_blank\" rel=\"nofollow noopener\">\u9a30\u76db\u535a\u85e5\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8<\/a>\uff08\u300c\u9a30\u76db\u535a\u85e5\u300d\uff0c\u300c\u6211\u5011\u300d\u6216\u300c\u516c\u53f8\u300d\uff0c\u80a1\u7968\u4ee3\u78bc\uff1a2137.HK\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u65bc\u91dd\u5c0d\u60a3\u8005\u9700\u6c42\u672a\u88ab\u6eff\u8db3\u7684\u75be\u75c5\u958b\u767c\u6cbb\u7642\u65b9\u6848\uff0c\u4ee5\u6539\u5584\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u548c\u6cbb\u7642\u9078\u64c7\u7684\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u4eca\u5929\u5ba3\u5e03\uff0c\u5176\u6230\u7565\u5408\u4f5c\u4f19\u4f34Vir Biotechnology, Inc.\uff08\u300cVir\u300d\uff0cNASDAQ\uff1aVIR\uff09\u548cVBI Vaccines, Inc.\uff08\u300cVBI\u300d\uff0cNASDAQ\uff1aVBIV\uff09\u57282023\u5e74\u6b50\u6d32\u809d\u9ad2\u7814\u7a76\u5354\u6703\uff08EASL\uff09\u5927\u6703\u4e0a\u516c\u5e03\u4e86\u591a\u9805\u6cbb\u7642\u548c\u9810\u9632\u6162\u6027\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u7684\u81e8\u5e8a\u7814\u7a76\u7d50\u679c\uff0c\u9032\u4e00\u6b65\u652f\u6301\u9a30\u76db\u535a\u85e5\u7684\u7522\u54c1\u4f5c\u70ba\u6f5b\u5728\u540c\u985e\u6700\u4f73\u7684\u6162\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u6108\u7642\u6cd5\u7684\u81e8\u5e8a\u8a55\u4f30\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder1\">\n<\/p><\/div>\n<p>\u9a30\u76db\u535a\u85e5\u50b3\u67d3\u75c5\u6cbb\u7642\u9818\u57df\u8ca0\u8cac\u4ebaDavid Margolis\u535a\u58eb\u8868\u793a\uff0c\u300c\u8207\u6211\u5011\u7684\u5408\u4f5c\u4f19\u4f34\u4e00\u8d77\uff0c\u6211\u5011\u671f\u5f85\u501f\u52a9\u9019\u4e9b\u5f9e\u8a66\u9a57\u4e2d\u7372\u5f97\u7684\u4ee4\u4eba\u8208\u596e\u7684\u6d1e\u5bdf\u4f86\u4e0d\u65b7\u5b8c\u5584\u6211\u5011\u7684\u79d1\u5b78\u7b56\u7565\u3002\u6211\u5011\u7cbe\u5fc3\u8a2d\u8a08\u548c\u69cb\u5efa\u7684\u9019\u500bHBV\u7522\u54c1\u7d44\u5408\uff0c\u4f7f\u6211\u5011\u80fd\u5920\u63a2\u7d22\u591a\u7a2e\u65b0\u578b\u806f\u5408\u6cbb\u7642\u65b9\u6848\uff0c\u4ee5\u63d0\u9ad8\u5ee3\u6cdbHBV\u60a3\u8005\u4eba\u7fa4\u5be6\u73fe\u9ad8\u529f\u80fd\u6027\u6cbb\u6108\u7387\u7684\u53ef\u80fd\u6027\u3002\u540c\u6642\uff0c\u6211\u5011\u5c07\u7e7c\u7e8c\u81f4\u529b\u65bc\u4ee3\u8868\u60a3\u8005\u63a8\u52d5\u79d1\u5b78\u5275\u65b0\u3002\u300d<\/p>\n<p>\u5728\u6700\u65b0\u7a81\u7834\u53e3\u982d\u5831\u544a\uff08late-breaker oral presentation\uff09\u4e2d\uff0cVir\u516c\u5e03\u4e86\u4e00\u98052\u671f\u8a66\u9a57\u768424\u5468\u96a8\u8a2a\u6578\u64da\u3002\u8a72\u6578\u64da\u8868\u660e\uff0c\u5728\u6700\u957748\u5468\u7684\u805a\u4e59\u4e8c\u9187\u5e72\u64fe\u7d20\u237a\uff08PEG-IFN-\u237a\uff09\u7642\u7a0b\u57fa\u790e\u4e0a\uff0c\u7d66\u85e5VIR-2218\uff08BRII-835\uff0924\u621648\u5468\u6642\uff0c26%\uff088\/31\uff09\u7684\u75c5\u6bd2\u5b78\u6291\u5236\u7684\u6162\u4e59\u809d\u53d7\u8a66\u8005\u5728\u6cbb\u7642\u7d50\u675f\u6642\u5be6\u73fe\u4e86HBsAg\u6e05\u9664\u3002<\/p>\n<ul type=\"disc\">\n<li>16%\uff085\/31\uff09\u7684\u53d7\u8a66\u8005\u5728\u6cbb\u7642\u7d50\u675f\u5f8c24\u5468HBsAg\u6301\u7e8c\u6e05\u9664\uff1b5\u4f8b\u53d7\u8a66\u8005\u4e2d\u67092\u4f8b\u57fa\u7ddaHBsAg\u6c34\u5e73\u5927\u65bc1000 IU\/mL\u3002\u96a8\u8a2a\u671f\u9593\u672a\u89c0\u5bdf\u5230\u65b0\u7684\u5b89\u5168\u6027\u554f\u984c\u3002<\/li>\n<li>\u5728\u6cbb\u7642\u7d50\u675f\u6642\u6297HBs\u6ef4\u5ea6\u5927\u65bc500 mIU\/mL\u76844\u4f8b\u53d7\u8a66\u8005\uff0c\u5728\u6cbb\u7642\u7d50\u675f\u5f8c24\u5468\u5747\u5be6\u73fe\u4e86\u6301\u7e8c\u7684HBsAg\u6e05\u9664\uff0c\u8868\u660e\u6297HBs\u6ef4\u5ea6\u6709\u53ef\u80fd\u4f5c\u70ba\u6cbb\u7642\u671f\u9593\u6301\u7e8c\u61c9\u7b54\u7684\u9810\u6e2c\u6307\u6a19\u3002<\/li>\n<\/ul>\n<p>\u5728\u53e6\u4e00\u4efd\u53e3\u982d\u5831\u544a\u4e2d\uff0cVir\u5ba3\u5e03\u4e862\u671fMARCH\u8a66\u9a57A\u90e8\u5206\u6cbb\u7642\u5f8c48\u5468\u7684\u6578\u64da\u3002VIR-2218\uff08BRII-835\uff09\u548cVIR-3434\uff08BRII-877\uff09\u4f5c\u70ba\u6162\u6027HBV\u611f\u67d3\u7684\u806f\u5408\u6cbb\u7642\uff0c\u5728\u806f\u5408\u7d66\u85e55\u5468\u621612\u5468\u5f8c\uff0c\u53d7\u8a66\u8005\u7684HBsAg\u6c34\u5e73\u964d\u4f4e2.7-3.1 log<sub>10<\/sub> IU\/mL\uff0c90%\u7684\u53d7\u8a66\u8005\u5728\u8a72\u77ed\u671f\u6cbb\u7642\u7d50\u675f\u6642HBsAg\u6c34\u5e73\u5c0f\u65bc10 IU\/mL\u3002<\/p>\n<ul type=\"disc\">\n<li>\u5927\u591a\u6578\u53d7\u8a66\u8005\u9054\u5230\u4ee5\u4e0b\u6240\u6709\u6307\u6a19\u8981\u6c42\uff0c\u7b26\u5408\u505c\u6b62\u6838\u7518\u9178\u9006\u8f49\u9304\u9176\u6291\u5236\u5291\uff08NRTI\uff09\u6cbb\u7642\u7684\u6a19\u51c6\uff1aHBsAg\u6c34\u5e73\u5c0f\u65bc100 IU\/mL\uff0c\u4e14\u8f03\u57fa\u7ddaHBsAg\u6c34\u5e73\u4e0b\u964d\u5927\u65bc\u6216\u7b49\u65bc1 log<sub>10<\/sub> IU\/mL\uff0cHBV DNA\u4f4e\u65bc\u5b9a\u91cf\u4e0b\u9650\uff08LLOQ\uff09\uff0cHBeAg\u9670\u6027\u4e14ALT\u6c34\u5e73\u5c0f\u65bc\u6216\u7b49\u65bc2\u500d\u6b63\u5e38\u503c\u4e0a\u9650\u300267%\uff084\/6\uff09\u7684\u53d7\u8a66\u8005\u5728\u6700\u5f8c\u4e00\u6b21\u5df2\u5b8c\u6210\u7684\u96a8\u8a2a\u4e2d\u4ecd\u7121\u9700\u63a5\u53d7NRTI\u6cbb\u7642\u3002<\/li>\n<li>VIR-2218\uff08BRII-835\uff09\u548cVIR-3434\uff08BRII-877\uff09\u806f\u5408\u6cbb\u7642\u7e3d\u9ad4\u8010\u53d7\u6027\u826f\u597d\uff0c\u4e3b\u8981\u8207\u8f15\u5ea6\u4e0d\u826f\u4e8b\u4ef6\u76f8\u95dc\u3002\u6240\u6709\u6cbb\u7642\u76f8\u95dc\u7684\u4e0d\u826f\u4e8b\u4ef6\u5747\u70ba1\u7d1a\uff0c\u6c92\u6709\u7d42\u6b62\u7814\u7a76\u7684\u60c5\u6cc1\u767c\u751f\u3002<\/li>\n<\/ul>\n<p>\u53e6\u5916\uff0c\u5728\u4e00\u4efd\u6d77\u5831\u5c55\u793a\u4e2d\uff0cVir\u5f37\u8abf\u4e86\u4e00\u9805\u5728\u6162\u6027HBV\u611f\u67d3\u60a3\u8005\u4e2d\u9032\u884c\u7684VIR-3434\uff08BRII-877\uff091\u671f\u81e8\u5e8a\u8a66\u9a57\u55ae\u6b21\u7d66\u85e5\u7684\u85e5\u4ee3\u52d5\u529b\u5b78\u7279\u5f81\uff0c\u8a72\u6578\u64da\u652f\u6301\u7e7c\u7e8c\u5c0dVIR-3434\uff08BRII-877\uff09\u9032\u884c\u8a55\u4f30\u3002<\/p>\n<ul type=\"disc\">\n<li>\u7121\u8ad6\u57fa\u7ddaHBsAg\u6c34\u5e73\u5982\u4f55\uff0c\u5728300 mg\u5291\u91cf\u4e0b\u5747\u89c0\u5bdf\u5230\u6700\u9ad8\u548c\u6700\u6301\u4e45\u7684\u6e38\u96e2VIR-3434\uff08BRII-877\uff09\u66b4\u9732\u91cf\u3002\u8a55\u4f30\u7684\u5176\u4ed6\u5291\u91cf\u5305\u62ec6 mg\u300118 mg\u548c75 mg\u3002<\/li>\n<li>VIR-3434\uff08BRII-877\uff09\u5728\u57fa\u7ddaHBsAg\u8f03\u9ad8\u7684\u53d7\u8a66\u8005\u4e2d\u7684\u7d42\u672b\u534a\u8870\u671f\u8f03\u77ed\uff0c\u6e05\u9664\u901f\u5ea6\u66f4\u5feb\u3002<\/li>\n<\/ul>\n<p>\u6b64\u5916\uff0cVBI\u9084\u516c\u5e03\u4e86\u95dc\u9375\u60273\u671f\u7814\u7a76PROTECT\u53d7\u8a66\u8005\u4e9e\u7d44\uff0c\u5728\u514d\u75ab\u63a5\u7a2e\u9810\u9632\u6027\u4e09\u6297\u539f\u75ab\u82d7PreHevbrio<sup>\u00ae<\/sup>\u5f8c\u9577\u90543.5\u5e74\u5167\u7684\u96a8\u8a2a\u6578\u64da\uff0c\u4ee5\u78ba\u5b9a\u514d\u75ab\u61c9\u7b54\u7684\u7a0b\u5ea6\u548c\u6301\u7e8c\u6642\u9593\u3002PreHevbrio\u662f\u7531\u8207BRII-179\uff08VBI-2601\uff09\u75c5\u6bd2\u6a23\u9846\u7c92\u4e2d\u91cd\u7d44HBV\u8868\u9762\u6297\u539fPreS1\u3001PreS2\u548cS\u76f8\u540c\u7684\u6297\u539f\u7d44\u6210\u3002<\/p>\n<ul type=\"disc\">\n<li>\u5728\u6240\u6709\u6e2c\u91cf\u6642\u9593\u9ede\uff0c\u8207\u63a5\u7a2eEngerix-B<sup>\u00ae<\/sup>\u7684\u53d7\u8a66\u8005\u76f8\u6bd4\uff0c\u63a5\u7a2ePreHevbrio\u7684\u53d7\u8a66\u8005\u7684\u5e73\u5747HBsAg\u6297\u9ad4\u6ef4\u5ea6\u986f\u8457\u63d0\u9ad8\uff08P&lt;0.0001\uff09\u3002<\/li>\n<li>\u6578\u64da\u8868\u660ePreHevbrio\u8a98\u5c0e\u4e86\u91dd\u5c0dPre-S1\u548cPre-S2\u86cb\u767d\u7684T\u7d30\u80de\u61c9\u7b54\uff0c\u4e26\u8207\u8f03\u9ad8\u7684\u6297HBs\u6ef4\u5ea6\u76f8\u95dc\u3002<\/li>\n<li>\u57283.5\u5e74\u7684\u96a8\u8a2a\u671f\u9593\uff0c\u63a5\u7a2ePreHevbrio\u7684\u53d7\u8a66\u8005\u7684\u5e73\u5747\u6297HBs\u6ef4\u5ea6\u662f\u63a5\u7a2eEngerix-B\u7684\u53d7\u8a66\u8005\u76845.1\u500d\uff081287.2 vs. 253.7 mIU\/mL\uff09\uff0c\u9019\u8868\u660e\u8207Engerix-B\u76f8\u6bd4\uff0cPreHevbrio\u7684T\u7d30\u80de\u61c9\u7b54\u53ef\u80fd\u6709\u52a9\u65bc\u5be6\u73fe\u66f4\u52a0\u6301\u4e45\u548c\u5f37\u70c8\u7684\u9ad4\u6db2\u514d\u75ab\u61c9\u7b54\u3002<\/li>\n<\/ul>\n<p>\u4f5c\u70ba\u9a30\u76db\u535a\u85e5\u958b\u767cHBV\u529f\u80fd\u6027\u6cbb\u6108\u7368\u7279\u65b9\u6cd5\u7684\u4e00\u90e8\u5206\uff0c\u9a30\u76db\u535a\u85e5\u8207\u5176\u5408\u4f5c\u4f19\u4f34\u6b63\u5728\u9032\u884c\u591a\u9805\u7814\u7a76\uff0c\u5305\u62ecBRII-835\uff08VIR-2218\uff09\u548cBRII-179\uff08VBI-2601\uff09\u806f\u5408\u7528\u85e5\u3001BRII-179\u548cPEG-IFN-\u237a\u806f\u5408\u7528\u85e5\u3001BRII-835\uff08VIR-2218\uff09\u3001BRII-877\uff08VIR-3434\uff09\u806f\u5408\u6216\u4e0d\u806f\u5408PEG-IFN-\u237a\uff0c\u4ee5\u53caBRII-835\uff08VIR-2218\uff09\u548c\/\u6216BRII-877\uff08VIR-3434\uff09\u8207\u5176\u4ed6\u85e5\u7269\u7684\u806f\u5408\u7528\u85e5\u3002\u8fc4\u4eca\u70ba\u6b62\uff0c\u5206\u5225\u6709\u7d04390\u3001240\u548c180\u4f8b\u53d7\u8a66\u8005\u63a5\u53d7\u4e86BRII-835\uff08VIR-2218\uff09\u3001BRII-877\uff08VIR-3434\uff09\u548cBRII-179\uff08VBI-2601\uff09\u7684\u6cbb\u7642\u3002<\/p>\n<p><b>\u95dc\u65bc<\/b><b>BRII-835\uff08VIR-2218\uff09<\/b><\/p>\n<p>BRII-835\uff08VIR-2218\uff09\u662f\u4e00\u7a2e\u9776\u5411\u6240\u6709HBV\u75c5\u6bd2RNA\u7684 GalNAc\u5076\u806f\u7684\u5c0f\u5e72\u64fe\u6838\u7cd6\u6838\u9178\uff08siRNA\uff09\uff0c\u5176\u53ef\u963b\u65b7HBV\u7684\u75c5\u6bd2\u8f49\u9304\u3001\u6e1b\u5c11\u75c5\u6bd2\u86cb\u767d\u4e26\u7de9\u89e3\u514d\u75ab\u6291\u5236\u3002<\/p>\n<p><b>\u95dc\u65bc<\/b><b>BRII-877\uff08VIR-3434\uff09<\/b><\/p>\n<p>BRII-877\uff08VIR-3434\uff09\u662f\u4e00\u7a2e\u76ae\u4e0b\u6ce8\u5c04\u7684\u7814\u7a76\u6027HBV\u55ae\u514b\u9686\u4e2d\u548c\u6297\u9ad4\uff0c\u65e8\u5728\u963b\u65b7\u6240\u670910\u7a2e\u57fa\u56e0\u578b\u7684HBV\u9032\u5165\u809d\u7d30\u80de\uff0c\u4e26\u964d\u4f4e\u8840\u6db2\u4e2d\u75c5\u6bd2\u9846\u7c92\u548c\u4e9e\u75c5\u6bd2\u9846\u7c92\u7684\u6c34\u5e73\u3002BRII-877\uff08VIR-3434\uff09\u7d50\u5408\u4e86Xencor\u7684Xtend\u2122\u548c\u5176\u4ed6Fc\u6280\u8853\uff0c\u901a\u904e\u9019\u4e9b\u6539\u9020\u6709\u5e0c\u671b\u5728\u611f\u67d3\u60a3\u8005\u4e2d\u4f5c\u70ba\u91dd\u5c0dHBV\u7684T\u7d30\u80de\u75ab\u82d7\uff0c\u4e26\u5177\u6709\u5ef6\u9577\u7684\u534a\u8870\u671f\u3002<\/p>\n<p><b>\u95dc\u65bc<\/b><b>BRII-179\uff08VBI-2601\uff09<\/b><\/p>\n<p>BRII-179\uff08VBI-2601\uff09\u662f\u4e00\u7a2e\u57fa\u65bc\u91cd\u7d44\u86cb\u767d\u8cea\u7684\u65b0\u578bHBV \u514d\u75ab\u6cbb\u7642\u5019\u9078\u85e5\u7269\uff0c\u53ef\u8868\u9054Pre-S1 \u3001 Pre-S2 \u548c S HBV \u8868\u9762\u6297\u539f\uff0c\u65e8\u5728\u8a98\u5c0e\u589e\u5f37B \u7d30\u80de\u548c T \u7d30\u80de\u7684\u514d\u75ab\u61c9\u7b54\u3002<\/p>\n<p><b>\u95dc\u65bc\u4e59\u578b\u809d\u708e<\/b><\/p>\n<p>\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u662f\u4e16\u754c\u4e0a\u6700\u91cd\u5927\u7684\u50b3\u67d3\u75c5\u5a01\u8105\u4e4b\u4e00\uff0c\u5168\u7403\u611f\u67d3\u4eba\u6578\u8d85\u904e2.9\u5104\u3002<sup>1<\/sup>\u6162\u6027HBV\u611f\u67d3\u662f\u809d\u9ad2\u75be\u75c5\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u6bcf\u5e74\u7d04\u670982\u842c\u4eba\u6b7b\u65bc\u6162\u6027HBV\u611f\u67d3\u7684\u4e26\u767c\u75c7\u3002<sup>1<\/sup>\u4e2d\u570bHBV\u611f\u67d3\u4eba\u6578\u90548,700\u842c\uff0c\u975e\u5e38\u503c\u5f97\u95dc\u6ce8\u3002<sup>2<\/sup><\/p>\n<p><b>\u95dc\u65bc\u9a30\u76db\u535a\u85e5<\/b><\/p>\n<p>\u9a30\u76db\u535a\u85e5\uff08\u80a1\u7968\u4ee3\u78bc\uff1a2137.HK\uff09\u662f\u4e00\u5bb6\u751f\u7269\u6280\u8853\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u91dd\u5c0d\u5b58\u5728\u5de8\u5927\u672a\u88ab\u6eff\u8db3\u7684\u60a3\u8005\u9700\u6c42\u3001\u6cbb\u7642\u624b\u6bb5\u6709\u9650\uff0c\u4ee5\u53ca\u7d66\u60a3\u8005\u5e36\u4f86\u56b4\u91cd\u793e\u6703\u75c5\u6065\u611f\u7684\u4e16\u754c\u6700\u5e38\u898b\u7684\u75be\u75c5\u958b\u767c\u5275\u65b0\u7642\u6cd5\u3002\u516c\u53f8\u5c08\u6ce8\u65bc\u50b3\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\uff0c\u6b63\u5728\u63a8\u9032\u4e00\u689d\u6db5\u84cb\u591a\u7a2e\u7368\u7279\u5019\u9078\u85e5\u7269\u7684\u7522\u54c1\u7ba1\u7dda\uff0c\u4e26\u901a\u904e\u9818\u5148\u7684\u9805\u76ee\u958b\u767c\u91dd\u5c0d\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u7684\u65b0\u578b\u529f\u80fd\u6027\u6cbb\u6108\u65b9\u6848\uff0c\u548c\u91dd\u5c0d\u7522\u5f8c\u6291\u90c1\u75c7\uff08PPD\uff09\u7684\u9996\u5275\u6cbb\u7642\u65b9\u6848\u3002\u5728\u5bcc\u6709\u9060\u898b\u5353\u8b58\u548c\u7d93\u9a57\u8c50\u5bcc\u7684\u9818\u5c0e\u5718\u968a\u5e36\u9818\u4e0b\uff0c\u516c\u53f8\u5728\u4f4d\u65bc\u7f85\u5229-\u9054\u52d2\u59c6\u3001\u820a\u91d1\u5c71\u7063\u5340\u3001\u5317\u4eac\u548c\u4e0a\u6d77\u7684\u4e3b\u8981\u751f\u7269\u6280\u8853\u4e2d\u5fc3\u958b\u5c55\u696d\u52d9\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f<a href=\"http:\/\/www.briibio.com\/\" target=\"_blank\" rel=\"nofollow noopener\">www.briibio.com<\/a>\u3002<\/p>\n<p><sup>1\u00a0<\/sup>World Health Organization. (<span class=\"xn-chron\">June 2022<\/span>). <i>Hepatitis B.<\/i> World Health Organization. Retrieved from <a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b<\/a>\u3001<br \/><sup>2<\/sup>\u00a0World Health Organization. <i>Hepatitis.<\/i> World Health Organization. Retrieved from <a href=\"https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C\" target=\"_blank\" rel=\"nofollow noopener\">https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C<\/a>.<\/p>\n<div class=\"PRN_ImbeddedAssetReference\" id=\"DivAssetPlaceHolder2\">  <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>BRII-835+PEG-IF&#8230;<\/p>\n","protected":false},"author":16,"featured_media":158904,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[40567],"tags":[],"class_list":["post-158903","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-40567"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO 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Inc.\uff08\u300cVBI\u300d\uff0cNASDAQ\uff1aVBIV\uff09\u57282023\u5e74\u6b50\u6d32\u809d\u9ad2\u7814\u7a76\u5354\u6703\uff08EASL\uff09\u5927\u6703\u4e0a\u516c\u5e03\u4e86\u591a\u9805\u6cbb\u7642\u548c\u9810\u9632\u6162\u6027\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u611f\u67d3\u7684\u81e8\u5e8a\u7814\u7a76\u7d50\u679c\uff0c\u9032\u4e00\u6b65\u652f\u6301\u9a30\u76db\u535a\u85e5\u7684\u7522\u54c1\u4f5c\u70ba\u6f5b\u5728\u540c\u985e\u6700\u4f73\u7684\u6162\u4e59\u809d\u529f\u80fd\u6027\u6cbb\u6108\u7642\u6cd5\u7684\u81e8\u5e8a\u8a55\u4f30\u3002     \u9a30\u76db\u535a\u85e5\u50b3\u67d3\u75c5\u6cbb\u7642\u9818\u57df\u8ca0\u8cac\u4ebaDavid 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presentation\uff09\u4e2d\uff0cVir\u516c\u5e03\u4e86\u4e00\u98052\u671f\u8a66\u9a57\u768424\u5468\u96a8\u8a2a\u6578\u64da\u3002\u8a72\u6578\u64da\u8868\u660e\uff0c\u5728\u6700\u957748\u5468\u7684\u805a\u4e59\u4e8c\u9187\u5e72\u64fe\u7d20\u237a\uff08PEG-IFN-\u237a\uff09\u7642\u7a0b\u57fa\u790e\u4e0a\uff0c\u7d66\u85e5VIR-2218\uff08BRII-835\uff0924\u621648\u5468\u6642\uff0c26%\uff088\/31\uff09\u7684\u75c5\u6bd2\u5b78\u6291\u5236\u7684\u6162\u4e59\u809d\u53d7\u8a66\u8005\u5728\u6cbb\u7642\u7d50\u675f\u6642\u5be6\u73fe\u4e86HBsAg\u6e05\u9664\u3002 16%\uff085\/31\uff09\u7684\u53d7\u8a66\u8005\u5728\u6cbb\u7642\u7d50\u675f\u5f8c24\u5468HBsAg\u6301\u7e8c\u6e05\u9664\uff1b5\u4f8b\u53d7\u8a66\u8005\u4e2d\u67092\u4f8b\u57fa\u7ddaHBsAg\u6c34\u5e73\u5927\u65bc1000 IU\/mL\u3002\u96a8\u8a2a\u671f\u9593\u672a\u89c0\u5bdf\u5230\u65b0\u7684\u5b89\u5168\u6027\u554f\u984c\u3002  \u5728\u6cbb\u7642\u7d50\u675f\u6642\u6297HBs\u6ef4\u5ea6\u5927\u65bc500 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1\u00a0World Health Organization. (June 2022). Hepatitis B. World Health Organization. Retrieved from https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b\u30012\u00a0World Health Organization. Hepatitis. World Health Organization. Retrieved from https:\/\/www.who.int\/china\/health-topics\/hepatitis#:~:text=There%20are%2087%20million%20people,living%20with%20chronic%20hepatitis%20C.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pingtungtimes.com.tw\/?p=158903\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u9a30\u76db\u535a\u85e5\u5ba3\u5e03\u5176\u5408\u4f5c\u4f19\u4f34\u57282023\u5e74EASL(TM)\u5927\u6703\u4e0a\u516c\u5e03\u7684\u6700\u65b0\u6578\u64da\u5f37\u8abf\u4e86HBV\u529f\u80fd\u6027\u6cbb\u6108\u7684\u6f5b\u529b - \u5c4f\u6771\u6642\u5831\u96fb\u5b50\u5831\" \/>\n<meta property=\"og:description\" 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1\u00a0World Health Organization. (June 2022). Hepatitis B. World Health Organization. Retrieved from https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b\u30012\u00a0World Health Organization. Hepatitis. World Health Organization. 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1\u00a0World Health Organization. (June 2022). Hepatitis B. World Health Organization. Retrieved from https:\\\/\\\/www.who.int\\\/news-room\\\/fact-sheets\\\/detail\\\/hepatitis-b\u30012\u00a0World Health Organization. Hepatitis. World Health Organization. Retrieved from 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1\u00a0World Health Organization. (June 2022). Hepatitis B. World Health Organization. Retrieved from https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b\u30012\u00a0World Health Organization. Hepatitis. World Health Organization. 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1\u00a0World Health Organization. (June 2022). Hepatitis B. World Health Organization. Retrieved from https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b\u30012\u00a0World Health Organization. Hepatitis. World Health Organization. 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1\u00a0World Health Organization. (June 2022). Hepatitis B. World Health Organization. Retrieved from https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hepatitis-b\u30012\u00a0World Health Organization. Hepatitis. World Health Organization. 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